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1OWD
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Substituted 2-Naphthamidine inhibitors of urokinase
分子名称: 6-[AMINO(IMINO)METHYL]-N-[(4R)-4-ETHYL-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL]-2-NAPHTHAMIDE, Urokinase-type plasminogen activator
著者Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L.
登録日2003-03-28
公開日2003-09-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution.
J.Med.Chem., 47, 2004
1OJZ
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The crystal structure of C3stau2 from S. aureus with NAD
分子名称: ADP-RIBOSYLTRANSFERASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Evans, H.R, Sutton, J.M, Holloway, D.E, Ayriss, J, Shone, C.C, Acharya, K.R.
登録日2003-07-16
公開日2003-08-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献The Crystal Structure of C3Stau2 from Staphylococcus Aureus and its Complex with Nad
J.Biol.Chem., 278, 2003
1OKB
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crystal structure of Uracil-DNA glycosylase from Atlantic cod (Gadus morhua)
分子名称: CHLORIDE ION, GLYCEROL, URACIL-DNA GLYCOSYLASE
著者Leiros, I, Moe, E, Lanes, O, Smalas, A.O, Willassen, N.P.
登録日2003-07-21
公開日2004-04-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Crystal Structure of Uracil-DNA Glycosylase from Atlantic Cod (Gadus Morhua) Reveals Cold-Adaptation Features
Acta Crystallogr.,Sect.D, 59, 2003
1OIL
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STRUCTURE OF LIPASE
分子名称: CALCIUM ION, LIPASE
著者Kim, K.K, Song, H.K, Shin, D.H, Suh, S.W.
登録日1996-12-06
公開日1997-05-15
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of a triacylglycerol lipase from Pseudomonas cepacia reveals a highly open conformation in the absence of a bound inhibitor.
Structure, 5, 1997
1OSP
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CRYSTAL STRUCTURE OF OUTER SURFACE PROTEIN A OF BORRELIA BURGDORFERI COMPLEXED WITH A MURINE MONOCLONAL ANTIBODY FAB
分子名称: FAB 184.1, OUTER SURFACE PROTEIN A
著者Li, H, Lawson, C.L.
登録日1996-11-23
公開日1997-04-21
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of Lyme disease antigen outer surface protein A complexed with an Fab.
Proc.Natl.Acad.Sci.USA, 94, 1997
1P0F
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Crystal Structure of the Binary Complex: NADP(H)-Dependent Vertebrate Alcohol Dehydrogenase (ADH8) with the cofactor NADP
分子名称: GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent ALCOHOL DEHYDROGENASE, ...
著者Rosell, A, Valencia, E, Pares, X, Fita, I, Farres, J, Ochoa, W.F.
登録日2003-04-10
公開日2003-04-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the vertebrate NADP(H)-dependent alcohol dehydrogenase (ADH8)
J.Mol.Biol., 330, 2003
1P1G
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MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) WITH PRO-1 MUTATED TO GLY-1
分子名称: PROTEIN (MACROPHAGE MIGRATION INHIBITORY FACTOR)
著者Lubetsky, J.B, Lolis, E.
登録日1999-03-24
公開日1999-06-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity.
Biochemistry, 38, 1999
1OWF
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Crystal structure of a mutant IHF (BetaE44A) complexed with the native H' Site
分子名称: 5'-D(*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*TP*GP*CP*AP*CP*C)-3', 5'-D(*GP*GP*CP*CP*AP*AP*AP*AP*AP*AP*GP*CP*AP*TP*T)-3', Integration Host Factor Alpha-subunit, ...
著者Lynch, T.W, Read, E.K, Mattis, A.N, Gardner, J.F, Rice, P.A.
登録日2003-03-28
公開日2003-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Integration Host Factor: putting a twist on protein-DNA recognition
J.Mol.Biol., 330, 2003
1OYO
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Regulation of protease activity by melanin: Crystal structure of the complex formed between proteinase K and melanin monomers at 2.0 resolution
分子名称: 3H-INDOLE-5,6-DIOL, CALCIUM ION, Proteinase K
著者Singh, N, Sharma, S, Kumar, S, Raman, G, Singh, T.P.
登録日2003-04-06
公開日2003-05-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Regulation of protease activity by melanin: Crystal structure of the complex formed between proteinase K and melanin monomers at 2.0 resolution
To be Published
1P1U
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Crystal structure of the GluR2 ligand-binding core (S1S2J) L650T mutant in complex with AMPA (ammonium sulfate crystal form)
分子名称: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2, SULFATE ION
著者Armstrong, N, Mayer, M.L, Gouaux, E.
登録日2003-04-14
公開日2003-06-10
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1OJO
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SPECIFICITY AND MECHANISM OF STREPTOCOCCUS PNEUMONIAE HYALURONATE LYASE: COMPLEX OF THE TYR408PHE MUTANT WITH 4-SULPHATED CHONDROITIN DISACCHARIDE
分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, HYALURONATE LYASE, SULFATE ION
著者Rigden, D.J, Jedrzejas, M.J.
登録日2003-07-11
公開日2003-10-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of Streptococcus Pneumoniae Hyaluronate Lyase in Complex with Chondroitin and Chondroitin Sulfate Disaccharides: Insights Into Specificity and Mechanism of Action
J.Biol.Chem., 278, 2003
1P5Y
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The structures of host range controlling regions of the capsids of canine and feline parvoviruses and mutants
分子名称: Coat protein VP2
著者Agbandje-McKenna, M, Govindasamy, L.
登録日2003-04-28
公開日2003-08-26
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of host range-controlling regions of the capsids of canine and feline parvoviruses and mutants.
