7ACL
 
 | |
7ACM
 | |
6SCH
 | | NADH-dependent variant of CBADH | | 分子名称: | MAGNESIUM ION, NADP-dependent isopropanol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Selles Vidal, L, Murray, J.W, Heap, J.T. | | 登録日 | 2019-07-24 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Versatile selective evolutionary pressure using synthetic defect in universal metabolism.
Nat Commun, 12, 2021
|
|
7ATJ
 | | RECOMBINANT HORSERADISH PEROXIDASE C1A COMPLEX WITH CYANIDE AND FERULIC ACID | | 分子名称: | 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, CALCIUM ION, CYANIDE ION, ... | | 著者 | Henriksen, A, Smith, A.T, Gajhede, M. | | 登録日 | 1999-04-26 | | 公開日 | 2000-01-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | The structures of the horseradish peroxidase C-ferulic acid complex and the ternary complex with cyanide suggest how peroxidases oxidize small phenolic substrates.
J.Biol.Chem., 274, 1999
|
|
7K4H
 | | Human Arginase 1 in complex with compound 04. | | 分子名称: | 3-[(1~{R},5~{S},8~{R})-5-carboxy-2,6-diazabicyclo[3.2.1]octan-8-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION | | 著者 | Palte, R.L. | | 登録日 | 2020-09-15 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
|
|
7K4J
 | | Human Arginase 1 in complex with compound 51. | | 分子名称: | 3-[(1~{S},2~{S},5~{R})-2-carboxy-3,6-diazabicyclo[3.2.0]heptan-1-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION | | 著者 | Palte, R.L. | | 登録日 | 2020-09-15 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
|
|
7VMD
 | | Crystal structure of a hydrolases Ple628 from marine microbial consortium | | 分子名称: | CALCIUM ION, hydrolase Ple628 | | 著者 | Wu, P, Zhao, Y.P, Li, Z.S, Ingrid, M.C, Lara, P, Gao, J, Han, X, Li, Q, Basak, O, Liu, W.D, Wei, R. | | 登録日 | 2021-10-08 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Molecular and Biochemical Differences of the Tandem and Cold-Adapted PET Hydrolases Ple628 and Ple629, Isolated From a Marine Microbial Consortium.
Front Bioeng Biotechnol, 10, 2022
|
|
7K4G
 | | Human Arginase 1 in complex with compound 01. | | 分子名称: | 3-[(2~{S},3~{R})-2-carboxypyrrolidin-3-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION | | 著者 | Palte, R.L. | | 登録日 | 2020-09-15 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
|
|
4XN6
 | | Crystal structure at room temperature of hen-egg lysozyme in complex with benzamidine | | 分子名称: | BENZAMIDINE, Lysozyme C | | 著者 | Gelin, M, Allemand, F, Labesse, G, Guichou, J.F. | | 登録日 | 2015-01-15 | | 公開日 | 2015-08-12 | | 最終更新日 | 2021-08-04 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography.
Acta Crystallogr.,Sect.D, 71, 2015
|
|
7K4K
 | | Human Arginase 1 in complex with compound 52. | | 分子名称: | 3-[(3~{a}~{S},4~{S},6~{a}~{R})-4-carboxy-2,3,4,5,6,6~{a}-hexahydro-1~{H}-pyrrolo[2,3-c]pyrrol-3~{a}-yl]propyl-$l^{3}-oxidanyl-bis(oxidanyl)boranuide, Arginase-1, MANGANESE (II) ION | | 著者 | Palte, R.L. | | 登録日 | 2020-09-15 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
|
|
7AH1
 | | L19 diabody fragment from immunocytokine L19-IL2 | | 分子名称: | Anti-(ED-B) scFV | | 著者 | Ongaro, T, Guarino, S.R, Scietti, L, Palamini, M, Wulhfard, S, Villa, A, Neri, D, Forneris, F. | | 登録日 | 2020-09-23 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Inference of molecular structure for characterization and improvement of clinical grade immunocytokines.
