7HVP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7hvp by Molmil](/molmil-images/mine/7hvp) | X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A COMPLEX BETWEEN A SYNTHETIC PROTEASE OF HUMAN IMMUNODEFICIENCY VIRUS 1 AND A SUBSTRATE-BASED HYDROXYETHYLAMINE INHIBITOR | 分子名称: | HIV-1 PROTEASE, INHIBITOR ACE-SER-LEU-ASN-PHE-PSI(CH(OH)-CH2N)-PRO-ILE VME (JG-365) | 著者 | Swain, A.L, Miller, M.M, Green, J, Rich, D.H, Schneider, J, Kent, S.B.H, Wlodawer, A. | 登録日 | 1990-09-13 | 公開日 | 1993-07-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor. Proc.Natl.Acad.Sci.USA, 87, 1990
|
|
3KLY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kly by Molmil](/molmil-images/mine/3kly) | |
5ZHP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zhp by Molmil](/molmil-images/mine/5zhp) | M3 muscarinic acetylcholine receptor in complex with a selective antagonist | 分子名称: | (1R,2R,4S,5S,7s)-7-({[4-fluoro-2-(thiophen-2-yl)phenyl]carbamoyl}oxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]nonan-9-ium, CITRIC ACID, HEXAETHYLENE GLYCOL, ... | 著者 | Liu, H, Hofmann, J, Fish, I, Schaake, B, Eitel, K, Bartuschat, A, Kaindl, J, Rampp, H, Banerjee, A, Hubner, H, Clark, M.J, Vincent, S.G, Fisher, J, Heinrich, M, Hirata, K, Liu, X, Sunahara, R.K, Shoichet, B.K, Kobilka, B.K, Gmeiner, P. | 登録日 | 2018-03-13 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
5GIV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5giv by Molmil](/molmil-images/mine/5giv) | Crystal structure of M32 carboxypeptidase from Deinococcus radiodurans R1 | 分子名称: | ACETATE ION, Carboxypeptidase 1, ZINC ION | 著者 | Sharma, B, Singh, R, Yadav, P, Ghosh, B, Kumar, A, Jamdar, S.N, Makde, R.D. | 登録日 | 2016-06-25 | 公開日 | 2017-07-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Active site gate of M32 carboxypeptidases illuminated by crystal structure and molecular dynamics simulations Biochim. Biophys. Acta, 1865, 2017
|
|
4PG6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pg6 by Molmil](/molmil-images/mine/4pg6) | |
6HQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hq1 by Molmil](/molmil-images/mine/6hq1) | |
6GWC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gwc by Molmil](/molmil-images/mine/6gwc) | Tubulin:iE5 alphaRep complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALPHA-TUBULIN, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Gigant, B, Campanacci, V. | 登録日 | 2018-06-22 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Selection and Characterization of Artificial Proteins Targeting the Tubulin alpha Subunit. Structure, 27, 2019
|
|
2WLO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wlo by Molmil](/molmil-images/mine/2wlo) | POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM | 分子名称: | POTASSIUM CHANNEL, POTASSIUM ION | 著者 | Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M. | 登録日 | 2009-06-24 | 公開日 | 2010-06-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (4.036 Å) | 主引用文献 | Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels. Cell(Cambridge,Mass.), 141, 2010
|
|
5DIE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5die by Molmil](/molmil-images/mine/5die) | Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-7a-methyl-5-(2,3,5-trifluoro-4-hydroxyphenyl)octahydro-1H-inden-1-ol | 分子名称: | (1S,3aR,5S,7aS)-7a-methyl-5-(2,3,5-trifluoro-4-hydroxyphenyl)octahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | 登録日 | 2015-08-31 | 公開日 | 2016-05-04 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016
|
|
6H02
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6h02 by Molmil](/molmil-images/mine/6h02) | |
6I33
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6i33 by Molmil](/molmil-images/mine/6i33) | Crystal structure of human glycine decarboxylase (P-protein) | 分子名称: | 1,2-ETHANEDIOL, BICARBONATE ION, Glycine dehydrogenase (decarboxylating), ... | 著者 | Van Laer, B, Kapp, U, Leonard, G, Mueller-Dieckmann, C. | 登録日 | 2018-11-05 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights in human glycine decarboxylase and comparison with the Neanderthal variant To Be Published
|
|
2WRZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wrz by Molmil](/molmil-images/mine/2wrz) | Crystal structure of an arabinose binding protein with designed serotonin binding site in open, ligand-free state | 分子名称: | L-ARABINOSE-BINDING PERIPLASMIC PROTEIN | 著者 | Schreier, B, Stumpp, C, Wiesner, S, Hocker, B. | 登録日 | 2009-09-03 | 公開日 | 2009-10-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Computational Design of Ligand Binding is not a Solved Problem Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
