4U72
Crystal structure of 4-phenylimidazole bound form of human indoleamine 2,3-dioxygenase (A260G mutant)
Summary for 4U72
Entry DOI | 10.2210/pdb4u72/pdb |
Related | 2D0T |
Descriptor | Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, 4-PHENYL-1H-IMIDAZOLE, ... (5 entities in total) |
Functional Keywords | metal-binding, all alpha, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 93655.39 |
Authors | Sugimoto, H.,Horitani, M.,Kometani, E.,Shiro, Y. (deposition date: 2014-07-30, release date: 2015-09-02, Last modification date: 2020-01-29) |
Primary citation | Horitani, M.,Kometani, E.,Vottero, E.,Otsuki, T.,Shiro, Y.,Sugimoto, H. Conformation and Mobility of Active Site Loop is Critical for Substrate Binding and Inhibition in Human Indoleamine 2,3-Dioxygenase to be published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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