3OJX
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![BU of 3ojx by Molmil](/molmil-images/mine/3ojx) | Disulfide crosslinked cytochrome P450 reductase inactive | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Xia, C, Hamdane, D, Shen, A, Choi, V, Kasper, C, Zhang, H, Im, S.-C, Waskell, L, Kim, J.-J.P. | 登録日 | 2010-08-23 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding. J.Biol.Chem., 286, 2011
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2WIV
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![BU of 2wiv by Molmil](/molmil-images/mine/2wiv) | Cytochrome-P450 XplA heme domain P21 | 分子名称: | CYTOCHROME P450-LIKE PROTEIN XPLA, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sabbadin, F, Jackson, R, Bruce, N.C, Grogan, G. | 登録日 | 2009-05-18 | 公開日 | 2009-08-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The 1.5-A Structure of Xpla-Heme, an Unusual Cytochrome P450 Heme Domain that Catalyzes Reductive Biotransformation of Royal Demolition Explosive. J.Biol.Chem., 284, 2009
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3OJW
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![BU of 3ojw by Molmil](/molmil-images/mine/3ojw) | Disulfide crosslinked cytochrome P450 reductase inactive | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH-cytochrome P450 reductase | 著者 | Xia, C, Hamdane, D, Shen, A, Choi, V, Kasper, C, Zhang, H, Im, S.-C, Waskell, L, Kim, J.-J.P. | 登録日 | 2010-08-23 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding. J.Biol.Chem., 286, 2011
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4L0F
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2A1M
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3R1B
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![BU of 3r1b by Molmil](/molmil-images/mine/3r1b) | Open crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene | 分子名称: | (4-tert-butylphenyl)acetaldehyde, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, ... | 著者 | Gay, S.C, Zhang, H, Stout, C.D, Hollenberg, P.F, Halpert, J.R. | 登録日 | 2011-03-09 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial Enzymatic Activity. Biochemistry, 50, 2011
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3R1A
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![BU of 3r1a by Molmil](/molmil-images/mine/3r1a) | Closed crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene | 分子名称: | (4-tert-butylphenyl)acetaldehyde, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Gay, S.C, Zhang, H, Stout, C.D, Hollenberg, P.F, Halpert, J.R. | 登録日 | 2011-03-09 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial Enzymatic Activity. Biochemistry, 50, 2011
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2A1O
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2A1N
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![BU of 2a1n by Molmil](/molmil-images/mine/2a1n) | |
7SUX
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![BU of 7sux by Molmil](/molmil-images/mine/7sux) | |
7SV0
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![BU of 7sv0 by Molmil](/molmil-images/mine/7sv0) | |
7SUZ
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3TDA
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![BU of 3tda by Molmil](/molmil-images/mine/3tda) | Competitive replacement of thioridazine by prinomastat in crystals of cytochrome P450 2D6 | 分子名称: | Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, Prinomastat, ... | 著者 | Wang, A, Stout, C.D, Johnson, E.F. | 登録日 | 2011-08-10 | 公開日 | 2012-08-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015
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6J79
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1T85
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![BU of 1t85 by Molmil](/molmil-images/mine/1t85) | Crystal Structure of the Ferrous CO-bound Cytochrome P450cam Mutant (L358P/C334A) | 分子名称: | CAMPHOR, CARBON MONOXIDE, Cytochrome P450-cam, ... | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | 登録日 | 2004-05-11 | 公開日 | 2004-06-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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4I91
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![BU of 4i91 by Molmil](/molmil-images/mine/4i91) | Crystal Structure of Cytochrome P450 2B6 (Y226H/K262R) in complex with alpha-Pinene. | 分子名称: | (+)-alpha-Pinene, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... | 著者 | Shah, M.B, Stout, C.D, Halpert, J.R. | 登録日 | 2012-12-04 | 公開日 | 2013-07-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and Thermodynamic Basis of (+)-alpha-Pinene Binding to Human Cytochrome P450 2B6. J.Am.Chem.Soc., 135, 2013
