PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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7CFS	Cryo-EM strucutre of human acid-sensing ion channel 1a at pH 8.0 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, CHOLESTEROL HEMISUCCINATE, ... 著者 Sun, D.M, Liu, S.L, Li, S.Y, Yang, F, Tian, C.L. 登録日 2020-06-28 公開日 2020-10-21 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1. Elife, 9, 2020
7CGY	Human DMC1 Q244M mutant of the post-synaptic complexes 分子名称: CALCIUM ION, Meiotic recombination protein DMC1/LIM15 homolog, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Chi, H.Y, Ho, M.C, Tsai, M.D, Luo, S.C, Yeh, H.Y. 登録日 2020-07-03 公開日 2020-11-18 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures. Nat Commun, 12, 2021
7C7N	Crystal structure of E.coli DNA gyrase B in complex with 6-fluoro-8-(methylamino)-2-oxo-1,2-dihydroquinoline derivative 分子名称: 4-[[6-fluoranyl-8-(methylamino)-2-oxidanylidene-1~{H}-quinolin-3-yl]carbonylamino]benzoic acid, DNA gyrase subunit B 著者 Mima, M, Ushiyama, F. 登録日 2020-05-26 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors. Bioorg.Med.Chem., 28, 2020
7CID	Crystal structure of P.aeruginosa LpxC in complex with inhibitor 分子名称: 1-[3-(4-chlorophenyl)propyl]imidazole, DIMETHYL SULFOXIDE, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... 著者 Baker, L.M, Mima, M, Surgenor, A, Robertson, A. 登録日 2020-07-07 公開日 2020-12-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020
7CM8	High resolution crystal structure of M92A mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae 分子名称: Cysteine synthase, GLYCEROL, SODIUM ION 著者 Kaushik, A, Rahisuddin, R, Saini, N, Kumaran, S. 登録日 2020-07-25 公開日 2020-08-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular mechanism of selective substrate engagement and inhibitor disengagement of cysteine synthase. J.Biol.Chem., 296, 2020
7C9X	Echovirus 3 F-particle 分子名称: MYRISTIC ACID, SPHINGOSINE, VP1, ... 著者 Wang, K, Rao, Z, Wang, X. 登録日 2020-06-08 公開日 2020-08-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage. Nat Commun, 11, 2020
7CPK	Xylanase R from Bacillus sp. TAR-1 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Endo-1,4-beta-xylanase A, ... 著者 Kuwata, K, Suzuki, M, Takita, T, Nakatani, K, Li, T, Katano, Y, Kojima, K, Mizutani, K, Mikami, B, Yatsunami, R, Nakamura, S, Yasukawa, K. 登録日 2020-08-07 公開日 2020-09-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Insight into the mechanism of thermostabilization of GH10 xylanase from Bacillus sp. strain TAR-1 by the mutation of S92 to E. Biosci.Biotechnol.Biochem., 85, 2021
7CRJ	Dark State Structure of Chloride ion pumping rhodopsin (ClR) with NTQ motif 分子名称: CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... 著者 Yun, J.H, Liu, H, Lee, W.T, Schmidt, M. 登録日 2020-08-13 公開日 2020-09-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser. Proc.Natl.Acad.Sci.USA, 118, 2021
7CJ3	Crystal structure of the transmembrane domain of Salpingoeca rosetta rhodopsin phosphodiesterase 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Phosphodiesterase, RETINAL 著者 Ikuta, T, Shihoya, W, Yamashita, K, Nureki, O. 登録日 2020-07-09 公開日 2020-11-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insights into the mechanism of rhodopsin phosphodiesterase. Nat Commun, 11, 2020
7CN7	T4 phage spackle protein gp61.3 complex with lysozyme domain of gp5 tail lysozyme 分子名称: 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Baseplate central spike complex protein gp5, ... 著者 Kanamaru, S, Leiman, P.G. 登録日 2020-07-30 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Structure and Function of the T4 Spackle Protein Gp61.3. Viruses, 12, 2020
7COF	Cholesterol esterase from Burkholderia stabilis (orthorhombic crystal form) 分子名称: Alpha/beta hydrolase, CALCIUM ION, GLYCEROL, ... 著者 Yasutake, Y, Tamura, T. 登録日 2020-08-04 公開日 2020-12-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.084 Å) 主引用文献 Bacterial triacylglycerol lipase is a potential cholesterol esterase: Identification of a key determinant for sterol-binding specificity. Int.J.Biol.Macromol., 167, 2021
7C2Q	The crystal structure of COVID-19 main protease in the apo state 分子名称: 3C-like proteinase 著者 Zhou, X.L, Zhong, F.L, Lin, C, Hu, X.H, Zhou, H, Wang, Q.S, Li, j, Zhang, J. 登録日 2020-05-08 公開日 2020-09-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure of SARS-CoV-2 main protease in the apo state. Sci China Life Sci, 64, 2021
7C33	Macro domain of SARS-CoV-2 in complex with ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 著者 Lin, M.H, Hsu, C.H. 登録日 2020-05-11 公開日 2020-11-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.83 Å) 主引用文献 Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain. Acs Infect Dis., 6, 2020
