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9AX7
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70S initiation complex (tRNA-fMet M1 + CUG start codon)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Mattingly, J.M, Nguyen, H.A, Dunham, C.M.
登録日2024-03-06
公開日2024-09-18
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献Structural analysis of noncanonical translation initiation complexes.
J.Biol.Chem., 300, 2024
9DR5
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Crystal structure of Catechol 1,2-dioxygenase from Burkholderia multivorans (Zinc bound, P1 form)
分子名称: ACETATE ION, Catechol 1,2-dioxygenase, DI(HYDROXYETHYL)ETHER, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-09-25
公開日2024-10-02
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Crystal structure of Catechol 1,2-dioxygenase from Burkholderia multivorans (Zinc bound, P1 form)
To be published
9BLN
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The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex
分子名称: 40S ribosomal protein S14, ACETIC ACID, Eukaryotic initiation factor 4A-I, ...
著者Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Zuber, P, Yifei, D, Albacete-Albacete, L, Ramakrishnan, V, S Fraser, C.
登録日2024-04-30
公開日2024-09-04
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.
Nat Commun, 15, 2024
9BOQ
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Human p97/VCP structure with a triazole inhibitor (NSC799462/dodecamer)
分子名称: 3-(2,6-difluoro-4-{[(4P)-5-{[(2S)-hexan-2-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Nandi, P, DeVore, K, Chiu, P.-L.
登録日2024-05-05
公開日2024-08-21
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Mechanism of allosteric inhibition of human p97/VCP ATPase and its disease mutant by triazole inhibitors.
Commun Chem, 7, 2024
8Y4A
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BA.2.86 S-trimer in complex with Nab XG2v046
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Zhu, Q, Liu, P.
登録日2024-01-30
公開日2024-09-11
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Enhancing RBD exposure and S1 shedding by an extremely conserved SARS-CoV-2 NTD epitope.
Signal Transduct Target Ther, 9, 2024
9CGM
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The Structure of Spiroplasma Virus 4
分子名称: Capsid protein VP1, DNA binding protein ORF8
著者Mietzsch, M, McKenna, R.
登録日2024-06-30
公開日2024-07-17
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献The Structure of Spiroplasma Virus 4 : Exploring the Capsid Diversity of the Microviridae.
Viruses, 16, 2024
9F40
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BU of 9f40 by Molmil
Crystal structure of the NTD domain from S. cerevisia Niemann-Pick type C protein NCR1 with ergosterol bound
分子名称: ACETONITRILE, DI(HYDROXYETHYL)ETHER, ERGOSTEROL, ...
著者Nel, L, Olesen, E, Frain, K.M, Pedersen, B.P.
登録日2024-04-26
公開日2024-05-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural and biochemical analysis of ligand binding in yeast Niemann-Pick type C 1-related protein
To Be Published
9F9Y
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SARS-CoV-2 BA-2.87.1 Spike ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin
著者Ren, J, Stuart, D.I, Duyvesteyn, H.M.E.
登録日2024-05-09
公開日2024-08-21
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Concerted deletions eliminate a neutralizing supersite in SARS-CoV-2 BA.2.87.1 spike.
Structure, 32, 2024
9FO3
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Structure of a gp140 SpyTag-SpyCatcher mi3 nanoparticle including mi3 density only.
分子名称: CAP255 gp140 SpyTag-SpyCatcher mi3,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase
著者Woodward, J.D, Malebo, K, Chapman, R.
登録日2024-06-11
公開日2024-10-09
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Development of a Two-Component Nanoparticle Vaccine Displaying an HIV-1 Envelope Glycoprotein that Elicits Tier 2 Neutralising Antibodies.
Vaccines (Basel), 12, 2024
9EZL
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BU of 9ezl by Molmil
Crystal structure of trehalose synthase mutant N253H from Deinococcus radiodurans
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, MAGNESIUM ION, ...
著者Ye, L.C, Chen, S.C.
