PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

---

7N0V	Complex of recombinant Bet v 1 with Fab fragment of REGN5715 分子名称: Major pollen allergen Bet v 1-A, REGN5715 Fab heavy chain, REGN5715 Fab light chain 著者 Franklin, M.C, Romero Hernandez, A. 登録日 2021-05-26 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.71 Å) 主引用文献 Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response. J.Allergy Clin.Immunol., 149, 2022
6XPX	Human antibody S1V2-51 in complex with the influenza hemagglutinin head domain of A/Aichi/2/1968 (X-31)(H3N2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICINE, GLYCEROL, ... 著者 McCarthy, K.R, Harrison, S.C. 登録日 2020-07-09 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.598 Å) 主引用文献 A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface. Mbio, 12, 2021
6XPY	Human antibody S1V2-58 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2) 分子名称: Fab heavy chain, Fab light chain, Hemagglutinin, ... 著者 McCarthy, K.R, Harrison, S.C. 登録日 2020-07-09 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.603 Å) 主引用文献 A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface. Mbio, 12, 2021
7MYH	Ubiquitin variant UbV.k.2 in complex with Ube2k 分子名称: GLYCEROL, Ubiquitin variant UbV.k.2, Ubiquitin-conjugating enzyme E2 K 著者 Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S. 登録日 2021-05-21 公開日 2021-08-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.394 Å) 主引用文献 Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k. Acs Chem.Biol., 16, 2021
4YS2	RCK domain with CDA 分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Na+/H+ antiporter-like protein 著者 Chin, K.H, Chou, S.H. 登録日 2015-03-16 公開日 2016-04-27 最終更新日 2020-02-05 実験手法 X-RAY DIFFRACTION (1.968 Å) 主引用文献 RCK domain with CDA To Be Published
6XKD	Structure of ligand-bound mouse cGAMP hydrolase ENPP1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Fernandez, D, Li, L. 登録日 2020-06-26 公開日 2021-06-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiesterase of the Immunotransmitter cGAMP. Cell Chem Biol, 27, 2020
4YTW	Crystal structure of Ups1-Mdm35 complex 分子名称: Mitochondrial distribution and morphology protein 35, Protein UPS1, mitochondrial 著者 Watanabe, Y, Tamura, Y, Kawano, S, Endo, T. 登録日 2015-03-18 公開日 2015-08-12 最終更新日 2020-02-05 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural and mechanistic insights into phospholipid transfer by Ups1-Mdm35 in mitochondria. Nat Commun, 6, 2015
1A47	CGTASE FROM THERMOANAEROBACTERIUM THERMOSULFURIGENES EM1 IN COMPLEX WITH A MALTOHEXAOSE INHIBITOR 分子名称: 1-AMINO-2,3-DIHYDROXY-5-HYDROXYMETHYL CYCLOHEX-5-ENE, CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, ... 著者 Uitdehaag, J.C.M, Kalk, K.H, Rozeboom, H.J, Dijkstra, B.W. 登録日 1998-02-11 公開日 1998-06-17 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Engineering of cyclodextrin product specificity and pH optima of the thermostable cyclodextrin glycosyltransferase from Thermoanaerobacterium thermosulfurigenes EM1. J.Biol.Chem., 273, 1998
4YTC	Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Disease 分子名称: N~3~-phenyl-1-[6-(phenylamino)pyrimidin-4-yl]-1H-1,2,4-triazole-3,5-diamine, Tyrosine-protein kinase JAK2 著者 Zuccola, H.J, Ledeboer, M. 登録日 2015-03-17 公開日 2015-08-12 最終更新日 2015-10-07 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases. J.Med.Chem., 58, 2015
4YTH	Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Diseases 分子名称: N~2~-[2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-2-methyl-N-(2,2,2-trifluoroethyl)-D-alaninamide, Tyrosine-protein kinase JAK2 著者 Ledeboer, M.W, Zuccola, H.J. 登録日 2015-03-17 公開日 2015-08-12 最終更新日 2016-07-20 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases. J.Med.Chem., 58, 2015
4YTO	Structure of coiled-coil domain of SYCP1 分子名称: GLYCEROL, Synaptonemal complex protein 1 著者 park, H.H. 登録日 2015-03-18 公開日 2016-03-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of coiled-coil domain of SYCP1 To Be Published
1AJ5	CALPAIN DOMAIN VI APO 分子名称: CALPAIN 著者 Cygler, M, Grochulski, P, Blanchard, H. 登録日 1997-05-15 公開日 1998-05-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes. Nat.Struct.Biol., 4, 1997
