2FPS
 
 | | Crystal structure of the N-terminal domain of E.coli HisB- Apo Ca model. | | 分子名称: | CALCIUM ION, CHLORIDE ION, Histidine biosynthesis bifunctional protein hisB, ... | | 著者 | Rangarajan, E.S, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2006-01-17 | | 公開日 | 2006-09-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway.
J.Biol.Chem., 281, 2006
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3GVK
 | | Crystal structure of endo-neuraminidase NF mutant | | 分子名称: | Endo-N-acetylneuraminidase, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid, ... | | 著者 | Schulz, E.C, Dickmanns, A, Ficner, R. | | 登録日 | 2009-03-31 | | 公開日 | 2010-03-02 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural basis for the recognition and cleavage of polysialic acid by the bacteriophage K1F tailspike protein EndoNF.
J.Mol.Biol., 397, 2010
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2FPR
 | | Crystal structure the N-terminal domain of E. coli HisB. Apo Mg model. | | 分子名称: | BROMIDE ION, Histidine biosynthesis bifunctional protein hisB, MAGNESIUM ION, ... | | 著者 | Rangarajan, E.S, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2006-01-17 | | 公開日 | 2006-09-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway.
J.Biol.Chem., 281, 2006
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2G9Y
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3HFN
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2GA3
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6KML
 | | 2.09 Angstrom resolution crystal structure of tetrameric HigBA toxin-antitoxin complex from E.coli | | 分子名称: | Antitoxin HigA, mRNA interferase toxin HigB | | 著者 | Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M. | | 登録日 | 2019-07-31 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | | 主引用文献 | 2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.
Biochem.J., 477, 2020
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8EA5
 | | NKG2D complexed with inhibitor 1a | | 分子名称: | (3S,5aS,8aR)-3-benzyl-6-[(3,5-dichlorophenyl)methyl]-1,4-dimethyloctahydropyrrolo[3,2-e][1,4]diazepine-2,5-dione, NKG2-D type II integral membrane protein, TRIETHYLENE GLYCOL | | 著者 | Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S. | | 登録日 | 2022-08-28 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-05-10 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8E1O
 | | Crystal structure of hTEAD2 bound to a methoxypyridine lipid pocket binder | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-methoxy-N-({3-[2-(methylamino)-2-oxoethyl]phenyl}methyl)-4-{(E)-2-[trans-4-(trifluoromethyl)cyclohexyl]ethenyl}pyridine-2-carboxamide, Transcriptional enhancer factor TEF-4 | | 著者 | Noland, C.L, Dey, A, Zbieg, J, Crawford, J. | | 登録日 | 2022-08-10 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
Biorxiv, 2024
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2FQ1
 | | Crystal structure of the two-domain non-ribosomal peptide synthetase EntB containing isochorismate lyase and aryl-carrier protein domains | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Isochorismatase, ... | | 著者 | Drake, E.J, Nicolai, D.A, Gulick, A.M. | | 登録日 | 2006-01-17 | | 公開日 | 2006-05-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain.
Chem.Biol., 13, 2006
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2FQT
 | | Crystal structure of B.subtilis LuxS in complex with (2S)-2-Amino-4-[(2R,3S)-2,3-dihydroxy-3-N-hydroxycarbamoyl-propylmercapto]butyric acid | | 分子名称: | (2S)-2-AMINO-4-[(2R,3S)-2,3-DIHYDROXY-3-N-HYDROXYCARBAMOYL-PROPYLMERCAPTO]BUTYRIC ACID, COBALT (II) ION, S-ribosylhomocysteine lyase, ... | | 著者 | Shen, G, Rajan, R, