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5K9T
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SecA-N68, a C-terminal truncation of the SecA ATPase from E. coli
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translocase subunit SecA
著者Shilton, B.H, Vezina, G.C.
登録日2016-06-01
公開日2017-06-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An alternate mode of oligomerization for E. coli SecA.
Sci Rep, 7, 2017
8DXR
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BU of 8dxr by Molmil
Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 5
分子名称: Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A
著者Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E.
登録日2022-08-02
公開日2023-03-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly.
Elife, 12, 2023
8DXO
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BU of 8dxo by Molmil
Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 2
分子名称: Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A
著者Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E.
登録日2022-08-02
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly.
Elife, 12, 2023
8DXP
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BU of 8dxp by Molmil
Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 3
分子名称: Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A
著者Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E.
登録日2022-08-02
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly.
Elife, 12, 2023
8DXQ
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BU of 8dxq by Molmil
Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 4
分子名称: Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A
著者Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E.
登録日2022-08-02
公開日2023-03-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly.
Elife, 12, 2023
8DXN
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BU of 8dxn by Molmil
Structure of LRRC8C-LRRC8A(IL125) Chimera, Class 1
分子名称: Volume-regulated anion channel subunit LRRC8C,Volume-regulated anion channel subunit LRRC8A
著者Takahashi, H, Yamada, T, Denton, J.S, Strange, K, Karakas, E.
登録日2022-08-02
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly.
Elife, 12, 2023
2YSU
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BU of 2ysu by Molmil
Structure of the complex between BtuB and Colicin E2 receptor binding domain
分子名称: Colicin-E2, Vitamin B12 transporter btuB
著者Cramer, W.A, Sharma, O, Yamashita, E.
登録日2007-04-04
公開日2007-06-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the complex of the colicin E2 R-domain and its BtuB receptor. The outer membrane colicin translocon
J.Biol.Chem., 282, 2007
4U72
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BU of 4u72 by Molmil
Crystal structure of 4-phenylimidazole bound form of human indoleamine 2,3-dioxygenase (A260G mutant)
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 4-PHENYL-1H-IMIDAZOLE, Indoleamine 2,3-dioxygenase 1, ...
著者Sugimoto, H, Horitani, M, Kometani, E, Shiro, Y.
登録日2014-07-30
公開日2015-09-02
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformation and Mobility of Active Site Loop is Critical for Substrate Binding and Inhibition in Human Indoleamine 2,3-Dioxygenase
to be published
4UHJ
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BU of 4uhj by Molmil
Crystal structure of the receiver domain of CpxR from E. coli (orthorhombic form)
分子名称: MAGNESIUM ION, TRANSCRIPTIONAL REGULATORY PROTEIN CPXR
著者Mechaly, A.E, Alzari, P.M.A.
登録日2015-03-24
公開日2016-04-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase.
Structure, 25, 2017
4UHS
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BU of 4uhs by Molmil
Crystal structure of the receiver domain of CpxR from E. coli (tetragonal form)
分子名称: MAGNESIUM ION, TRANSCRIPTIONAL REGULATORY PROTEIN CPXR
著者Mechaly, A.E, Alzari, P.M.A.
登録日2015-03-25
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献Conformational plasticity of the response regulator CpxR, a key player in Gammaproteobacteria virulence and drug-resistance.
J. Struct. Biol., 204, 2018
4UHK
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BU of 4uhk by Molmil
Crystal structure of the receiver domain of CpxR from E. coli (phosphorylated)
分子名称: MAGNESIUM ION, TRANSCRIPTIONAL REGULATORY PROTEIN CPXR
著者Mechaly, A.E, Alzari, P.M.A.
登録日2015-03-24
公開日2016-04-13
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase.
Structure, 25, 2017
4UF0
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BU of 4uf0 by Molmil
Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid.
分子名称: 1,2-ETHANEDIOL, 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid, FE (II) ION, ...
著者Srikannathasan, V, Johansson, C, Gileadi, C, Tobias, K, Kopec, J, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.
登録日2014-12-22
公開日2015-01-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.
Nat.Chem.Biol., 12, 2016
4UHT
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BU of 4uht by Molmil
Crystal structure of the DNA binding domain of CpxR from E. coli
分子名称: CHLORIDE ION, TRANSCRIPTIONAL REGULATORY PROTEIN CPXR
著者Mechaly, A.E, Alzari, P.M.A.
登録日2015-03-25
公開日2016-04-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Conformational plasticity of the response regulator CpxR, a key player in Gammaproteobacteria virulence and drug-resistance.
J. Struct. Biol., 204, 2018
4V48
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BU of 4v48 by Molmil
Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the initiation-like state of E. coli 70S ribosome
分子名称: 16S RIBOSOMAL RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Gao, H, Sengupta, J, Valle, M, Korostelev, A, Eswar, N, Stagg, S.M, Van Roey, P, Agrawal, R.K, Harvey, S.T, Sali, A, Chapman, M.S, Frank, J.
