1QRW
 
 | | CRYSTAL STRUCTURE OF AN ALPHA-LYTIC PROTEASE MUTANT WITH ACCELERATED FOLDING KINETICS, R102H/G134S, PH 8 | | 分子名称: | ALHPA-LYTIC PROTEASE, GLYCEROL, SULFATE ION | | 著者 | Derman, A.I, Mau, T, Agard, D.A. | | 登録日 | 1999-06-16 | | 公開日 | 1999-06-18 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | A Genetic Screen That Targets Specifically the Folding Transition State of Alpha-Lytic Protease
To be Published, 1999
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1OLN
 | | Model for thiostrepton antibiotic binding to L11 substrate from 50S ribosomal RNA | | 分子名称: | 50S RIBOSOMAL PROTEIN L11, RNA, THIOSTREPTON | | 著者 | Lentzen, G, Klinck, R, Matassova, N, Aboul-Ela, F, Murchie, A.I.H. | | 登録日 | 2003-08-08 | | 公開日 | 2003-09-11 | | 最終更新日 | 2019-08-21 | | 実験手法 | SOLUTION NMR, THEORETICAL MODEL | | 主引用文献 | Structural Basis for Contrasting Activities of Ribosome Binding Thiazole Antibiotics
Chem.Biol., 10, 2003
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3URC
 | | T181G mutant of alpha-Lytic Protease | | 分子名称: | Alpha-lytic protease, GLYCEROL, SULFATE ION | | 著者 | Kelch, B.A, Agard, D.A. | | 登録日 | 2011-11-22 | | 公開日 | 2012-05-23 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Functional modulation of a protein folding landscape via side-chain distortion.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3URE
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1AZF
 | | CHICKEN EGG WHITE LYSOZYME CRYSTAL GROWN IN BROMIDE SOLUTION | | 分子名称: | BROMIDE ION, LYSOZYME | | 著者 | Lim, K, Nadarajah, A, Forsythe, E.L, Pusey, M.L. | | 登録日 | 1997-11-17 | | 公開日 | 1998-02-25 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Locations of bromide ions in tetragonal lysozyme crystals.
Acta Crystallogr.,Sect.D, 54, 1998
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3G0F
 | | KIT kinase domain mutant D816H in complex with sunitinib | | 分子名称: | Mast/stem cell growth factor receptor, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, SULFATE ION | | 著者 | Gajiwala, K.S, Wu, J.C, Lunney, E.A, Demetri, G.D. | | 登録日 | 2009-01-27 | | 公開日 | 2009-02-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients.
Proc.Natl.Acad.Sci.USA, 106, 2009
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1QQ4
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1QRK
 | | HUMAN FACTOR XIII WITH STRONTIUM BOUND IN THE ION SITE | | 分子名称: | PROTEIN (COAGULATION FACTOR XIII), STRONTIUM ION | | 著者 | Fox, B.A, Yee, V.C, Pederson, L.C, Le Trong, I, Bishop, P.D, Stenkamp, R.E, Teller, D.C. | | 登録日 | 1999-06-14 | | 公開日 | 1999-07-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Identification of the calcium binding site and a novel ytterbium site in blood coagulation factor XIII by x-ray crystallography.
J.Biol.Chem., 274, 1999
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487D
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3URD
 | | T181A mutant of alpha-Lytic Protease | | 分子名称: | Alpha-lytic protease, GLYCEROL, SULFATE ION | | 著者 | Kelch, B.A, Agard, D.A. | | 登録日 | 2011-11-22 | | 公開日 | 2012-05-23 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | Functional modulation of a protein folding landscape via side-chain distortion.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4APE
 | | THE ACTIVE SITE OF ASPARTIC PROTEINASES | | 分子名称: | ENDOTHIAPEPSIN | | 著者 | Pearl, L.H, Sewell, B.T, Jenkins, J.A, Cooper, J.B, Blundell, T.L. | | 登録日 | 1986-06-09 | | 公開日 | 1986-07-14 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984
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4PRO
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4AMX
 | | CRYSTAL STRUCTURE OF THE GRACILARIOPSIS LEMANEIFORMIS ALPHA-1,4- GLUCAN LYASE Covalent Intermediate Complex with 5-fluoro-glucosyl- fluoride | | 分子名称: | 5-fluoro-beta-D-glucopyranose, ALPHA-1,4-GLUCAN LYASE ISOZYME 1, GLYCEROL, ... | | 著者 | Rozeboom, H.J, Yu, S, Madrid, S, Kalk, K.H, Dijkstra, B.W. | | 登録日 | 2012-03-14 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of Alpha-1,4-Glucan Lyase, a Unique Glycoside Hydrolase Family Member with a Novel Catalytic Mechanism.
