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5L7A
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The crystal structure of the Human SNF5/INI1 domain
分子名称: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
著者Allen, M.D, Zinzalla, G, Bycroft, M.
登録日2016-06-02
公開日2017-05-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献The structure of INI1/hSNF5 RPT1 and its interactions with the c-MYC:MAX heterodimer provide insights into the interplay between MYC and the SWI/SNF chromatin remodeling complex.
FEBS J., 285, 2018
5L7B
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Solution structure of the human SNF5/INI1 domain
分子名称: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
著者Allen, M.D, Zinzalla, G, Bycroft, M.
登録日2016-06-02
公開日2017-05-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The structure of INI1/hSNF5 RPT1 and its interactions with the c-MYC:MAX heterodimer provide insights into the interplay between MYC and the SWI/SNF chromatin remodeling complex.
FEBS J., 285, 2018
1SBE
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SOYBEAN AGGLUTININ FROM GLYCINE MAX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MANGANESE (II) ION, ...
著者Dessen, A, Olsen, L.R, Gupta, D, Sabesan, S, Sacchettini, J.C, Brewer, C.F.
登録日1995-07-13
公開日1998-04-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献X-ray crystallographic studies of unique cross-linked lattices between four isomeric biantennary oligosaccharides and soybean agglutinin.
Biochemistry, 36, 1997
7AYS
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BU of 7ays by Molmil
Structure of bovine trypsin determined from single femtosecond snapshots per orientation at room temperature
分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
著者Jensen, M.
登録日2020-11-13
公開日2021-01-20
最終更新日2021-08-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High-resolution macromolecular crystallography at the FemtoMAX beamline with time-over-threshold photon detection.
J.Synchrotron Radiat., 28, 2021
8C8A
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The NMR structure of the MAX28 effector from Magnaporthe oryzae
分子名称: But2 domain-containing protein
著者Lahfa, M, Padilla, A, de Guillen, K, Kroj, T, Roumestand, C, Barthe, P.
登録日2023-01-19
公開日2024-02-14
実験手法SOLUTION NMR
主引用文献1H, 15N Backbone and side-chain NMR assignments for a MAX effector from Magnaporthe oryzae
To Be Published
2KYQ
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1H, 15N, 13C chemical shifts and structure of CKR-brazzein
分子名称: Defensin-like protein
著者Dittli, S.M, Assadi-Porter, F.M, Rao, H, Tonelli, M.
登録日2010-06-07
公開日2011-05-18
最終更新日2011-11-30
実験手法SOLUTION NMR
主引用文献Structural role of the terminal disulfide bond in the sweetness of brazzein.
Chem Senses, 36, 2011
2L07
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1H, 13C, and 15N chemical shifts and structure of brazzein-derived peptide CKR-PNG
分子名称: Defensin-like protein
著者Dittli, S.M, Assadi-Porter, F.M, Rao, H, Tonelli, M.
登録日2010-06-30
公開日2011-06-22
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural role of the terminal disulfide bond in the sweetness of brazzein.
Chem Senses, 36, 2011
3PF4
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Crystal structure of Bs-CspB in complex with r(GUCUUUA)
分子名称: Cold shock protein cspB, MAGNESIUM ION, SODIUM ION, ...
著者Sachs, R, Max, K.E.A, Heinemann, U.
登録日2010-10-27
公開日2011-09-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution.
Rna, 18, 2012
3PF5
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Crystal structure of Bs-CspB in complex with rU6
分子名称: Cold shock protein cspB, MAGNESIUM ION, hexaribouracil (rU6)
著者Sachs, R, Max, K.E.A, Heinemann, U.
登録日2010-10-27
公開日2011-09-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution.
Rna, 18, 2012
7CKA
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The structure of Glycine max (Soybean) Heme oxygenase 1
分子名称: CITRIC ACID, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
著者Tohda, R, Tanaka, H, Kurisu, G.
登録日2020-07-16
公開日2020-12-30
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Crystal structure of higher plant heme oxygenase-1 and its mechanism of interaction with ferredoxin.
