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5UWQ
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Crystal Structure of CDC7 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Cell division cycle 7-related protein kinase, Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.278 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
1GAD
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BU of 1gad by Molmil
COMPARISON OF THE STRUCTURES OF WILD TYPE AND A N313T MUTANT OF ESCHERICHIA COLI GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASES: IMPLICATION FOR NAD BINDING AND COOPERATIVITY
分子名称: D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Duee, E, Olivier-Deyris, L, Fanchon, E, Corbier, C, Branlant, G, Dideberg, O.
登録日1995-10-24
公開日1996-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comparison of the structures of wild-type and a N313T mutant of Escherichia coli glyceraldehyde 3-phosphate dehydrogenases: implication for NAD binding and cooperativity.
J.Mol.Biol., 257, 1996
3BO1
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BU of 3bo1 by Molmil
Ribosome-SecY complex
分子名称: 23S RIBOSOMAL RNA, PREPROTEIN TRANSLOCASE SecE SUBUNIT, PREPROTEIN TRANSLOCASE SecY SUBUNIT, ...
著者Akey, C.W, Menetret, J.F.
登録日2007-12-15
公開日2008-12-09
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9.6 Å)
主引用文献Ribosome binding of a single copy of the SecY complex: implications for protein translocation
Mol.Cell, 28, 2007
5TLJ
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BU of 5tlj by Molmil
COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND M2191
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ...
著者Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
登録日2016-10-11
公開日2017-02-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography.
Mol. Immunol., 83, 2017
5T6R
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BU of 5t6r by Molmil
Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis: 60S-Nmd3 Complex
分子名称: 25S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ...
著者Malyutin, A.G, Musalgaonkar, S, Patchett, S, Frank, J, Johnson, A.W.
登録日2016-09-01
公開日2017-02-08
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis.
EMBO J., 36, 2017
3HSG
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BU of 3hsg by Molmil
Crystal structure of E. coli HPPK(Y53A) in complex with MgAMPCPP
分子名称: ACETATE ION, CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
著者Blaszczyk, J, Li, Y, Yan, H, Ji, X.
登録日2009-06-10
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK
To be Published
7EJO
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BU of 7ejo by Molmil
Structure of ERH-2 bound to TOST-1
分子名称: Enhancer of rudimentary homolog 2, Enhancer of rudimentary homolog 2,Protein tost-1
著者Wang, X, Xu, C.
登録日2021-04-02
公開日2021-08-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.191 Å)
主引用文献Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
5TFX
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BU of 5tfx by Molmil
New method for synthesis of benzoxazole amide inhibitors of carbonic anhydrase
分子名称: Carbonic anhydrase 2, GLYCEROL, N-(5-sulfamoyl-1,3-benzoxazol-2-yl)benzamide, ...
著者Peat, T.S, Supuran, C.
登録日2016-09-26
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Intramolecular oxidative deselenization of acylselenoureas: a facile synthesis of benzoxazole amides and carbonic anhydrase inhibitors.
Org. Biomol. Chem., 14, 2016
5UWT
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BU of 5uwt by Molmil
Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.342 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWS
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BU of 5uws by Molmil
Crystal Structure of X11L2 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Amyloid beta A4 precursor protein-binding family A member 3, Exportin-1,Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5DJR
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BU of 5djr by Molmil
Crystal structure of human FPPS in complex with biaryl compound 6
分子名称: 1H,1'H-4,4'-biindole-2-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5UQX
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BU of 5uqx by Molmil
USP7 in complex with GNE6776 (6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide)
分子名称: 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl[3,3'-bipyridine]-6-carboxamide, Ubiquitin carboxyl-terminal hydrolase 7
著者Murray, J.M, Rouge, L.
登録日2017-02-08
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献USP7 small-molecule inhibitors interfere with ubiquitin binding.
Nature, 550, 2017
1APY
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BU of 1apy by Molmil
HUMAN ASPARTYLGLUCOSAMINIDASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARTYLGLUCOSAMINIDASE, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Rouvinen, J, Oinonen, C.
登録日1995-06-14
公開日1996-12-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structure of human lysosomal aspartylglucosaminidase.
