PDB: 31489 件ウェブページステータス検索Chemie searchBIRD

---

5IJL	D-family DNA polymerase - DP2 subunit (catalytic subunit) 分子名称: DNA polymerase II large subunit, ZINC ION 著者 Sauguet, L, Raia, P, De Larue, M. 登録日 2016-03-02 公開日 2016-08-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography. Nat Commun, 7, 2016
6UCT	Crystal structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (C-arm deletion mutant) 分子名称: p9-1 著者 Llauger, G, Klinke, S, Monti, D, Sycz, G, Cerutti, M.L, Goldbaum, F.A, del Vas, M, Otero, L.H. 登録日 2019-09-17 公開日 2021-03-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.47 Å) 主引用文献 Crystal structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (C-arm deletion mutant) To Be Published
5IK2	Caldalaklibacillus thermarum F1-ATPase (epsilon mutant) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP synthase epsilon chain, ATP synthase gamma chain, ... 著者 Ferguson, S.A, Cook, G.M, Montgomery, M.G, Leslie, A.G.W, Walker, J.E. 登録日 2016-03-03 公開日 2016-09-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Regulation of the thermoalkaliphilic F1-ATPase from Caldalkalibacillus thermarum. Proc.Natl.Acad.Sci.USA, 113, 2016
8PA3	Crystal structure of the metallo-beta-lactamase VIM1 with 2500 分子名称: 7-[(1~{S})-1-[4-(2-azanylethyl)phenoxy]ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION 著者 Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J. 登録日 2023-06-07 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Crystal structure of the metallo-beta-lactamase VIM1 with 2500 To Be Published
6Q8M	GH10 endo-xylanase 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase, ... 著者 Davies, G.J, Rowland, R.J, Wu, L, Moroz, O, Blagova, E. 登録日 2018-12-15 公開日 2019-06-05 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Dynamic and Functional Profiling of Xylan-Degrading Enzymes inAspergillusSecretomes Using Activity-Based Probes. Acs Cent.Sci., 5, 2019
5TR0	Lipoxygenase-1 (soybean) L754A mutant at 293K 分子名称: FE (II) ION, Seed linoleate 13S-lipoxygenase-1 著者 Poss, E.M, Fraser, J.S. 登録日 2016-10-24 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network. J.Am.Chem.Soc., 141, 2019
6Q92	Crystal structure of human Arginase-1 at pH 7.0 in complex with ABH 分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION, ... 著者 Grobben, Y, Uitdehaag, J.C.M, Zaman, G.J.R. 登録日 2018-12-17 公開日 2019-12-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158. J Struct Biol X, 4, 2020
6LZ2	Crystal structure of a thermostable green fluorescent protein (TGP) with a synthetic nanobody (Sb44) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ... 著者 Cai, H, Yao, H, Li, T, Hutter, C, Tang, Y, Li, Y, Seeger, M, Li, D. 登録日 2020-02-17 公開日 2020-12-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 An improved fluorescent tag and its nanobodies for membrane protein expression, stability assay, and purification. Commun Biol, 3, 2020
8PAH	Crystal structure of the metallo-beta-lactamase VIM1 with 2596 分子名称: 7-[(1~{S})-1-[[4-(aminomethyl)phenyl]methoxy]ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION 著者 Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J. 登録日 2023-06-07 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Crystal structure of the metallo-beta-lactamase VIM1 with 2596 To Be Published
5TSA	Crystal structure of the Zrt-/Irt-like protein from Bordetella bronchiseptica with bound Zn2+ 分子名称: CADMIUM ION, Membrane protein, ZINC ION 著者 Zhang, T, Fellner, M, Sui, D, Liu, J, Hu, J. 登録日 2016-10-28 公開日 2017-09-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway. Sci Adv, 3, 2017
5LZH	Cholera toxin classical B-pentamer in complex with inhibitor PC262 分子名称: (2~{R},4~{S},5~{R},6~{R})-5-acetamido-2-[4-[3-[2-[(2~{S},3~{R},4~{R},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]ethylamino]-3-oxidanylidene-propyl]-1,2,3-triazol-1-yl]-4-oxidanyl-6-[(1~{R},2~{R})-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Heggelund, J.E, Martinsen, T, Krengel, U. 登録日 2016-09-29 公開日 2017-05-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics. Sci Rep, 7, 2017
7EA0	Crystal structure of human pyruvate dehydrogenase kinase 2 in complex with compound 1 分子名称: 1,3-dihydro-2H-indol-2-one, ACETATE ION, CHLORIDE ION, ... 著者 Orita, T, Doi, S, Iwanaga, T, Adachi, T. 登録日 2021-03-05 公開日 2021-08-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases. Bioorg.Med.Chem., 44, 2021
6XCB	Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with covalent inhibitor 20 分子名称: Botulinum neurotoxin type A, N-hydroxy-6-sulfanylhexanamide, ZINC ION 著者 Tararina, M.A, Allen, K.N. 登録日 2020-06-08 公開日 2020-09-23 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A. J.Med.Chem., 63, 2020
