PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

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1FUB	FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA 分子名称: CHLORIDE ION, INSULIN, A CHAIN, ... 著者 Von Dreele, R.B, Stephens, P.W, Blessing, R.H, Smith, G.D. 登録日 2000-09-14 公開日 2000-10-16 最終更新日 2018-10-03 実験手法 POWDER DIFFRACTION 主引用文献 The first protein crystal structure determined from high-resolution X-ray powder diffraction data: a variant of T3R3 human insulin-zinc complex produced by grinding. Acta Crystallogr.,Sect.D, 56, 2000
1FWT	AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP, E4P AND CADMIUM 分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, CADMIUM ION, ERYTHOSE-4-PHOSPHATE, ... 著者 Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. 登録日 2000-09-24 公開日 2001-04-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
5OWD	Vitamin D receptor complex 分子名称: (1~{S},3~{Z})-3-[(2~{E})-2-[(1~{S},3~{a}~{S},7~{a}~{S})-7~{a}-methyl-1-[(2~{S})-6-methyl-2-oxidanyl-hept-5-en-2-yl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol, Nuclear receptor coactivator 1, Vitamin D3 receptor A 著者 Rochel, N, Li, W. 登録日 2017-08-31 公開日 2018-02-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Investigation of 20S-hydroxyvitamin D3 analogs and their 1 alpha-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities. Sci Rep, 8, 2018
1MQR	THE CRYSTAL STRUCTURE OF ALPHA-D-GLUCURONIDASE (E386Q) FROM BACILLUS STEAROTHERMOPHILUS T-6 分子名称: ALPHA-D-GLUCURONIDASE, GLYCEROL 著者 Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. 登録日 2002-09-17 公開日 2003-09-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of Geobacillus stearothermophilus {alpha}-Glucuronidase Complexed with Its Substrate and Products: MECHANISTIC IMPLICATIONS. J.Biol.Chem., 279, 2004
3B29	Human leukotriene C4 synthase in complex with dodecyl-beta-D-selenomaltoside 分子名称: GLUTATHIONE, Leukotriene C4 synthase, SULFATE ION, ... 著者 Saino, H, Ago, H, Miyano, M. 登録日 2011-07-22 公開日 2011-12-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Seleno-detergent MAD phasing of leukotriene C4 synthase in complex with dodecyl-beta-D-selenomaltoside Acta Crystallogr.,Sect.F, 67, 2011
2Y3R	Structure of the tirandamycin-bound FAD-dependent tirandamycin oxidase TamL in P21 space group 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Carlson, J.C, Li, S, Gunatilleke, S.S, Anzai, Y, Burr, D.A, Podust, L.M, Sherman, D.H. 登録日 2010-12-22 公開日 2011-06-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes Nat.Chem, 3, 2011
7LSA	Ruminococcus bromii Amy12 with maltoheptaose 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Koropatkin, N.M, Cockburn, D.W, Brown, H.A, Kibler, R.D. 登録日 2021-02-18 公開日 2021-07-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structure and substrate recognition by the Ruminococcus bromii amylosome pullulanases. J.Struct.Biol., 213, 2021
2Y60	Isopenicillin N synthase with AC-D-methionine 分子名称: FE (III) ION, GLYCEROL, ISOPENICILLIN N SYNTHASE, ... 著者 Rutledge, P.J, Clifton, I.J, Ge, W. 登録日 2011-01-19 公開日 2012-02-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The Crystal Structure of Isopenicillin N Synthase with Delta((L)-Alpha-Aminoadipoyl)-(L)-Cysteinyl-(D)-Methionine Reveals Thioether Coordination to Iron. Arch.Biochem.Biophys., 516, 2011
2FG8	Structure of Human Ferritin L Chain 分子名称: CESIUM ION, Ferritin light chain 著者 Wang, Z.M, Li, C, Ellenburg, M.P, Ruble, J.R, Ho, J.X, Carter, D.C. 登録日 2005-12-21 公開日 2006-07-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of human ferritin L chain. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
4NZ4	Structure of Vibrio cholerae chitin de-N-acetylase in complex with 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE (NDG) and zinc ion 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, ACETATE ION, CALCIUM ION, ... 著者 Albesa-Jove, D, Andres, E, Biarnes, X, Planas, A, Guerin, M.E. 登録日 2013-12-11 公開日 2014-08-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.944 Å) 主引用文献 Structural basis of chitin oligosaccharide deacetylation. Angew.Chem.Int.Ed.Engl., 53, 2014
2FCM	X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin with a Cubic Space Group 分子名称: ACETATE ION, CADMIUM ION, Ubiquitin 著者 Bang, D, Gribenko, A.V, Tereshko, V, Kossiakoff, A.A, Kent, S.B, Makhatadze, G.I. 登録日 2005-12-12 公開日 2006-01-31 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis. Nat.Chem.Biol., 2, 2006
2ZTV	The binary complex of D-3-hydroxybutyrate dehydrogenase with NAD+ 分子名称: D(-)-3-hydroxybutyrate dehydrogenase, GLYCEROL, MAGNESIUM ION, ... 著者 Nakashima, K, Nakajima, Y, Ito, K, Yoshimoto, T. 登録日 2008-10-09 公開日 2009-08-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor. J.Biochem., 145, 2009
3IEQ	Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytidine 分子名称: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-07-23 公開日 2009-08-04 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011
5O54	Glycogen Phosphorylase b in complex with 29a 分子名称: (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(5-phenyl-4~{H}-1,2,4-triazol-3-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ... 著者 Kyriakis, E, Solovou, T.G.A, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D. 登録日 2017-05-31 公開日 2017-09-27 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. J. Med. Chem., 60, 2017
1G7Z	NMR SOLUTION STRUCTURE OF D(CGCTAGCG)2 分子名称: 5'-D(*CP*GP*CP*TP*AP*GP*CP*G)-3' 著者 Isaacs, R.J, Spielmann, H.P. 登録日 2000-11-15 公開日 2001-03-28 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Relationship of DNA structure to internal dynamics: correlation of helical parameters from NOE-based NMR solution structures of d(GCGTACGC)(2) and d(CGCTAGCG)(2) with (13)C order parameters implies conformational coupling in dinucleotide units. J.Mol.Biol., 307, 2001
3QNC	Crystal Structure of a Rationally Designed OXA-10 Variant Showing Carbapenemase Activity, OXA-10loop48 分子名称: 1,2-ETHANEDIOL, CARBON DIOXIDE, Oxacillinase, ... 著者 De Luca, F, Benvenuti, M, Carboni, F, Pozzi, C, Rossolini, G.M, Mangani, S, Docquier, J.D. 登録日 2011-02-08 公開日 2011-11-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D {beta}-lactamase OXA-10 by rational protein design. Proc.Natl.Acad.Sci.USA, 108, 2011
7JKS	Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2411a in complex with HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 core, The heavy chain of antibody 2411a, ... 著者 Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R. 登録日 2020-07-28 公開日 2021-06-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth. Immunity, 54, 2021
3PAE	Crystal structure of the K84D mutant of OXA-24/40 in complex with doripenem 分子名称: (4R,5S)-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, SULFATE ION 著者 Powers, R.A, Leonard, D.A, Schneider, K.D. 登録日 2010-10-19 公開日 2011-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of the Class D Carbapenemase OXA-24 from Acinetobacter baumannii in Complex with Doripenem. J.Mol.Biol., 406, 2011
1WQ2	Neutron Crystal Structure Of Dissimilatory Sulfite Reductase D (DsrD) 分子名称: Protein dsvD, SULFATE ION 著者 Chatake, T, Mizuno, N, Voordouw, G, Higuchi, Y, Arai, S, Tanaka, I, Niimura, N. 登録日 2004-09-19 公開日 2005-09-19 最終更新日 2023-10-25 実験手法 NEUTRON DIFFRACTION (2.4 Å) 主引用文献 Crystallization and preliminary neutron analysis of the dissimilatory sulfite reductase D (DsrD) protein from the sulfate-reducing bacterium Desulfovibrio vulgaris. Acta Crystallogr.,Sect.D, 59, 2003
5CGO	Structure of quasiracemic Ala-Magainin 2 with a beta amino acid substitution at position 13 分子名称: ACPC-13 derivative of Ala-Magainin 2, D-Ala-Magainin 2 著者 Hayouka, Z, Thomas, N.C, Mortenson, D.E, Satyshur, K.A, Weisblum, B, Forest, K.T, Gellman, S.H. 登録日 2015-07-09 公開日 2015-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif. J.Am.Chem.Soc., 137, 2015
5OW9	Vitamin D receptor complex 分子名称: (1~{S},3~{Z})-3-[(2~{E})-2-[(1~{S},3~{a}~{S},7~{a}~{S})-7~{a}-methyl-1-[(2~{S})-6-methyl-2-oxidanyl-heptan-2-yl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol, Nuclear receptor coactivator 1, Vitamin D3 receptor A 著者 Rochel, N, Li, W. 登録日 2017-08-31 公開日 2018-02-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 Investigation of 20S-hydroxyvitamin D3 analogs and their 1 alpha-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities. Sci Rep, 8, 2018
5OWZ	Glycogen Phosphorylase in complex with KS172 分子名称: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-[4-(trifluoromethyl)phenyl]-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... 著者 Kyriakis, E, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S.M, Leonidas, D.D. 登録日 2017-09-05 公開日 2018-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Bioorg. Chem., 77, 2018
3A40	Crystal structure of the human VDR ligand binding domain bound to the synthetic agonist compound 2alpha-methyl-AMCR277B(C23R) 分子名称: (1S,2S,3R,5Z,7E,14beta,17alpha,23R)-23-(2-hydroxy-2-methylpropyl)-2-methyl-20,24-epoxy-9,10-secochola-5,7,10-triene-1,3-diol, SULFATE ION, Vitamin D3 receptor 著者 Sato, Y, Antony, P, Huet, T, Sigueiro, R, Rochel, N, Moras, D, Structural Proteomics in Europe 2 (SPINE-2) 登録日 2009-06-25 公開日 2010-02-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure-function relationships and crystal structures of the vitamin D receptor bound 2 alpha-methyl-(20S,23S)- and 2 alpha-methyl-(20S,23R)-epoxymethano-1 alpha,25-dihydroxyvitamin D3 J.Med.Chem., 53, 2010
4JMN	Crystal structure of LD transpeptidase LdtMt1 from M. tuberculosis 分子名称: Probable L,D-transpeptidase LdtA 著者 Ruggiero, A, Correale, S, Berisio, R. 登録日 2013-03-14 公開日 2013-10-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of free and inhibited forms of the L,D-transpeptidase LdtMt1 from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 69, 2013
5O50	Glycogen Phosphorylase b in complex with 33a 分子名称: (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-phenyl-1~{H}-imidazol-2-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ... 著者 Kantsadi, A.L, Kyriakis, E, Stravodimos, G.A, Solovou, T.G.A, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D. 登録日 2017-05-31 公開日 2017-09-27 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. J. Med. Chem., 60, 2017

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