PDB: 5605 件ウェブページステータス検索Chemie searchBIRD

---

8FBI	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains 分子名称: KWOCA_39 著者 Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P. 登録日 2022-11-29 公開日 2023-03-22 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3.61 Å) 主引用文献 Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023
2JWU	Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function 分子名称: Gb88 著者 He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. 登録日 2007-10-25 公開日 2008-09-09 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 NMR structures of two designed proteins with high sequence identity but different fold and function Proc.Natl.Acad.Sci.Usa, 105, 2008
8CCR	Crystal structure of the T19D mutant of the de novo diheme binding 4D2 分子名称: (2S)-2-hydroxybutanedioic acid, 4D2 (mutant T19D), CHLORIDE ION, ... 著者 Barringer, R, Anderson, R. 登録日 2023-01-27 公開日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An expandable, modular de novo protein platform for precision redox engineering. Proc.Natl.Acad.Sci.USA, 120, 2023
1L4X	Octameric de novo designed peptide 分子名称: CHLORIDE ION, MAGNESIUM ION, SIN-ASP-GLU-LEU-GLU-ARG-ALA-ILE-ARG-GLU-LEU-ALA-ALA-ARG-ILE-LYS-NH2 著者 Meier, M, Lustig, A, Aebi, U, Burkhard, P. 登録日 2002-03-06 公開日 2002-11-13 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Removing an interhelical salt bridge abolishes coiled-coil formation in a de novo designed peptide J.STRUCT.BIOL., 137, 2002
7OT8	DeNovoTIM6-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 2) 分子名称: DeNovoTIM6-SB, SULFATE ION 著者 Kordes, S, Romero-Romero, S, Hocker, B. 登録日 2021-06-09 公開日 2021-12-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7OSU	sTIM11noCys-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 1) 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Romero-Romero, S, Kordes, S, Hocker, B. 登録日 2021-06-09 公開日 2021-12-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7OT7	sTIM11noCys-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 2) 分子名称: sTIM11noCys-SB 著者 Romero-Romero, S, Kordes, S, Hocker, B. 登録日 2021-06-09 公開日 2021-12-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7P12	DeNovoTIM13-SB, a de novo designed TIM barrel with a salt-bridge cluster 分子名称: CHLORIDE ION, DeNovoTIM13-SB, PHOSPHATE ION 著者 Kordes, S, Romero-Romero, S, Hocker, B. 登録日 2021-07-01 公開日 2021-12-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7OSV	DeNovoTIM6-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 1) 分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, DeNovoTIM6-SB, ... 著者 Kordes, S, Romero-Romero, S, Hocker, B. 登録日 2021-06-09 公開日 2021-12-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
5EZ8	A de novo designed heptameric coiled coil CC-Hept-I-C-I 分子名称: CC-Hept-I-C-I 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-11-26 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZE	A de novo designed heptameric coiled coil CC-Hept-I18betaMeCys-L22H-I25E 分子名称: CC-Hept-bMeCys-His-Glu, GLYCEROL 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-11-26 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZ9	A de novo designed heptameric coiled coil CC-Hept-I-H-I 分子名称: CC-Hept-L22H, HEXANE-1,6-DIOL 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-11-26 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5F2Y	A de novo designed heptameric coiled coil CC-Hept-homoCys-H-E 分子名称: CC-Hept-hCys-H-E 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-12-02 公開日 2016-07-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZA	A de novo designed heptameric coiled coil CC-Hept-I18C-L22H 分子名称: CC-Hept-C-H-I, GLYCEROL 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-11-26 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZC	A de novo designed heptameric coiled coil CC-Hept-I18C-L22H-I25E 分子名称: CC-Hept-C-H-E 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-11-26 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5JI4	Solution structure of the de novo mini protein gEEHE_02 分子名称: W37 著者 Buchko, G.W, Bahl, C.D, Pulavarti, S.V, Baker, D, Szyperski, T. 登録日 2016-04-21 公開日 2016-09-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
5TX8	Solution structure of the de novo mini protein gHH_44 分子名称: HH2 著者 Buchko, G.W, Bahl, C.D, Baker, D. 登録日 2016-11-15 公開日 2017-09-27 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides. Protein Sci., 27, 2018
7BIM	A de novo designed nonameric coiled coil, CC-Type2-(GgLaId)4 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Nonameric de novo coiled coil CC-Type2-(GgLaId)4 著者 Shelley, K.L, Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2021-01-12 公開日 2021-04-21 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
6W70	Crystal Structure of apixaban-bound ABLE 分子名称: 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDINE-3-CARBOXAMIDE, ACETATE ION, De novo designed ABLE, ... 著者 Polizzi, N.F. 登録日 2020-03-18 公開日 2020-08-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.296 Å) 主引用文献 A defined structural unit enables de novo design of small-molecule-binding proteins. Science, 369, 2020
6W6X	Crystal Structure of ABLE Apo-protein 分子名称: ACETATE ION, De novo designed ABLE protein, SULFATE ION 著者 Polizzi, N.F. 登録日 2020-03-18 公開日 2020-08-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.297 Å) 主引用文献 A defined structural unit enables de novo design of small-molecule-binding proteins. Science, 369, 2020
5EON	Crystal structure of a de novo antiparallel coiled-coil hexamer - ACC-Hex 分子名称: ACC-Hex 著者 Spencer, R.K, Hochbaum, A.I. 登録日 2015-11-10 公開日 2016-05-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.696 Å) 主引用文献 X-ray Crystallographic Structure and Solution Behavior of an Antiparallel Coiled-Coil Hexamer Formed by de Novo Peptides. Biochemistry, 55, 2016
5JHI	Solution structure of the de novo mini protein gEHE_06 分子名称: W35 著者 Buchko, G.W, Bahl, C.D, Gilmore, J.M, Pulavarti, S.V, Baker, D, Szyperski, T. 登録日 2016-04-21 公開日 2016-09-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
7NFK	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24S. 分子名称: CC-Type2-(LaId)4-I24S, ISOPROPYL ALCOHOL 著者 Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2021-02-07 公開日 2022-03-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFH	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(MaId)4. 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CC-Type2-(MaId)4 著者 Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2021-02-07 公開日 2022-03-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFL	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24N. 分子名称: CC-Type2-(LaId)4-I24N 著者 Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2021-02-07 公開日 2022-03-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023

<12345678910111213141516>