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1YLD
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BU of 1yld by Molmil
Trypsin/BPTI complex mutant
分子名称: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ...
著者Brown, C.K, Ohlendorf, D.H.
登録日2005-01-19
公開日2006-04-25
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Partially folded bovine pancreatic trypsin inhibitor analogues attain fully native structures when co-crystallized with S195A rat trypsin
J.Mol.Biol., 375, 2008
5MPD
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BU of 5mpd by Molmil
26S proteasome in presence of ATP (s1)
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit RPN10, ...
著者Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E.
登録日2016-12-16
公開日2017-03-08
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into the functional cycle of the ATPase module of the 26S proteasome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4H37
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BU of 4h37 by Molmil
Crystal structure of a voltage-gated K+ channel pore domain in a closed state in lipid membranes
分子名称: Lmo2059 protein, POTASSIUM ION
著者Santos, J.S, Asmar-Rovira, G.A, Han, G.W, Liu, W, Syeda, R, Cherezov, V, Baker, K.A, Stevens, R.C, Montal, M.
登録日2012-09-13
公開日2012-11-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes.
J.Biol.Chem., 287, 2012
7AQO
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BU of 7aqo by Molmil
yeast THO-Sub2 complex dimer
分子名称: BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ...
著者Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E.
登録日2020-10-22
公開日2020-12-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
1YLC
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BU of 1ylc by Molmil
Trypsin/BPTI complex mutant
分子名称: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ...
著者Brown, C.K, Ohlendorf, D.H.
登録日2005-01-19
公開日2006-04-25
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Partially folded bovine pancreatic trypsin inhibitor analogues attain fully native structures when co-crystallized with S195A rat trypsin
J.Mol.Biol., 375, 2008
1YLH
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BU of 1ylh by Molmil
Crystal Structure of Phosphoenolpyruvate Carboxykinase from Actinobaccilus succinogenes in Complex with Manganese and Pyruvate
分子名称: (2S,3S)-2,3-DIHYDROXY-4-SULFANYLBUTANE-1-SULFONATE, BETA-MERCAPTOETHANOL, FORMIC ACID, ...
著者Leduc, Y.A, Prasad, L, Laivenieks, M, Zeikus, J.G, Delbaere, L.T.
登録日2005-01-19
公開日2005-06-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of PEP carboxykinase from the succinate-producing Actinobacillus succinogenes: a new conserved active-site motif.
Acta Crystallogr.,Sect.D, 61, 2005
3OKH
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BU of 3okh by Molmil
Crystal structure of human FXR in complex with 2-(4-chlorophenyl)-1-[(1S)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1H-benzimidazole-6-carboxylic acid
分子名称: 2-(4-chlorophenyl)-1-[(1S)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1H-benzimidazole-6-carboxylic acid, Bile acid receptor, peptide of Nuclear receptor coactivator 1
著者Rudolph, M.G.
登録日2010-08-25
公開日2010-12-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes
Bioorg.Med.Chem.Lett., 21, 2010
5MD2
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BU of 5md2 by Molmil
The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=5, twist=-6
分子名称: Capsid protein p24 C-terminal domain, Capsid protein p24 N-terminal domain
著者Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G.
登録日2016-11-10
公開日2016-12-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science, 354, 2016
5MDC
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BU of 5mdc by Molmil
The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=17, twist=-12
分子名称: Gag protein
著者Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G.
登録日2016-11-10
公開日2016-12-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.4 Å)
主引用文献The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science, 354, 2016
1YO8
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BU of 1yo8 by Molmil
Structure of the C-terminal domain of human thrombospondin-2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Carlson, C.B, Bernstein, D.A, Annis, D.S, Misenheimer, T.M, Hannah, B.A, Mosher, D.F, Keck, J.L.
登録日2005-01-26
公開日2005-09-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the calcium-rich signature domain of human thrombospondin-2
Nat.Struct.Mol.Biol., 12, 2005
3ME6
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BU of 3me6 by Molmil
Crystal structure of cytochrome 2B4 in complex with the anti-platelet drug clopidogrel
分子名称: Clopidogrel, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
著者Gay, S.C, Roberts, A.G, Maekawa, K, Talakad, J.C, Hong, W.X, Zhang, Q, Stout, C.D, Halpert, J.R.
登録日2010-03-31
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel.
Biochemistry, 49, 2010
3MG4
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BU of 3mg4 by Molmil
Structure of yeast 20S proteasome with Compound 1
分子名称: (2S)-2-amino-N-[(1S)-1-({(1S)-1-[(4-methylbenzyl)carbamoyl]-3-phenylpropyl}carbamoyl)-3-phenylpropyl]-4-phenylbutanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ...
著者Sintchak, M.D.
登録日2010-04-05
公開日2011-04-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit.
Biochem.J., 430, 2010
1YN4
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BU of 1yn4 by Molmil
Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens
分子名称: EapH1, ZINC ION
著者Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J.