J.Biol.Chem., 288, 2013
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3G0E
 | | KIT kinase domain in complex with sunitinib | | 分子名称: | Mast/stem cell growth factor receptor, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | | 著者 | Gajiwala, K.S, Wu, J.C, Lunney, E.A, Gemetri, G.D. | | 登録日 | 2009-01-27 | | 公開日 | 2009-02-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients.
Proc.Natl.Acad.Sci.USA, 106, 2009
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1BHC
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3QNW
 | | Caspase-6 in complex with Z-VAD-FMK inhibitor | | 分子名称: | Caspase-6, Z-VAD-FMK | | 著者 | Mueller, I, Lamers, M, Ritchie, A, Park, H, Dominguez, C, Munoz, I, Maillard, M, Kiselyov, A. | | 登録日 | 2011-02-09 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structure of human caspase-6 in complex with Z-VAD-FMK: New peptide binding mode observed for the non-canonical caspase conformation.
Bioorg.Med.Chem.Lett., 21, 2011
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1NBB
 | | N-BUTYLISOCYANIDE BOUND RHODOBACTER CAPSULATUS CYTOCHROME C' | | 分子名称: | CYTOCHROME C', N-BUTYL ISOCYANIDE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Tahirov, T.H, Misaki, S, Meyer, T.E, Cusanovich, M.A, Higuchi, Y, Yasuoka, N. | | 登録日 | 1996-03-18 | | 公開日 | 1996-08-17 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Concerted movement of side chains in the haem vicinity observed on ligand binding in cytochrome c' from rhodobacter capsulatus.
Nat.Struct.Biol., 3, 1996
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1P09
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3TVJ
 | | Catalytic fragment of MASP-2 in complex with its specific inhibitor developed by directed evolution on SGCI scaffold | | 分子名称: | Mannan-binding lectin serine protease 2 A chain, Mannan-binding lectin serine protease 2 B chain, Protease inhibitor SGPI-2, ... | | 著者 | Heja, D, Harmat, V, Dobo, J, Szasz, R, Kekesi, K.A, Zavodszky, P, Gal, P, Pal, G. | | 登録日 | 2011-09-20 | | 公開日 | 2012-04-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2.
J.Biol.Chem., 287, 2012
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1QRX
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3BBA
 | | Structure of active wild-type Prevotella intermedia interpain A cysteine protease | | 分子名称: | interpain A | | 著者 | Mallorqui-Fernandez, N, Manandhar, S.P, Mallorqui-Fernandez, G, Uson, I, Wawrzonek, K, Kantyka, T, Sola, M, Thogersen, I.B, Enghild, J.J, Potempa, J, Gomis-Ruth, F.X. | | 登録日 | 2007-11-09 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | A New Autocatalytic Activation Mechanism for Cysteine Proteases Revealed by Prevotella intermedia Interpain A
J.Biol.Chem., 283, 2008
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2A40
 | | Ternary complex of the WH2 domain of WAVE with Actin-DNAse I | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Chereau, D, Kerff, F, Dominguez, R. | | 登録日 | 2005-06-27 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A3Z
 | | Ternary complex of the WH2 domain of WASP with Actin-DNAse I | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Chereau, D, Kerff, F, Dominguez, R. | | 登録日 | 2005-06-27 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.078 Å) | | 主引用文献 | Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
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3BB7
 | | Structure of Prevotella intermedia prointerpain A fragment 39-359 (mutant C154A) | | 分子名称: | interpain A | | 著者 | Mallorqui-Fernandez, N, Manandhar, S.P, Mallorqui-Fernandez, G, Uson, I, Wawrzonek, K, Kantyka, T, Sola, M, Thogersen, I.B, Enghild, J.J, Potempa, J, Gomis-Ruth, F.X. | | 登録日 | 2007-11-09 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A New Autocatalytic Activation Mechanism for Cysteine Proteases Revealed by Prevotella intermedia Interpain A
J.Biol.Chem., 283, 2008
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2A42
 | | Actin-DNAse I Complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Chereau, D, Kerff, F, Dominguez, R. | | 登録日 | 2005-06-27 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
Proc.Natl.Acad.Sci.Usa, 102, 2005
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