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2A9I
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Molecular Structure of the Interleukin-1 Receptor-Associated Kinase-4 Death Domain
分子名称: Interleukin-1 receptor-associated kinase-4, MANGANESE (II) ION
著者Lasker, M.V, Gajjar, M.M, Nair, S.K.
登録日2005-07-11
公開日2005-10-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Cutting Edge: Molecular Structure of the IL-1R-Associated Kinase-4 Death Domain and Its Implications for TLR Signaling.
J.Immunol., 175, 2005
1VWI
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STREPTAVIDIN-CYCLO-[5-S-VALERAMIDE-HPQGPPC]K-NH2, PH 1.5, I222 COMPLEX
分子名称: PENTANOIC ACID, PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN
著者Katz, B.A, Cass, R.T.
登録日1997-03-03
公開日1998-03-18
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
1VWN
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STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 4.8
分子名称: PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN
著者Katz, B.A, Cass, R.T.
登録日1997-03-03
公開日1998-03-18
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
1VWJ
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STREPTAVIDIN-CYCLO-[5-S-VALERAMIDE-HPQGPPC]K-NH2, PH 2.5, I222 COMPLEX
分子名称: PENTANOIC ACID, PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN
著者Katz, B.A, Cass, R.T.
登録日1997-03-03
公開日1998-03-18
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
1VWE
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STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 3.6
分子名称: PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN
著者Katz, B.A, Cass, R.T.
登録日1997-03-03
公開日1998-03-18
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
4I4J
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The structure of SgcE10, the ACP-polyene thioesterase involved in C-1027 biosynthesis
分子名称: 1,2-ETHANEDIOL, ACP-polyene thioesterase, D(-)-TARTARIC ACID, ...
著者Kim, Y, Bigelow, L, Bearden, J, Babnigg, J, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-11-27
公開日2012-12-12
最終更新日2022-05-04
実験手法X-RAY DIFFRACTION (2.784 Å)
主引用文献Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis.
Acs Omega, 2, 2017
4S21
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Crystal structure of the photosensory core module of bacteriophytochrome RPA3015 from R. palustris
分子名称: BILIVERDINE IX ALPHA, Bacteriophytochrome (Light-regulated signal transduction histidine kinase), PhyB1
著者Yang, X, Stojkovi, E.A, Ozarowski, W.B, Moffat, K.
登録日2015-01-17
公開日2015-07-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Light Signaling Mechanism of Two Tandem Bacteriophytochromes.
Structure, 23, 2015
4I6W
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3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate
分子名称: (3S)-3-hydroxy-3-methyl-5-sulfanylpentanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, GLYCEROL, ...
著者Steussy, C.N, Stauffacher, C.V, Schmidt, T, Burgner II, J.W, Rodwell, V.W, Wrensford, L.V, Critchelow, C.J, Min, J.
登録日2012-11-30
公開日2013-07-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
4I3A
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Structures of PR1 and PR2 intermediates from time-resolved laue crystallography collected at 14ID-B, APS
分子名称: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein
著者Jung, Y.O, Lee, J.H, Kim, J, Schmidt, M, Vukica, S, Moffat, K, Ihee, H.
登録日2012-11-26
公開日2013-03-20
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Volume-conserving trans-cis isomerization pathways in photoactive yellow protein visualized by picosecond X-ray crystallography
NAT.CHEM., 5, 2013
4TX3
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Complex of the X-domain and OxyB from Teicoplanin Biosynthesis
分子名称: 1,2-ETHANEDIOL, OxyB protein, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Peschke, M, Haslinger, K, Cryle, M.J.
登録日2014-07-02
公開日2015-02-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis.
Nature, 521, 2015
4JK1
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X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with Guanosine tetraphosphate (ppGpp)
分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ...
著者Murakami, K.S.
登録日2013-03-09
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Differential regulation by ppGpp versus pppGpp in Escherichia coli.
Nucleic Acids Res., 41, 2013
2A1A
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PKR kinase domain-eIF2alpha Complex
分子名称: Eukaryotic translation initiation factor 2 alpha subunit, Interferon-induced, double-stranded RNA-activated protein kinase
著者Dar, A.C, Dever, T.E, Sicheri, F.
登録日2005-06-19
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR.
Cell(Cambridge,Mass.), 122, 2005
2A2S
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Crystal Structure of Human Glutathione Transferase in complex with S-nitrosoglutathione in the absence of reducing agent
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-5-[1-(CARBOXYLATOMETHYLCARBAMOYL)-2-NITROSOSULFANYL-ETHYL]AMINO-5-OXO-PENTANOATE, CALCIUM ION, ...
著者Parker, L.J, Morton, C.J, Adams, J.J, Parker, M.W.
登録日2005-06-23
公開日2006-06-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Calorimetric and structural studies of the nitric oxide carrier S-nitrosoglutathione bound to human glutathione transferase P1-1
Protein Sci., 15, 2006
4JT0
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Yeast 20S proteasome in complex with the dimerized linear mimetic of TMC-95A - yCP:4a
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ...