J.Biol.Chem., 296, 2020
2Y3P
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Crystal structure of N-terminal domain of GyrA with the antibiotic simocyclinone D8
分子名称: DNA GYRASE SUBUNIT A, MAGNESIUM ION, SIMOCYCLINONE D8
著者Edwards, M.J, Flatman, R.H, Mitchenall, L.A, Stevenson, C.E.M, Le, T.B.K, Clarke, T.A, McKay, A.R, Fiedler, H.-P, Buttner, M.J, Lawson, D.M, Maxwell, A.
登録日2010-12-22
公開日2010-12-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase.
Science, 326, 2009
2Y31
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Simocyclinone C4 bound form of TetR-like repressor SimR
分子名称: CALCIUM ION, CHLORIDE ION, PENTAETHYLENE GLYCOL, ...
著者Le, T.B.K, Stevenson, C.E.M, Fiedler, H.-P, Maxwell, A, Lawson, D.M, Buttner, M.J.
登録日2010-12-17
公開日2011-03-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of the Tetr-Like Simocyclinone Efflux Pump Repressor, Simr, and the Mechanism of Ligand-Mediated Derepression.
J.Mol.Biol., 408, 2011
2Y30
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Simocyclinone D8 bound form of TetR-like repressor SimR
分子名称: CHLORIDE ION, PUTATIVE REPRESSOR SIMREG2, SIMOCYCLINONE D8
著者Le, T.B.K, Stevenson, C.E.M, Fiedler, H.-P, Maxwell, A, Lawson, D.M, Buttner, M.J.
登録日2010-12-17
公開日2011-03-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of the Tetr-Like Simocyclinone Efflux Pump Repressor, Simr, and the Mechanism of Ligand-Mediated Derepression.
J.Mol.Biol., 408, 2011
5HZG
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BU of 5hzg by Molmil
The crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex
分子名称: (2Z)-2-methylbut-2-ene-1,4-diol, F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A, ...
著者Yao, R.F, Ming, Z.H, Yan, L.M, Rao, Z.H, Lou, Z.Y, Xie, D.X.
登録日2016-02-02
公開日2016-08-03
最終更新日2016-08-31
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献DWARF14 is a non-canonical hormone receptor for strigolactone
Nature, 536, 2016
7M7W
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BU of 7m7w by Molmil
Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal antibody S2H97 Fab heavy chain, Monoclonal antibody S2H97 Fab light chain, ...
著者Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M.
登録日2021-03-29
公開日2021-05-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
6Z1A
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Ternary complex of Staphylococcus aureus DNA gyrase with AMK12 and DNA
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Kolaric, A, Germe, T, Hrast, M, Stevenson, C.E.M, Lawson, D.M, Burton, N, Voros, J, Maxwell, A, Minovski, N, Anderluh, M.
登録日2020-05-13
公開日2020-11-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bonds.
Nat Commun, 12, 2021
7P2W
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E.coli GyrB24 with inhibitor LMD92 (EBL2682)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[[3,4-bis(chloranyl)-5-methyl-1H-pyrrol-2-yl]carbonylamino]-4-[(3-carboxyphenyl)methoxy]-1,3-benzothiazole-6-carboxylic acid, DNA gyrase subunit B, ...
著者Stevenson, C.E.M, Lawson, D.M, Maxwell, A.M, Henderson, S.R, Kikelj, D, Durcik, M, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P.
登録日2021-07-06
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa.
J.Med.Chem., 66, 2023
7P2M
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E.coli GyrB24 with inhibitor LMD43 (EBL2560)
分子名称: 2-[[3,4-bis(chloranyl)-5-methyl-1~{H}-pyrrol-2-yl]carbonylamino]-4-phenylmethoxy-1,3-benzothiazole-6-carboxylic acid, DNA gyrase subunit B, PHOSPHATE ION
著者Stevenson, C.E.M, Lawson, D.M, Maxwell, A.M, Henderson, S.R, Kikelj, D, Durcik, M, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P.