5ILY	Tobacco 5-epi-aristolochene synthase with BIS-TRIS buffer molecule and diphosphate (PPi) 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-epi-aristolochene synthase, DIPHOSPHATE, ... 著者 Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. 登録日 2016-03-05 公開日 2017-03-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme To Be Published
8PBW	Histidine-containing phosphotransfer protein from Chaetomium thermophilum 分子名称: 1,2-ETHANEDIOL, HPt domain-containing protein 著者 Paredes-Martinez, F, Casino, P. 登録日 2023-06-09 公開日 2024-07-03 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and functional insights underlying recognition of histidine phosphotransfer protein in fungal phosphorelay systems. Commun Biol, 7, 2024
5TTD	Minor pilin FctB from S. pyogenes with engineered intramolecular isopeptide bond 分子名称: FORMIC ACID, Maltose-binding periplasmic protein,Pilin isopeptide linkage domain protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Young, P.G, Kwon, H, Squire, C.J, Baker, E.N. 登録日 2016-11-02 公開日 2017-03-01 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Engineering a Lys-Asn isopeptide bond into an immunoglobulin-like protein domain enhances its stability. Sci Rep, 7, 2017
7EAS	Crystal structure of human pyruvate dehydrogenase kinase 2 in complex with compound 2 分子名称: 1H-pyrrolo[2,3-b]pyridine-3-carbonitrile, ACETATE ION, CHLORIDE ION, ... 著者 Orita, T, Doi, S, Iwanaga, T, Adachi, T. 登録日 2021-03-08 公開日 2021-08-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases. Bioorg.Med.Chem., 44, 2021
5DK1	S. erythraea trypsin mixed catalytic intermediate 分子名称: Trypsin 著者 Blankenship, E, Lodowski, D.T. 登録日 2015-09-02 公開日 2017-03-08 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (0.938 Å) 主引用文献 High resolution structures of S. erythraeus trypsin throughout the catalytic cycle To be Published
6UMA	Crystal structure of the TRIM7 B30.2 domain at 1.6 angstrom resolution 分子名称: E3 ubiquitin-protein ligase TRIM7, GLYCEROL, MALONATE ION 著者 Munoz Sosa, C.J, Carrizo, M.E. 登録日 2019-10-09 公開日 2021-04-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure and mutational analysis of the human TRIM7 B30.2 domain provide insights into the molecular basis of its binding to glycogenin-1. J.Biol.Chem., 296, 2021
5TPR	Desmethyl-4-deoxygadusol synthase from Anabaena variabilis (Ava_3858) with NAD+ and Zn2+ bound 分子名称: 3-dehydroquinate synthase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Kean, K.M, Karplus, P.A. 登録日 2016-10-21 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Evolution and Distribution of C7-Cyclitol Synthases in Prokaryotes and Eukaryotes. ACS Chem. Biol., 12, 2017
6XP3	Structure of human PYCR1 complexed with cyclopentanecarboxylic acid 分子名称: Pyrroline-5-carboxylate reductase 1, mitochondrial, SULFATE ION, ... 著者 Tanner, J.J, Bogner, A.N. 登録日 2020-07-07 公開日 2020-11-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1. J.Biol.Chem., 295, 2020
7EBH	Crystal structure of human pyruvate dehydrogenase kinase 2 in complex with compound 13 分子名称: 5-bromanyl-2-methyl-6-propyl-7H-pyrrolo[2,3-d]pyrimidine, ACETATE ION, CHLORIDE ION, ... 著者 Orita, T, Doi, S, Iwanaga, T, Adachi, T. 登録日 2021-03-09 公開日 2021-08-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases. Bioorg.Med.Chem., 44, 2021
8P96	TARGET COMPLEX 3 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, 1,2-Distearoyl-sn-glycerophosphoethanolamine, N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, ... 著者 Garau, G. 登録日 2023-06-05 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 TARGET COMPLEX 2 To Be Published
5M1Z	STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE ARB93A FROM FUSARIUM GRAMINEARUM IN COMPLEX WITH AN hydroximolactone INHIBITOR 分子名称: 1,2-ETHANEDIOL, Exo-1,5-alpha-L-arabinofuranobiosidase, GLYCEROL, ... 著者 Varrot, A. 登録日 2016-10-11 公開日 2016-12-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Exploiting sp(2) -Hybridisation in the Development of Potent 1,5-alpha-l-Arabinanase Inhibitors. Chembiochem, 18, 2017
8PA8	Crystal structure of the metallo-beta-lactamase VIM1 with 2551 分子名称: 7-[(1~{S})-1-[4-(3-azanylpropyl)-1,2,3-triazol-1-yl]ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION 著者 Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J. 登録日 2023-06-07 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Crystal structure of the metallo-beta-lactamase VIM1 with 2551 To Be Published

<811812813814815816817818819820821822823824825826>