PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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1CEL	THE THREE-DIMENSIONAL CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF CELLOBIOHYDROLASE I FROM TRICHODERMA REESEI 分子名称: 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-IODOBENZYLTHIO GROUP, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Divne, C, Jones, T.A. 登録日 1994-05-17 公開日 1994-11-01 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The three-dimensional crystal structure of the catalytic core of cellobiohydrolase I from Trichoderma reesei. Science, 265, 1994
5DLW	Crystal structure of Autotaxin (ENPP2) with tauroursodeoxycholic acid (TUDCA) and lysophosphatidic acid (LPA) 分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, 2-{[(3alpha,5beta,7alpha,8alpha,14beta,17alpha)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid, CALCIUM ION, ... 著者 Keune, W.J, Heidebrecht, T, Joosten, R.P, Perrakis, A. 登録日 2015-09-07 公開日 2016-04-13 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. Nat Commun, 7, 2016
6HVJ	Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 3 分子名称: 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, 8-(3-methyl-1-benzofuran-5-yl)-~{N}-(4-methylsulfonylpyridin-3-yl)quinoxalin-6-amine, ... 著者 Banaszak, K, Pawlik, H, Bialas, A, Fabritius, C.H, Nowak, M. 登録日 2018-10-11 公開日 2018-11-14 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Discovery and Structure-Activity Relationships of N-Aryl 6-Aminoquinoxalines as Potent PFKFB3 Kinase Inhibitors. ChemMedChem, 14, 2019
3WAX	Crystal Structure of Autotaxin in Complex with 3BoA 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.899 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
3WAY	Crystal Structure of Autotaxin in Complex with 4BoA 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.746 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
3WAV	Crystal Structure of Autotaxin in Complex with Compound 10 分子名称: (5Z)-5-(3,4-dichlorobenzylidene)-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4(5H)-one, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.797 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
6CVB	CryoEM structure of human enterovirus D68 in complex with 6'-sialyl-N-acetyllactosamine 分子名称: N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, viral protein 1, viral protein 2, ... 著者 Liu, Y, Rossmann, M.G. 登録日 2018-03-27 公開日 2019-07-24 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2.43 Å) 主引用文献 Bypassing pan-enterovirus host factor PLA2G16. Nat Commun, 10, 2019
4UAF	Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain 分子名称: Importin subunit alpha-1, PHOSPHATE ION, Polymerase basic protein 2 著者 Pumroy, R.A, Cingolani, G. 登録日 2014-08-08 公開日 2015-02-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7. Structure, 23, 2015
4TVE	Structure Of the First Two Thioredoxin Domains of Naumovozyma dairenensis Eps1p 分子名称: Naumovozyma dairenensis Eps1p 著者 Deborah, F, Biran, S. 登録日 2014-06-26 公開日 2014-12-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The eps1p protein disulfide isomerase conserves classic thioredoxin superfamily amino Acid motifs but not their functional geometries. Plos One, 9, 2014
4TWI	The structure of Sir2Af1 bound to a succinylated histone peptide 分子名称: GLYCEROL, NAD-dependent protein deacylase 1, Succinylated H4 Peptide (aa8-20), ... 著者 Ringel, A.E, Roman, C, Wolberger, C. 登録日 2014-06-30 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Alternate deacylating specificities of the archaeal sirtuins Sir2Af1 and Sir2Af2. Protein Sci., 23, 2014
4TXD	Crystal structure of Thermofilum pendens Csc2 分子名称: Csc2, ZINC ION 著者 Hrle, A, Conti, E. 登録日 2014-07-03 公開日 2014-08-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.818 Å) 主引用文献 Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. Rna Biol., 11, 2014
4TY9	An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline 分子名称: 5-(trifluoromethyl)pyridin-2-amine, Polyprotein 著者 Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. 登録日 2014-07-08 公開日 2015-05-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
