PDB: 48062 件ウェブページステータス検索Chemie searchBIRD

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8HIG	Co-crystal structure of C-terminal DNA binding domain of Saccharopolyspora erythraea GlnR in complex with its cognate promoter DNA 分子名称: DNA (5'-D(*AP*CP*GP*TP*AP*AP*CP*AP*TP*CP*GP*CP*GP*GP*TP*AP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*TP*AP*CP*CP*GP*CP*GP*AP*TP*GP*TP*TP*AP*CP*GP*T)-3'), DNA-binding response OmpR family regulator 著者 Lin, W, Xu, J.C, Zhang, Y. 登録日 2022-11-20 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.329 Å) 主引用文献 Co-crystal structure of C-terminal DNA binding domain of Saccharopolyspora erythraea GlnR in complex with its cognate promoter DNA To Be Published
8HM5	Epoxide hydrolase from Caballeronia sordidicola PAMC 26510 分子名称: Epoxide hydrolase 著者 Hwang, J, Lee, M.J, Do, H, Lee, J.H. 登録日 2022-12-02 公開日 2023-12-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Structural insights into the distinct substrate preferences of two bacterial epoxide hydrolases. Int.J.Biol.Macromol., 264, 2024
8HM3	Complex of PPIase-BfUbb 分子名称: GLYCEROL, MAGNESIUM ION, Peptidylprolyl isomerase, ... 著者 Xu, J.H, Chen, Z, Gao, X. 登録日 2022-12-02 公開日 2023-11-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Bacteroides fragilis ubiquitin homologue drives intraspecies bacterial competition in the gut microbiome. Nat Microbiol, 9, 2024
8HRP	Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Corynebacterium glutamicum ATCC13032 in complex with NAD and G3P 分子名称: 1,2-ETHANEDIOL, GLYCERALDEHYDE-3-PHOSPHATE, GLYCEROL, ... 著者 Son, H.F, Kim, K.J. 登録日 2022-12-15 公開日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structure-Guided Protein Engineering of Glyceraldehyde-3-phosphate Dehydrogenase from Corynebacterium glutamicum for Dual NAD/NADP Cofactor Specificity. J.Agric.Food Chem., 71, 2023
8HOM	Crystal Structure of SARS-CoV-2 Omicron Main Protease (Mpro) in Complex with Ensitrelvir 分子名称: 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione 著者 Lin, M, Liu, X. 登録日 2022-12-10 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Crystal Structure of SARS-CoV-2 Omicron Main Protease (Mpro) in Complex with Ensitrelvir To Be Published
8HKI	Human TRiC open state 分子名称: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... 著者 Cong, Y, Liu, C.X. 登録日 2022-11-27 公開日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Pathway and mechanism of tubulin folding mediated by TRiC/CCT conjugated with its ATPase cycle revealed by cryo-EM To Be Published
8HQ2	Crystal structure of human ADAM22 in complex with human LGI1 mutant 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ... 著者 Liu, H, Lin, Z, Xu, F. 登録日 2022-12-13 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Crystal structure of human ADAM22 in complex with human LGI1 mutant To Be Published
8HPY	Crystal structure of human LGI1-ADAM22 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ... 著者 Liu, H, Xu, F. 登録日 2022-12-13 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (5.87 Å) 主引用文献 Crystal structure of human LGI1-ADAM22 complex To Be Published
8HQ1	Crystal Structure Of Human Lgi1-Adam22 Complex In Space Group C2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ... 著者 Liu, H.L, Lin, Z.H, Xu, F. 登録日 2022-12-13 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (4.17 Å) 主引用文献 Structure Of Human Lgi1-Adam22 Complex In Space Group C2 To Be Published
8HPP	Crystal structure of human INTS3 with SAGE1 分子名称: Integrator complex subunit 3, Sarcoma antigen 1 著者 Deng, W, Wu, J, Lei, M. 登録日 2022-12-12 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Cancer-testis antigen SAGE1 is a pan-cancer master regulator of RNA polymerase II To Be Published
2VDY	Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN 著者 Zhou, A, Wei, Z, Read, R.J. 登録日 2007-10-13 公開日 2008-05-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release. J.Mol.Biol., 380, 2008
5I5K	Structure of complement C5 in complex with eculizumab 分子名称: Complement C5, Eculizumab heavy chain (variable domain), Eculizumab light chain (variable domain), ... 著者 Schatz-Jakobsen, J.A, Andersen, G.R. 登録日 2016-02-15 公開日 2016-03-16 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structural Basis for Eculizumab-Mediated Inhibition of the Complement Terminal Pathway. J Immunol., 197, 2016
5IB4	Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR and Nickel 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B. 登録日 2016-02-22 公開日 2017-02-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype. J.Biol.Chem., 2019
5IBF	Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 19a 分子名称: 4-(3'-amino[1,1'-biphenyl]-3-yl)-1H-pyrazol-5-amine, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C. 登録日 2016-02-22 公開日 2016-04-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors. J.Med.Chem., 59, 2016