6C48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6c48 by Molmil](/molmil-images/mine/6c48) | Crystal structure of B-Myb-LIN9-LIN52 complex | 分子名称: | Myb-related protein B, Protein lin-52 homolog, Protein lin-9 homolog, ... | 著者 | Guiley, K.Z, Tripathi, S.M, Rubin, S.M. | 登録日 | 2018-01-11 | 公開日 | 2018-09-19 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structural mechanism of Myb-MuvB assembly. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
2X05
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2x05 by Molmil](/molmil-images/mine/2x05) | Inhibition of the exo-beta-D-glucosaminidase CsxA by a glucosamine- configured castanospermine and an amino-australine analogue | 分子名称: | AMINO-CASTANOSPERMINE, CADMIUM ION, EXO-BETA-D-GLUCOSAMINIDASE | 著者 | Pluvinage, B, Ghinet, M.G, Brzezinski, R, Boraston, A.B, Stubbs, K.A. | 登録日 | 2009-12-05 | 公開日 | 2009-12-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Inhibition of the Exo-Beta-D-Glucosaminidase Csxa by a Glucosamine-Configured Castanospermine and an Amino-Australine Analogue. Org.Biomol.Chem., 7, 2009
|
|
5VVB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vvb by Molmil](/molmil-images/mine/5vvb) | Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(2-(((2-Aminoquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-{[(2-aminoquinolin-7-yl)methyl]amino}ethyl)-2-methylbenzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ... | 著者 | Li, H, Poulos, T.L. | 登録日 | 2017-05-19 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J. Med. Chem., 60, 2017
|
|
5VWI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vwi by Molmil](/molmil-images/mine/5vwi) | |
1EUY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1euy by Molmil](/molmil-images/mine/1euy) | GLUTAMINYL-TRNA SYNTHETASE COMPLEXED WITH A TRNA MUTANT AND AN ACTIVE SITE INHIBITOR | 分子名称: | 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, GLUTAMINYL TRNA, GLUTAMINYL-TRNA SYNTHETASE | 著者 | Sherlin, L.D, Bullock, T.L, Newberry, K.J, Lipman, R.S.A, Hou, Y.-M, Beijer, B, Sproat, B.S, Perona, J.J. | 登録日 | 2000-04-19 | 公開日 | 2000-06-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases. J.Mol.Biol., 299, 2000
|
|
5VQP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vqp by Molmil](/molmil-images/mine/5vqp) | Crystal structure of human pro-TGF-beta1 | 分子名称: | Transforming growth factor beta-1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Zhao, B, Xu, S, Dong, X, Lu, C, Springer, T.A. | 登録日 | 2017-05-09 | 公開日 | 2017-11-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Prodomain-growth factor swapping in the structure of pro-TGF-beta 1. J. Biol. Chem., 293, 2018
|
|
4PH9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ph9 by Molmil](/molmil-images/mine/4ph9) | The structure of Ibuprofen bound to cyclooxygenase-2 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Orlando, B.J, Lucido, M.J, Malkowski, M.G. | 登録日 | 2014-05-05 | 公開日 | 2014-11-26 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | The structure of ibuprofen bound to cyclooxygenase-2. J.Struct.Biol., 189, 2015
|
|
5BYN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5byn by Molmil](/molmil-images/mine/5byn) | Canavalia maritima lectin complexed with synthetic selenoamino acid | 分子名称: | (4R)-4-{[(S)-tert-butoxy(hydroxy)methyl]amino}-5-[(1S)-cyclohex-2-en-1-ylselanyl]pentane-1,1-diol, 1,2-ETHANEDIOL, CADMIUM ION, ... | 著者 | Nobrega, R.B, Silva-Filho, J.C, Kawasoko, C.Y, Rodrigues, O.E.D, Schwab, R.S, Braga, A.L, Delatorre, P, Cavada, B.S. | 登録日 | 2015-06-10 | 公開日 | 2015-11-18 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.651 Å) | 主引用文献 | Canavalia maritima lectin complexed with synthetic selenoamino acid To Be Published
|
|
4PG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pg5 by Molmil](/molmil-images/mine/4pg5) | |
7JH4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jh4 by Molmil](/molmil-images/mine/7jh4) | Crystal structure of NAD(P)H-flavin oxidoreductase (NfoR) from S. aureus complexed with reduced FMN and NAD+ | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, NAD(P)H-dependent oxidoreductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Zheng, Y, O'Neill, A.G, Beaupre, B.A, Liu, D, Moran, G.R. | 登録日 | 2020-07-20 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | NfoR: Chromate Reductase or Flavin Mononucleotide Reductase? Appl.Environ.Microbiol., 86, 2020
|
|
5C0Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c0q by Molmil](/molmil-images/mine/5c0q) | |
7M5M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m5m by Molmil](/molmil-images/mine/7m5m) | PCNA bound to peptide mimetic | 分子名称: | N-BUTANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen | 著者 | Vandborg, B.A, Bruning, J.B. | 登録日 | 2021-03-24 | 公開日 | 2021-08-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
|
|
3EH8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eh8 by Molmil](/molmil-images/mine/3eh8) | |