PDB: 5591 件ウェブページステータス検索Chemie searchBIRD

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7T6H	E. coli dihydroorotate dehydrogenase 分子名称: Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, OROTIC ACID 著者 Horwitz, S.M, Ambarian, J.A, Davis, K.M. 登録日 2021-12-13 公開日 2022-03-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. Rsc Chem Biol, 3, 2022
7T5Y	E. coli dihydroorotate dehydrogenase bound to the inhibitor HMNQ 分子名称: 3-methyl-2-[(2E)-non-2-en-1-yl]quinolin-4(1H)-one, Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, ... 著者 Horwitz, S.M, Ambarian, J.A, Davis, K.M. 登録日 2021-12-13 公開日 2022-03-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. Rsc Chem Biol, 3, 2022
5OWJ	The dynamic dimer structure of the chaperone Trigger Factor (conformer 2) 分子名称: Trigger factor 著者 Morgado, L, Burmann, B.M, Sharpe, T, Mazur, A, Hiller, S. 登録日 2017-09-01 公開日 2017-11-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The dynamic dimer structure of the chaperone Trigger Factor. Nat Commun, 8, 2017
1RAE	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
1RAF	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
1RAD	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
1RAG	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
1Q95	Aspartate Transcarbamylase (ATCase) of Escherichia coli: A New Crystalline R State Bound to PALA, or to Product Analogues Phosphate and Citrate 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... 著者 Huang, J, Lipscomb, W.N. 登録日 2003-08-22 公開日 2004-06-08 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Aspartate Transcarbamylase (ATCase) of Escherichia coli: A New Crystalline R-State Bound to PALA, or to Product Analogues Citrate and Phosphate Biochemistry, 43, 2004
1RAC	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
1SKU	E. coli Aspartate Transcarbamylase 240's Loop Mutant (K244N) 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, MALONATE ION, ... 著者 Alam, N, Stieglitz, K.A, Caban, M.D, Gourinath, S, Tsuruta, H, Kantrowitz, E.R. 登録日 2004-03-05 公開日 2004-03-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 240s Loop Interactions Stabilize the T State of Escherichia coli Aspartate Transcarbamoylase. J.Biol.Chem., 279, 2004
1RAH	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
1RAB	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
1RAI	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
1RAA	CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. 登録日 1992-08-14 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
1T36	Crystal structure of E. coli carbamoyl phosphate synthetase small subunit mutant C248D complexed with uridine 5'-monophosphate 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Carbamoyl-phosphate synthase large chain, ... 著者 Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. 登録日 2004-04-24 公開日 2004-09-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Long-range allosteric transitions in carbamoyl phosphate synthetase. Protein Sci., 13, 2004
1TU0	Aspartate Transcarbamoylase Catalytic Chain Mutant E50A Complex with Phosphonoacetamide 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, PHOSPHONOACETAMIDE, ... 著者 Stieglitz, K, Stec, B, Baker, D.P, Kantrowitz, E.R. 登録日 2004-06-23 公開日 2004-07-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Monitoring the Transition from the T to the R State in E.coli Aspartate Transcarbamoylase by X-ray Crystallography: Crystal Structures of the E50A Mutant Enzyme in Four Distinct Allosteric States. J.Mol.Biol., 341, 2004
1TTH	Aspartate Transcarbamoylase Catalytic Chain Mutant Glu50Ala Complexed with N-(Phosphonacetyl-L-Aspartate) (PALA) 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... 著者 Stieglitz, K, Stec, B, Baker, D.P, Kantrowitz, E.R. 登録日 2004-06-22 公開日 2004-07-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Monitoring the Transition from the T to the R State in E.coli Aspartate Transcarbamoylase by X-ray Crystallography: Crystal Structures of the E50A Mutant Enzyme in Four Distinct Allosteric States. J.Mol.Biol., 341, 2004
4EEI	Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase, ... 著者 Maltseva, N, Kim, Y, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-03-28 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.921 Å) 主引用文献 Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate To be Published
4E2F	Crystal Structure of E. coli Aspartate Transcarbamoylase K164E/E239K Mutant in an intermediate state 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION 著者 Guo, W, Kantrowitz, E.R. 登録日 2012-03-08 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Trapping and structure determination of an intermediate in the allosteric transition of aspartate transcarbamoylase. Proc.Natl.Acad.Sci.USA, 109, 2012
7AM9	OMPD-domain of human UMPS in complex with the substrate OMP at 0.99 Angstroms resolution 分子名称: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, SULFATE ION, ... 著者 Tittmann, K, Rindfleisch, S, Krull, M. 登録日 2020-10-08 公開日 2021-11-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (0.99 Å) 主引用文献 Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5-monophosphate decarboxylase catalysis Nat Catal, 5, 2022
4DF1	Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus complexed with inhibitor BMP 分子名称: 6-HYDROXYURIDINE-5'-PHOSPHATE, NICKEL (II) ION, Orotidine 5'-phosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. 登録日 2012-01-22 公開日 2013-01-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.899 Å) 主引用文献 Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus complexed with inhibitor BMP To be Published
4FYY	E. coli Aspartate Transcarbamoylase Complexed with CTP, UTP, and Mg2+ 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Cockrell, G.M, Kantrowitz, E.R. 登録日 2012-07-05 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9395 Å) 主引用文献 Metal Ion Involvement in the Allosteric Mechanism of Escherichia coli Aspartate Transcarbamoylase. Biochemistry, 51, 2012
4DBE	Crystal structure of orotidine 5'-monophosphate decarboxylase from Sulfolobus solfataricus complexed with inhibitor BMP 分子名称: 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase, ... 著者 Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. 登録日 2012-01-14 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.789 Å) 主引用文献 Crystal structure of orotidine 5'-monophosphate decarboxylase from Sulfolobus solfataricus complexed with inhibitor BMP To be Published
4DBD	Crystal structure of orotidine 5'-monophosphate decarboxylase from Sulfolobus solfataricus 分子名称: Orotidine 5'-phosphate decarboxylase, SULFATE ION 著者 Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. 登録日 2012-01-14 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Crystal structure of orotidine 5'-monophosphate decarboxylase from Sulfolobus solfataricus To be Published
7AT1	CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ... 著者 Gouaux, J.E, Stevens, R.C, Lipscomb, W.N. 登録日 1989-09-22 公開日 1990-10-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH. Biochemistry, 29, 1990

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