Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8UQZ
DownloadVisualize
BU of 8uqz by Molmil
Round 18 Arylesterase Variant of Phosphotriesterase Bound to Gadolinium(III) Measured at 9.5 keV
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, GADOLINIUM ION, ...
著者Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J.
登録日2023-10-25
公開日2024-04-03
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase.
Acta Crystallogr D Struct Biol, 80, 2024
1YWH
DownloadVisualize
BU of 1ywh by Molmil
crystal structure of urokinase plasminogen activator receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Llinas, P, Le Du, M.H, Gardsvoll, H, Dano, K, Ploug, M, Gilquin, B, Stura, E.A, Menez, A.
登録日2005-02-18
公開日2005-05-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide
EMBO J., 24, 2005
8UUU
DownloadVisualize
BU of 8uuu by Molmil
SARS-Cov-2 papain-like protease (PLpro) with inhibitor Jun12162
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Ansari, A, Tan, B, Ruiz, F.X, Arnold, E, Wang, J.
登録日2023-11-02
公開日2024-04-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model.
Science, 383, 2024
5MRG
DownloadVisualize
BU of 5mrg by Molmil
Solution structure of TDP-43 (residues 1-102)
分子名称: TAR DNA-binding protein 43
著者Mompean, M, Romano, V, Pantoja-Uceda, D, Stuani, C, Baralle, F.E, Laurents, D.V.
登録日2016-12-22
公開日2017-06-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions.
J. Biol. Chem., 292, 2017
6NRP
DownloadVisualize
BU of 6nrp by Molmil
Putative short-chain dehydrogenase/reductase (SDR) from Acinetobacter baumannii
分子名称: 3-oxoacyl-ACP reductase FabG
著者Cross, E.M, Smith, K.M, Shaw, K.I, Aragao, D, Forwood, J.K.
登録日2019-01-23
公開日2019-02-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases.
Sci Rep, 11, 2021
6S0G
DownloadVisualize
BU of 6s0g by Molmil
Crystal structure of ene-reductase GsOYE from Galdieria sulphuraria
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Robescu, M.R, Niero, M, Hall, M, Bergantino, E, Cendron, L.
登録日2019-06-14
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Two new ene-reductases from photosynthetic extremophiles enlarge the panel of old yellow enzymes: CtOYE and GsOYE.
Appl.Microbiol.Biotechnol., 104, 2020
6CHN
DownloadVisualize
BU of 6chn by Molmil
Phosphopantetheine adenylyltransferase (CoaD) in complex with methyl (R)-4-(3-(2-cyano-1-((5-methyl-7-oxo-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)amino)ethyl)phenoxy)piperidine-1-carboxylate
分子名称: DI(HYDROXYETHYL)ETHER, Phosphopantetheine adenylyltransferase, SULFATE ION, ...
著者Mamo, M, Appleton, B.A.
登録日2018-02-22
公開日2018-04-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity.
J. Med. Chem., 61, 2018
6S0Z
DownloadVisualize
BU of 6s0z by Molmil
Erythromycin Resistant Staphylococcus aureus 50S ribosome (delta R88 A89 uL22) in complex with erythromycin.
分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A.
登録日2019-06-18
公開日2019-08-21
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Sci Rep, 9, 2019
2VO2
DownloadVisualize
BU of 2vo2 by Molmil
Crystal structure of soybean ascorbate peroxidase mutant W41A subjected to low dose X-rays
分子名称: ASCORBATE PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ...
著者Metcalfe, C.L, Badyal, S.K, Raven, E.L, Moody, P.C.E.
登録日2008-02-08
公開日2008-04-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Iron Oxidation State Modulates Active Site Structure in a Heme Peroxidase.
Biochemistry, 47, 2008
1ZBA
DownloadVisualize
BU of 1zba by Molmil
Foot-and-Mouth Disease virus serotype A1061 complexed with oligosaccharide receptor.
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Coat protein VP1, Coat protein VP2, ...
著者Fry, E.E, Newman, J.W, Curry, S, Najjam, S, Jackson, T, Blakemore, W, Lea, S.M, Miller, L, Burman, A, King, A.M, Stuart, D.I.
登録日2005-04-08
公開日2005-06-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Foot-and-mouth disease virus serotype A1061 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation.
J.Gen.Virol., 86, 2005
1CCL
DownloadVisualize
BU of 1ccl by Molmil
PROBING THE STRENGTH AND CHARACTER OF AN ASP-HIS-X HYDROGEN BOND BY INTRODUCING BURIED CHARGES
分子名称: CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
著者Cao, Y, Goodin, D.B, Mcree, D.E.
登録日1998-01-02
公開日1998-11-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the Strength and Character of an Asp-His-X Hydrogen Bond by Introducing Buried Charges
To be Published
3J34
DownloadVisualize
BU of 3j34 by Molmil
Structure of HIV-1 Capsid Protein by Cryo-EM
分子名称: capsid protein
著者Zhao, G, Perilla, J.R, Yufenyuy, E, Meng, X, Chen, B, Ning, J, Ahn, J, Gronenborn, A.M, Schulten, K, Aiken, C, Zhang, P.
登録日2013-02-23
公開日2013-05-29
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
6CCV
DownloadVisualize
BU of 6ccv by Molmil
Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Rifampicin
分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ...
著者Lilic, M, Darst, S.A, Campbell, E.A.
登録日2018-02-07
公開日2018-08-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
8UQX
DownloadVisualize
BU of 8uqx by Molmil
Round 18 Arylesterase Variant of Apo-Phosphotriesterase Measured at 9.5 keV
