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8JVQ
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Crystal structure of the dimeric RIFT fold protein Ph1_DG
分子名称: CITRIC ACID, Ph1_DG, SULFATE ION
著者Yagi, S, Tagami, S.
登録日2023-06-28
公開日2024-07-03
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献An ancestral fold reveals the evolutionary link between RNA polymerase and ribosomal proteins.
Nat Commun, 15, 2024
8JVO
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Crystal structure of the chemically synthesized mk2h_deltaMILPYS peptide homodimer, DZBB form
分子名称: SULFATE ION, mk2h_deltaMILPYS
著者Yagi, S, Tagami, S.
登録日2023-06-28
公開日2024-07-03
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献An ancestral fold reveals the evolutionary link between RNA polymerase and ribosomal proteins.
Nat Commun, 15, 2024
8JVR
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BU of 8jvr by Molmil
Crystal structure of the dimeric RIFT fold protein Ph1_GG
分子名称: ACETIC ACID, Ph1_GG, SULFATE ION
著者Yagi, S, Tagami, S.
登録日2023-06-28
公開日2024-07-03
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.794 Å)
主引用文献An ancestral fold reveals the evolutionary link between RNA polymerase and ribosomal proteins.
Nat Commun, 15, 2024
8JVX
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BU of 8jvx by Molmil
Crystal structure of the dimeric DZBB fold protein mkaL2_v1.2_Z
分子名称: mkaL2_v1.2_Z
著者Yagi, S, Tagami, S.
登録日2023-06-28
公開日2024-07-03
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献An ancestral fold reveals the evolutionary link between RNA polymerase and ribosomal proteins.
Nat Commun, 15, 2024
8JVW
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BU of 8jvw by Molmil
Crystal structure of the dimeric DZBB fold protein tkoL2_v1.2_Z
分子名称: GLYCINE, tkoL2_v1.2_Z
著者Yagi, S, Tagami, S.
登録日2023-06-28
公開日2024-07-03
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.806 Å)
主引用文献An ancestral fold reveals the evolutionary link between RNA polymerase and ribosomal proteins.
Nat Commun, 15, 2024
1R6K
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HPV11 E2 TAD crystal structure
分子名称: HPV11 REGULATORY PROTEIN E2
著者Wang, Y, Coulombe, R.
登録日2003-10-15
公開日2004-02-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the E2 Transactivation Domain of Human Papillomavirus Type 11 Bound to a Protein Interaction Inhibitor
J.Biol.Chem., 279, 2004
2ROX
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BU of 2rox by Molmil
TRANSTHYRETIN (ALSO CALLED PREALBUMIN) COMPLEX WITH THYROXINE (T4)
分子名称: 3,5,3',5'-TETRAIODO-L-THYRONINE, SULFATE ION, TRANSTHYRETIN
著者Wojtczak, A, Cody, V, Luft, J.R, Pangborn, W.
登録日1996-10-23
公開日1997-04-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of human transthyretin complexed with thyroxine at 2.0 A resolution and 3',5'-dinitro-N-acetyl-L-thyronine at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 52, 1996
6SUU
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BU of 6suu by Molmil
NMR structure of KRAS32R G9T conformer G-quadruplex within KRAS promoter region
分子名称: KRAS32R G9T, POTASSIUM ION
著者Marquevielle, J, Salgado, G.
登録日2019-09-16
公開日2020-02-05
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structure of two G-quadruplexes in equilibrium in the KRAS promoter.
Nucleic Acids Res., 48, 2020
1R6N
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HPV11 E2 TAD complex crystal structure
分子名称: 2-METHYL-PROPIONIC ACID, DIMETHYL SULFOXIDE, HPV11 REGULATORY PROTEIN E2, ...
著者Wang, Y, Coulombe, R.
登録日2003-10-15
公開日2004-02-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the E2 Transactivation Domain of Human Papillomavirus Type 11 Bound to a Protein Interaction Inhibitor
J.Biol.Chem., 279, 2004
6T51
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NMR structure of KRAS22RT G-quadruplex forming within KRAS promoter region at physological temperature
分子名称: KRAS22RT, POTASSIUM ION
著者Marquevielle, J, Salgado, G.
登録日2019-10-15
公開日2019-10-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H,13C, and15N chemical shift assignments of a G-quadruplex forming sequence within the KRAS proto-oncogene promoter region.
Biomol.Nmr Assign., 12, 2018
1N1N
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Structure of Mispairing of the Deoxycytosine with Deoxyadenosine 5' to the 8,9-Dihydro-8-(N7-guanyl)-9-Hydroxy-Aflatoxin B1 Adduct
分子名称: 5'-D(*AP*CP*AP*TP*CP*GP*AP*TP*CP*T)-3', 5'-D(*AP*GP*AP*TP*CP*AP*AP*TP*GP*T)-3', 8,9-DIHYDRO-9-HYDROXY-AFLATOXIN B1
著者Stone, M.P, Giri, I.
登録日2002-10-18
公開日2003-10-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Wobble dC.dA pairing 5' to the cationic guanine N7 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 adduct: implications for nontargeted AFB1 mutagenesis.
Biochemistry, 42, 2003
5AFW
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Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1, ...
著者Metzger, E, Willmann, D, McMillan, J, Petroll, K, Metzger, P, Gerhardt, S, vonMaessenhausen, A, Schott, A.K, Espejo, A, Eberlin, A, Wohlwend, D, Schuele, K.M, Schleicher, M, Perner, S, Bedford, M.T, Dengjel, J, Flaig, R, Einsle, O, Schuele, R.
登録日2015-01-26
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Assembly of Methylated Kdm1A and Chd1 Drives Androgen Receptor-Dependent Transcription and Translocation.