J.Virol., 77, 2003
1P6K
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Rat neuronal NOS D597N mutant heme domain with L-N(omega)-nitroarginine-2,4-L-diaminobutyric amide bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, D-MANNITOL, ...
著者Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.-M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
登録日2003-04-29
公開日2004-01-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
Nat.Struct.Mol.Biol., 11, 2004
1ORU
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Crystal Structure of APC1665, YUAD protein from Bacillus subtilis
分子名称: CHLORIDE ION, SULFATE ION, yuaD protein
著者Kim, Y, Joachimiak, A, Edwards, A, Skarina, T, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
登録日2003-03-15
公開日2003-09-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of APC1665, YUAD protein from Bacillus subtilis
To be Published
1OSA
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CRYSTAL STRUCTURE OF RECOMBINANT PARAMECIUM TETRAURELIA CALMODULIN AT 1.68 ANGSTROMS RESOLUTION
分子名称: CALCIUM ION, CALMODULIN
著者Sundaralingam, M.
登録日1993-08-11
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structure of the recombinant Paramecium tetraurelia calmodulin at 1.68 A resolution.
Acta Crystallogr.,Sect.D, 50, 1994
1P92
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Crystal Structure of (H79A)DtxR
分子名称: BETA-MERCAPTOETHANOL, Diphtheria toxin repressor
著者D'Aquino, J.A, Ringe, D.
登録日2003-05-08
公開日2004-05-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Determinants of the SRC homology domain 3-like fold.
J.Bacteriol., 185, 2003
1OM1
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Crystal structure of maize CK2 alpha in complex with IQA
分子名称: (5-OXO-5,6-DIHYDRO-INDOLO[1,2-A]QUINAZOLIN-7-YL)-ACETIC ACID, Casein kinase II, alpha chain
著者Battistutta, R, De Moliner, E, Zanotti, G.
登録日2003-02-24
公開日2004-02-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).
Biochem.J., 374, 2003
1PAF
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THE 2.5 ANGSTROMS STRUCTURE OF POKEWEED ANTIVIRAL PROTEIN
分子名称: POKEWEED ANTIVIRAL PROTEIN
著者Monzingo, A.F, Collins, E.J, Ernst, S.R, Irvin, J.D, Robertus, J.D.
登録日1992-10-19
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The 2.5 A structure of pokeweed antiviral protein.
J.Mol.Biol., 233, 1993
1OOY
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SUCCINYL-COA:3-KETOACID COA TRANSFERASE FROM PIG HEART
分子名称: PHOSPHATE ION, POTASSIUM ION, Succinyl-CoA:3-ketoacid-coenzyme A transferase, ...
著者Coros, A.M, Swenson, L, Wolodko, W.T, Fraser, M.E.
登録日2003-03-04
公開日2004-04-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the CoA transferase from pig heart to 1.7 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
1OPR
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THE CRYSTAL STRUCTURE OF THE OROTATE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH OROTATE AND ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, OROTATE PHOSPHORIBOSYLTRANSFERASE, ...
著者Scapin, G, Sacchettini, J.C.
登録日1995-01-06
公開日1996-01-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of the orotate phosphoribosyltransferase complexed with orotate and alpha-D-5-phosphoribosyl-1-pyrophosphate.
Biochemistry, 34, 1995
1OWG
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Crystal structure of WT IHF complexed with an altered H' site (T44A)
分子名称: 5'-D(*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*AP*GP*CP*AP*CP*C)-3', 5'-D(*GP*GP*CP*CP*AP*AP*AP*AP*AP*AP*GP*CP*AP*TP*T)-3', Integration Host Factor Alpha-subunit, ...
著者Lynch, T.W, Read, E.K, Mattis, A.N, Gardner, J.F, Rice, P.A.
登録日2003-03-28
公開日2003-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Integration Host Factor: putting a twist on protein-DNA recognition
J.Mol.Biol., 330, 2003
1OSU
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STRUCTURE OF THE RNA HEXAMER, R(UUCGCG), WITH A 5'-UU-OVERHANG EXHIBITING HOOGSTEEN-LIKE TRANS U-U BASE PAIRS
分子名称: RNA (5'-R(*UP*UP*CP*GP*CP*G)-3')
著者Wahl, M.C, Rao, S.T, Sundaralingam, M.
登録日1995-11-08
公開日1996-04-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The structure of r(UUCGCG) has a 5'-UU-overhang exhibiting Hoogsteen-like trans U.U base pairs.
Nat.Struct.Biol., 3, 1996
1OY1
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X-Ray Structure Of ElbB From E. Coli. Northeast Structural Genomics Research Consortium (Nesg) Target Er105
分子名称: PUTATIVE sigma cross-reacting protein 27A
著者Benach, J, Edstrom, W, Ma, L.C, Xiao, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2003-04-03
公開日2003-04-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献X-Ray Structure Of ElbB From E. Coli. Northeast Structural Genomics Research Consortium (Nesg) Target Er105
To be Published
1OSV
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STRUCTURAL BASIS FOR BILE ACID BINDING AND ACTIVATION OF THE NUCLEAR RECEPTOR FXR
分子名称: 6-ETHYL-CHENODEOXYCHOLIC ACID, Bile acid receptor, Nuclear receptor coactivator 2
著者Mi, L.Z, Devarakonda, S, Harp, J.M, Han, Q, Pellicciari, R, Willson, T.M, Khorasanizadeh, S, Rastinejad, F.
登録日2003-03-20
公開日2004-03-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
1OYQ
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TRYPSIN INHIBITOR COMPLEX
分子名称: CALCIUM ION, SULFATE ION, Trypsin, ...
著者Nar, H.
登録日2003-04-07
公開日2003-04-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for Inhibition Promiscuity of Dual Specific Thrombin and Factor Xa Blood Coagulation Inhibitors
Structure, 9, 2001

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