5K9T
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8DXR
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![BU of 8dxr by Molmil](/molmil-images/mine/8dxr) | Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 5 | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | 登録日 | 2022-08-02 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
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8DXO
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![BU of 8dxo by Molmil](/molmil-images/mine/8dxo) | Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 2 | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | 登録日 | 2022-08-02 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
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8DXP
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![BU of 8dxp by Molmil](/molmil-images/mine/8dxp) | Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 3 | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | 登録日 | 2022-08-02 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
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8DXQ
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![BU of 8dxq by Molmil](/molmil-images/mine/8dxq) | Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 4 | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | 登録日 | 2022-08-02 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
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8DXN
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![BU of 8dxn by Molmil](/molmil-images/mine/8dxn) | Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 1 | 分子名称: | Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A | 著者 | Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E. | 登録日 | 2022-08-02 | 公開日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife, 12, 2023
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2YSU
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4U72
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![BU of 4u72 by Molmil](/molmil-images/mine/4u72) | Crystal structure of 4-phenylimidazole bound form of human indoleamine 2,3-dioxygenase (A260G mutant) | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 4-PHENYL-1H-IMIDAZOLE, Indoleamine 2,3-dioxygenase 1, ... | 著者 | Sugimoto, H, Horitani, M, Kometani, E, Shiro, Y. | 登録日 | 2014-07-30 | 公開日 | 2015-09-02 | 最終更新日 | 2020-01-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformation and Mobility of Active Site Loop is Critical for Substrate Binding and Inhibition in Human Indoleamine 2,3-Dioxygenase to be published
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4UHJ
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4UHS
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4UHK
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4UF0
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![BU of 4uf0 by Molmil](/molmil-images/mine/4uf0) | Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid. | 分子名称: | 1,2-ETHANEDIOL, 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid, FE (II) ION, ... | 著者 | Srikannathasan, V, Johansson, C, Gileadi, C, Tobias, K, Kopec, J, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U. | 登録日 | 2014-12-22 | 公開日 | 2015-01-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development. Nat.Chem.Biol., 12, 2016
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4UHT
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4V48
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![BU of 4v48 by Molmil](/molmil-images/mine/4v48) | Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the initiation-like state of E. coli 70S ribosome | 分子名称: | 16S RIBOSOMAL RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Gao, H, Sengupta, J, Valle, M, Korostelev, A, Eswar, N, Stagg, S.M, Van Roey, P, Agrawal, R.K, Harvey, S.T, Sali, A, Chapman, M.S, Frank, J. | 登録日 | 2003-05-06 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (11.5 Å) | 主引用文献 | Study of the structural dynamics of the E. coli 70S ribosome using real space refinement Cell(Cambridge,Mass.), 113, 2003
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4U74
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![BU of 4u74 by Molmil](/molmil-images/mine/4u74) | Crystal structure of 4-phenylimidazole bound form of human indoleamine 2,3-dioxygenase (G262A mutant) | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 4-PHENYL-1H-IMIDAZOLE, Indoleamine 2,3-dioxygenase 1, ... | 著者 | Sugimoto, H, Horitani, M, Kometani, E, Shiro, Y. | 登録日 | 2014-07-30 | 公開日 | 2015-09-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Conformation and Mobility of Active Site Loop is Critical for Substrate Binding and Inhibition in Human Indoleamine 2,3-Dioxygenase to be published
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2G1G
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4UM4
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4U4S
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![BU of 4u4s by Molmil](/molmil-images/mine/4u4s) | Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and BPAM25 at 1.90 A resolution. | 分子名称: | 4-ethyl-3,4-dihydro-2H-pyrido[4,3-e][1,2,4]thiadiazine 1,1-dioxide, ACETATE ION, CHLORIDE ION, ... | 著者 | Noerholm, A.B, Deva, T, Frydenvang, K, Kastrup, J.S. | 登録日 | 2014-07-24 | 公開日 | 2014-11-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides. J.Med.Chem., 57, 2014
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4U4X
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![BU of 4u4x by Molmil](/molmil-images/mine/4u4x) | Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and BPAM37 at 1.56 A resolution. | 分子名称: | 4-ethyl-3,4-dihydro-2H-pyrido[3,2-e][1,2,4]thiadiazine 1,1-dioxide, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Noerholm, A.B, Frydenvang, K, Kastrup, J.S. | 登録日 | 2014-07-24 | 公開日 | 2014-11-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides. J.Med.Chem., 57, 2014
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5K8H
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5L82
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4TUE
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4TX4
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![BU of 4tx4 by Molmil](/molmil-images/mine/4tx4) | Crystal Structure of a Single-Domain Cysteine Protease Inhibitor from Cowpea (Vigna unguiculata) | 分子名称: | Cysteine proteinase inhibitor, SULFATE ION | 著者 | Pereira, H.M, Valadares, N, Monteiro-Junior, J.E, Carvalho, C.P.S, Grangeiro, T.B. | 登録日 | 2014-07-02 | 公開日 | 2015-10-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Expression in Escherichia coli of cysteine protease inhibitors from cowpea (Vigna unguiculata): The crystal structure of a single-domain cystatin gives insights on its thermal and pH stability. Int. J. Biol. Macromol., 102, 2017
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4U21
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![BU of 4u21 by Molmil](/molmil-images/mine/4u21) | GluA2flip sLBD complexed with FW and (R,R)-2b crystal form E | 分子名称: | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide | 著者 | Chen, L, Gouaux, E. | 登録日 | 2014-07-16 | 公開日 | 2014-08-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.3908 Å) | 主引用文献 | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States. Cell, 158, 2014
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4U32
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![BU of 4u32 by Molmil](/molmil-images/mine/4u32) | Human mesotrypsin complexed with HAI-2 Kunitz domain 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Kunitz-type protease inhibitor 2, ... | 著者 | Wang, R, Soares, A.S, Radisky, E.S. | 登録日 | 2014-07-18 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Sequence and Conformational Specificity in Substrate Recognition: SEVERAL HUMAN KUNITZ PROTEASE INHIBITOR DOMAINS ARE SPECIFIC SUBSTRATES OF MESOTRYPSIN. J.Biol.Chem., 289, 2014
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