Nat.Struct.Mol.Biol., 23, 2016
7F6L
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BU of 7f6l by Molmil
Crystal structure of human MUS81-EME2 complex
分子名称: Crossover junction endonuclease MUS81, Probable crossover junction endonuclease EME2
著者Hua, Z.K, Zhang, D.P, Yuan, C, Lin, Z.H.
登録日2021-06-25
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the human MUS81-EME2 complex.
Structure, 30, 2022
7KBC
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BU of 7kbc by Molmil
The crystal structure of the 2009/H1N1/California PA endonuclease mutant E119D (construct with truncated loop 51-72) in complex with baloxavir acid
分子名称: Baloxavir acid, GLYCEROL, Hexa Vinylpyrrolidone K15, ...
著者Cuypers, M.G, Kumar, G, Slavish, J, White, S.W.
登録日2020-10-02
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism.
Nucleic Acids Res., 49, 2021
7KAF
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BU of 7kaf by Molmil
The crystal structure of the 2009/H1N1/California PA endonuclease I38T (construct with truncated loop 51-72) in complex with baloxavir acid
分子名称: Baloxavir acid, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ...
著者Cuypers, M.G, Kumar, G, Slavish, J, White, S.W.
登録日2020-09-30
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism.
Nucleic Acids Res., 49, 2021
1NVR
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BU of 1nvr by Molmil
The Complex Structure Of Checkpoint Kinase Chk1/Staurosporine
分子名称: Peptide ASVSA, STAUROSPORINE, SULFATE ION, ...
著者Zhao, B, Bower, M.J, McDevitt, P.J, Zhao, H, Davis, S.T, Johanson, K.O, Green, S.M, Concha, N.O, Zhou, B.B.
登録日2003-02-04
公開日2003-04-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Chk1 Inhibition by UCN-01
J.Biol.Chem., 277, 2002
3I2S
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BU of 3i2s by Molmil
Crystal structure of the hairpin ribozyme with a 2'OMe substrate and N1-deazaadenosine at position A10
分子名称: 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ...
著者Wedekind, J.E, Spitale, R.C, Krucinska, J.
登録日2009-06-29
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core.
Biochemistry, 48, 2009
8CLK
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BU of 8clk by Molmil
TFIIIC TauA complex
分子名称: General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 3, General transcription factor 3C polypeptide 5, ...
著者Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W.
登録日2023-02-16
公開日2023-06-21
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into human TFIIIC promoter recognition.
Sci Adv, 9, 2023
3DBV
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BU of 3dbv by Molmil
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE MUTANT WITH LEU 33 REPLACED BY THR, THR 34 REPLACED BY GLY, ASP 36 REPLACED BY GLY, LEU 187 REPLACED BY ALA, AND PRO 188 REPLACED BY SER COMPLEXED WITH NAD+
分子名称: GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
著者Didierjean, C, Rahuel-Clermont, S, Vitoux, B, Dideberg, O, Branlant, G, Aubry, A.
登録日1997-01-06
公開日1997-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A crystallographic comparison between mutated glyceraldehyde-3-phosphate dehydrogenases from Bacillus stearothermophilus complexed with either NAD+ or NADP+.
J.Mol.Biol., 268, 1997
6K1D
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BU of 6k1d by Molmil
Crystal structure of EXD2 exonuclease domain soaked in Mn and GMP
分子名称: Exonuclease 3'-5' domain-containing protein 2, MANGANESE (II) ION
著者Park, J, Lee, C.
登録日2019-05-10
公開日2019-05-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination.
Nucleic Acids Res., 47, 2019
6K1C
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BU of 6k1c by Molmil
Crystal structure of EXD2 exonuclease domain soaked in Mg and dGMP
分子名称: Exonuclease 3'-5' domain-containing protein 2, MAGNESIUM ION
著者Park, J, Lee, C.
登録日2019-05-10
公開日2019-05-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination.
Nucleic Acids Res., 47, 2019
1R1K
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BU of 1r1k by Molmil
Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to ponasterone A
分子名称: 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE, Ecdysone receptor, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ...
著者Billas, I.M.L, Iwema, T, Garnier, J.-M, Mitschler, A, Rochel, N, Moras, D, Structural Proteomics in Europe (SPINE)
登録日2003-09-24
公開日2003-11-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.
Nature, 426, 2003
6K18
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Crystal structure of EXD2 exonuclease domain soaked in Mn
分子名称: Exonuclease 3'-5' domain-containing protein 2, MANGANESE (II) ION
著者Park, J, Lee, C.
登録日2019-05-10
公開日2019-05-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination.
Nucleic Acids Res., 47, 2019
6K1A
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Crystal structure of EXD2 exonuclease domain soaked in Mn and Mg
分子名称: Exonuclease 3'-5' domain-containing protein 2, MAGNESIUM ION, MANGANESE (II) ION
著者Park, J, Lee, C.
登録日2019-05-10
公開日2019-05-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination.
Nucleic Acids Res., 47, 2019
3ZQJ
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Mycobacterium tuberculosis UvrA
分子名称: UVRABC SYSTEM PROTEIN A, ZINC ION
著者Rossi, F, Khanduja, J.S, Bortoluzzi, A, Houghton, J, Sander, P, Guthlein, C, Davis, E.O, Springer, B, Bottger, E.C, Relini, A, Penco, A, Muniyappa, K, Rizzi, M.
登録日2011-06-09
公開日2011-06-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The Biological and Structural Characterization of Mycobacterium Tuberculosis Uvra Provides Novel Insights Into its Mechanism of Action
Nucleic Acids Res., 39, 2011

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