6WPO	NMR Structure of HSP-4 antimicrobial peptide in presence of DPC-d38 micelles 分子名称: Hylaseptin-4 著者 Verly, R.M, Nunes, L.O. 登録日 2020-04-27 公開日 2021-03-17 実験手法 SOLUTION NMR 主引用文献 High-resolution structural profile of hylaseptin-4: Aggregation, membrane topology and pH dependence of overall membrane binding process. Biochim Biophys Acta Biomembr, 1863, 2021
4YZS	Crystal structures reveal transient PERK luminal domain tetramerization in ER stress signaling 分子名称: Eukaryotic translation initiation factor 2-alpha kinase 3, TUNGSTEN ION 著者 Carrara, M, Prischi, F, Ali, M.M.U. 登録日 2015-03-25 公開日 2015-05-13 最終更新日 2017-09-13 実験手法 X-RAY DIFFRACTION (3.14 Å) 主引用文献 Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling. Embo J., 34, 2015
4YZO	Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii 分子名称: ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Padmanabhan, B, Manjula, R, Yokoyama, S, Bessho, Y. 登録日 2015-03-25 公開日 2016-03-30 最終更新日 2020-02-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii To Be Published
6WE7	HIV Integrase core domain in complex with inhibitor 3-methyl-2-{5-methyl-2-[2-(thiophen-2-yl)ethynyl]-1- benzofuran-3-yl}butanoic acid 分子名称: (2S)-3-methyl-2-{5-methyl-2-[(thiophen-2-yl)ethynyl]-1-benzofuran-3-yl}butanoic acid, IODIDE ION, Integrase, ... 著者 Gorman, M.A, Parker, M.W. 登録日 2020-04-01 公開日 2021-04-07 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 HIV Integrase core domain in complex with inhibitor To Be Published
7N4N	BACE-2 in complex with ligand 36 分子名称: 1,2-ETHANEDIOL, Beta-secretase 2, N-{3-[(2S,5R)-6-amino-2-(fluoromethyl)-5-(methanesulfonyl)-5-methyl-2,3,4,5-tetrahydropyridin-2-yl]-4-fluorophenyl}-6-methoxypyrimidine-4-carboxamide, ... 著者 Shaffer, P.L. 登録日 2021-06-04 公開日 2021-10-06 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate. J.Med.Chem., 64, 2021
4Z1H	Crystal structure of human Trap1 with SMTIN-P01 分子名称: 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[6-(triphenyl-lambda~5~-phosphanyl)hexyl]-9H-purin-6-amine, Heat shock protein 75 kDa, mitochondrial 著者 Lee, C, Park, H.K, Ryu, J.H, Kang, B.H. 登録日 2015-03-27 公開日 2015-04-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1 J.Am.Chem.Soc., 137, 2015
4YZI	Crystal structure of blue-shifted channelrhodopsin mutant (T198G/G202A) 分子名称: OLEIC ACID, RETINAL, Sensory opsin A,Archaeal-type opsin 2, ... 著者 Kato, H.E, Kamiya, M, Ishitani, R, Hayashi, S, Nureki, O. 登録日 2015-03-25 公開日 2015-05-27 最終更新日 2020-02-19 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Atomistic design of microbial opsin-based blue-shifted optogenetics tools. Nat Commun, 6, 2015
8S9B	Cryo-EM structure of Nav1.7 with LCM 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Fan, X, Huang, J, Yan, N. 登録日 2023-03-27 公開日 2023-08-30 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural mapping of Na v 1.7 antagonists. Nat Commun, 14, 2023
4Z05	C. bescii Family 3 pectate lyase mutant E84A 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... 著者 Alahuhta, P.M, Lunin, V.V. 登録日 2015-03-25 公開日 2015-12-23 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The catalytic mechanism and unique low pH optimum of Caldicellulosiruptor bescii family 3 pectate lyase. Acta Crystallogr.,Sect.D, 71, 2015
4Z3U	PRV nuclear egress complex 分子名称: CHLORIDE ION, SODIUM ION, UL31, ... 著者 Bigalke, J.M, Heldwein, E.E. 登録日 2015-03-31 公開日 2015-11-11 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (2.706 Å) 主引用文献 Structural basis of membrane budding by the nuclear egress complex of herpesviruses. Embo J., 34, 2015
8S9C	Cryo-EM structure of Nav1.7 with CBZ 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Fan, X, Huang, J, Yan, N. 登録日 2023-03-27 公開日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural mapping of Na v 1.7 antagonists. Nat Commun, 14, 2023
6WUX	NMR soltution structure of homotarsinin homodimer - Htr 分子名称: Homotarsinin 著者 Verly, R.M. 登録日 2020-05-05 公開日 2021-05-05 実験手法 SOLUTION NMR 主引用文献 Structure and membrane interactions of the homodimeric antibiotic peptide homotarsinin. Sci Rep, 7, 2017
4ZAM	Crystal structure of SHV-1 beta-lactamase bound to avibactam 分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE 著者 Krishnan, N, van den Akker, F. 登録日 2015-04-13 公開日 2016-01-27 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Inhibition of Klebsiella beta-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study. Plos One, 10, 2015

<732733734735736737738739740741742743744745746747>