PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

---

8HI1	Streptococcus thermophilus Cas1-Cas2- prespacer ternary complex 分子名称: CRISPR-associated endonuclease Cas1, DNA (26-MER), DNA (31-MER), ... 著者 Chen, Q, Luo, Y. 登録日 2022-11-18 公開日 2023-09-13 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 DnaQ mediates directional spacer acquisition in the CRISPR-Cas system by a time-dependent mechanism. Innovation (N Y), 4, 2023
1GVE	Aflatoxin aldehyde reductase (AKR7A1) from Rat Liver 分子名称: AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3, CITRIC ACID, GLYCEROL, ... 著者 Kozma, E, Brown, E, Ellis, E.M, Lapthorn, A.J. 登録日 2002-02-08 公開日 2002-06-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 The Crystal Structure of Rat Liver Akr7A1: A Dimeric Member of the Aldo-Keto Reductase Superfamily J.Biol.Chem., 277, 2002
3AV1	The human nucleosome structure containing the histone variant H3.2 分子名称: 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Tachiwana, H, Osakabe, A, Shiga, T, Miya, Y, Kimura, H, Kagawa, W, Kurumizaka, H. 登録日 2011-02-18 公開日 2011-06-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of human nucleosomes containing major histone H3 variants Acta Crystallogr.,Sect.D, 67, 2011
2IEO	Crystal structure analysis of HIV-1 protease mutant I84V with a potent non-peptide inhibitor (UIC-94017) 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, Protease, ... 著者 Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Manna, D, Hussain, A.K, Leshchenko, S, Ghosh, A.K, Louis, J.M, Harrison, R.W, Weber, I.T. 登録日 2006-09-19 公開日 2006-10-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 High Resolution Crystal Structures of HIV-1 Protease with a Potent Non-Peptide Inhibitor (Uic-94017) Active Against Multi-Drug-Resistant Clinical Strains. J.Mol.Biol., 338, 2004
1H5M	X-ray induced reduction of horseradish peroxidase C1A Compound III (0-100% dose) 分子名称: ACETATE ION, CALCIUM ION, HYDROGEN PEROXIDE, ... 著者 Berglund, G.I, Carlsson, G.H, Hajdu, J, Smith, A.T, Szoke, H, Henriksen, A. 登録日 2001-05-22 公開日 2002-05-27 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The Catalytic Pathway of Horseradish Peroxidase at High Resolution Nature, 417, 2002
1T7Q	Crystal structure of the F565A mutant of murine carnitine acetyltransferase in complex with carnitine and CoA 分子名称: 1,2-ETHANEDIOL, CARNITINE, COENZYME A, ... 著者 Hsiao, Y.-S, Jogl, G, Tong, L. 登録日 2004-05-10 公開日 2004-06-22 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase J.Biol.Chem., 279, 2004
3P4V	Human carbonic anhydrase II in complex with (+)-Xylariamide A 分子名称: 3-chloro-N-[(2E)-4-methoxy-4-oxobut-2-enoyl]-L-tyrosine, Carbonic anhydrase 2, ZINC ION 著者 Hofmann, A, Nankervis, T, Davis, R. 登録日 2010-10-07 公開日 2011-04-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Natural Product-Based Phenols as Novel Probes for Mycobacterial and Fungal Carbonic Anhydrases. J.Med.Chem., 54, 2011
1H6Q	Translationally Controlled Tumor-associated Protein p23fyp from Schizosaccharomyces pombe 分子名称: TRANSLATIONALLY CONTROLLED TUMOR PROTEIN 著者 Thaw, P, Baxter, N.J, Sedelnikova, S.E, Price, C, Waltho, J.P, Craven, C.J. 登録日 2001-06-20 公開日 2001-08-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones. Nat. Struct. Biol., 8, 2001
3AV2	The human nucleosome structure containing the histone variant H3.3 分子名称: 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Tachiwana, H, Osakabe, A, Shiga, T, Miya, M, Kimura, H, Kagawa, W, Kurumizaka, H. 登録日 2011-02-18 公開日 2011-06-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of human nucleosomes containing major histone H3 variants Acta Crystallogr.,Sect.D, 67, 2011
1O4B	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU83876. 分子名称: N-ACETYL-N-[1-(1,1'-BIPHENYL-4-YLMETHYL)-2-OXOAZEPAN-3-YL]-3,4-DIPHOSPHONOPHENYLALANINAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
6ZWM	cryo-EM structure of human mTOR complex 2, overall refinement 分子名称: ACETYL GROUP, INOSITOL HEXAKISPHOSPHATE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Scaiola, A, Mangia, F, Imseng, S, Boehringer, D, Ban, N, Maier, T. 登録日 2020-07-28 公開日 2020-11-18 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The 3.2- angstrom resolution structure of human mTORC2. Sci Adv, 6, 2020
