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2GRH
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BU of 2grh by Molmil
M37V mutant of Scapharca dimeric hemoglobin, with CO bound
分子名称: CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE
著者Knapp, J.E, Pahl, R, Srajer, V, Royer Jr, W.E.
登録日2006-04-24
公開日2006-05-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Allosteric action in real time: Time-resolved crystallographic studies of a cooperative dimeric hemoglobin.
Proc.Natl.Acad.Sci.Usa, 103, 2006
226L
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BU of 226l by Molmil
GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W.
登録日1997-06-25
公開日1998-03-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions.
J.Mol.Biol., 277, 1998
6NX7
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BU of 6nx7 by Molmil
ECAII(D90T,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 5.6
分子名称: ACETIC ACID, CITRIC ACID, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-02-08
公開日2019-08-07
最終更新日2020-08-19
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
5CBY
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BU of 5cby by Molmil
AncGR2 DNA Binding Domain - (+)GRE Complex
分子名称: AncGR2 DNA Binding Domain, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3'), ...
著者Hudson, W.H, Ortlund, E.A.
登録日2015-07-01
公開日2015-12-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.
Proc.Natl.Acad.Sci.USA, 113, 2016
1TT2
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BU of 1tt2 by Molmil
Cryogenic crystal structure of Staphylococcal nuclease variant truncated Delta+PHS I92K
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Nguyen, D.M, Reynald, R.L, Gittis, A.G, Lattman, E.E.
登録日2004-06-21
公開日2004-07-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior
J.Mol.Biol., 341, 2004
1O0S
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BU of 1o0s by Molmil
Crystal Structure of Ascaris suum Malic Enzyme Complexed with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, NAD-dependent malic enzyme, TARTRONATE
著者Rao, G.S, Coleman, D.E, Karsten, W.E, Cook, P.F, Harris, B.G.
登録日2003-02-24
公開日2003-07-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic studies on Ascaris suum NAD-malic enzyme bound to reduced cofactor and identification of an effector site.
J.Biol.Chem., 278, 2003
2EXR
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BU of 2exr by Molmil
X-Ray Structure of Cytokinin Oxidase/Dehydrogenase (CKX) From Arabidopsis Thaliana AT5G21482
分子名称: Cytokinin dehydrogenase 7, FLAVIN-ADENINE DINUCLEOTIDE
著者Wesenberg, G.E, Phillips Jr, G.N, Han, B.W, Bitto, E, Bingman, C.A, Bae, E, Center for Eukaryotic Structural Genomics (CESG)
登録日2005-11-08
公開日2005-11-29
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.702 Å)
主引用文献Crystal structure of Arabidopsis thaliana cytokinin dehydrogenase.
Proteins, 70, 2008
1L5Q
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BU of 1l5q by Molmil
Human liver glycogen phosphorylase a complexed with caffeine, N-Acetyl-beta-D-glucopyranosylamine, and CP-403700
分子名称: CAFFEINE, Glycogen phosphorylase, liver form, ...
著者Ekstrom, J.L, Pauly, T.A, Carty, M.D, Soeller, W.C, Culp, J, Danley, D.E, Hoover, D.J, Treadway, J.L, Gibbs, E.M, Fletterick, R.J, Day, Y.S.N, Myszka, D.G, Rath, V.L.
登録日2002-03-07
公開日2002-12-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.
Chem.Biol., 9, 2002
3LOG
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BU of 3log by Molmil
Crystal structure of MbtI from Mycobacterium tuberculosis
分子名称: CARBONATE ION, GLYCEROL, Isochorismate synthase/isochorismate-pyruvate lyase mbtI, ...
著者Bulloch, E.M.M, Lott, J.S, Baker, E.N, Johnston, J.M.
登録日2010-02-03
公開日2011-02-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI).
Chemmedchem, 5, 2010
6NS3
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BU of 6ns3 by Molmil
Crystal structure of fungal lipoxygenase from Fusarium graminearum. I222 crystal form.
分子名称: FE (II) ION, lipoxygenase
著者Pakhomova, S, Boeglin, W.E, Neau, D.B, Bartlett, S.G, Brash, A.R, Newcomer, M.E.
登録日2019-01-24
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere.
Protein Sci., 28, 2019
223L
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BU of 223l by Molmil
GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS
分子名称: BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W.
登録日1997-06-25
公開日1998-03-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions.
J.Mol.Biol., 277, 1998
6NXB
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BU of 6nxb by Molmil
ECAII IN COMPLEX WITH CITRATE AT PH 7
分子名称: CITRIC ACID, GLYCEROL, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-02-08
公開日2019-08-07
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
6NYB
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BU of 6nyb by Molmil
Structure of a MAPK pathway complex
分子名称: 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, ADENOSINE-5'-DIPHOSPHATE, ...
著者Park, E, Rawson, S, Li, K, Jeon, H, Eck, M.J.
登録日2019-02-11
公開日2019-10-09
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.
