1ANX
 
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1BCY
 | | RECOMBINANT RAT ANNEXIN V, T72K MUTANT | | 分子名称: | ANNEXIN V, CALCIUM ION, SULFATE ION | | 著者 | Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. | | 登録日 | 1998-05-04 | | 公開日 | 1998-11-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components.
Biochemistry, 37, 1998
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1BCK
 | | HUMAN CYCLOPHILIN A COMPLEXED WITH 2-THR CYCLOSPORIN | | 分子名称: | CYCLOSPORIN C, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A | | 著者 | Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D. | | 登録日 | 1998-04-30 | | 公開日 | 1998-09-16 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A.
J.Mol.Biol., 283, 1998
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1XPA
 | | SOLUTION STRUCTURE OF THE DNA-AND RPA-BINDING DOMAIN OF THE HUMAN REPAIR FACTOR XPA, NMR, 1 STRUCTURE | | 分子名称: | XPA, ZINC ION | | 著者 | Ikegami, T, Kuraoka, I, Saijo, M, Kodo, N, Kyogoku, Y, Morikawa, K, Tanaka, K, Shirakawa, M. | | 登録日 | 1998-07-06 | | 公開日 | 1999-07-22 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA.
Nat.Struct.Biol., 5, 1998
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5UWW
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1BC0
 | | RECOMBINANT RAT ANNEXIN V, W185A MUTANT | | 分子名称: | ANNEXIN V, CALCIUM ION, SULFATE ION | | 著者 | Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. | | 登録日 | 1998-05-04 | | 公開日 | 1998-11-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components.
Biochemistry, 37, 1998
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1AWV
 | | CYPA COMPLEXED WITH HVGPIA | | 分子名称: | CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN | | 著者 | Vajdos, F.F. | | 登録日 | 1997-10-05 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
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5VTB
 | | Crystal structure of RBBP4 bound to BCL11a peptide | | 分子名称: | B-cell lymphoma/leukemia 11A, GLYCEROL, Histone-binding protein RBBP4 | | 著者 | Meagher, J.L, Stuckey, J.A. | | 登録日 | 2017-05-16 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes.
J. Biol. Chem., 293, 2018
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5TI5
 | | CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH INHIBITOR 8841880 | | 分子名称: | 1,2-ETHANEDIOL, 3-bromo-N-[3-(2-oxo-2,3-dihydro-1H-pyrrol-1-yl)phenyl]benzene-1-sulfonamide, Bromodomain-containing protein 4 | | 著者 | Zhu, J.-Y, Ember, S.W.J, Schonbrunn, E. | | 登録日 | 2016-10-01 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations.
ACS Omega, 2, 2017
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5TI6
 | | CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH INHIBITOR 8841881 | | 分子名称: | 1,2-ETHANEDIOL, 2,6-difluoro-N-[3-(2-oxopyrrolidin-1-yl)phenyl]benzene-1-sulfonamide, Bromodomain-containing protein 4 | | 著者 | Zhu, J.-Y, Ember, S.W.J, Schonbrunn, E. | | 登録日 | 2016-10-01 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.704 Å) | | 主引用文献 | Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations.
ACS Omega, 2, 2017
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5TI4
 | | CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH INHIBITOR 8841871 | | 分子名称: | 1,2-ETHANEDIOL, 3-chloro-4-fluoro-N-[3-(2-oxopyrrolidin-1-yl)phenyl]benzene-1-sulfonamide, Bromodomain-containing protein 4 | | 著者 | Zhu, J.-Y, Ember, S.W.J, SCHONBRUNN, E. | | 登録日 | 2016-09-30 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations.
ACS Omega, 2, 2017
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1Z00
 | | Solution structure of the C-terminal domain of ERCC1 complexed with the C-terminal domain of XPF | | 分子名称: | DNA excision repair protein ERCC-1, DNA repair endonuclease XPF | | 著者 | Tripsianes, K, Folkers, G, Ab, E, Das, D, Odijk, H, Jaspers, N.G.J, Hoeijmakers, J.H.J, Kaptein, R, Boelens, R. | | 登録日 | 2005-03-01 | | 公開日 | 2005-12-20 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Structure of the Human ERCC1/XPF Interaction Domains Reveals a Complementary Role for the Two Proteins in Nucleotide Excision Repair
Structure, 13, 2005
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1ZAI
 | | Fructose-1,6-bisphosphate Schiff base intermediate in FBP aldolase from rabbit muscle | | 分子名称: | 1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM), Fructose-bisphosphate aldolase A | | 著者 | St-Jean, M, Lafrance-Vanasse, J, Liotard, B, Sygusch, J. | | 登録日 | 2005-04-06 | | 公開日 | 2005-05-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | High Resolution Reaction Intermediates of Rabbit Muscle Fructose-1,6-bisphosphate Aldolase: substrate cleavage and induced fit.
