PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

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6POQ	Crystal Structure of EcDsbA in complex with anisidine 16 分子名称: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, {6-[(4-methoxyphenyl)amino]-1-benzofuran-3-yl}acetic acid 著者 Ilyichova, O.V, Scanlon, M.J. 登録日 2019-07-04 公開日 2019-11-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors. Molecules, 24, 2019
6PQK	Cryogenic crystal structure of barnase A43C/S80C bound to barstar C40A/S59C/A67C/C82A 分子名称: 1,2-ETHANEDIOL, Barstar, PHOSPHATE ION, ... 著者 Caro, J.A, Djanto, V, Wand, A.J. 登録日 2019-07-09 公開日 2020-07-15 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Targeting conformational entropy to modulate binding affinity To Be Published
6POR	Antimicrobial lasso peptide ubonodin 分子名称: Ubonodin 著者 Link, A.J, Cheung-Lee, W.L. 登録日 2019-07-05 公開日 2019-12-04 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex. Chembiochem, 21, 2020
6PX0	Crystal structure of the TPR domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) 分子名称: 1,2-ETHANEDIOL, Aryl-hydrocarbon-interacting protein-like 1, BETA-MERCAPTOETHANOL, ... 著者 Yadav, R.P, Artemyev, N.O. 登録日 2019-07-24 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Interaction of the tetratricopeptide repeat domain of aryl hydrocarbon receptor-interacting protein-like 1 with the regulatory P gamma subunit of phosphodiesterase 6. J.Biol.Chem., 294, 2019
6PV1	Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: Aib in the metal-binding turn 分子名称: Transcription factor Sp1, ZINC ION 著者 Rao, S.R, Horne, W.S. 登録日 2019-07-19 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns. Pept Sci (Hoboken), 112, 2020
6PV3	Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: altered helix, loop, turn, and sheet 分子名称: Transcription factor Sp1, ZINC ION 著者 Rao, S.R, Horne, W.S. 登録日 2019-07-19 公開日 2020-06-24 最終更新日 2024-07-10 実験手法 SOLUTION NMR 主引用文献 Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns. Pept Sci (Hoboken), 112, 2020
6PWU	Structure of full-length, fully glycosylated, non-modified HIV-1 gp160 bound to PG16 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pan, J, Chen, B, Harrison, S.C. 登録日 2019-07-23 公開日 2020-02-26 最終更新日 2022-03-16 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Cryo-EM Structure of Full-length HIV-1 Env Bound With the Fab of Antibody PG16. J.Mol.Biol., 432, 2020
6PVZ	E.coli DsbA in complex with benzofuran compound 28 ((6-benzyl-1-benzofuran-3-yl)acetic acid) 分子名称: (6-benzyl-1-benzofuran-3-yl)acetic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA 著者 Wang, G, Heras, B. 登録日 2019-07-21 公開日 2019-12-25 最終更新日 2020-10-07 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors. Molecules, 24, 2019
6PVY	E.coli DsbA in complex with benzofuran compound 26 ([6-(3-methoxyphenoxy)-1-benzofuran-3-yl]acetic acid) 分子名称: COPPER (II) ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Wang, G, Heras, B. 登録日 2019-07-21 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors. Molecules, 24, 2019
6Q1U	Structure of plasmin and peptide complex 分子名称: 1-methyl-1H-1,2,3-triazole, GLY-ARG-ALA-TYR-LYS-SER-LYS-PRO-PRO-ILE-ALA-PHE-PRO-ASP, Plasminogen 著者 Wu, G, Law, R.H.P. 登録日 2019-08-06 公開日 2020-04-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3467 Å) 主引用文献 Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides. Angew.Chem.Int.Ed.Engl., 59, 2020
6QB2	Crystal structure of the cystatin-based engineered protein scaffold SQT-1C 分子名称: Monomer of SQT-1C 著者 Levy, C.W. 登録日 2018-12-20 公開日 2019-07-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Studies of the oligomerisation mechanism of a cystatin-based engineered protein scaffold. Sci Rep, 9, 2019
6QH3	Catalytic domain of the human ubiquitin-conjugating enzyme UBE2S C118M 分子名称: 1,2-ETHANEDIOL, Ubiquitin-conjugating enzyme E2 S 著者 Liess, A.K.L, Lorenz, S. 登録日 2019-01-15 公開日 2019-07-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination. Structure, 27, 2019
6QHK	PAO-linked dimer of the catalytic domain of the human ubiquitin-conjugating enzyme UBE2S 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Phenylarsine oxide, ... 著者 Liess, A.K.L, Lorenz, S. 登録日 2019-01-16 公開日 2019-07-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination. Structure, 27, 2019
6PV2	Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: Orn in the metal-binding turn 分子名称: Transcription factor Sp1, ZINC ION 著者 Rao, S.R, Horne, W.S. 登録日 2019-07-19 公開日 2020-06-24 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns. Pept Sci (Hoboken), 112, 2020
