7R41
 
 | | Bovine complex I in the presence of IM1761092, active class i (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7QV7
 | | Cryo-EM structure of Hydrogen-dependent CO2 reductase. | | 分子名称: | Hydrogen dependent carbon dioxide reductase subunit FdhF, Hydrogen dependent carbon dioxide reductase subunit HycB3, Hydrogen dependent carbon dioxide reductase subunit HycB4, ... | | 著者 | Dietrich, H.M, Righetto, R.D, Kumar, A, Wietrzynski, W, Schuller, S.K, Trischler, R, Wagner, J, Schwarz, F.M, Engel, B.D, Mueller, V, Schuller, J.M. | | 登録日 | 2022-01-19 | | 公開日 | 2022-07-06 | | 最終更新日 | 2022-08-10 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Membrane-anchored HDCR nanowires drive hydrogen-powered CO 2 fixation.
Nature, 607, 2022
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7QSO
 | | Bovine complex I in lipid nanodisc, State 3 (Slack) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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7QSN
 | | Bovine complex I in lipid nanodisc, Deactive-apo | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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7QSM
 | | Bovine complex I in lipid nanodisc, Deactive-ligand (composite) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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7QSL
 | | Bovine complex I in lipid nanodisc, Active-apo | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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7QSK
 | | Bovine complex I in lipid nanodisc, Active-Q10 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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7QSD
 | | Bovine complex I in the active state at 3.1 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7PSA
 | | The acetogenin-bound complex I of Mus musculus resolved to 3.4 angstroms | | 分子名称: | (3~{S},5~{S})-5-methyl-3-[(13~{R})-13-oxidanyl-13-[(2~{R},5~{R})-5-[(2~{R},5~{R})-5-[(1~{R})-1-oxidanylundecyl]oxolan-2-yl]oxolan-2-yl]tridecyl]oxolan-2-one, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | | 著者 | Grba, D, Hirst, J. | | 登録日 | 2021-09-22 | | 公開日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I.
J.Biol.Chem., 298, 2022
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7P7M
 | | Complex I from E. coli, DDM/LMNG-purified, inhibited by Piericidin A, Open state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P7L
 | | Complex I from E. coli, DDM/LMNG-purified, with NADH and FMN, Open state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P7K
 | | Complex I from E. coli, DDM/LMNG-purified, with DQ, Resting state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P7J
 | | Complex I from E. coli, DDM/LMNG-purified, with DQ, Open state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, CALCIUM ION, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P7E
 | | Complex I from E. coli, DDM/LMNG-purified, Apo, Resting state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P7C
 | | Complex I from E. coli, DDM/LMNG-purified, Apo, Open state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P69
 | | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Resting state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P64
 | | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Open state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P63
 | | Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Closed state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P62
 | | Complex I from E. coli, DDM-purified, Apo, Resting state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7P61
 | | Complex I from E. coli, DDM-purified, with NADH, Resting state | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | | 登録日 | 2021-07-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A universal coupling mechanism of respiratory complex I.
Nature, 609, 2022
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7O71
 | | Cryo-EM structure of a respiratory complex I | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | | 著者 | Parey, K, Vonck, J. | | 登録日 | 2021-04-12 | | 公開日 | 2021-11-10 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism.
Sci Adv, 7, 2021
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7O6Y
 | | Cryo-EM structure of respiratory complex I under turnover | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | 著者 | Parey, K, Vonck, J. | | 登録日 | 2021-04-12 | | 公開日 | 2021-11-10 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | High-resolution structure and dynamics of mitochondrial complex I-Insights into the proton pumping mechanism.
Sci Adv, 7, 2021
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7NZ1
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7NYV
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7NYU
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