PDB: 257 件ウェブページステータス検索Chemie searchBIRD

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8G7U	Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-semi-closed end) 分子名称: Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... 著者 Wang, W, Pyle, A.M. 登録日 2023-02-17 公開日 2023-11-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization. Nat Commun, 14, 2023
8G7T	Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-end) 分子名称: Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... 著者 Wang, W, Pyle, A.M. 登録日 2023-02-17 公開日 2023-11-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization. Nat Commun, 14, 2023
8G7V	Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) 分子名称: Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... 著者 Wang, W, Pyle, A.M. 登録日 2023-02-17 公開日 2023-11-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization. Nat Commun, 14, 2023
6KIX	Cryo-EM structure of human MLL1-NCP complex, binding mode1 分子名称: DNA (145-MER), GLUTAMINE, Histone H2A, ... 著者 Huang, J, Xue, H, Yao, T. 登録日 2019-07-20 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
6KIV	Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom) 分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... 著者 Huang, J, Xue, H, Yao, T. 登録日 2019-07-20 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
6KIZ	Cryo-EM structure of human MLL1-NCP complex, binding mode2 分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... 著者 Huang, J, Xue, H, Yao, T. 登録日 2019-07-20 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
8UQ2	Structure of human RyR2-S2808D in the subprimed state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-10-23 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UQ3	Structure of human RyR2-S2808D in the closed state in the presence of ARM210 分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-10-23 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UQ4	Structure of human RyR2-S2808D in the subprimed state in the presence of H2O2/NOC-12/GSH 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-10-23 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UQ5	Structure of human RyR2-S2808D in the primed state in the presence of Rapamycin 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Ryanodine receptor 2, ZINC ION 著者 Miotto, M.C, Marks, A.R. 登録日 2023-10-23 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.96 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXE	Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210 分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXC	Structure of PKA phosphorylated human RyR2-R420Q in the primed state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXG	Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210 分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXH	Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.52 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXF	Structure of PKA phosphorylated human RyR2-R420W in the primed state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXL	Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and calmodulin 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXI	Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8UXM	Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ... 著者 Miotto, M.C, Marks, A.R. 登録日 2023-11-09 公開日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders To Be Published
8VK3	Structure of mouse RyR1 in complex with S100A1 (EGTA-only dataset) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Protein S100A1, ... 著者 Weninger, G, Marks, A.R. 登録日 2024-01-08 公開日 2024-01-24 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Structural insights into the regulation of RyR1 by S100A1. Proc.Natl.Acad.Sci.USA, 121, 2024
8VJK	Structure of mouse RyR1 (high-Ca2+/CFF/ATP dataset) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... 著者 Weninger, G, Marks, A.R. 登録日 2024-01-07 公開日 2024-01-17 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Structural insights into the regulation of RyR1 by S100A1. Proc.Natl.Acad.Sci.USA, 121, 2024
8VJJ	Structure of mouse RyR1 (EGTA-only dataset) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ... 著者 Weninger, G, Marks, A.R. 登録日 2024-01-07 公開日 2024-01-17 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.53 Å) 主引用文献 Structural insights into the regulation of RyR1 by S100A1. Proc.Natl.Acad.Sci.USA, 121, 2024
8VK4	Structure of mouse RyR1 in complex with S100A1 (high-Ca2+/CFF/ATP dataset) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... 著者 Weninger, G, Marks, A.R. 登録日 2024-01-08 公開日 2024-02-07 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Structural insights into the regulation of RyR1 by S100A1. Proc.Natl.Acad.Sci.USA, 121, 2024
5TAU	Structure of rabbit RyR1 (Caffeine/ATP/EGTA dataset, class 3) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-10 公開日 2016-10-12 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
5TAT	Structure of rabbit RyR1 (Caffeine/ATP/EGTA dataset, class 2) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-10 公開日 2016-10-12 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
5TAZ	Structure of rabbit RyR1 (ryanodine dataset, class 3) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-10 公開日 2016-10-12 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016

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