7C3L	Structure of L-lysine oxidase D212A/D315A in complex with L-tyrosine 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-lysine oxidase, ... 著者 Kitagawa, M, Matsumoto, Y, Inagaki, K, Imada, K. 登録日 2020-05-12 公開日 2020-09-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis of strict substrate recognition of l-lysine alpha-oxidase from Trichoderma viride. Protein Sci., 29, 2020
7CRC	Cryo-EM structure of plant NLR RPP1 tetramer in complex with ATR1 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Avirulence protein ATR1, ... 著者 Ma, S.C, Lapin, D, Liu, L, Sun, Y, Song, W, Zhang, X.X, Logemann, E, Yu, D.L, Wang, J, Jirschitzka, J, Han, Z.F, SchulzeLefert, P, Parker, J.E, Chai, J.J. 登録日 2020-08-13 公開日 2020-12-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme. Science, 370, 2020
7C7F	Crystal structures of AKR1C3 binary complex with NADP+ 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Aldo-keto reductase family 1 member C3, ... 著者 Irie, K, Toyooka, N, Endo, S. 登録日 2020-05-25 公開日 2020-09-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Development of Novel AKR1C3 Inhibitors as New Potential Treatment for Castration-Resistant Prostate Cancer. J.Med.Chem., 63, 2020
7C84	Esterase AlinE4 mutant, D162A 分子名称: ACETATE ION, CADMIUM ION, GLYCEROL, ... 著者 Li, Z, Li, J. 登録日 2020-05-28 公開日 2020-07-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.552 Å) 主引用文献 Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases. Biotechnol Biofuels, 13, 2020
7C7Z	Crystal structure of the flagellar junction protein FlgL from Legionella pneumophila 分子名称: Flagellar hook-associated protein 3 著者 Song, W.S, Hong, H.J, Yoon, S.I. 登録日 2020-05-27 公開日 2020-08-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Structural study of the flagellar junction protein FlgL from Legionella pneumophila. Biochem.Biophys.Res.Commun., 529, 2020
7CBI	Crystal structure of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica in complex with an inhibitor 分子名称: 1,2-ETHANEDIOL, 5-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)pentyl (2~{S},3~{R})-2-azanyl-3-oxidanyl-butanoate, GLYCEROL, ... 著者 Guo, J, Chen, B, Zhou, H. 登録日 2020-06-12 公開日 2020-10-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Structure-guided optimization and mechanistic study of a class of quinazolinone-threonine hybrids as antibacterial ThrRS inhibitors. Eur.J.Med.Chem., 207, 2020
7CQY	Tetrathionate hydrolase from Acidithiobacillus ferrooxidans mutant - D325N 分子名称: SULFATE ION, Tetrathionate hydrolase 著者 Tamada, T, Hirano, Y. 登録日 2020-08-12 公開日 2021-01-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.80035782 Å) 主引用文献 Reaction mechanism of tetrathionate hydrolysis based on the crystal structure of tetrathionate hydrolase from Acidithiobacillus ferrooxidans. Protein Sci., 30, 2020
7CCV	Crystal structure of death-associated protein kinase 1 in complex with piceatannol 分子名称: Death-associated protein kinase 1, PICEATANNOL, SULFATE ION 著者 Yokoyama, T, Suzuki, R, Mizuguchi, M. 登録日 2020-06-18 公開日 2021-01-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.753 Å) 主引用文献 Crystal structure of death-associated protein kinase 1 in complex with the dietary compound resveratrol. Iucrj, 8, 2020
7CSV	Pseudomonas aeruginosa antitoxin HigA 分子名称: HTH cro/C1-type domain-containing protein 著者 Song, Y.J, Luo, G.H, Bao, R. 登録日 2020-08-17 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs. Environ.Microbiol., 23, 2021
7CFL	X-ray structure of autolysin Acd24020 catalytic domain from Clostridium difficile 分子名称: CITRATE ANION, Putative cell wall hydrolase phosphatase-associated protein 著者 Kamitori, S, Tamai, E. 登録日 2020-06-26 公開日 2020-11-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Structural and biochemical characterizations of the novel autolysin Acd24020 from Clostridioides difficile and its full-function catalytic domain as a lytic enzyme. Mol.Microbiol., 115, 2021
7CTP	Crystal Structure of Human FAM129B/MINERVA/NIBAN2 分子名称: GLYCEROL, Protein Niban 2 著者 Hahn, H, Kim, H.S, Han, B.W. 登録日 2020-08-20 公開日 2020-11-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Insight on Functional Regulation of Human MINERVA Protein. Int J Mol Sci, 21, 2020
7CI4	Crystal structure of P.aeruginosa LpxC in complex with inhibitor 分子名称: (2R)-2-azanyl-4-methylsulfonyl-N-[3-(trifluoromethyloxy)phenyl]butanamide, CHLORIDE ION, MAGNESIUM ION, ... 著者 Mima, M, Baker, L.M, Surgenor, A, Robertson, A. 登録日 2020-07-07 公開日 2020-12-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Fragment-Based Discovery of Novel Non-Hydroxamate LpxC Inhibitors with Antibacterial Activity. J.Med.Chem., 63, 2020

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