PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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5Q1K	PanDDA analysis group deposition -- Crystal Structure of DCLRE1A in complex with FMOPL000074a 分子名称: 2-[4-(1~{H}-pyrazol-3-yl)phenoxy]pyrimidine, DNA cross-link repair 1A protein, MALONATE ION, ... 著者 Newman, J.A, Aitkenhead, H, Lee, S.Y, Kupinska, K, Burgess-Brown, N, Tallon, R, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2017-05-15 公開日 2018-08-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5Q1Z	PanDDA analysis group deposition -- Crystal Structure of DCLRE1A in complex with FMOPL000150a 分子名称: 2-[(4-chlorophenyl)amino]benzamide, DNA cross-link repair 1A protein, MALONATE ION, ... 著者 Newman, J.A, Aitkenhead, H, Lee, S.Y, Kupinska, K, Burgess-Brown, N, Tallon, R, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2017-05-15 公開日 2018-08-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 PanDDA analysis group deposition To Be Published
2KEL	Structure of the transcription regulator SvtR from the hyperthermophilic archaeal virus SIRV1 分子名称: Uncharacterized protein 56B 著者 Guilliere, F, Kessler, A, Peixeiro, N, Sezonov, G, Prangishvili, D, Delepierre, M, Guijarro, J.I. 登録日 2009-01-30 公開日 2009-06-16 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure, function, and targets of the transcriptional regulator SvtR from the hyperthermophilic archaeal virus SIRV1. J.Biol.Chem., 284, 2009
1ZJG	13mer-co 分子名称: 5'-D(*AP*TP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*CP*A)-3', COBALT HEXAMMINE(III), ... 著者 Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G. 登録日 2005-04-28 公開日 2005-05-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site. J.Mol.Biol., 349, 2005
1HGZ	Filamentous Bacteriophage PH75 分子名称: PH75 INOVIRUS MAJOR COAT PROTEIN 著者 Pederson, D.M, Welsh, L.C, Marvin, D.A, Sampson, M, Perham, R.N, Yu, M, Slater, M.R. 登録日 2000-12-17 公開日 2001-06-01 最終更新日 2024-02-14 実験手法 FIBER DIFFRACTION (2.4 Å) 主引用文献 The Protein Capsid of Filamentous Bacteriophage Ph75 from Thermus Thermophilus J.Mol.Biol., 309, 2001
1HH0	Filamentous Bacteriophage PH75 分子名称: PH75 INOVIRUS MAJOR COAT PROTEIN 著者 Pederson, D.M, Welsh, L.C, Marvin, D.A, Sampson, M, Perham, R.N, Yu, M, Slater, M.R. 登録日 2000-12-17 公開日 2001-06-01 最終更新日 2024-02-14 実験手法 FIBER DIFFRACTION (2.4 Å) 主引用文献 The Protein Capsid of Filamentous Bacteriophage Ph75 from Thermus Thermophilus J.Mol.Biol., 309, 2001
1SR4	Crystal Structure of the Haemophilus ducreyi cytolethal distending toxin 分子名称: BROMIDE ION, Cytolethal distending toxin subunit A, cytolethal distending toxin protein B, ... 著者 Nesic, D, Hsu, Y, Stebbins, C.E. 登録日 2004-03-22 公開日 2004-06-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Assembly and Function of a Bacterial Genotoxin Nature, 429, 2004
1ZJF	12mer-spd-P4N 分子名称: 5'-D(*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*C)-3' 著者 Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G. 登録日 2005-04-28 公開日 2005-05-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site. J.Mol.Biol., 349, 2005
2LKM	Structural Basis for Molecular Interactions Involving MRG Domains: Implications in Chromatin Biology 分子名称: Mortality factor 4-like protein 1, PHD finger protein 12 著者 Xie, T, Radhakrishnan, I. 登録日 2011-10-16 公開日 2012-01-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis for molecular interactions involving MRG domains: implications in chromatin biology. Structure, 20, 2012
2JZ0	DSX_short 分子名称: Protein doublesex 著者 Yang, Y, Zhang, W, Bayrer, J.R, Weiss, M.A. 登録日 2007-12-21 公開日 2008-01-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Doublesex and the Regulation of Sexual Dimorphism in Drosophila melanogaster: STRUCTURE, FUNCTION, AND MUTAGENESIS OF A FEMALE-SPECIFIC DOMAIN. J.Biol.Chem., 283, 2008
2F1Q	Solution structure of a DNA Holliday Junction 分子名称: 42-MER, COBALT HEXAMMINE(III) 著者 Wu, B, van Buuren, B.N.M, Schleucher, J, Wijmenga, S.S. 登録日 2005-11-15 公開日 2007-03-20 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The solution structure of a four-way junction in the presence of cobalt ion TO BE PUBLISHED
1HGV	Filamentous Bacteriophage PH75 分子名称: PH75 INOVIRUS MAJOR COAT PROTEIN 著者 Pederson, D.M, Welsh, L.C, Marvin, D.A, Sampson, M, Perham, R.N, Yu, M, Slater, M.R. 登録日 2000-12-15 公開日 2001-06-01 最終更新日 2023-12-13 実験手法 FIBER DIFFRACTION (2.4 Å) 主引用文献 The Protein Capsid of Filamentous Bacteriophage Ph75 from Thermus Thermophilus J.Mol.Biol., 309, 2001
3BKT	Copper-bound C-terminal Domain of NikR 分子名称: COPPER (II) ION, Nickel-responsive regulator 著者 Phillips, C.M, Schreiter, E.R, Drennan, C.L. 登録日 2007-12-07 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Basis of the Metal Specificity for Nickel Regulatory Protein NikR. Biochemistry, 47, 2008