Nat.Struct.Biol., 2, 1995
1TMT
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BU of 1tmt by Molmil
CHANGES IN INTERACTIONS IN COMPLEXES OF HIRUDIN DERIVATIVES AND HUMAN ALPHA-THROMBIN DUE TO DIFFERENT CRYSTAL FORMS
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
著者Priestle, J.P, Gruetter, M.G.
登録日1994-05-26
公開日1994-09-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms.
Protein Sci., 2, 1993
6TIQ
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BU of 6tiq by Molmil
Refined solution NMR structure of hVDAC-1 in detergent micelles
分子名称: Voltage-dependent anion-selective channel protein 1
著者Boehm, R, Hiller, S, Wagner, G.
登録日2019-11-22
公開日2019-12-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Structural Basis for Low Conductance in the Membrane Protein VDAC upon beta-NADH Binding and Voltage Gating.
Structure, 28, 2020
3SR6
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BU of 3sr6 by Molmil
Crystal Structure of Reduced Bovine Xanthine Oxidase in Complex with Arsenite
分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ...
著者Cao, H, Hille, R.
登録日2011-07-07
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray Crystal Structure of Arsenite-Inhibited Xanthine Oxidase: Mu-Sulfido,Mu-Oxo Double Bridge between Molybdenum and Arsenic in the Active Site.
J.Am.Chem.Soc., 133, 2011
5VM9
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BU of 5vm9 by Molmil
Human Argonaute3 bound to guide RNA
分子名称: Protein argonaute-3, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3'), RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3')
著者Park, M.S, Nakanishi, K.
登録日2017-04-26
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Human Argonaute3 has slicer activity.
Nucleic Acids Res., 45, 2017
5B24
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BU of 5b24 by Molmil
The crystal structure of the nucleosome containing cyclobutane pyrimidine dimer
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Horikoshi, N, Tachiwana, H, Kagawa, W, Osakabe, A, Kurumizaka, H.
登録日2015-12-31
公開日2016-03-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Crystal structure of the nucleosome containing ultraviolet light-induced cyclobutane pyrimidine dimer
Biochem.Biophys.Res.Commun., 471, 2016
1KIX
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BU of 1kix by Molmil
Dimeric Structure of the O. nova Telomere End Binding Protein Alpha Subunit with Bound ssDNA
分子名称: 5'-D(*T*TP*TP*TP*GP*GP*GP*G)-3', SULFATE ION, Telomere-Binding Protein alpha Subunit
著者Peersen, O.B, Ruggles, J.A, Schultz, S.C.
登録日2001-12-03
公開日2002-02-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Dimeric structure of the Oxytricha nova telomere end-binding protein alpha-subunit bound to ssDNA.
Nat.Struct.Biol., 9, 2002
3AT1
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BU of 3at1 by Molmil
CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL PH
分子名称: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Gouaux, J.E, Lipscomb, W.N.
登録日1989-09-22
公開日1990-10-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
5UBD
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BU of 5ubd by Molmil
Crystal structure of the N-terminal domain (domain 1) of RctB, RctB-1-124-L48M
分子名称: RctB replication initiator protein
著者Orlova, N, Ivashkiv, O, Waldor, M.K, Jeruzalmi, D.
登録日2016-12-20
公開日2017-01-11
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献The replication initiator of the cholera pathogen's second chromosome shows structural similarity to plasmid initiators.
Nucleic Acids Res., 45, 2017
5DRM
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BU of 5drm by Molmil
Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a dichloro-substituted, 2,5-diarylthiophene-core ligand 4,4'-thiene-2,5-diylbis(3-chlorophenol)
分子名称: 4,4'-thiene-2,5-diylbis(3-chlorophenol), Estrogen receptor, Nuclear receptor coactivator 2
著者Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
登録日2015-09-16
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.241 Å)
主引用文献Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5UWP
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BU of 5uwp by Molmil
Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.054 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWO
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BU of 5uwo by Molmil
Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Engineered FMRP-1b peptide, Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.347 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWH
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BU of 5uwh by Molmil
Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017

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