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7THV
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BU of 7thv by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-12
公開日2022-02-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
7TIB
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BU of 7tib by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*AP*GP*AP*CP*AP*CP*TP*AP*CP*GP*AP*GP*TP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*AP*TP*GP*TP*AP*CP*TP*CP*GP*TP*AP*GP*TP*GP*TP*CP*T)-3'), ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-13
公開日2022-02-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
7TIC
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BU of 7tic by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-13
公開日2022-02-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
7TI8
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BU of 7ti8 by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA)
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-13
公開日2022-02-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
7TID
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BU of 7tid by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*AP*GP*AP*CP*AP*CP*TP*AP*CP*GP*AP*GP*TP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*AP*TP*GP*TP*AP*CP*TP*CP*GP*TP*AP*GP*TP*GP*TP*CP*T)-3'), ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-13
公開日2022-02-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
7TKU
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BU of 7tku by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA)
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-17
公開日2022-02-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
7WP3
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BU of 7wp3 by Molmil
Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution
分子名称: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, Proliferating cell nuclear antigen
著者Ahmad, M.I, Yadav, S.P, Singh, P.K, Sharma, P, Kaur, P, Sharma, S, Singh, T.P.
登録日2022-01-22
公開日2022-06-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.954 Å)
主引用文献Crystal structure of the complex of proliferating cell nuclear antigen (PCNA) from Leishmania donovani with 1,5-Bis (4-amidinophenoxy) pentane (PNT) at 2.95 A resolution
To Be Published
7U1A
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BU of 7u1a by Molmil
RFC:PCNA bound to dsDNA with a ssDNA gap of six nucleotides
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA - Primer, DNA - Template, ...
著者Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A.
登録日2022-02-20
公開日2022-07-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Elife, 11, 2022
7U19
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BU of 7u19 by Molmil
RFC:PCNA bound to nicked DNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA, MAGNESIUM ION, ...
著者Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A.
登録日2022-02-20
公開日2022-07-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Elife, 11, 2022
7U1P
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BU of 7u1p by Molmil
RFC:PCNA bound to DNA with a ssDNA gap of five nucleotides
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA - Primer, DNA - Template, ...
著者Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A.
登録日2022-02-21
公開日2022-07-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Elife, 11, 2022
8DR3
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BU of 8dr3 by Molmil
Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD
分子名称: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR7
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BU of 8dr7 by Molmil
Open state of RFC:PCNA bound to a nicked dsDNA
分子名称: DNA (26-MER), DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR4
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BU of 8dr4 by Molmil
Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) without NTD
分子名称: DNA (5'-D(P*AP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR5
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BU of 8dr5 by Molmil
Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD
分子名称: DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR1
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BU of 8dr1 by Molmil
Consensus closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2)
分子名称: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.14 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DQX
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BU of 8dqx by Molmil
Open state of RFC:PCNA bound to a 3' ss/dsDNA junction
分子名称: DNA (5'-D(*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*CP*CP*GP*AP*GP*CP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*GP*CP*CP*CP*GP*GP*A)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR0
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BU of 8dr0 by Molmil
Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction
分子名称: DNA (5'-D(P*CP*CP*CP*CP*GP*GP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*CP*GP*GP*GP*GP*GP*GP*GP*CP*CP*CP*CP*GP*GP*GP*G)-3'), GUANOSINE-5'-DIPHOSPHATE, ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DQZ
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BU of 8dqz by Molmil
Intermediate state of RFC:PCNA bound to a 3' ss/dsDNA junction
分子名称: DNA (5'-D(P*CP*CP*CP*CP*GP*GP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*CP*GP*GP*GP*GP*GP*GP*GP*CP*CP*CP*CP*GP*GP*GP*G)-3'), GUANOSINE-5'-DIPHOSPHATE, ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR6
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BU of 8dr6 by Molmil
Closed state of RFC:PCNA bound to a nicked dsDNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (32-MER), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8E84
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BU of 8e84 by Molmil
Human PCNA mutant- C148S
分子名称: Proliferating cell nuclear antigen
著者Magrino, J, Page, B, Gaubitz, C, Kelch, B.A.
登録日2022-08-25
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder.
J.Biol.Chem., 299, 2023
8B8T
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BU of 8b8t by Molmil
Open conformation of the complex of DNA ligase I on PCNA and DNA in the presence of ATP
分子名称: DNA ligase 1, Proliferating cell nuclear antigen
著者Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
登録日2022-10-05
公開日2023-01-11
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
8F5Q
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BU of 8f5q by Molmil
Crystal structure of human PCNA in complex with the PIP box of FBH1
分子名称: F-box DNA helicase 1, Proliferating cell nuclear antigen
著者Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T.
登録日2022-11-15
公開日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular insight into the PCNA-binding mode of FBH1.
Structure, 31, 2023
8COB
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BU of 8cob by Molmil
Crystal structure of human PCNA in complex with ERCC6L2 PIP box peptide
分子名称: DNA excision repair protein ERCC-6-like 2, Proliferating cell nuclear antigen
著者Ariza, A.
登録日2023-02-27
公開日2023-04-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献ERCC6L2 mitigates replication stress and promotes centromere stability.
Cell Rep, 42, 2023
8GCJ
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BU of 8gcj by Molmil
PCNA
分子名称: Proliferating cell nuclear antigen
著者Vandborg, B.C, Bruning, J.B.
登録日2023-03-01
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of apo pcna
To Be Published
8GJ5
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BU of 8gj5 by Molmil
fungal pcna and peptidomimetic
分子名称: Proliferating cell nuclear antigen, THR-ASP-ILE-ARG-ASN-PHE-PHE-HIS-SER
著者Vandborg, B, Bruning, J.B.
登録日2023-03-14
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus.
J Fungi, 9, 2023

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件を2024-06-12に公開中

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