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphotriesterase variant PTE-R18
著者Breeze, C.W, Frkic, R.L, Campbell, E.C, Jackson, C.J.
登録日2023-10-25
公開日2024-04-03
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase.
Acta Crystallogr D Struct Biol, 80, 2024
1NA4
DownloadVisualize
BU of 1na4 by Molmil
The structure of immature Yellow Fever virus particle
分子名称: major envelope protein E
著者Zhang, Y, Corver, J, Chipman, P.R, Lenches, E, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G.
登録日2002-11-26
公開日2003-12-09
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY
主引用文献Structures of immature flavivirus particles
EMBO J., 22, 2003
8V84
DownloadVisualize
BU of 8v84 by Molmil
60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map)
分子名称: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
登録日2023-12-04
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
2ATP
DownloadVisualize
BU of 2atp by Molmil
Crystal structure of a CD8ab heterodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, ...
著者Chang, H.C, Tan, K, Ouyang, J, Parisini, E, Liu, J.H, Le, Y, Wang, X, Reinherz, E.L, Wang, J.H.
登録日2005-08-25
公開日2005-12-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Mutational Analyses of a CD8alphabeta Heterodimer and Comparison with the CD8alphaalpha Homodimer.
Immunity, 23, 2005
3ZXW
DownloadVisualize
BU of 3zxw by Molmil
STRUCTURE OF ACTIVATED RUBISCO FROM THERMOSYNECHOCOCCUS ELONGATUS COMPLEXED WITH 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE
分子名称: 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Terlecka, B, Wilhelmi, V, Bialek, W, Gubernator, B, Szczepaniak, A, Hofmann, E.
登録日2011-08-16
公開日2012-08-29
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of Ribulose-1,5-Bisphosphate Carboxylase Oxygenase from Thermosynechococcus Elongatus
To be Published
7RPR
DownloadVisualize
BU of 7rpr by Molmil
Borrelia miyamotoi FbpA complement inhibitory domain
分子名称: Fibronectin-binding lipoprotein FbpA
著者Booth, C.E, Garcia, B.L.
登録日2021-08-04
公開日2022-04-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Borrelia miyamotoi FbpA and FbpB Are Immunomodulatory Outer Surface Lipoproteins With Distinct Structures and Functions.
Front Immunol, 13, 2022
3E1P
DownloadVisualize
BU of 3e1p by Molmil
Crystal structure of E. coli Bacterioferritin (BFR) in which the Ferroxidase centre is inhibited with ZN(II) and high occupancy iron is bound within the cavity.
分子名称: BACTERIOFERRITIN, FE (II) ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Crow, A, Lawson, T, Lewin, A, Moore, G.R, Le Brun, N.
登録日2008-08-04
公開日2009-05-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for iron mineralization by bacterioferritin
J.Am.Chem.Soc., 131, 2009
6NFY
DownloadVisualize
BU of 6nfy by Molmil
Crystal structure of nonphosphorylated, HPK1 kinase domain in complex with sunitinib in the inactive state.
分子名称: Mitogen-activated protein kinase kinase kinase kinase 1, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide
著者Johnson, E, McTigue, M, Cronin, C.N.
登録日2018-12-21
公開日2019-05-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation.
J.Biol.Chem., 294, 2019
3N01
DownloadVisualize
BU of 3n01 by Molmil
Crystal structure of an abridged form of the mature ectodomain of the Human Receptor-Type Protein Tyrosine Phosphatase ICA512/IA-2 at pH 8.5
分子名称: CALCIUM ION, Receptor-type tyrosine-protein phosphatase-like N
著者Primo, M.E, Jakoncic, J, Poskus, E, Ermacora, M.R.
登録日2010-05-13
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Receptor-type Protein-Tyrosine Phosphatase IA-2-ICA512
To be Published
8UVM
DownloadVisualize
BU of 8uvm by Molmil
SARS-CoV-2 papain-like protease (PLpro) complex with covalent inhibitor Jun11313
分子名称: CHLORIDE ION, Papain-like protease nsp3, SULFATE ION, ...
著者Ansari, A, Tan, B, Chopra, A, Ruiz, F.X, Arnold, E, Wang, J.
登録日2023-11-03
公開日2024-04-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model.
Science, 383, 2024
3ZD4
DownloadVisualize
BU of 3zd4 by Molmil
Full-Length Hammerhead Ribozyme with G12A substitution at the general base position
分子名称: HAMMERHEAD RIBOZYME, ENZYME STRAND, SUBSTRATE STRAND
著者Scott, W.G, Schultz, E.
登録日2012-11-24
公開日2012-12-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Catalytic Effects of an Invariant Purine Substitution in the Hammerhead Ribozyme: Implications for the Mechanism of Acid-Base Catalysis.
Acta Crystallogr.,Sect.D, 70, 2014
7LDY
DownloadVisualize
BU of 7ldy by Molmil
HIV-1 Protease WT (NL4-3) in Complex with TMC-126
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL [(1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL]CARBAMATE, Protease, SULFATE ION
著者Lockbaum, G.J, Rusere, L.N, Henes, M, Kosovrasti, K, Lee, S.K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A.
登録日2021-01-14
公開日2022-07-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.984 Å)
主引用文献HIV-1 Protease Inhibitors with a P1 Phosphonate Modification Maintain Potency against Drug Resistant Variants by Increased van der Waals Contacts with Flaps Residues
To Be Published

224004

件を2024-08-21に公開中

PDB statisticsPDBj update infoContact PDBjnumon