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5W6X
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Crystal structure of the HsNUDT16 in complex with Mg+2 and ADP-ribose
分子名称: ACETIC ACID, ADENOSINE-5-DIPHOSPHORIBOSE, DI(HYDROXYETHYL)ETHER, ...
著者Thirawatananond, P, Gabelli, S.B.
登録日2017-06-18
公開日2018-12-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.
Sci Rep, 9, 2019
5VY2
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Crystal structure of the F36A mutant of HsNUDT16
分子名称: SODIUM ION, U8 snoRNA-decapping enzyme
著者Thirawatananond, P, Gabelli, S.B.
登録日2017-05-24
公開日2018-11-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.
Sci Rep, 9, 2019
3F6A
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Crystal structure of a hydrolase, NUDIX family from Clostridium perfringens
分子名称: Hydrolase, NUDIX family
著者Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-11-05
公開日2008-11-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structure of a hydrolase, NUDIX family from Clostridium perfringens
To be Published
2AZW
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Crystal structure of the MutT/nudix family protein from Enterococcus faecalis
分子名称: MutT/nudix family protein, PENTAETHYLENE GLYCOL
著者Zhang, R, Zhou, M, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2005-09-12
公開日2006-01-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The 1.9A crystal structure of the MutT/nudix family protein from Enterococcus faecalis
To be Published
1I9A
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STRUCTURAL STUDIES OF CHOLESTEROL BIOSYNTHESIS: MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE AND ISOPENTENYL DIPHOSPHATE ISOMERASE
分子名称: ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE, MANGANESE (II) ION
著者Bonanno, J.B, Edo, C, Eswar, N, Pieper, U, Romanowski, M.J, Ilyin, V, Gerchman, S.E, Kycia, H, Studier, F.W, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2001-03-18
公開日2001-03-28
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural genomics of enzymes involved in sterol/isoprenoid biosynthesis.
Proc.Natl.Acad.Sci.USA, 98, 2001
2B2K
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structure of Y104F IDI-1 mutant in complex with EIPP
分子名称: 4-HYDROXY-3-METHYL BUTYL DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, MAGNESIUM ION, ...
著者Wouters, J.
登録日2005-09-19
公開日2006-09-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural role for Tyr-104 in Escherichia coli isopentenyl-diphosphate isomerase: site-directed mutagenesis, enzymology, and protein crystallography
J.Biol.Chem., 281, 2006
5ANV
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MTH1 in complex with compound 15
分子名称: 4-(4-CHLORO-2-FLUORO-ANILINO)-6,7-DIMETHOXY-N-METHYL-QUINOLINE-3-CARBOXAMIDE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE
著者Read, J.A, Breed, J.
登録日2015-09-08
公開日2016-03-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Potent and Selective Inhibitors of Mth1 Probe its Role in Cancer Cell Survival.
J.Med.Chem., 59, 2016
5ANU
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MTH1 in complex with compound 15
分子名称: 13-(METHYLAMINO)-23,24,25-TRIOXA-17,18,19,21-TETRAZATETRACYCLO-TRICOSA-1(3),2(10),4(11),12(14),13(18),16(19)-HEXAN-15-ONE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, DIMETHYL SULFOXIDE
著者Read, J.A, Breed, J.
登録日2015-09-08
公開日2016-03-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Potent and Selective Inhibitors of Mth1 Probe its Role in Cancer Cell Survival.
J.Med.Chem., 59, 2016
1JKN
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Solution Structure of the Nudix Enzyme Diadenosine Tetraphosphate Hydrolase from Lupinus angustifolius Complexed with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase
著者Fletcher, J.I, Swarbrick, J.D, Maksel, D, Gayler, K.R, Gooley, P.R.
登録日2001-07-12
公開日2002-02-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of Ap(4)A hydrolase complexed with ATP-MgF(x) reveals the basis of substrate binding.
Structure, 10, 2002
5WJI
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Crystal structure of the F61S mutant of HsNUDT16
分子名称: ACETIC ACID, CHLORIDE ION, SULFATE ION, ...
著者Thirawatananond, P, Gabelli, S.B.
登録日2017-07-23
公開日2018-10-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.
Sci Rep, 9, 2019
1K2E
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BU of 1k2e by Molmil
crystal structure of a nudix protein from Pyrobaculum aerophilum
分子名称: ACETIC ACID, GLYCEROL, NICKEL (II) ION, ...
著者Wang, S, Mura, C, Sawaya, M.R, Cascio, D, Eisenberg, D.