J.Struct.Biol., 213, 2021
|
|
4XDO
 | |
6SJV
 | | Structure of HPV18 E6 oncoprotein in complex with mutant E6AP LxxLL motif | | 分子名称: | Maltodextrin-binding protein,Protein E6,Ubiquitin-protein ligase E3A, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Suarez, I.P, Cousido-Siah, A, Bonhoure, A, Kostmann, C, Mitschler, A, Podjarny, A, Trave, G. | | 登録日 | 2019-08-14 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.029 Å) | | 主引用文献 | Cellular target recognition by HPV18 and HPV49 oncoproteins
To be published
|
|
5EXP
 | | AAA+ domain of FleQ from Pseudomonas aeruginosa | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Transcriptional regulator FleQ | | 著者 | Navarro, M.V.A.S, Sondermann, H, Matsuyama, B.Y. | | 登録日 | 2015-11-24 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanistic insights into c-di-GMP-dependent control of the biofilm regulator FleQ from Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
6SO2
 | | Fragment N13460a in complex with MAP kinase p38-alpha | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Mitogen-activated protein kinase 14, ... | | 著者 | Nichols, C.E, De Nicola, G.F. | | 登録日 | 2019-08-28 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes.
J.Med.Chem., 63, 2020
|
|
6SPL
 | | Fragment KCL615 in complex with MAP kinase p38-alpha | | 分子名称: | (5~{S},7~{R})-3-azanyladamantan-1-ol, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, CALCIUM ION, ... | | 著者 | Nichols, C.E, De Nicola, G.F. | | 登録日 | 2019-09-01 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes.
J.Med.Chem., 63, 2020
|
|
5LC7
 | |
7AOE
 | | Schizosaccharomyces pombe RNA polymerase I (elongation complex) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit rpa1, DNA-directed RNA polymerase I subunit rpa14, ... | | 著者 | Heiss, F, Daiss, J, Becker, P, Engel, C. | | 登録日 | 2020-10-14 | | 公開日 | 2021-02-24 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Conserved strategies of RNA polymerase I hibernation and activation.
Nat Commun, 12, 2021
|
|
7ATF
 | | Structure of EstD11 in complex with p-Nitrophenol | | 分子名称: | ACETATE ION, EstD11, FORMIC ACID, ... | | 著者 | Miguel-Ruano, V, Rivera, I, Hermoso, J.A. | | 登録日 | 2020-10-30 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Biochemical and Structural Characterization of a novel thermophilic esterase EstD11 provide catalytic insights for the HSL family.
Comput Struct Biotechnol J, 19, 2021
|
|
7AOC
 | | Schizosaccharomyces pombe RNA polymerase I (monomer) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit rpa1, DNA-directed RNA polymerase I subunit rpa14, ... | | 著者 | Heiss, F, Daiss, J, Becker, P, Engel, C. | | 登録日 | 2020-10-14 | | 公開日 | 2021-02-24 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Conserved strategies of RNA polymerase I hibernation and activation.
Nat Commun, 12, 2021
|
|
7AV5
 | | Structure of EstD11 in complex with Fluorescein | | 分子名称: | ACETATE ION, EstD11, FLUORESCIN, ... | | 著者 | Miguel-Ruano, V, Rivera, I, Hermoso, J.A. | | 登録日 | 2020-11-04 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Biochemical and Structural Characterization of a novel thermophilic esterase EstD11 provide catalytic insights for the HSL family.
Comput Struct Biotechnol J, 19, 2021
|
|
7AOD
 | | Schizosaccharomyces pombe RNA polymerase I (dimer) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit rpa1, DNA-directed RNA polymerase I subunit rpa14, ... | | 著者 | Heiss, F, Daiss, J, Becker, P, Engel, C. | | 登録日 | 2020-10-14 | | 公開日 | 2021-02-24 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Conserved strategies of RNA polymerase I hibernation and activation.
Nat Commun, 12, 2021
|
|
7AT0
 | |
2WNL
 | | CRYSTAL STRUCTURE OF APLYSIA ACHBP IN COMPLEX WITH ANABASEINE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4,5,6-tetrahydro-2,3'-bipyridine, 5-amino-1-pyridin-3-ylpentan-1-one, ... | | 著者 | Sulzenbacher, G, Hibbs, R, Shi, J, Talley, T, Conrod, S, Kem, W, Taylor, P, Marchot, P, Bourne, Y. | | 登録日 | 2009-07-09 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
EMBO J., 28, 2009
|
|
5F46
 | | Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample, apoenzyme form | | 分子名称: | CHLORIDE ION, aminoglycoside acetyltransferase meta-AAC0020 | | 著者 | Xu, Z, Skarina, T, Stogios, P.J, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2015-12-03 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes.
ACS Infect Dis, 3, 2017
|
|