登録日2021-07-06
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa.
J.Med.Chem., 66, 2023
7P2N
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E.coli GyrB24 with inhibitor LSJ38 (EBL2684)
分子名称: 2-[[3,4-bis(chloranyl)-5-methyl-1H-pyrrol-2-yl]carbonylamino]-5-oxidanyl-1,3-benzothiazole-6-carboxylic acid, DNA gyrase subunit B, PHOSPHATE ION
著者Stevenson, C.E.M, Lawson, D.M, Maxwell, A.M, Henderson, S.R, Kikelj, D, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P.
登録日2021-07-06
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens.
Acs Omega, 8, 2023
8BN6
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Pseudomonas aeruginosa DNA gyrase B 24kDa ATPase subdomain complexed with EBL3021
分子名称: 2-[[3,4-bis(chloranyl)-5-methyl-1~{H}-pyrrol-2-yl]carbonylamino]-4-morpholin-4-yl-1,3-benzothiazole-6-carboxylic acid, CALCIUM ION, DNA gyrase subunit B
著者Durcik, M, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P, Mundy, J.E.A, Stevenson, C.E.M, Burton, N, Lawson, D.M, Maxwell, A, Kikelj, D.
登録日2022-11-12
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus .
J.Med.Chem., 66, 2023
6ZT5
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Complex between a homodimer of Mycobacterium smegmatis MfpA and a single copy of the N-terminal 47 kDa fragment of the Mycobacterium smegmatis DNA Gyrase B subunit
分子名称: DNA gyrase subunit B, Pentapeptide repeat protein MfpA, SULFATE ION
著者Feng, L, Mundy, J.E.A, Stevenson, C.E.M, Mitchenall, L.A, Lawson, D.M, Mi, K, Maxwell, A.
登録日2020-07-17
公開日2021-03-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic.
Proc.Natl.Acad.Sci.USA, 118, 2021
6ZT3
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N-terminal 47 kDa fragment of the Mycobacterium smegmatis DNA Gyrase B subunit complexed with ADPNP
分子名称: 1,2-ETHANEDIOL, DNA gyrase subunit B, MAGNESIUM ION, ...
著者Feng, L, Mundy, J.E.A, Stevenson, C.E.M, Mitchenall, L.A, Lawson, D.M, Mi, K, Maxwell, A.
登録日2020-07-17
公開日2021-03-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic.
Proc.Natl.Acad.Sci.USA, 118, 2021
6ZT4
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Pentapeptide repeat protein MfpA from Mycobacterium smegmatis
分子名称: 1,2-ETHANEDIOL, Pentapeptide repeat protein MfpA
著者Feng, L, Mundy, J.E.A, Stevenson, C.E.M, Mitchenall, L.A, Lawson, D.M, Mi, K, Maxwell, A.
登録日2020-07-17
公開日2021-03-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic.
Proc.Natl.Acad.Sci.USA, 118, 2021
7P2X
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E.coli GyrB24 with inhibitor KOB20 (EBL2583)
分子名称: (2Z)-2-[[4,5-bis(bromanyl)-1H-pyrrol-2-yl]carbonylimino]-3-(phenylmethyl)-1,3-benzothiazole-6-carboxylic acid, DNA gyrase subunit B, PHOSPHATE ION
著者Stevenson, C.E.M, Lawson, D.M, Maxwell, A.M, Henderson, S.R, Kikelj, D, Benek, O, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P.
登録日2021-07-06
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献E.coli GyrB24 with inhibitor KOB20 (EBL2583)
TO BE PUBLISHED
7PTF
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Pseudomonas aeruginosa DNA gyrase B 24kDa ATPase subdomain complexed with novobiocin
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA gyrase subunit B, ...
著者Cotman, A.E, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P, Mundy, J.E.A, Stevenson, C.E.M, Burton, N, Lawson, D.M, Maxwell, A, Kikelj, D.
登録日2021-09-27
公開日2022-10-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa.
J.Med.Chem., 66, 2023

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