登録日2024-04-12
公開日2024-09-04
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural and Mutational Analyses of Trehalose Synthase from Deinococcus radiodurans Reveal the Interconversion of Maltose-Trehalose Mechanism.
J.Agric.Food Chem., 72, 2024
9CWS
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BU of 9cws by Molmil
Bufavirus 1 at pH 2.6
分子名称: VP1
著者Gulkis, M.C, McKenna, R, Bennett, A.D.
登録日2024-07-30
公開日2024-08-21
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes.
Viruses, 16, 2024
9C6W
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BU of 9c6w by Molmil
Crystal Structure of a single chain trimer composed of HLA-B*39:06 Y84C variant, beta-2microglobulin, and NRVMLPKAA peptide from NLRP2 (2 molecules/asymmetric unit)
分子名称: 1,2-ETHANEDIOL, 3,6,9,12,15-PENTAOXAHEPTADECANE, CHLORIDE ION, ...
著者Sharma, R, Amdare, N.P, Celikgil, A, Garforth, S.J, DiLorenzo, T.P, Almo, S.C, Ghosh, A.
登録日2024-06-09
公開日2024-09-04
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and biochemical analysis of highly similar HLA-B allotypes differentially associated with type 1 diabetes.
J.Biol.Chem., 300, 2024
9ES9
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Cryo-EM structure of Spinacia oleracea cytochrome b6f complex with inhibitor DBMIB bound at plastoquinol oxidation site
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,5-DIBROMO-3-ISOPROPYL-6-METHYLBENZO-1,4-QUINONE, ...
著者Pietras, R, Pintscher, S, Mielecki, B, Szwalec, M, Wojcik-Augustyn, A, Indyka, P, Rawski, M, Koziej, L, Jaciuk, M, Wazny, G, Glatt, S, Osyczka, A.
登録日2024-03-25
公開日2024-10-16
実験手法ELECTRON MICROSCOPY (2.33 Å)
主引用文献Molecular basis of plastoquinone reduction in plant cytochrome b 6 f.
Nat.Plants, 2024
9GGJ
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BU of 9ggj by Molmil
Crystal structure of argininosuccinate lyase from Arabidopsis thaliana (AtASL) in complex with biological substrate and products - argininosuccinate, argnine and fumarate
分子名称: ARGININE, ARGININOSUCCINATE, Argininosuccinate lyase, ...
著者Nielipinski, M, Pietrzyk-Brzezinska, A.J, Krzeszewska, D, Sekula, B.
登録日2024-08-13
公開日2024-10-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Arabidopsis thaliana argininosuccinate lyase structure uncovers the role of serine as the catalytic base.
J.Struct.Biol., 216, 2024
9FSV
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BU of 9fsv by Molmil
Yeast 20S proteasome with human beta2i (1-53) in complex with epoxyketone inhibitor 42
分子名称: (2S)-N-[(2S)-1-[[(1S)-2-cyclohexyl-1-[(2R,3S,6R,7S)-3-methanoyl-2,6-dimethyl-6,7-bis(oxidanyl)-1,4-oxazepan-7-yl]ethyl]amino]-3-(4-methoxyphenyl)-1-oxidanylidene-propan-2-yl]-2-(2-morpholin-4-ylethanoylamino)-4-oxidanyl-butanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Maurits, E, Huber, E.M, Dekker, P.M, Wang, X, Heinemeyer, W, Florea, B.I, Groll, M, Overkleeft, H.S.
登録日2024-06-22
公開日2024-07-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites
to be published
9GBK
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BU of 9gbk by Molmil
Blm10-20S proteasome complex from pre1-1
分子名称: Probable proteasome subunit alpha type-7, Proteasome activator BLM10, Proteasome subunit alpha type-1, ...
著者Mark, E, Ramos, P.C, Kayser, F, Hoeckendorff, J, Dohmen, R.J, Wendler, P.
登録日2024-07-31
公開日2024-09-11
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Structural roles of Ump1 and beta-subunit propeptides in proteasome biogenesis.