J.Biol.Chem., 280, 2005
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5T9W
 | | Discovery of a Potent Cyclophilin Inhibitor (Compound 5) based on Structural Simplification of Sanglifehrin A | | 分子名称: | 3-[(3-hydroxyphenyl)methyl]-6-(propan-2-yl)-19-oxa-1,4,7,25-tetraazabicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetrone, Peptidyl-prolyl cis-trans isomerase A | | 著者 | Appleby, T.C, Steadman, V, Pettit, P, Schmitz, U, Mackman, R.L, Schultz, B. | | 登録日 | 2016-09-09 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A.
J. Med. Chem., 60, 2017
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1Z7G
 | | Free human HGPRT | | 分子名称: | Hypoxanthine-guanine phosphoribosyltransferase | | 著者 | Keough, D.T, Brereton, I.M, de Jersey, J, Guddat, L.W. | | 登録日 | 2005-03-24 | | 公開日 | 2005-08-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Crystal Structure of Free Human Hypoxanthine-guanine Phosphoribosyltransferase Reveals Extensive Conformational Plasticity Throughout the Catalytic Cycle
J.Mol.Biol., 351, 2005
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1DOA
 | | Structure of the rho family gtp-binding protein cdc42 in complex with the multifunctional regulator rhogdi | | 分子名称: | GERAN-8-YL GERAN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Hoffman, G.R, Nassar, N, Cerione, R.C. | | 登録日 | 1999-12-20 | | 公開日 | 2000-02-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI.
Cell(Cambridge,Mass.), 100, 2000
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1ZAJ
 | | Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with mannitol-1,6-bisphosphate, a competitive inhibitor | | 分子名称: | D-MANNITOL-1,6-DIPHOSPHATE, Fructose-bisphosphate aldolase A | | 著者 | St-Jean, M, Lafrance-Vanasse, J, Liotard, B, Sygusch, J. | | 登録日 | 2005-04-06 | | 公開日 | 2005-05-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | High Resolution Reaction Intermediates of Rabbit Muscle Fructose-1,6-bisphosphate Aldolase: substrate cleavage and induced fit.
J.Biol.Chem., 280, 2005
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5VOM
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2AD9
 | | Solution structure of Polypyrimidine Tract Binding protein RBD1 complexed with CUCUCU RNA | | 分子名称: | 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 | | 著者 | Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T. | | 登録日 | 2005-07-20 | | 公開日 | 2005-10-04 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of PTB bound to RNA: specific binding and implications for splicing regulation
Science, 309, 2005
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1E32
 | | Structure of the N-Terminal domain and the D1 AAA domain of membrane fusion ATPase p97 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, P97 | | 著者 | Zhang, X, Shaw, A, Bates, P.A, Gorman, M.A, Kondo, H, Dokurno, P, Leonard M, G, Sternberg, J.E, Freemont, P.S. | | 登録日 | 2000-06-05 | | 公開日 | 2001-05-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the Aaa ATPase P97
Mol.Cell, 6, 2000
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1DT9
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1ZAL
 | | Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with partially disordered tagatose-1,6-bisphosphate, a weak competitive inhibitor | | 分子名称: | Fructose-bisphosphate aldolase A, PHOSPHATE ION | | 著者 | St-Jean, M, Lafrance-Vanasse, J, Liotard, B, Sygusch, J. | | 登録日 | 2005-04-06 | | 公開日 | 2005-05-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | High Resolution Reaction Intermediates of Rabbit Muscle Fructose-1,6-bisphosphate Aldolase: substrate cleavage and induced fit.
J.Biol.Chem., 280, 2005
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1B64
 | | SOLUTION STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR DOMAIN FROM HUMAN ELONGATION FACTOR-ONE BETA, NMR, 20 STRUCTURES | | 分子名称: | ELONGATION FACTOR 1-BETA | | 著者 | Perez, J.M.J, Siegal, G, Kriek, J, Hard, K, Dijk, J, Canters, G.W, Moller, W. | | 登録日 | 1999-01-20 | | 公開日 | 1999-05-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the guanine nucleotide exchange domain of human elongation factor 1beta reveals a striking resemblance to that of EF-Ts from Escherichia coli.
Structure Fold.Des., 7, 1999
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1ZKK
 | | Crystal structure of hSET8 in ternary complex with H4 peptide (16-24) and AdoHcy | | 分子名称: | Histone-lysine N-methyltransferase, H4 lysine-20 specific, Peptide corresponding to residues 15-24 of histone H4, ... | | 著者 | Couture, J.-F, Collazo, E, Brunzelle, J.S, Trievel, R.C. | | 登録日 | 2005-05-03 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase
Genes Dev., 19, 2005
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1BFS
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