1U2Z	Crystal structure of histone K79 methyltransferase Dot1p from yeast 分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE 著者 Sawada, K, Yang, Z, Horton, J.R, Collins, R.E, Zhang, X, Cheng, X. 登録日 2004-07-20 公開日 2004-09-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase J.Biol.Chem., 279, 2004
3BKU	Apo C-terminal Domain of NikR 分子名称: Nickel-responsive regulator 著者 Phillips, C.M, Schreiter, E.R, Drennan, C.L. 登録日 2007-12-07 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis of the Metal Specificity for Nickel Regulatory Protein NikR. Biochemistry, 47, 2008
2N1D	Solution structure of the MRG15-MRGBP complex 分子名称: MRG/MORF4L-binding protein, Mortality factor 4-like protein 1 著者 Xie, T, Zmysloski, A.M, Zhang, Y, Radhakrishnan, I. 登録日 2015-03-27 公開日 2015-05-27 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Basis for Multi-specificity of MRG Domains. Structure, 23, 2015
2MMY	Solution structure of the RNA recognition motif of human TAF15 分子名称: TATA-binding protein-associated factor 2N 著者 Kashyap, M, Ganguly, A.K, Bhavesh, N.S. 登録日 2014-03-22 公開日 2015-03-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural delineation of stem-loop RNA binding by human TAF15 protein Sci Rep, 5, 2015
1WJ0	Solution Structure of the DNA-Binding Domain of Squamosa Promoter Binding Protein-Like 12 Lacking the Second Zinc-Binding Site 分子名称: ZINC ION, squamosa promoter-binding protein-like 12 著者 Yamasaki, K, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-28 公開日 2004-11-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure of the SBP Domain That Lacks the Second Zinc-Binding Site To be Published
6US2	MTH1 in complex with compound 5 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, N-[5-(2,3-dimethylphenyl)-1,2,3,4-tetrahydro-1,6-naphthyridin-7-yl]acetamide 著者 Newby, Z.E.R, Lansdon, E.B. 登録日 2019-10-24 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.80012655 Å) 主引用文献 Discovery of Potent and Selective MTH1 Inhibitors for Oncology: Enabling Rapid Target (In)Validation. Acs Med.Chem.Lett., 11, 2020
4M3I	X-ray crystal structure of the ruthenium complex [Ru(TAP)2(dppz-{Me2})]2+ bound to d(CCGGTACCGG) 分子名称: (11,12-dimethyldipyrido[3,2-a:2',3'-c]phenazine-kappa~2~N~4~,N~5~)[bis(pyrazino[2,3-f]quinoxaline-kappa~2~N~1~,N~10~)]ruthenium(2+), BARIUM ION, Synthetic DNA CCGGTACCGG 著者 Niyazi, H, Teixeira, S, Mitchell, E, Forsyth, T, Cardin, C. 登録日 2013-08-06 公開日 2014-09-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray crystal structure of the ruthenium complex [Ru(TAP)2(dppz-{Me2})]2+ bound to d(CCGGTACCGG) To be Published
6US3	MTH1 in complex with compound 4 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, N-[5-(2,3-dimethylphenyl)-1,6-naphthyridin-7-yl]acetamide 著者 Newby, Z.E.R, Lansdon, E.B. 登録日 2019-10-24 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.47028923 Å) 主引用文献 Discovery of Potent and Selective MTH1 Inhibitors for Oncology: Enabling Rapid Target (In)Validation. Acs Med.Chem.Lett., 11, 2020
6US4	MTH1 in complex with compound 32 分子名称: 5-(2,3-dichlorophenyl)[1,2,4]triazolo[1,5-a]pyridin-2-amine, 7,8-dihydro-8-oxoguanine triphosphatase 著者 Newby, Z.E.R, Lansdon, E.B. 登録日 2019-10-24 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95032907 Å) 主引用文献 Discovery of Potent and Selective MTH1 Inhibitors for Oncology: Enabling Rapid Target (In)Validation. Acs Med.Chem.Lett., 11, 2020
4MMJ	crystal structure of YafQ from E.coli strain BL21(DE3) 分子名称: Addiction module toxin, RelE/StbE family, SULFATE ION 著者 Liang, Y, Gao, Z, Liu, Q, Dong, Y. 登録日 2013-09-09 公開日 2014-06-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ J.Biol.Chem., 289, 2014
2G9E	Protonation-mediated structural flexibility in the F conjugation regulatory protein, TRAM 分子名称: Protein traM 著者 Lu, J, Edwards, R.A, Wong, J.J, Manchak, J, Scott, P.G, Frost, L.S, Glover, J.N. 登録日 2006-03-06 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM. Embo J., 25, 2006
5ANT	Potent and selective inhibitors of MTH1 probe its role in cancer cell survival 分子名称: 2-(2-methoxyethoxy)-6-(methylamino)-9-(phenylmethyl)-7H-purin-8-one, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE 著者 Kettle, J.G, Alwan, H, Bista, M, Breed, J, Kack, H, Eckersley, K, Foote, K.M, Fillery, S, Goodwin, L, Jones, D, Lau, A, Nissink, J.W.M, Read, J, Scott, J, Taylor, B, Walker, G, Wissler, L. 登録日 2015-09-08 公開日 2016-03-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Potent and Selective Inhibitors of Mth1 Probe its Role in Cancer Cell Survival. J.Med.Chem., 59, 2016

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