登録日2005-01-23
公開日2005-03-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
1YNB
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BU of 1ynb by Molmil
crystal structure of genomics APC5600
分子名称: hypothetical protein AF1432
著者Dong, A, Skarina, T, Savchenko, A, Pai, E.F, Joachimiak, A, Edwards, A, Midwest Center for Structural Genomics (MCSG)
登録日2005-01-24
公開日2005-03-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of genomics AF1432 by Sulfur SAD methods
To be Published
1YNN
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BU of 1ynn by Molmil
Taq RNA polymerase-rifampicin complex
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A.
登録日2005-01-24
公開日2005-03-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
1YQP
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BU of 1yqp by Molmil
T268N mutant cytochrome domain of flavocytochrome P450 BM3
分子名称: Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE
著者Clark, J.P, Miles, C.S, Mowat, C.G, Walkinshaw, M.D, Reid, G.A, Daff, S.N, Chapman, S.K.
登録日2005-02-02
公開日2006-01-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The role of Thr268 and Phe393 in cytochrome P450 BM3.
J.Inorg.Biochem., 100, 2006
4IK3
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BU of 4ik3 by Molmil
High resolution structure of GCaMP3 at pH 8.5
分子名称: CALCIUM ION, RCaMP, Green fluorescent protein
著者Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G.
登録日2012-12-25
公開日2014-01-29
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.007 Å)
主引用文献Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
3M5M
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BU of 3m5m by Molmil
Avoiding drug resistance against HCV NS3/4A protease inhibitors
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FDEMEEC Peptide, NS3/4A, ...
著者Schiffer, C.A, Romano, K.P.
登録日2010-03-12
公開日2010-11-24
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MM0
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BU of 3mm0 by Molmil
Crystal structure of chimeric avidin
分子名称: Avidin, Avidin-related protein 4/5
著者Livnah, O, Eisenberg-Domovich, Y, Maatta, J.A.E, Kulomaa, M.S, Hytonen, V.P, Nordlund, H.R.
登録日2010-04-19
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Chimeric avidin shows stability against harsh chemical conditions-biochemical analysis and 3D structure.
Biotechnol.Bioeng., 108, 2011
3HUG
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BU of 3hug by Molmil
Crystal structure of Mycobacterium tuberculosis anti-sigma factor RslA in complex with -35 promoter binding domain of sigL
分子名称: PROBABLE CONSERVED MEMBRANE PROTEIN, RNA polymerase sigma factor, SULFATE ION, ...
著者Thakur, K.G, Gopal, B.
登録日2009-06-14
公開日2010-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural and biochemical bases for the redox sensitivity of Mycobacterium tuberculosis RslA
J.Mol.Biol., 397, 2010
4IFD
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BU of 4ifd by Molmil
Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, Exosome complex component CSL4, ...
著者Makino, D.L, Conti, E.
登録日2012-12-14
公開日2013-02-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex.
Nature, 495, 2013
3HTO
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BU of 3hto by Molmil
the hemagglutinin structure of an avian H1N1 influenza A virus
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Wang, G, Li, A, Zhang, Q, Wu, C, Zhang, R, Cai, Q, Song, W, Yuen, K.-Y.
登録日2009-06-12
公開日2009-08-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The hemagglutinin structure of an avian H1N1 influenza A virus
Virology, 392, 2009
3HTY
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BU of 3hty by Molmil
Crystal structure of a lipocalin-like protein (BT_0869) from Bacteroides thetaiotaomicron VPI-5482 at 1.95 A resolution
分子名称: GLYCEROL, SULFATE ION, hypothetical protein BT_0869
著者Joint Center for Structural Genomics, Joint Center for Structural Genomics (JCSG)
登録日2009-06-12
公開日2009-07-07
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of hypothetical protein BT_0869 from Bacteroides thetaiotaomicron VPI-5482 (NP_809782.1) at 1.95 A resolution
To be Published
4INR
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BU of 4inr by Molmil
Yeast 20S proteasome in complex with the vinyl sulfone LU102
分子名称: N3Phe-Leu-Leu-Phe(4-NH2CH2)-methyl vinyl sulfone, bound form, Proteasome component C1, ...
著者Geurink, P.P, van der Linden, W.A, Mirabella, A.C, Gallastegui, N, de Bruin, G, Blom, A.E.M, Voges, M.J, Mock, E.D, Florea, B.I, van der Marel, G.A, Driessen, C, van der Stelt, M, Groll, M, Overkleeft, H.S, Kisselev, A.F.
登録日2013-01-06
公開日2013-01-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites.
J.Med.Chem., 56, 2013
4INT
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BU of 4int by Molmil
Yeast 20S proteasome in complex with the vinyl sulfone LU122
分子名称: HMB-Val-Ser-Phe(4-NH2CH2)-methyl vinyl sulfone, bound form, Proteasome component C1, ...
著者Geurink, P.P, van der Linden, W.A, Mirabella, A.C, Gallastegui, N, de Bruin, G, Blom, A.E.M, Voges, M.J, Mock, E.D, Florea, B.I, van der Marel, G.A, Driessen, C, van der Stelt, M, Groll, M, Overkleeft, H.S, Kisselev, A.F.
登録日2013-01-06
公開日2013-01-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites.
J.Med.Chem., 56, 2013

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