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5W1V
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Structure of the HLA-E-VMAPRTLIL/GF4 TCR complex
分子名称: Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ...
著者Gras, S, Walpole, N, Farenc, C, Rossjohn, J.
登録日2017-06-04
公開日2017-10-04
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors.
J. Biol. Chem., 292, 2017
5T6W
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HLA-B*57:01 presenting SSTRGISQLW
分子名称: Beta-2-microglobulin, Decapeptide: SER-SER-THR-ARG-GLY-ILE-SER-GLN-LEU-TRP, GLYCEROL, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2016-09-01
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Nat. Struct. Mol. Biol., 24, 2017
1PY4
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BU of 1py4 by Molmil
Beta2 microglobulin mutant H31Y displays hints for amyloid formations
分子名称: Beta-2-microglobulin precursor
著者Rosano, C, Zuccotti, S, Mangione, P, Giorgetti, S, Bellotti, V, Pettirossi, F, Corazza, A, Viglino, P, Esposito, G, Bolognesi, M.
登録日2003-07-08
公開日2004-05-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation
J.Mol.Biol., 335, 2004
5T70
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BU of 5t70 by Molmil
KIR3DL1 in complex with HLA-B*57:01 presenting TSNLQEQIGW
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Decapeptide: THR-SER-ASN-LEU-GLN-GLU-GLN-ILE-GLY-TRP, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2016-09-02
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Nat. Struct. Mol. Biol., 24, 2017
5T6X
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HLA-B*57:01 presenting TSTTSVASSW
分子名称: Beta-2-microglobulin, Decapeptide: THR-SER-THR-THR-SER-VAL-ALA-SER-SER-TRP, GLYCEROL, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2016-09-02
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.686 Å)
主引用文献MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Nat. Struct. Mol. Biol., 24, 2017
4G8I
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BU of 4g8i by Molmil
Crystal Structure of HLA B2705-KK10-L6M
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, Gag protein, ...
著者Gras, S, Wilmann, P.G, Rossjohn, J.
登録日2012-07-23
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells.
Immunity, 38, 2013
4FTV
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BU of 4ftv by Molmil
The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide
分子名称: A6 alpha chain, A6 beta chain, Beta-2-microglobulin, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2012-06-28
公開日2013-07-03
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity
To be Published
4FXL
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Crystal structure of the D76N Beta-2 Microglobulin mutant
分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Ricagno, S, Bellotti, V, Pepys, M.B, Stoppini, M, Bolognesi, M.
登録日2012-07-03
公開日2012-08-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Hereditary systemic amyloidosis due to Asp76Asn variant beta-2-microglobulin.
N.Engl.J.Med., 366, 2012
4G8G
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BU of 4g8g by Molmil
Crystal Structure of C12C TCR-HA B2705-KK10
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ...
著者Gras, S, Wilmann, P.G, Rossjohn, J.
登録日2012-07-23
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells.
Immunity, 38, 2013
5VUD
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BU of 5vud by Molmil
HLA-B*57:01 presenting LSSPVTKSW
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-19
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
5W6A
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BU of 5w6a by Molmil
HLA-C*06:02 presenting ARTELYRSL
分子名称: ALA-ARG-THR-GLU-LEU-TYR-ARG-SER-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Mobbs, J.I, Vivian, J.P, Rossjohn, J.
登録日2017-06-16
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule.
J. Biol. Chem., 292, 2017
5V5L
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BU of 5v5l by Molmil
Crystal structure of HLA-B*5801 complex with HIV-1 gag derived peptide TW10
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-58 alpha chain, ...
著者Li, X, Wang, J.-H.
登録日2017-03-14
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Crystal structure of HLA-B*5801 with a TW10 HIV Gag epitope reveals a novel mode of peptide presentation.
Cell. Mol. Immunol., 14, 2017
1SYS
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BU of 1sys by Molmil
Crystal structure of HLA, B*4403, and peptide EEPTVIKKY
分子名称: Beta-2-microglobulin, Sorting nexin 5, leukocyte antigen (HLA) class I molecule
著者Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J.
登録日2004-04-01
公開日2004-10-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
J.Exp.Med., 200, 2004
1T21
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BU of 1t21 by Molmil
Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9, monoclinic crystal
分子名称: Beta-2-microglobulin, GAG PEPTIDE, HLA class I histocompatibility antigen, ...
著者Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y.
登録日2004-04-19
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.
J.Biol.Chem., 281, 2006
4I4W
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BU of 4i4w by Molmil
Peptide length determines the outcome of T cell receptor/peptide-MHCI engagement
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Wooldridge, L, Cole, D.K.
登録日2012-11-28
公開日2013-01-02
最終更新日2015-11-25
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Blood, 121, 2013
5VWF
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BU of 5vwf by Molmil
HLA-B*58:03 presenting LTVQVARVY
分子名称: Beta-2-microglobulin, MHC class I antigen, Nonamer peptide: LEU-THR-VAL-GLN-VAL-ALA-ARG-VAL-TYR
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-21
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
1TMC
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BU of 1tmc by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF A CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE MISSING THE ALPHA3 DOMAIN OF THE HEAVY CHAIN
分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-AW68), DECAMERIC PEPTIDE (EVAPPEYHRK)
著者Collins, E.J, Garboczi, D.N, Karpusas, M.N, Wiley, D.C.
登録日1994-12-19
公開日1995-03-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain.
Proc.Natl.Acad.Sci.USA, 92, 1995
5T6Z
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BU of 5t6z by Molmil
KIR3DL1 in complex with HLA-B*57:01-TW10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Decapeptide: THR-SER-THR-LEU-GLN-GLU-GLN-ILE-GLY-TRP, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2016-09-02
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Nat. Struct. Mol. Biol., 24, 2017
1TVB
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BU of 1tvb by Molmil
Crystal structure of Melanoma Antigen gp100(209-217) Bound to Human Class I MHC HLA-A2
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2004-06-29
公開日2005-04-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
4JQV
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BU of 4jqv by Molmil
HLA-B*18:01 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 173-180)
分子名称: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Theodossis, A, Welland, A, Gras, S, Rossjohn, J.
登録日2013-03-20
公開日2013-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献HLA Peptide Length Preferences Control CD8+ T Cell Responses.
J.Immunol., 191, 2013
1T1Y
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BU of 1t1y by Molmil
Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-5V
分子名称: Beta-2-microglobulin, GAG PEPTIDE, HLA class I histocompatibility antigen, ...
著者Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y.
登録日2004-04-19
公開日2005-09-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.
J.Biol.Chem., 281, 2006
1ONQ
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BU of 1onq by Molmil
Crystal Structure of CD1a in Complex with a Sulfatide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Zajonc, D.M, Elsliger, M.A, Teyton, L, Wilson, I.A.
登録日2003-02-28
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 A.
Nat.Immunol., 4, 2003
5VUE
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BU of 5vue by Molmil
HLA-B*57:01 presenting LTVQVARVW
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-19
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
5VWH
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BU of 5vwh by Molmil
HLA-B*58:01 presenting LSSPVTKSW
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-58 alpha chain, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-21
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.648 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
5VZ5
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Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G.
登録日2017-05-26
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5901 Å)
主引用文献A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Front Immunol, 9, 2018

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