4TZF	Structure of metallo-beta lactamase 分子名称: NDM-8 metallo-beta-lactamase, ZINC ION 著者 Ferguson, J.A, Makena, A, Brem, J, McDonough, M.A, Schofield, C.J. 登録日 2014-07-10 公開日 2015-07-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 structure of metallo-beta lactamase To Be Published
4TZS	Structure of C. elegans HTP-2 bound to HIM-3 closure motif, P212121 form 分子名称: C. elegans HIM-3 closure motif, Protein HTP-2 著者 Rosenberg, S.C, Corbett, K.D. 登録日 2014-07-10 公開日 2014-11-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins. Dev.Cell, 31, 2014
4TUM	Crystal structure of Ankyrin Repeat Domain of AKR2 分子名称: Ankyrin repeat domain-containing protein 2 著者 Gwon, G.H, Cho, Y. 登録日 2014-06-24 公開日 2014-09-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 An Ankyrin Repeat Domain of AKR2 Drives Chloroplast Targeting through Coincident Binding of Two Chloroplast Lipids. Dev.Cell, 30, 2014
4U02	Crystal structure of apo-TTHA1159 分子名称: Amino acid ABC transporter, ATP-binding protein, SULFATE ION 著者 Karthiga Devi, S, Chichili, V.P.R, Velmurugan, D, Sivaraman, J. 登録日 2014-07-11 公開日 2015-05-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Structural basis for the hydrolysis of ATP by a nucleotide binding subunit of an amino acid ABC transporter from Thermus thermophilus J.Struct.Biol., 190, 2015
6OIL	Crystal structure of human VISTA extracellular domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, V-type immunoglobulin domain-containing suppressor of T-cell activation 著者 Mehta, N, Cochran, J.R, Mathews, I.I. 登録日 2019-04-09 公開日 2019-09-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure and Functional Binding Epitope of V-domain Ig Suppressor of T Cell Activation. Cell Rep, 28, 2019
4TUY	Tubulin-Rhizoxin complex 分子名称: (1R,2R,3E,5R,7R,8S,10S,13E,16R)-8-hydroxy-10-[(2S,3R,4E,6E,8E)-3-methoxy-4,8-dimethyl-9-(2-methyl-1,3-oxazol-4-yl)nona-4,6,8-trien-2-yl]-2,7-dimethyl-6,11,19-trioxatricyclo[14.3.1.0~5,7~]icosa-3,13-diene-12,18-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Prota, A.E, Bargsten, K, Diaz, J.F, Marsh, M, Cuevas, C, Liniger, M, Neuhaus, C, Andreu, J.M, Altmann, K.H, Steinmetz, M.O. 登録日 2014-06-25 公開日 2014-08-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs. Proc.Natl.Acad.Sci.USA, 111, 2014
7NCB	Glutathione-S-transferase GliG mutant H26A 分子名称: Glutathione S-transferase GliG 著者 Groll, M, Huber, E.M. 登録日 2021-01-28 公開日 2021-05-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
4TVT	New ligand for thaumatin discovered using acoustic high throughput screening 分子名称: ASCORBIC ACID, L(+)-TARTARIC ACID, SODIUM ION, ... 著者 Teplitsky, E, Joshi, K, Ericson, D.L, Scalia, A, Mullen, J.D, Sweet, R.M, Soares, A.S. 登録日 2014-06-28 公開日 2014-07-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 High throughput screening using acoustic droplet ejection to combine protein crystals and chemical libraries on crystallization plates at high density. J.Struct.Biol., 191, 2015
7NC9	Glutathione-S-transferase GliG mutant H26N 分子名称: 1,2-ETHANEDIOL, Glutathione S-transferase GliG 著者 Groll, M, Huber, E.M. 登録日 2021-01-28 公開日 2021-05-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
7NCM	Glutathione-S-transferase GliG mutant E82A 分子名称: 1,2-ETHANEDIOL, Glutathione S-transferase GliG 著者 Groll, M, Huber, E.M. 登録日 2021-01-29 公開日 2021-05-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
4TVY	Apo resorufin ligase 分子名称: 5-(3,7-dihydroxy-10H-phenoxazin-2-yl)pentanamide, Lipoate-protein ligase A 著者 Goldman, P.J, Drennan, C.L. 登録日 2014-06-28 公開日 2014-10-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Computational design of a red fluorophore ligase for site-specific protein labeling in living cells. Proc.Natl.Acad.Sci.USA, 111, 2014
7NCU	Glutathione-S-transferase GliG mutant K127G in complex with oxidized glutathione 分子名称: 1,2-ETHANEDIOL, Glutathione S-transferase GliG, OXIDIZED GLUTATHIONE DISULFIDE 著者 Groll, M, Huber, E.M. 登録日 2021-01-29 公開日 2021-05-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
7NCT	Glutathione-S-transferase GliG mutant K127G 分子名称: Glutathione S-transferase GliG 著者 Groll, M, Huber, E.M. 登録日 2021-01-29 公開日 2021-05-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021

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