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2JX1
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Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA
分子名称: DNA (5'-D(*DAP*DCP*DCP*DGP*DAP*DAP*DAP*DGP*DTP*DTP*DCP*DAP*DC)-3'), DNA (5'-D(*DGP*DTP*DGP*DAP*DAP*DCP*DTP*DTP*DTP*DCP*DGP*DGP*DT)-3'), Myelin transcription factor 1
著者Gamsjaeger, R, Swanton, M.K, Kobus, F.J, Lehtomaki, E, Lowry, J.A, Kwan, A.H, Matthews, J.M, Mackay, J.P.
登録日2007-11-01
公開日2007-12-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA
To be Published
2JWZ
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Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins
分子名称: Ubiquitin
著者Haririnia, A, Verma, R, Purohit, N, Twarog, M, Deshaies, R, Bolon, D, Fushman, D.
登録日2007-10-31
公開日2008-01-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins.
J.Mol.Biol., 375, 2008
2JPC
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SSRB DNA Binding Protein
分子名称: SsrB
著者Liao, X, Kenney, L, Sheng, W, Integrated Center for Structure and Function Innovation (ISFI)
登録日2007-05-03
公開日2007-07-03
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献SSRB DNA Binding Protein
To be Published
2K0N
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Solution Structure of Yeast Gal11p kix domain
分子名称: Mediator of RNA polymerase II transcription subunit 15
著者Arthanari, H, Frueh, D.P, Wagner, G.K, Naar, A.M.
登録日2008-02-04
公開日2008-03-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A nuclear receptor-like pathway regulating multidrug resistance in fungi.
Nature, 452, 2008
2JV5
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Nogo54
分子名称: Reticulon-4
著者Li, M, Song, J.
登録日2007-09-12
公開日2008-09-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure-based design of buffer-soluble Nogo54: a molecular mimic of Nogo-66 to inhibit CNS neuron regeneration
To be Published
2JW2
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Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
分子名称: StAR-related lipid transfer protein 13
著者Li, H, Sze, K, Fung, K.
登録日2007-10-03
公開日2008-10-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
To be Published
2K00
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Solution structure of the talin F3 in complex with layilin cytodomain
分子名称: Layilin, Talin-1
著者Wegener, K.L, Barsukov, I.L.
登録日2008-01-23
公開日2008-09-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain
J.Mol.Biol., 382, 2008
2JPZ
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Human telomere DNA quadruplex structure in K+ solution hybrid-2 form
分子名称: DNA (26-MER)
著者Dai, J, Carver, M, Punchihewa, C, Jones, R, Yang, D.
登録日2007-05-25
公開日2007-12-04
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence
Nucleic Acids Res., 35, 2007
2K45
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C2A domain of synaptototagmin I solution structure in the FGF-1-C2A binary complex: key component in the fibroblast growthfactor non-classical pathway
分子名称: Synaptotagmin-1
著者Mohan, S.K, Yu, C.
登録日2008-05-28
公開日2009-06-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release
To be Published
2K4E
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Solution structure of the HIV-2 UNMYRISTOYLATED MATRIX PROTEIN
分子名称: HIV-2 unmyristoylated matrix protein
著者Saad, J.S, Ablan, S.D, Ghanam, R.H, Kim, A, Andrews, K, Nagashima, K, Freed, E.O, Summers, M.F.
登録日2008-06-07
公開日2008-08-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting.
J.Mol.Biol., 382, 2008
2J0M
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Crystal structure a two-chain complex between the FERM and kinase domains of focal adhesion kinase.
分子名称: 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1
著者Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J.
登録日2006-08-03
公開日2007-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Autoinhibition of Focal Adhesion Kinase.
Cell(Cambridge,Mass.), 129, 2007
2J0K
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Crystal structure of a fragment of focal adhesion kinase containing the FERM and kinase domains.
分子名称: 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1
著者Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J.
登録日2006-08-03
公開日2007-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Autoinhibition of Focal Adhesion Kinase.
Cell(Cambridge,Mass.), 129, 2007
2J38
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CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
分子名称: 5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ...
著者Senger, S, Convery, M.A, Chan, C, Watson, N.S.
登録日2006-08-18
公開日2006-09-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Arylsulfonamides: A Study of the Relationship between Activity and Conformational Preferences for a Series of Factor Xa Inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2J0J
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Crystal structure of a fragment of focal adhesion kinase containing the FERM and kinase domains.
分子名称: 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1
著者Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J.
登録日2006-08-03
公開日2007-06-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Autoinhibition of Focal Adhesion Kinase
Cell(Cambridge,Mass.), 129, 2007
2J2U
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CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
分子名称: 5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-SULFONAMIDE, COAGULATION FACTOR X HEAVY CHAIN, COAGULATION FACTOR X LIGHT CHAIN
著者Senger, S, Convery, M.A, Chan, C, Watson, N.S.