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1T86
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![BU of 1t86 by Molmil](/molmil-images/mine/1t86) | Crystal Structure of the Ferrous Cytochrome P450cam Mutant (L358P/C334A) | 分子名称: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | 登録日 | 2004-05-11 | 公開日 | 2004-05-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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1T87
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![BU of 1t87 by Molmil](/molmil-images/mine/1t87) | Crystal Structure of the Ferrous CO-bound Cytochrome P450cam (C334A) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CARBON MONOXIDE, ... | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | 登録日 | 2004-05-11 | 公開日 | 2004-05-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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1T88
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![BU of 1t88 by Molmil](/molmil-images/mine/1t88) | Crystal Structure of the Ferrous Cytochrome P450cam (C334A) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | 登録日 | 2004-05-11 | 公開日 | 2004-05-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
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1BU7
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6J7A
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![BU of 6j7a by Molmil](/molmil-images/mine/6j7a) | Fusion protein of heme oxygenase-1 and NADPH cytochrome P450 reductase (17aa) | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Heme oxygenase 1,NADPH--cytochrome P450 reductase, ... | 著者 | Sugishima, M, Sato, H, Wada, K, Yamamoto, K. | 登録日 | 2019-01-17 | 公開日 | 2019-04-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.269 Å) | 主引用文献 | Crystal structure of a NADPH-cytochrome P450 oxidoreductase (CYPOR) and heme oxygenase 1 fusion protein implies a conformational change in CYPOR upon NADPH/NADP+binding. Febs Lett., 593, 2019
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2Q9F
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![BU of 2q9f by Molmil](/molmil-images/mine/2q9f) | Crystal structure of human cytochrome P450 46A1 in complex with cholesterol-3-sulphate | 分子名称: | CHOLEST-5-EN-3-YL HYDROGEN SULFATE, Cytochrome P450 46A1, GLYCEROL, ... | 著者 | White, M.A, Mast, N.V, Johnson, E.F, Stout, C.D, Pikuleva, I.A. | 登録日 | 2007-06-12 | 公開日 | 2008-06-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1BVY
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![BU of 1bvy by Molmil](/molmil-images/mine/1bvy) | COMPLEX OF THE HEME AND FMN-BINDING DOMAINS OF THE CYTOCHROME P450(BM-3) | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, PROTEIN (CYTOCHROME P450 BM-3), ... | 著者 | Sevrioukova, I.F, Li, H, Zhang, H, Peterson, J.A, Poulos, T.L. | 登録日 | 1998-09-21 | 公開日 | 1999-02-23 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structure of a cytochrome P450-redox partner electron-transfer complex. Proc.Natl.Acad.Sci.USA, 96, 1999
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6J7I
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![BU of 6j7i by Molmil](/molmil-images/mine/6j7i) | Fusion protein of heme oxygenase-1 and NADPH cytochrome P450 reductase (15aa) | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Heme oxygenase 1,NADPH--cytochrome P450 reductase, ... | 著者 | Sugishima, M, Sato, H, Wada, K, Yamamoto, K. | 登録日 | 2019-01-18 | 公開日 | 2019-04-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of a NADPH-cytochrome P450 oxidoreductase (CYPOR) and heme oxygenase 1 fusion protein implies a conformational change in CYPOR upon NADPH/NADP+binding. Febs Lett., 593, 2019
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1YRC
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![BU of 1yrc by Molmil](/molmil-images/mine/1yrc) | X-ray Crystal Structure of hydrogenated Cytochrome P450cam | 分子名称: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | 著者 | Meilleur, F, Dauvergne, M.-T, Schlichting, I, Myles, D.A.A. | 登録日 | 2005-02-03 | 公開日 | 2005-02-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Production and X-ray crystallographic analysis of fully deuterated cytochrome P450cam. Acta Crystallogr.,Sect.D, 61, 2005
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