Nature, 575, 2019
6NX6
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BU of 6nx6 by Molmil
ECAII(D90T,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 5
分子名称: ACETIC ACID, CITRIC ACID, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-02-08
公開日2019-08-07
最終更新日2020-08-19
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
3PL7
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BU of 3pl7 by Molmil
Crystal structure of Bcl-xL in complex with the BaxBH3 domain
分子名称: Apoptosis regulator BAX, Bcl-2-like protein 1
著者Czabotar, P.E, Colman, P.M.
登録日2010-11-14
公開日2010-12-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.613 Å)
主引用文献Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis
J.Biol.Chem., 286, 2011
6NXD
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BU of 6nxd by Molmil
TYPE I L-ASPARAGINASE FROM ESCHERICHIA COLI IN COMPLEX WITH CITRATE AT PH 4
分子名称: 1,2-ETHANEDIOL, ASPARAGINE, CHLORIDE ION, ...
著者Lubkowski, J, Wlodawer, A.
登録日2019-02-08
公開日2019-08-07
最終更新日2020-01-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Opportunistic complexes of E. coli L-asparaginases with citrate anions.
Sci Rep, 9, 2019
1ZYR
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BU of 1zyr by Molmil
Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ...
著者Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E.
登録日2005-06-10
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation.
Cell(Cambridge,Mass.), 122, 2005
5T0N
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BU of 5t0n by Molmil
Pseudo-apo structure of Sestrin2 at 3.0 angstrom resolution
分子名称: LEUCINE, Sestrin-2
著者Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U.
登録日2016-08-16
公開日2016-10-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献The apo-structure of the leucine sensor Sestrin2 is still elusive.
Sci.Signal., 9, 2016
6JX4
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BU of 6jx4 by Molmil
Crystal structure of EGFR 696-1022 T790M in complex with AZD9291 prepared by soaking
分子名称: Epidermal growth factor receptor, N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide
著者Zhu, S.J, Yan, X.E, Yun, C.H.
登録日2019-04-22
公開日2020-04-22
最終更新日2020-11-04
実験手法X-RAY DIFFRACTION (2.531 Å)
主引用文献Structural Basis of AZD9291 Selectivity for EGFR T790M.
J.Med.Chem., 63, 2020
2Q3W
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BU of 2q3w by Molmil
Ensemble refinement of the protein crystal structure of the cys84ala cys85ala double mutant of the [2Fe-2S] ferredoxin subunit of toluene-4-monooxygenase from Pseudomonas mendocina KR1
分子名称: 1,2-ETHANEDIOL, FE2/S2 (INORGANIC) CLUSTER, MAGNESIUM ION, ...
著者Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2007-05-30
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
1VTN
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BU of 1vtn by Molmil
CO-CRYSTAL STRUCTURE OF THE HNF-3/FORK HEAD DNA-RECOGNITION MOTIF RESEMBLES HISTONE H5
分子名称: DNA (5'-D(*GP*AP*CP*TP*AP*AP*GP*TP*CP*AP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*TP*GP*AP*CP*TP*TP*AP*GP*TP*C)-3'), HNF-3/FORK HEAD DNA-RECOGNITION MOTIF, ...
著者Clark, K.L, Halay, E.D, Lai, E, Burley, S.K.
登録日1995-01-06
公開日2011-07-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Co-Crystal Structure of the HNF-3/Fork Head DNA-Recognition Motif Resembles Histone H5
Nature, 364, 1993
3KFJ
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BU of 3kfj by Molmil
Crystal Structure of the Grb2 SH2 Domain in Complex with a Flexible Ac-pY-E-N-NH2 Tripeptide Mimic
分子名称: CHLORIDE ION, Growth factor receptor-bound protein 2, MAGNESIUM ION, ...
著者Clements, J.H.
登録日2009-10-27
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Thermodynamic and structural effects of conformational constraints in protein-ligand interactions. Entropic paradoxy associated with ligand preorganization.
J.Am.Chem.Soc., 131, 2009
2F58
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BU of 2f58 by Molmil
IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE)
分子名称: 1-IMINO-5-PENTANONE, PROTEIN (HIV-1 GP120), PROTEIN (IGG1 FAB 58.2 ANTIBODY (HEAVY CHAIN)), ...
著者Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A.
登録日1998-10-23
公開日1999-02-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
1W0Z
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BU of 1w0z by Molmil
Urokinase type plasminogen activator
分子名称: N-(BUTYLSULFONYL)-D-SERYL-N-{4-[AMINO(IMINO)METHYL]BENZYL}-L-ALANINAMIDE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR
著者Jacob, U.
登録日2004-06-15
公開日2008-05-20
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors.
J.Mol.Biol., 328, 2003
6JWL
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BU of 6jwl by Molmil
Crystal structure of EGFR 696-1022 L858R in complex with AZD9291
分子名称: Epidermal growth factor receptor, N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide
著者Yun, C.H, Zhu, S.J, Yan, X.E.
登録日2019-04-21
公開日2020-04-22
最終更新日2020-11-04
実験手法X-RAY DIFFRACTION (2.551 Å)
主引用文献Structural Basis of AZD9291 Selectivity for EGFR T790M.
J.Med.Chem., 63, 2020

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