PDB: 36667 件ウェブページステータス検索Chemie searchBIRD

---

8YBH	Crystal structure of lysozyme by macromolecular crystallography 分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION 著者 Nam, K.H. 登録日 2024-02-14 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of lysozyme by macromolecular crystallography To Be Published
8RZV	Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA 分子名称: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-02-13 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA To Be Published
8RZW	A fragment-based inhibitor of SHP2 分子名称: 3,5-bis(chloranyl)pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11 著者 Cleasby, A, Price, A. 登録日 2024-02-13 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). J.Med.Chem., 67, 2024
8S06	A fragment-based inhibitor of SHP2 分子名称: 1H-pyrrolo[3,2-b]pyridin-7-amine, Tyrosine-protein phosphatase non-receptor type 11 著者 Cleasby, A, Price, A. 登録日 2024-02-13 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). J.Med.Chem., 67, 2024
8RZY	A fragment-based inhibitor of SHP2 分子名称: 1H-pyrrolo[3,2-b]pyridin-5-amine, DIMETHYL SULFOXIDE, Tyrosine-protein phosphatase non-receptor type 11 著者 Cleasby, A, Price, A. 登録日 2024-02-13 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). J.Med.Chem., 67, 2024
8S07	A fragment-based inhibitor of SHP2 分子名称: 7-azanyl-N-pyridin-3-yl-3H-pyrrolo[3,2-b]pyridine-2-carboxamide, DIMETHYL SULFOXIDE, FORMIC ACID, ... 著者 Cleasby, A, Price, A. 登録日 2024-02-13 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). J.Med.Chem., 67, 2024
8S01	A fragment-based inhibitor of SHP2 分子名称: 3-(4-chlorophenyl)-1H-pyrazole, Tyrosine-protein phosphatase non-receptor type 11 著者 Cleasby, A, Price, A. 登録日 2024-02-13 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). J.Med.Chem., 67, 2024
8S04	A fragment-based inhibitor of SHP2 分子名称: N-(1H-indol-7-yl)methanesulfonamide, Tyrosine-protein phosphatase non-receptor type 11 著者 Cleasby, A, Price, A. 登録日 2024-02-13 公開日 2024-03-20 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). J.Med.Chem., 67, 2024
8VZZ	Q108K:K40L:T51V:T53S:Y19W:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V 分子名称: (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2 著者 Nosssoni, Z, Bingham, C.R, Geiger, J.H, Borhan, B. 登録日 2024-02-13 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Regulation of Emission via a Protein-Bound Fluorophore To Be Published
8W02	Q108K:K40L:T51V:T53S:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V 分子名称: (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2 著者 Ghanbarpour, A, Geiger, J.H, Borhan, B. 登録日 2024-02-13 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Regulation of Emission via a Protein-Bound Fluorophore To Be Published
8W00	Q108K:K40L:T51V:T53S:Y19W:R58W:L117E mutant of hCRBPII bound to synthetic fluorophore TD-1V 分子名称: (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2 著者 Nossoni, Z, Bingham, C.R, Geiger, J.H. 登録日 2024-02-13 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Regulation of Emission via a Protein-Bound Fluorophore To Be Published
8VZY	Q108K:K40L:T51V:T53S:R58Y mutant of hCRBPII bound to synthetic fluorophore TD-1V 分子名称: (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2 著者 Nossoni, Z, Bingham, C.R, Geiger, J.H, Borhan, B. 登録日 2024-02-13 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Regulation of Emission via a Protein-Bound Fluorophore To Be Published
8VZX	Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V 分子名称: (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2 著者 Nossoni, Z, Bingham, C.R, Geiger, J.H. 登録日 2024-02-13 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Regulation of Emission via a Protein-Bound Fluorophore To Be Published
8VZ7	Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan 分子名称: Cytochrome P450 2C9, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Shah, M.B. 登録日 2024-02-11 公開日 2024-06-12 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan. J.Inorg.Biochem., 258, 2024
