1UKI
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![BU of 1uki by Molmil](/molmil-images/mine/1uki) | Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 | 分子名称: | 11-mer peptide from C-jun-amino-terminal kinase interacting protein 1, 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE, mitogen-activated protein kinase 8 isoform 4 | 著者 | Heo, Y.-S, Kim, Y.K, Sung, B.-J, Lee, H.S, Lee, J.I, Seo, C.I, Park, S.-Y, Kim, J.H, Hyun, Y.-L, Jeon, Y.H, Ro, S, Lee, T.G, Cho, J.M, Hwang, K.Y, Yang, C.-H. | 登録日 | 2003-08-23 | 公開日 | 2004-08-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 Embo J., 23, 2004
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6IB0
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![BU of 6ib0 by Molmil](/molmil-images/mine/6ib0) | The structure of MKK7 in complex with the covalent 4-amino-pyrazolopyrimidine 3a | 分子名称: | 1-[(3~{R})-3-(4-azanyl-3-ethynyl-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl]prop-2-en-1-one, Dual specificity mitogen-activated protein kinase kinase 7, TETRAETHYLENE GLYCOL | 著者 | Wolle, P, Hardick, J, Mueller, M.P, Rauh, D. | 登録日 | 2018-11-28 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Targeting the MKK7-JNK (Mitogen-Activated Protein Kinase Kinase 7-c-Jun N-Terminal Kinase) Pathway with Covalent Inhibitors. J.Med.Chem., 62, 2019
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6IB2
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![BU of 6ib2 by Molmil](/molmil-images/mine/6ib2) | The structure of MKK7 in complex with the covalent 4-amino-pyrazolopyrimidine 4a | 分子名称: | 1-[(3~{R})-3-[4-azanyl-3-[1-(4-ethanoylphenyl)-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one, Dual specificity mitogen-activated protein kinase kinase 7 | 著者 | Wolle, P, Hardick, J, Mueller, M.P, Rauh, D. | 登録日 | 2018-11-28 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Targeting the MKK7-JNK (Mitogen-Activated Protein Kinase Kinase 7-c-Jun N-Terminal Kinase) Pathway with Covalent Inhibitors. J.Med.Chem., 62, 2019
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5YK6
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![BU of 5yk6 by Molmil](/molmil-images/mine/5yk6) | Crystal Structure of Mmm1 | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, Maintenance of mitochondrial morphology protein 1 | 著者 | Jeong, H, Park, J, Lee, C. | 登録日 | 2017-10-12 | 公開日 | 2018-01-10 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5YK7
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![BU of 5yk7 by Molmil](/molmil-images/mine/5yk7) | Crystal Structure of Mdm12-Mmm1 complex | 分子名称: | Maintenance of mitochondrial morphology protein 1, Mitochondrial distribution and morphology protein 12, PHOSPHATE ION | 著者 | Jeong, H, Park, J, Lee, C. | 登録日 | 2017-10-12 | 公開日 | 2018-01-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.799 Å) | 主引用文献 | Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2CKX
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5DBU
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![BU of 5dbu by Molmil](/molmil-images/mine/5dbu) | |
5B26
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![BU of 5b26 by Molmil](/molmil-images/mine/5b26) | Crystal structure of mouse SEL1L | 分子名称: | Protein sel-1 homolog 1 | 著者 | Jeong, H, Lee, C. | 登録日 | 2016-01-09 | 公開日 | 2016-04-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway Sci Rep, 6, 2016
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5DBT
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5H60
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![BU of 5h60 by Molmil](/molmil-images/mine/5h60) | Structure of Transferase mutant-C23S,C199S | 分子名称: | MANGANESE (II) ION, Transferase, URIDINE-5'-DIPHOSPHATE | 著者 | Park, J.B, Yoo, Y, Kim, J. | 登録日 | 2016-11-10 | 公開日 | 2017-12-20 | 最終更新日 | 2018-10-31 | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | 主引用文献 | Structural basis for arginine glycosylation of host substrates by bacterial effector proteins. Nat Commun, 9, 2018
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5H61
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5H5Y
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![BU of 5h5y by Molmil](/molmil-images/mine/5h5y) | |
5H63
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![BU of 5h63 by Molmil](/molmil-images/mine/5h63) | Structure of Transferase mutant-C23S,C199S | 分子名称: | MANGANESE (II) ION, Transferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | 著者 | Park, J.B, Yoo, Y, Kim, J. | 登録日 | 2016-11-10 | 公開日 | 2017-12-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural basis for arginine glycosylation of host substrates by bacterial effector proteins. Nat Commun, 9, 2018