5IGV	Macrolide 2'-phosphotransferase type II - complex with GDP and azithromycin 分子名称: AZITHROMYCIN, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Berghuis, A.M, Fong, D.H. 登録日 2016-02-28 公開日 2017-04-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure, 25, 2017
5IM5	Crystal structure of designed two-component self-assembling icosahedral cage I53-40 分子名称: Designed Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase, Designed Riboflavin synthase 著者 Liu, Y.A, Cascio, D, Sawaya, M.R, Bale, J.B, Collazo, M.J, Thomas, C, Sheffler, W, King, N.P, Baker, D, Yeates, T.O. 登録日 2016-03-05 公開日 2016-07-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.699 Å) 主引用文献 Accurate design of megadalton-scale two-component icosahedral protein complexes. Science, 353, 2016
5I03	tRNA-guanine Transglycosylase (TGT) in co-crystallized complex with 6-Amino-4-[2-(4-methylphenyl)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one 分子名称: 1,2-ETHANEDIOL, 6-AMINO-4-[2-(4-METHYLPHENYL)ETHYL]-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, GLYCEROL, ... 著者 Ehrmann, F.R, Heine, A, Klebe, G. 登録日 2016-02-03 公開日 2017-02-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Co-crystallization, Isothermal titration calorimetry and nanoESI-MS reveal dimer disturbing inhibitors To be Published
5IJ7	Structure of Hs/AcPRC2 in complex with a pyridone inhibitor 分子名称: 5,8-dichloro-2-[(4-ethyl-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-7-({1-[(2R)-2-hydroxypropanoyl]piperidin-4-yl}oxy)-3,4-dihydroisoquinolin-1(2H)-one, Enhancer of Zeste Homolog 2 (EZH2),Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, ... 著者 Gajiwala, K.S, Brooun, A, Deng, Y.-L, Liu, W. 登録日 2016-03-01 公開日 2016-05-04 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance. Nat Commun, 7, 2016
5I29	TAF1(2) bound to a pyrrolopyridone compound 分子名称: CALCIUM ION, N,N-dimethyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide, Transcription initiation factor TFIID subunit 1 著者 Tang, Y, Poy, F, Bellon, S.F. 登録日 2016-02-08 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains. J.Med.Chem., 59, 2016
5IKQ	The Structure of Meclofenamic Acid Bound to Human Cyclooxygenase-2 分子名称: 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACRYLIC ACID, ... 著者 Orlando, B.J, Malkowski, M.G. 登録日 2016-03-03 公開日 2016-05-25 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Substrate-selective Inhibition of Cyclooxygeanse-2 by Fenamic Acid Derivatives Is Dependent on Peroxide Tone. J.Biol.Chem., 291, 2016
5I7D	Crystal Structure of srGAP2 F-BARx WT Form-2 分子名称: SLIT-ROBO Rho GTPase-activating protein 2 著者 Sporny, M, Guez-Haddad, J, Isupov, M.N, Opatowsky, Y. 登録日 2016-02-17 公開日 2017-08-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.95 Å) 主引用文献 Structural Basis for srGAP2 Membrane Interactions, and Antagonism by the Human Specific Paralog srGAP2C To Be Published
5I7S	Crystal structure of B. pseudomallei FabI in complex with NAD and PT01 分子名称: 5-ETHYL-2-PHENOXYPHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Hirschbeck, M.W, Eltschkner, S, Tonge, P.J, Kisker, C. 登録日 2016-02-18 公開日 2017-02-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.595 Å) 主引用文献 Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase. Biochemistry, 56, 2017
5IIO	Crystal structure of the DNA polymerase lambda binary complex 分子名称: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*(8OG)P*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(P*GP*CP*CP*G)-3'), ... 著者 Burak, M.J, Guja, K.E, Garcia-Diaz, M. 登録日 2016-03-01 公開日 2016-08-17 最終更新日 2016-09-28 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 A fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dG. Embo J., 35, 2016
5ILX	Crystal structure of Ribosome inactivating protein from Momordica balsamina with Uracil at 1.70 Angstrom resolution 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ribosome inactivating protein, ... 著者 Singh, P.K, Singh, A, Pandey, S, Kaur, P, Sharma, S, Singh, T.P. 登録日 2016-03-05 公開日 2016-03-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of Ribosome inactivating protein from Momordica balsamina with Uracil at 1.70 Angstrom resolution To Be Published
5I50	Structure of OmoMYC bound to double-stranded DNA 分子名称: DNA (5'-D(P*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*CP*TP*AP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*CP*GP*GP*GP*TP*G)-3'), Myc proto-oncogene protein 著者 Koelmel, W, Jung, L.A, Kuper, J, Eilers, M, Kisker, C. 登録日 2016-02-13 公開日 2016-10-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors. Oncogene, 36, 2017

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