登録日2003-05-06
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (11.5 Å)
主引用文献Study of the structural dynamics of the E. coli 70S ribosome using real space refinement
Cell(Cambridge,Mass.), 113, 2003
4U74
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BU of 4u74 by Molmil
Crystal structure of 4-phenylimidazole bound form of human indoleamine 2,3-dioxygenase (G262A mutant)
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 4-PHENYL-1H-IMIDAZOLE, Indoleamine 2,3-dioxygenase 1, ...
著者Sugimoto, H, Horitani, M, Kometani, E, Shiro, Y.
登録日2014-07-30
公開日2015-09-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Conformation and Mobility of Active Site Loop is Critical for Substrate Binding and Inhibition in Human Indoleamine 2,3-Dioxygenase
to be published
2G1G
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BU of 2g1g by Molmil
Solution structure of the anticodon loop of S. Pombe tRNAi including the naturally occurring N6-threonyl adenine
分子名称: 5'-R(*AP*CP*GP*GP*GP*CP*UP*CP*AP*UP*(T6A)P*AP*CP*CP*CP*GP*U)-3'
著者Lescrinier, E.
登録日2006-02-14
公開日2006-06-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif
Nucleic Acids Res., 34, 2006
4UM4
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BU of 4um4 by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM ESCHERICHIA COLI IN COMPLEX WITH SULFATE
分子名称: INORGANIC PYROPHOSPHATASE, SULFATE ION
著者Campos-Acevedo, A.A, Rudino-Pinera, E.
登録日2014-05-15
公開日2014-11-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献First attempts to crystallize a non-homogeneous sample of thioredoxin from Litopenaeus vannamei: What to do when you have diffraction data of a protein that is not the target?
Biochem Biophys Rep, 8, 2016
4U4S
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BU of 4u4s by Molmil
Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and BPAM25 at 1.90 A resolution.
分子名称: 4-ethyl-3,4-dihydro-2H-pyrido[4,3-e][1,2,4]thiadiazine 1,1-dioxide, ACETATE ION, CHLORIDE ION, ...
著者Noerholm, A.B, Deva, T, Frydenvang, K, Kastrup, J.S.
登録日2014-07-24
公開日2014-11-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides.
J.Med.Chem., 57, 2014
4U4X
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BU of 4u4x by Molmil
Crystal structure of the GluA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and BPAM37 at 1.56 A resolution.
分子名称: 4-ethyl-3,4-dihydro-2H-pyrido[3,2-e][1,2,4]thiadiazine 1,1-dioxide, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Noerholm, A.B, Frydenvang, K, Kastrup, J.S.
登録日2014-07-24
公開日2014-11-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides.
J.Med.Chem., 57, 2014
5K8H
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BU of 5k8h by Molmil
The X-ray crystal structure of a parallel poly(rA) double helix generated by rA7 at acidic pH
分子名称: AMMONIUM ION, RNA 7-mer
著者Gleghorn, M.L, Maquat, L.E.
登録日2016-05-30
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.069 Å)
主引用文献Crystal structure of a poly(rA) staggered zipper at acidic pH: evidence that adenine N1 protonation mediates parallel double helix formation.
Nucleic Acids Res., 44, 2016
5L82
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BU of 5l82 by Molmil
NMR Structure of Enterocin K1 in 50%/50% TFE/Water
分子名称: Enterococcin K1
著者Ovchinnikov, K, Kristiansen, P.E, Diep, D.
登録日2016-06-06
公開日2017-05-17
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The Leaderless Bacteriocin Enterocin K1 Is Highly Potent against Enterococcus faecium: A Study on Structure, Target Spectrum and Receptor.
Front Microbiol, 8, 2017
4TUE
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BU of 4tue by Molmil
Crystal structure of ASL-SufJ bound to Codon ACC-U on the Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fagan, C.E, Dunham, C.M.
登録日2014-06-24
公開日2015-05-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural insights into translational recoding by frameshift suppressor tRNASufJ.
Rna, 20, 2014
4TX4
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BU of 4tx4 by Molmil
Crystal Structure of a Single-Domain Cysteine Protease Inhibitor from Cowpea (Vigna unguiculata)
分子名称: Cysteine proteinase inhibitor, SULFATE ION
著者Pereira, H.M, Valadares, N, Monteiro-Junior, J.E, Carvalho, C.P.S, Grangeiro, T.B.
登録日2014-07-02
公開日2015-10-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Expression in Escherichia coli of cysteine protease inhibitors from cowpea (Vigna unguiculata): The crystal structure of a single-domain cystatin gives insights on its thermal and pH stability.
Int. J. Biol. Macromol., 102, 2017
4U21
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BU of 4u21 by Molmil
GluA2flip sLBD complexed with FW and (R,R)-2b crystal form E
分子名称: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide
著者Chen, L, Gouaux, E.
登録日2014-07-16
公開日2014-08-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.3908 Å)
主引用文献Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
4U32
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Human mesotrypsin complexed with HAI-2 Kunitz domain 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Kunitz-type protease inhibitor 2, ...
著者Wang, R, Soares, A.S, Radisky, E.S.
登録日2014-07-18
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Sequence and Conformational Specificity in Substrate Recognition: SEVERAL HUMAN KUNITZ PROTEASE INHIBITOR DOMAINS ARE SPECIFIC SUBSTRATES OF MESOTRYPSIN.
J.Biol.Chem., 289, 2014

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