登録日2006-08-17
公開日2006-09-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Arylsulfonamides: A Study of the Relationship between Activity and Conformational Preferences for a Series of Factor Xa Inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2J94
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CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
分子名称: 5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE, CALCIUM ION, COAGULATION FACTOR X
著者Chan, C, Borthwick, A.D, Brown, D, Campbell, M, Chaudry, L, Chung, C.W, Convery, M.A, Hamblin, J.N, Johnstone, L, Kelly, H.A, Kleanthous, S, Burns-Kurtis, C.L, Patikis, A, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Toomey, J.R, Watson, N.S, Weston, H.E, Whitworth, C, Young, R.J, Zhou, P.
登録日2006-11-02
公開日2007-03-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-Morpholin-4-Yl-2-Oxoethyl]-2-Oxopyrrolidin-3-Yl}Sulfonamides.
J.Med.Chem., 50, 2007
2J0L
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Crystal structure of a the active conformation of the kinase domain of focal adhesion kinase with a phosphorylated activation loop.
分子名称: FOCAL ADHESION KINASE 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J.
登録日2006-08-03
公開日2007-06-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Autoinhibition of Focal Adhesion Kinase
Cell(Cambridge,Mass.), 129, 2007
2J34
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CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
分子名称: 6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ...
著者Senger, S, Convery, M.A, Chan, C, Watson, N.S.
登録日2006-08-18
公開日2006-09-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Arylsulfonamides: A Study of the Relationship between Activity and Conformational Preferences for a Series of Factor Xa Inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2J3S
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Crystal structure of the human filamin A Ig domains 19 to 21
分子名称: 1,4-DIETHYLENE DIOXIDE, BROMIDE ION, FILAMIN-A, ...
著者Kiema, T.-R, Ylanne, J.
登録日2006-08-23
公開日2007-10-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Three Tandem Filamin Domains Reveals Auto-Inhibition of Ligand-Binding.
Embo J., 26, 2007
2J8U
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Large CDR3a loop alteration as a function of MHC mutation.
分子名称: AHIII TCR ALPHA CHAIN, AHIII TCR BETA CHAIN, Beta-2-microglobulin, ...
著者Miller, P.J, Benhar, Y.P, Biddison, W, Collins, E.J.
登録日2006-10-27
公開日2007-10-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Single MHC mutation eliminates enthalpy associated with T cell receptor binding.
J. Mol. Biol., 373, 2007
2J7I
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ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETERODIMER
分子名称: CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2
著者Moncalian, G, Cardenes, N, Deribe, Y.L, Spinola-Amilibia, M, Dikic, I, Bravo, J.
登録日2006-10-09
公開日2006-11-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Atypical Polyproline Recognition by the Cms N-Terminal Src Homology 3 Domain.
J.Biol.Chem., 281, 2006
2J6O
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ATYPICAL POLYPROLINE RECOGNITION BY THE CMS N-TERMINAL SH3 DOMAIN. CMS:CD2 HETEROTRIMER
分子名称: CD2-ASSOCIATED PROTEIN, T-CELL SURFACE ANTIGEN CD2
著者Moncalian, G, Cardenes, N, Deribe, Y.L, Spinola-Amilibia, M, Dikic, I, Bravo, J.
登録日2006-10-02
公開日2006-10-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Atypical Polyproline Recognition by the Cms N-Terminal SH3 Domain.
J.Biol.Chem., 281, 2006
2IZQ
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Gramicidin D complex with KI
分子名称: GRAMICIDIN D, IODIDE ION, METHANOL, ...
著者Olczak, A, Glowka, M.L, Szczesio, M, Bojarska, J, Duax, W.L, Burkhart, B.M, Wawrzak, Z.
登録日2006-07-26
公開日2007-01-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (0.8 Å)
主引用文献Nonstoichiometric Complex of Gramicidin D with Ki at 0.80 A Resolution.
Acta Crystallogr.,Sect.D, 63, 2007
2J4N
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Double dockerin from Piromyces equi Cel45A
分子名称: ENDOGLUCANASE 45A
著者Nagy, T, Tunnicliffe, R.B, Higgins, L.D, Walters, C, Gilbert, H.J, Williamson, M.P.
登録日2006-09-01
公開日2007-09-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Characterization of a Double Dockerin from the Cellulosome of the Anaerobic Fungus Piromyces Equi.
J.Mol.Biol., 373, 2007
2J4I
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CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
分子名称: 1-PYRROLIDINEACETAMIDE, 3-[[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]AMINO]-ALPHA-METHYL-N-(1-METHYLETHYL)-N-[2-[(METHYLSULFONYL)AMINO]ETHYL]-2-OXO-, (ALPHAS,3S)-, ...
著者Young, R.J, Campbell, M, Borthwick, A.D, Brown, D, Chan, C, Convery, M.A, Crowe, M.C, Dayal, S, Diallo, H, Kelly, H.A, Paul King, N, Kleanthous, S, Kurtis, C.L, Mason, A.M, Mordaunt, J.E, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Smith, P.W, Watson, N.S, Weston, H.E, Zhou, P.
登録日2006-08-31
公開日2006-09-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure- and Property-Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Acyclic Alanyl Amides as P4 Motifs.
Bioorg.Med.Chem.Lett., 16, 2006

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