PDB: 42545 件ウェブページステータス検索Chemie searchBIRD

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9KNT	ERDRP-0519-bound measles virus L-P complex 分子名称: 2-methyl-~{N}-[4-[(2~{S})-2-(2-morpholin-4-ylethyl)piperidin-1-yl]sulfonylphenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide, Phosphoprotein, RNA-directed RNA polymerase L, ... 著者 Wang, Y.R, Zhang, H.Q. 登録日 2024-11-19 公開日 2025-07-16 最終更新日 2025-07-23 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structures of the measles virus polymerase complex with non-nucleoside inhibitors and mechanism of inhibition. Cell, 2025
9KNZ	ERDRP-0519-bound Nipah virus L-P complex 分子名称: 2-methyl-~{N}-[4-[(2~{S})-2-(2-morpholin-4-ylethyl)piperidin-1-yl]sulfonylphenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide, Phosphoprotein, RNA-directed RNA polymerase L, ... 著者 Wang, Y.R, Zhang, H.Q. 登録日 2024-11-19 公開日 2025-07-16 最終更新日 2025-07-23 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures of the measles virus polymerase complex with non-nucleoside inhibitors and mechanism of inhibition. Cell, 2025
9KNV	AS-136A-bound measles virus L-P complex 分子名称: 2-methyl-~{N}-(4-piperidin-1-ylsulfonylphenyl)-5-(trifluoromethyl)pyrazole-3-carboxamide, Phosphoprotein, RNA-directed RNA polymerase L, ... 著者 Wang, Y.R, Zhang, H.Q. 登録日 2024-11-19 公開日 2025-07-16 最終更新日 2025-07-23 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structures of the measles virus polymerase complex with non-nucleoside inhibitors and mechanism of inhibition. Cell, 2025
5DTU	Crystal structure of the RNA-helicase Prp28 from Chaetomium thermophilum bound to ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Prp28 著者 Tauchert, M.J, Ficner, R. 登録日 2015-09-18 公開日 2016-05-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.199 Å) 主引用文献 Structural analysis of the spliceosomal RNA helicase Prp28 from the thermophilic eukaryote Chaetomium thermophilum. Acta Crystallogr.,Sect.F, 72, 2016
5F2I	Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes Glu163Gln mutant 分子名称: ACETATE ION, CALCIUM ION, GLYCEROL, ... 著者 LowKam, C. 登録日 2015-12-01 公開日 2016-12-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 NON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE To Be Published
5F2L	Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes in complex with competitive inhibitor talitol-1,6-bisphosphate 分子名称: ACETATE ION, CALCIUM ION, CHLORIDE ION, ... 著者 LowKam, C. 登録日 2015-12-02 公開日 2016-12-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.755 Å) 主引用文献 NON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE To Be Published
5F4S	Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes in complex with FBP 分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, 1,6-di-O-phosphono-D-fructose, CALCIUM ION, ... 著者 LowKam, C. 登録日 2015-12-03 公開日 2016-12-28 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.724 Å) 主引用文献 NON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE To Be Published
5F2G	Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes Glu164Gln mutant in complex with FBP 分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, 1,6-di-O-phosphono-D-fructose, CALCIUM ION, ... 著者 LowKam, C. 登録日 2015-12-01 公開日 2016-12-07 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.918 Å) 主引用文献 NON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE To Be Published
5F4W	Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes in complex with TBP 分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, 1,6-di-O-phosphono-D-tagatose, CALCIUM ION, ... 著者 LowKam, C. 登録日 2015-12-03 公開日 2017-02-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.663 Å) 主引用文献 NON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE To Be Published
5FF7	Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes in complex with DHAP and G3P 分子名称: CALCIUM ION, GLYCERALDEHYDE-3-PHOSPHATE, SN-GLYCEROL-3-PHOSPHATE, ... 著者 Low-Kam, C, Liotard, B. 登録日 2015-12-18 公開日 2017-02-15 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.092 Å) 主引用文献 NON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE To Be Published