8RXX	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : LM32Cs3H1 sKO STRAIN 分子名称: 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... 著者 Rajan, K.S, Yonath, A. 登録日 2024-02-08 公開日 2024-05-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
8RXH	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN 分子名称: (2S)-2-[2-[4-[[(2R,3S,4S)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid, 40S ribosomal protein S12, 40S ribosomal protein S14, ... 著者 Rajan, K.S, Yonath, A. 登録日 2024-02-07 公開日 2024-05-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
8YA1	HEN EGG WHITE LYSOZYME 分子名称: Lysozyme C 著者 Zhang, C.Y, Xu, Q, Wang, W.W, Zhou, H. 登録日 2024-02-07 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Crystallographic data collection using a multilayer monochromator on an undulator beamline at SSRF To Be Published
8YA4	Crystal structure of a lysozyme form hen egg white 分子名称: Lysozyme C 著者 Zhang, C.Y, Xu, Q, Wang, W.W, Zhou, H. 登録日 2024-02-07 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystallographic data collection using a multilayer monochromator on an undulator beamline at SSRF To Be Published
8Y9W	CRYSTAL STRUCTURE OF A LYSOZYME FROM HEN EGG WHITE 分子名称: Lysozyme C 著者 Zhang, C.Y, Xu, Q, Zhou, H, Wang, Q.S. 登録日 2024-02-07 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic data collection using a multilayer monochromator on an undulator beamline at SSRF To Be Published
8VXD	Structure of Casein kinase I isoform delta (CK1d) complexed with inhibitor 7 分子名称: (4P)-4-[(3P)-3-(5-fluoropyridin-2-yl)-1-methyl-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine, Casein kinase I isoform delta 著者 Thompson, A.A, Milligan, C.M, Sharma, S. 登録日 2024-02-04 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Structure-Based Optimization of Selective and Brain Penetrant CK1 delta Inhibitors for the Treatment of Circadian Disruptions. Acs Med.Chem.Lett., 15, 2024
8VXF	Structure of Casein kinase I isoform delta (CK1d) complexed with inhibitor 15 分子名称: (2P,3P,8S)-2-(5-fluoropyridin-2-yl)-6,6-dimethyl-3-(1H-pyrazolo[3,4-b]pyridin-4-yl)-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine, Casein kinase I isoform delta 著者 Thompson, A.A, Milligan, C.M, Sharma, S. 登録日 2024-02-04 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structure-Based Optimization of Selective and Brain Penetrant CK1 delta Inhibitors for the Treatment of Circadian Disruptions. Acs Med.Chem.Lett., 15, 2024
8VXE	Structure of p38 alpha (Mitogen-activated protein kinase 14) complexed with inhibitor 6 分子名称: (4M)-4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine, Mitogen-activated protein kinase 14 著者 Blaesse, M, Steinbacher, S, Shaffer, P.L, Sharma, S, Thompson, A.A. 登録日 2024-02-04 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-Based Optimization of Selective and Brain Penetrant CK1 delta Inhibitors for the Treatment of Circadian Disruptions. Acs Med.Chem.Lett., 15, 2024
8Y7E	Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part 分子名称: PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... 著者 Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. 登録日 2024-02-04 公開日 2024-03-13 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.66 Å) 主引用文献 Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome. Science, 383, 2024
8RVT	Structure of full-length human insulin fibrils 分子名称: Insulin A chain, Insulin B chain 著者 Bardiaux, B, Suladze, S, Reif, B. 登録日 2024-02-02 公開日 2024-05-29 最終更新日 2024-06-12 実験手法 SOLID-STATE NMR 主引用文献 Atomic resolution structure of full-length human insulin fibrils. Proc.Natl.Acad.Sci.USA, 121, 2024
8VX0	CRYSTAL STRUCTURE OF CYP2C9*14 IN COMPLEX WITH LOSARTAN 分子名称: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ... 著者 Shah, M.B. 登録日 2024-02-02 公開日 2024-06-12 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan. J.Inorg.Biochem., 258, 2024

<12345678910111213141516>