6QRJ	Crystal structure of ShkA full-length in complex with AMPPNP 分子名称: Hybrid kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Dubey, B.N, Schirmer, T. 登録日 2019-02-19 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation. Proc.Natl.Acad.Sci.USA, 117, 2020
6QUU	Crystal Structure of KRAS-G12D in complex with GMP-PCP 分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER 著者 Fischer, G, Kessler, D, Muellauer, B, Wolkerstorfer, B. 登録日 2019-02-28 公開日 2019-07-31 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.477 Å) 主引用文献 KRAS Binders Hidden in Nature. Chemistry, 25, 2019
6QVJ	HsCKK (human CAMSAP1) decorated 14pf taxol-GDP microtubule 分子名称: Calmodulin-regulated spectrin-associated protein 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Atherton, J.M, Luo, Y, Xiang, S, Yang, C, Jiang, K, Stangier, M, Vemu, A, Cook, A, Wang, S, Roll-Mecak, A, Steinmetz, M.O, Akhmanova, A, Baldus, M, Moores, C.A. 登録日 2019-03-02 公開日 2019-11-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural determinants of microtubule minus end preference in CAMSAP CKK domains. Nat Commun, 10, 2019
6QUV	Crystal Structure of KRAS-G12D in complex with GMP-PCP and compound 15R 分子名称: (6~{a}~{R},11~{b}~{S})-6~{a}-(1,4-dimethylpiperidin-4-yl)-7,11~{b}-dihydro-6~{H}-indolo[2,3-c]isoquinolin-5-one, GTPase KRas, MAGNESIUM ION, ... 著者 Fischer, G, Kessler, D, Muellauer, B, Wolkerstorfer, B. 登録日 2019-02-28 公開日 2019-07-31 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.475 Å) 主引用文献 KRAS Binders Hidden in Nature. Chemistry, 25, 2019
6QUX	Crystal Structure of KRAS-G12D in Complex with Natural Product-Like Compound 15 分子名称: (6~{a}~{R},11~{b}~{S})-6~{a}-(1,4-dimethylpiperidin-4-yl)-7,11~{b}-dihydro-6~{H}-indolo[2,3-c]isoquinolin-5-one, 1,2-ETHANEDIOL, GTPase KRas, ... 著者 Fischer, G, Kessler, D, Muellauer, B, Wolkerstorfer, B. 登録日 2019-02-28 公開日 2019-07-31 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 KRAS Binders Hidden in Nature. Chemistry, 25, 2019
6QZG	Beta-glucose 1,6-bisphosphonate bound to wild type beta-phosphoglucomutse in an open conformation. 分子名称: 3,7-anhydro-1,2,8-trideoxy-1,8-diphosphono-D-glycero-D-gulo-octitol, Beta-phosphoglucomutase, MAGNESIUM ION 著者 Robertson, A.J. 登録日 2019-03-11 公開日 2020-04-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Beta-glucose 1,6-bisphosphonate bound to wild type beta-phosphoglucomutse in an open conformation. To Be Published
6QRL	Crystal structure of ShkA _Rec1 in complex with c-di-GMP 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Hybrid kinase, SULFATE ION 著者 Dubey, B.N, Schirmer, T. 登録日 2019-02-19 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation. Proc.Natl.Acad.Sci.USA, 117, 2020
6QVE	NgCKK (Naegleria Gruberi CKK) decorated 14pf taxol-GDP microtubule 分子名称: Beta1-tubulin, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Atherton, J.M, Luo, Y, Xiang, S, Yang, C, Jiang, K, Stangier, M, Vemu, A, Cook, A, Wang, S, Roll-Mecak, A, Steinmetz, M.O, Akhmanova, A, Baldus, M, Moores, C.A. 登録日 2019-03-01 公開日 2019-11-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural determinants of microtubule minus end preference in CAMSAP CKK domains. Nat Commun, 10, 2019
6QUY	NgCKK (N.Gruberi CKK) decorated 13pf taxol-GDP microtubule 分子名称: CKK domain protein, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Atherton, J.M, Luo, Y, Xiang, S, Yang, C, Jiang, K, Stangier, M, Vemu, A, Cook, A, Wang, S, Roll-Mecak, A, Steinmetz, M.O, Akhmanova, A, Baldus, M, Moores, C.A. 登録日 2019-02-28 公開日 2019-11-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural determinants of microtubule minus end preference in CAMSAP CKK domains. Nat Commun, 10, 2019
6QUW	Crystal Structure of KRAS-G12D in Complex with Natural Product-Like Compound 9b 分子名称: (3~{a}~{R},8~{b}~{S})-2,2,3~{a},8~{b}-tetramethyl-3,4-dihydro-1~{H}-pyrrolo[2,3-b]indole, GTPase KRas, MAGNESIUM ION, ... 著者 Fischer, G, Kessler, D, Muellauer, B, Wolkerstorfer, B. 登録日 2019-02-28 公開日 2019-07-31 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.242 Å) 主引用文献 KRAS Binders Hidden in Nature. Chemistry, 25, 2019
6QUS	HsCKK (human CAMSAP1) decorated 13pf taxol-GDP microtubule 分子名称: Calmodulin-regulated spectrin-associated protein 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Atherton, J.M, Luo, Y, Xiang, S, Yang, C, Jiang, K, Stangier, M, Vemu, A, Cook, A, Wang, S, Roll-Mecak, A, Steinmetz, M.O, Akhmanova, A, Baldus, M, Moores, C.A. 登録日 2019-02-28 公開日 2019-11-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural determinants of microtubule minus end preference in CAMSAP CKK domains. Nat Commun, 10, 2019

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