7W39
 
 | | Structure of USP14-bound human 26S proteasome in state EA2.1_UBL | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W3B
 | | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14 | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W3G
 | | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14 | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W3J
 | | Structure of USP14-bound human 26S proteasome in substrate-inhibited state SC_USP14 | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W3C
 | | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14 | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W3A
 | | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED4_USP14 | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W3F
 | | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14 | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W37
 | | Structure of USP14-bound human 26S proteasome in state EA1_UBL | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W38
 | | Structure of USP14-bound human 26S proteasome in state EA2.0_UBL | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W3K
 | | Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14 | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7Z6H
 | | Structure of DNA-bound human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp | | 分子名称: | Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1,Cell cycle checkpoint protein RAD17, Checkpoint protein HUS1, ... | | 著者 | Day, M, Oliver, A.W, Pearl, L.H. | | 登録日 | 2022-03-11 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction.
Nucleic Acids Res., 50, 2022
|
|
7STE
 | | Rad24-RFC ADP state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Checkpoint protein RAD24, ... | | 著者 | Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K. | | 登録日 | 2021-11-12 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | Mechanisms of loading and release of the 9-1-1 checkpoint clamp.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7TDO
 | | Cryo-EM structure of transmembrane AAA+ protease FtsH in the ADP state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent zinc metalloprotease FtsH | | 著者 | Liu, W, Schoonen, M, Wang, T, McSweeney, S, Liu, Q. | | 登録日 | 2022-01-02 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Cryo-EM structure of transmembrane AAA+ protease FtsH in the ADP state.
Commun Biol, 5, 2022
|
|
7STB
 | | Closed state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DNA (5'-D(P*CP*GP*CP*TP*CP*CP*TP*TP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*CP*C)-3'), ... | | 著者 | Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K. | | 登録日 | 2021-11-12 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Mechanisms of loading and release of the 9-1-1 checkpoint clamp.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7ST9
 | | Open state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DNA (5'-D(P*CP*GP*CP*TP*CP*CP*TP*TP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*CP*C)-3'), ... | | 著者 | Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K. | | 登録日 | 2021-11-12 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Mechanisms of loading and release of the 9-1-1 checkpoint clamp.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7WUB
 | | Cryo-EM structure of dodecamer P97 | | 分子名称: | 3-[3-cyclopentylsulfanyl-5-[[3-methyl-4-(4-methylsulfonylphenyl)phenoxy]methyl]-1,2,4-triazol-4-yl]pyridine, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | 著者 | Liu, S, Wang, T. | | 登録日 | 2022-02-08 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM structure of dodecamer P97 at 2.99 Angstroms resolution
To Be Published
|
|
7SGZ
 | | Structure of the yeast Rad24-RFC loader bound to DNA and the closed 9-1-1 clamp | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, Crick strand, ... | | 著者 | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | | 登録日 | 2021-10-07 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7SH2
 | | Structure of the yeast Rad24-RFC loader bound to DNA and the open 9-1-1 clamp | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, Crick strand, ... | | 著者 | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | | 登録日 | 2021-10-07 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7VHP
 | | Structural insights into the membrane microdomain organization by SPFH family proteins | | 分子名称: | ATP-dependent zinc metalloprotease FtsH, Modulator of FtsH protease HflC, Protein HflK | | 著者 | Ma, C.Y, Wang, C.K, Luo, D.Y, Yan, L, Yang, W.X, Li, N.N, Gao, N. | | 登録日 | 2021-09-22 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Structural insights into the membrane microdomain organization by SPFH family proteins.
Cell Res., 32, 2022
|
|
7QO5
 | | 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | | 著者 | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | | 登録日 | 2021-12-23 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
|
|
7SWL
 | | CryoEM structure of the N-terminal-deleted Rix7 AAA-ATPase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S. | | 登録日 | 2021-11-20 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Pnas Nexus, 1, 2022
|
|
7T0V
 | | CryoEM structure of the crosslinked Rix7 AAA-ATPase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S. | | 登録日 | 2021-11-30 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Pnas Nexus, 1, 2022
|
|
7T3I
 | |
7VCU
 | | Human p97 double hexamer conformer I with D1-ATPgammaS and D2-ADP bound | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | 登録日 | 2021-09-04 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
|
|
7VCT
 | | Human p97 single hexamer conformer III with D1-ATPgammaS and D2-ADP bound | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Gao, H, Li, F, Shi, Z, Li, Y, Yu, H. | | 登録日 | 2021-09-04 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state.
Cell Discov, 8, 2022
|
|