5F2M	Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes in complex with competitive inhibitor hexitol-1,6-bisphosphate 分子名称: CALCIUM ION, D-MANNITOL-1,6-DIPHOSPHATE, Tagatose 1,6-diphosphate aldolase 2 著者 LowKam, C. 登録日 2015-12-02 公開日 2016-12-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 NON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE To Be Published
5HHK	Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P21 space group (Se-MET) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ... 著者 Zhao, C, Pyle, A.M. 登録日 2016-01-11 公開日 2016-05-04 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution. Nat.Struct.Mol.Biol., 23, 2016
3K9B	Crystal structure of human liver carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Cyclosarin (GF) 分子名称: Liver carboxylesterase 1, cyclohexyl (S)-methylphosphonofluoridoate 著者 Hemmert, A.C, Redinbo, M.R. 登録日 2009-10-15 公開日 2010-01-19 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin. Mol.Pharmacol., 77, 2010
8BC9	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 24 分子名称: 1,2-ETHANEDIOL, N-hydroxybenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... 著者 Vester, K, Loll, B, Wahl, M.C. 登録日 2022-10-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
8BCF	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 78 分子名称: 1,2-ETHANEDIOL, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... 著者 Vester, K, Loll, B, Wahl, M.C. 登録日 2022-10-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
8BCC	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 39 分子名称: 1,2-ETHANEDIOL, 3-oxidanylbenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... 著者 Vester, K, Loll, B, Wahl, M.C. 登録日 2022-10-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
8BCA	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 26 分子名称: 1,2-ETHANEDIOL, 3-azanyl-~{N}-methyl-4-(methylamino)benzenesulfonamide, GLYCEROL, ... 著者 Vester, K, Loll, B, Wahl, M.C. 登録日 2022-10-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
8BCE	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 76 分子名称: 1,2-ETHANEDIOL, N-methoxybenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... 著者 Vester, K, Loll, B, Wahl, M.C. 登録日 2022-10-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
8BCG	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 86 分子名称: 1,2-ETHANEDIOL, 4-chloranyl-~{N}-methoxy-~{N}-methyl-benzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... 著者 Vester, K, Loll, B, Wahl, M.C. 登録日 2022-10-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
8BCD	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 50 分子名称: Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, phenylsulfonylcarbamodithioic acid 著者 Vester, K, Loll, B, Wahl, M.C. 登録日 2022-10-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
8BCB	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 34 分子名称: 1,2-ETHANEDIOL, Pre-mRNA-processing-splicing factor 8, SULFANILAMIDE, ... 著者 Vester, K, Loll, B, Wahl, M.C. 登録日 2022-10-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
8BC8	Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 18 分子名称: 1,2-ETHANEDIOL, 3-azanyl-4-oxidanyl-benzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... 著者 Vester, K, Loll, B, Wahl, M.C. 登録日 2022-10-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
8UX1	Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle 分子名称: 153-bp Widom 601 DNA forward strand, 153-bp Widom 601 DNA reverse strand, GTP-binding nuclear protein Ran, ... 著者 Huang, S.K, Rubinstein, J.L, Kay, L.E. 登録日 2023-11-08 公開日 2023-11-22 最終更新日 2025-05-28 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle To Be Published
5E7P	Crystal Structure of MSMEG_0858 (Uniprot A0QQS4), a AAA ATPase. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein Cdc48, GLYCEROL, ... 著者 Unciulac-Carp, M, Smith, P, Shuman, S. 登録日 2015-10-12 公開日 2016-08-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.507 Å) 主引用文献 Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase (Msm0858). J.Bacteriol., 198, 2016
6DU5	Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 6 分子名称: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase, hp6-RNA (25-MER) 著者 Doxtader, K, Wang, P, Nam, Y. 登録日 2018-06-19 公開日 2018-09-26 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.006 Å) 主引用文献 Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor. Mol. Cell, 71, 2018

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