1O42	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU81843. 分子名称: N-ACETYL-N-[1-(1,1'-BIPHENYL-4-YLMETHYL)-2-OXOAZEPAN-3-YL]-O-PHOSPHONOTYROSINAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4E	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78299. 分子名称: 2,6-DIFORMYL-4-METHYLPHENYL DIHYDROGEN PHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4R	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78783. 分子名称: (PHENYL-PHOSPHONO-METHYL)-PHOSPHONIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1T7N	Crystal structure of the M564G mutant of murine CrAT 分子名称: Carnitine acetyltransferase 著者 Hsiao, Y.-S, Jogl, G, Tong, L. 登録日 2004-05-10 公開日 2004-06-22 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase J.Biol.Chem., 279, 2004
8C4I	Ligand-free Crystal Structure of the decameric Sulfofructose Transaldolase BmSF-TAL 分子名称: BmSF-TAL 著者 Snow, A.J.D, Sharma, M, Davies, G.J. 登録日 2023-01-04 公開日 2023-02-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure and mechanism of sulfofructose transaldolase, a key enzyme in sulfoquinovose metabolism. Structure, 31, 2023
8C7H	Cryo-EM Map of the latTGF-beta 28G11 Fab complex 分子名称: 28G11 Fab heavy chain, 28G11 Fab light chain, Transforming growth factor beta activator LRRC32, ... 著者 Ebenhoch, R, Nar, H. 登録日 2023-01-16 公開日 2023-03-01 最終更新日 2023-03-29 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Anti-GARP Antibodies Inhibit Release of TGF-beta by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro. Immunohorizons, 7, 2023
6ZYA	Extended human uromodulin filament core at 3.5 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Stanisich, J.J, Zyla, D, Afanasyev, P, Xu, J, Pilhofer, M, Boeringer, D, Glockshuber, R. 登録日 2020-07-31 公開日 2020-09-02 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism. Elife, 9, 2020
3AZG	Crystal Structure of Human Nucleosome Core Particle Containing H3K115Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
3AYW	Crystal Structure of Human Nucleosome Core Particle Containing H3K56Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-19 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
3AZI	Crystal Structure of Human Nucleosome Core Particle Containing H4K31Q mutation 分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... 著者 Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. 登録日 2011-05-25 公開日 2011-09-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains Biochemistry, 50, 2011
1VJ3	STRUCTURAL STUDIES ON BIO-ACTIVE COMPOUNDS. CRYSTAL STRUCTURE AND MOLECULAR MODELING STUDIES ON THE PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COFACTOR COMPLEX WITH TAB, A HIGHLY SELECTIVE ANTIFOLATE. 分子名称: ACETIC ACID N-[2-CHLORO-5-[6-ETHYL-2,4-DIAMINO-PYRIMID-5-YL]-PHENYL]-[BENZYL-TRIAZEN-3-YL]ETHYL ESTER, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V, Galitsky, N, Rak, D, Luft, J.R, Queener, S.F, Laughton, C.A, Malcolm, F.G. 登録日 2004-01-13 公開日 2004-01-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural studies on bioactive compounds. 30. Crystal structure and molecular modeling studies on the Pneumocystis carinii dihydrofolate reductase cofactor complex with TAB, a highly selective antifolate. Biochemistry, 39, 2000
6AMR	Solution NMR structure of a putative thioredoxin (ECH_0218) in the reduced state from Ehrlichia chaffeensis, the etiological agent responsible for human monocytic ehrlichiosis. Seattle Structural Genomics Center for Infectious Disease target EhchA.00546.a 分子名称: Thioredoxin 著者 Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-08-11 公開日 2017-09-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR structures of oxidized and reduced Ehrlichia chaffeensis thioredoxin: NMR-invisible structure owing to backbone dynamics. Acta Crystallogr F Struct Biol Commun, 74, 2018
1CHH	STRUCTURAL STUDIES OF THE ROLES OF RESIDUES 82 AND 85 AT THE INTERACTIVE FACE OF CYTOCHROME C 分子名称: CYTOCHROME C, HEME C, SULFATE ION 著者 Lo, T.P, Brayer, G.D. 登録日 1994-06-01 公開日 1994-12-20 最終更新日 2021-03-03 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural studies of the roles of residues 82 and 85 at the interactive face of cytochrome c. Biochemistry, 34, 1995
1H7Y	Translationally Controlled Tumor-associated Protein p23fyp from Schizosaccharomyces pombe 分子名称: TRANSLATIONALLY CONTROLLED TUMOR PROTEIN 著者 Thaw, P, Baxter, N.J, Sedelnikova, S.E, Price, C, Waltho, J.P, Craven, C.J. 登録日 2001-01-19 公開日 2001-08-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones. Nat. Struct. Biol., 8, 2001

<858859860861862863864865866867868869870871872873>