著者Desvergne, A, Genin, E, Marechal, X, Gallastegui, N, Dufau, L, Richy, N, Groll, M, Vidal, J, Reboud-Ravaux, M.
登録日2013-03-22
公開日2013-05-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome.
J.Med.Chem., 56, 2013
2A7P
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Crystal Structure of the G81A mutant of the Active Chimera of (S)-Mandelate Dehydrogenase in complex with its substrate 3-indolelactate
分子名称: (S)-Mandelate Dehydrogenase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(INDOL-3-YL) LACTATE, ...
著者Sukumar, N, Xu, Y, Mitra, B, Mathews, F.S.
登録日2005-07-05
公開日2006-07-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of the G81A mutant form of the active chimera of (S)-mandelate dehydrogenase and its complex with two of its substrates.
Acta Crystallogr.,Sect.D, 65, 2009
2A8K
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Structural and Mutational Studies of the Catalytic Domain of Colicin E5a tRNA-Specific Ribonuclease
分子名称: CALCIUM ION, Colicin E5
著者Lin, Y.L, Elias, Y, Huang, R.H.
登録日2005-07-08
公開日2005-09-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and mutational studies of the catalytic domain of colicin E5: A tRNA-specific ribonuclease
Biochemistry, 44, 2005
2AAS
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HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF RIBONUCLEASE A IN SOLUTION BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
分子名称: RIBONUCLEASE A
著者Santoro, J, Gonzalez, C, Bruix, M, Neira, J.L, Nieto, J.L, Herranz, J, Rico, M.
登録日1992-11-20
公開日1994-01-31
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献High-resolution three-dimensional structure of ribonuclease A in solution by nuclear magnetic resonance spectroscopy.
J.Mol.Biol., 229, 1993
2AB4
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Dissecting the Roles of a Strictly Conserved Tyrosine in Substrate Recognition and Catalysis by Pseudouridine 55 Synthase
分子名称: 5'-R(*CP*CP*AP*CP*GP*GP*UP*(FHU)P*CP*GP*AP*AP*UP*CP*CP*GP*UP*GP*GP*C)-3', ZINC ION, tRNA pseudouridine synthase B
著者Phannachet, K, Elias, Y, Huang, R.H.
登録日2005-07-14
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Dissecting the roles of a strictly conserved tyrosine in substrate recognition and catalysis by pseudouridine 55 synthase.
Biochemistry, 44, 2005
2AEW
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A model for growth hormone receptor activation based on subunit rotation within a receptor dimer
分子名称: Growth hormone receptor
著者Adams, J.J, McKinstry, W.J, Parker, M.W, Waters, M.J.
登録日2005-07-24
公開日2005-11-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Model for growth hormone receptor activation based on subunit rotation within a receptor dimer.
Nat.Struct.Mol.Biol., 12, 2005
2A0Q
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Structure of thrombin in 400 mM potassium chloride
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, CHLORIDE ION, POTASSIUM ION, ...
著者Papaconstantinou, M, Carrell, C.J, Pineda, A.O, Bobofchak, K.M, Mathews, F.S, Flordellis, C.S, Maragoudakis, M.E, Tsopanoglou, N.E, di Cera, E.
登録日2005-06-16
公開日2005-07-12
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Thrombin Functions through Its RGD Sequence in a Non-canonical Conformation.
J.Biol.Chem., 280, 2005
2A3F
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Crystal structure of nitrophorin 2 aqua complex
分子名称: Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE
著者Weichsel, A, Berry, R.E, Walker, F.A, Montfort, W.R.
登録日2005-06-24
公開日2006-06-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus.
To be Published
2A6H
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BU of 2a6h by Molmil
Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Temiakov, D, Zenkin, N, Vassylyeva, M.N, Perederina, A, Tahirov, T.H, Savkina, M, Zorov, S, Nikiforov, V, Igarashi, N, Matsugaki, N, Wakatsuki, S, Severinov, K, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-02
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of transcription inhibition by antibiotic streptolydigin.
Mol.Cell, 19, 2005
1Z7E
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Crystal structure of full length ArnA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID, protein ArnA
著者Gatzeva-Topalova, P.Z, May, A.P, Sousa, M.C.
登録日2005-03-24
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and Mechanism of ArnA: Conformational Change Implies Ordered Dehydrogenase Mechanism in Key Enzyme for Polymyxin Resistance
Structure, 13, 2005
4IRB
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Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4
分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
著者Schormann, N, Zhukovskaya, N, Sartmatova, D, Nuth, M, Ricciardi, R.P, Chattopadhyay, D.
登録日2013-01-14
公開日2014-02-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mutations at the dimer interface affect both function and structure of the Vaccinia virus uracil DNA glycosylase
To be Published
1ZM3
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Structure of the apo eEF2-ETA complex
分子名称: Elongation factor 2, exotoxin A
著者Joergensen, R, Merrill, A.R, Yates, S.P, Marquez, V.E, Schwan, A.L, Boesen, T, Andersen, G.R.
登録日2005-05-10
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
Nature, 436, 2005

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