Life Sci Alliance, 7, 2024
9B45
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BU of 9b45 by Molmil
Pseudomonas phage Pa193 baseplate complex and tail fiber
分子名称: gp34 helical bundle, gp35 Sheath initiator, gp37 Baseplate tube, ...
著者Iglesias, S.M, Cingolani, G.
登録日2024-03-20
公開日2024-10-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM analysis of Pseudomonas phage Pa193 structural components.
Commun Biol, 7, 2024
9AXN
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BU of 9axn by Molmil
Crystal Structure of Anti-Fentanyl Antibody HY11-6B2_Mu Fab in Complex with Fentanyl
分子名称: 1,2-ETHANEDIOL, HY11-6B2_Mu Fab Heavy Chain, HY11-6B2_Mu Fab Light Chain, ...
著者Rodarte, J.V, Pancera, M.
登録日2024-03-06
公開日2024-10-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based engineering of monoclonal antibodies against fentanyl and carfentanil for improved binding
To Be Published
9GCT
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BU of 9gct by Molmil
Rho-ATP-Psu complex II expanded
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polarity suppression protein, ...
著者Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B.
登録日2024-08-02
公開日2024-10-09
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Rho-ATP-Psu complex II expanded
To Be Published
9B8O
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BU of 9b8o by Molmil
Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3, Vo
分子名称: (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Coupland, C.E, Rubinstein, J.L.
登録日2024-03-31
公開日2024-06-26
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献High-resolution electron cryomicroscopy of V-ATPase in native synaptic vesicles.
Science, 385, 2024
9JER
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BU of 9jer by Molmil
Arginine decarboxylase in Aspergillus oryzae, ligand-free form
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, L-tryptophan decarboxylase PsiD-like domain-containing protein
著者Mikami, B, Yasukawa, K, Fujiwara, S, Takita, T, Mizutani, K, Odagaki, Y, Murakami, Y.
登録日2024-09-03
公開日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Unveiling the reaction mechanism of arginine decarboxylase in Aspergillus oryzae: Insights from crystal structure analysis.
Biochem.Biophys.Res.Commun., 733, 2024
8AQ6
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BU of 8aq6 by Molmil
NanoLuc luciferase with bound furimamide in surface allosteric site
分子名称: CHLORIDE ION, GLYCEROL, N-(3-Benzyl-5-phenylpyrazin-2-yl)-2-(furan-2-yl)acetamide, ...
著者Nemergut, M, Marek, M.
登録日2022-08-11
公開日2023-08-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023
5MFD
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BU of 5mfd by Molmil
Designed armadillo repeat protein YIIIM''6AII in complex with pD_(KR)5
分子名称: CALCIUM ION, Capsid decoration protein,pD_(KR)5, YIIIM''6AII
著者Hansen, S, Kiefer, J, Madhurantakam, C, Mittl, P, Plueckthun, A.
登録日2016-11-18
公開日2017-07-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of designed armadillo repeat proteins binding to peptides fused to globular domains.
Protein Sci., 26, 2017
2LMA
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BU of 2lma by Molmil
Solution structure of CD4+ T cell derived peptide Thp5
分子名称: Thp5 peptide
著者Pandey, N.K, Khan, M.M, Chatterjee, S, Dwivedi, V.P, Tousif, S, Das, J, Van Kaer, L.
登録日2011-11-29
公開日2011-12-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献CD4+ T cell derived novel peptide Thp5 induces IL-4 production in CD4+ T cells to direct T helper 2 cell differentiation
J.Biol.Chem., 2011
6R95
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BU of 6r95 by Molmil
The solution NMR structure of cis-dicarba-brevinin-1BYa in 33% trifluoroethanol
分子名称: Brevinin-1BYa
著者Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M.
登録日2019-04-02
公開日2019-09-25
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides.
Eur.Biophys.J., 48, 2019

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件を2024-10-30に公開中

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