登録日2001-09-26
公開日2002-04-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets.
Acta Crystallogr.,Sect.D, 58, 2002
2B06
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Crystal structure of the MutT/nudix family protein from Streptococcus pneumoniae
分子名称: MAGNESIUM ION, MutT/nudix family protein
著者Zhang, R, Zhou, M, Abdullah, J, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2005-09-13
公開日2006-01-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The 1.4 A crystal structure of the MutT/nudix family protein from Streptococcus pneumoniae
To be Published
2B0V
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NUDIX hydrolase from Nitrosomonas europaea.
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, NUDIX hydrolase, ...
著者Osipiuk, J, Skarina, T, Savchenko, A, Edwards, A, Joachimiak, A, MCSG, Midwest Center for Structural Genomics (MCSG)
登録日2005-09-14
公開日2005-09-27
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献X-ray structure of NUDIX hydrolase from Nitrosomonas europaea.
To be Published
5CFI
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BU of 5cfi by Molmil
Structural and functional attributes of malaria parasite Ap4A hydrolase
分子名称: BIS(5'-nucleosyl)-tetraphosphatase (Diadenosine tetraphosphatase), putative
著者Sharma, A, Yogavel, M, Sharma, A.
登録日2015-07-08
公開日2016-02-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and functional attributes of malaria parasite diadenosine tetraphosphate hydrolase
Sci Rep, 6, 2016
5C8L
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Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, NudF protein, ...
著者Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M.
登録日2015-06-25
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus.
Plos One, 10, 2015
5WS7
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Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 2-oxo-dATP
分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
著者Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y.
登録日2016-12-05
公開日2017-01-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity
J. Biol. Chem., 292, 2017
5WWD
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BU of 5wwd by Molmil
Crystal structure of AtNUDX1
分子名称: AMMONIUM ION, GLYCEROL, MAGNESIUM ION, ...
著者Liu, J, Guan, Z, Yan, L, Zou, T, Yin, P.
登録日2016-12-31
公開日2017-11-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.386 Å)
主引用文献Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis.
Mol Plant, 11, 2018
5WY6
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Crystal structure of AtNUDX1 (E56A)
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Nudix hydrolase 1, ...
著者Liu, J, Guan, Z, Yan, L, Zou, T, Yin, P.
登録日2017-01-11
公開日2017-11-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.779 Å)
主引用文献Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis.
Mol Plant, 11, 2018
2DUK
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BU of 2duk by Molmil
Crystal structure of MS0616
分子名称: MS0616
著者Hosaka, T, Nishino, A, Uchikubo, K.-T, Kishishita, S, Murayama, K, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-07-24
公開日2007-01-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Crystal structure of MS0616
To be Published
2DSC
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Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and ADP-ribose
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADP-sugar pyrophosphatase, MAGNESIUM ION
著者Zha, M, Zhong, C, Ding, J.
登録日2006-06-28
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006
1IRY
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Solution structure of the hMTH1, a nucleotide pool sanitization enzyme
分子名称: hMTH1
著者Mishima, M, Itoh, N, Sakai, Y, Kamiya, H, Nakabeppu, Y, Shirakawa, M.
登録日2001-10-25
公開日2003-12-23
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates
J.Biol.Chem., 279, 2004
1KTG
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Crystal Structure of a C. elegans Ap4A Hydrolase Binary Complex
分子名称: ADENOSINE MONOPHOSPHATE, Diadenosine Tetraphosphate Hydrolase, HYDROXIDE ION, ...
著者Bailey, S, Sedelnikova, S.E, Blackburn, G.M, Abdelghany, H.M, Baker, P.J, McLennan, A.G, Rafferty, J.B.
登録日2002-01-16
公開日2002-05-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms
Structure, 10, 2002
2DSD
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Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and AMP
分子名称: ADENOSINE MONOPHOSPHATE, ADP-sugar pyrophosphatase, MAGNESIUM ION
著者Zha, M, Zhong, C, Ding, J.
登録日2006-06-28
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006
2FKB
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Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12
分子名称: ACETATE ION, GLYCEROL, MAGNESIUM ION, ...
著者Nocek, B, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-01-04
公開日2006-02-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12
To be Published
3GG6
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Crystal structure of the NUDIX domain of human NUDT18
分子名称: Nucleoside diphosphate-linked moiety X motif 18
著者Tresaugues, L, Siponen, M.I, Lehtio, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2009-02-27
公開日2009-03-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the NUDIX domain of human NUDT18
To be Published

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