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5H62
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![BU of 5h62 by Molmil](/molmil-images/mine/5h62) | Structure of Transferase mutant-C23S,C199S | 分子名称: | 1,2-ETHANEDIOL, MANGANESE (II) ION, Transferase, ... | 著者 | Park, J.B, Yoo, Y, Kim, J. | 登録日 | 2016-11-10 | 公開日 | 2017-12-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structural basis for arginine glycosylation of host substrates by bacterial effector proteins. Nat Commun, 9, 2018
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6KBN
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6KBM
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![BU of 6kbm by Molmil](/molmil-images/mine/6kbm) | Crystal structure of Vac8 bound to Atg13 | 分子名称: | Autophagy-related protein 13, Vacuolar protein 8 | 著者 | Park, J, Lee, C. | 登録日 | 2019-06-25 | 公開日 | 2019-11-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.902 Å) | 主引用文献 | Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways. Autophagy, 16, 2020
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8J0J
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![BU of 8j0j by Molmil](/molmil-images/mine/8j0j) | AtSLAC1 8D mutant in closed state | 分子名称: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein | 著者 | Lee, Y, Lee, S. | 登録日 | 2023-04-11 | 公開日 | 2023-11-22 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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8J1E
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![BU of 8j1e by Molmil](/molmil-images/mine/8j1e) | AtSLAC1 in open state | 分子名称: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein | 著者 | Lee, Y, Lee, S. | 登録日 | 2023-04-12 | 公開日 | 2023-11-22 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | 主引用文献 | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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8GW7
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![BU of 8gw7 by Molmil](/molmil-images/mine/8gw7) | AtSLAC1 6D mutant in open state | 分子名称: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | 著者 | Lee, Y, Lee, S. | 登録日 | 2022-09-16 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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8GW6
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![BU of 8gw6 by Molmil](/molmil-images/mine/8gw6) | AtSLAC1 6D mutant in closed state | 分子名称: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | 著者 | Lee, Y, Lee, S. | 登録日 | 2022-09-16 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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6J10
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![BU of 6j10 by Molmil](/molmil-images/mine/6j10) | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly | 分子名称: | 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one, Capsid protein | 著者 | Park, S, Jin, M.S, Cho, Y, Kang, J, Kim, S, Park, M, Park, H, Kim, J, Park, S, Hwang, J, Kim, Y, Kim, Y.J. | 登録日 | 2018-12-27 | 公開日 | 2019-04-17 | 最終更新日 | 2019-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly. Nat Commun, 10, 2019
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6I0C
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![BU of 6i0c by Molmil](/molmil-images/mine/6i0c) | Human butyrylcholinesterase in complex with the R enantiomer of a chlorotacrine-tryptophan multi-target inhibitor. | 分子名称: | (2~{R})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Brazzolotto, X, Nachon, F. | 登録日 | 2018-10-25 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.675 Å) | 主引用文献 | Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease. Eur.J.Med.Chem., 168, 2019
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6K1D
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6K1C
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6K18
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![BU of 6k18 by Molmil](/molmil-images/mine/6k18) | Crystal structure of EXD2 exonuclease domain soaked in Mn | 分子名称: | Exonuclease 3'-5' domain-containing protein 2, MANGANESE (II) ION | 著者 | Park, J, Lee, C. | 登録日 | 2019-05-10 | 公開日 | 2019-05-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res., 47, 2019
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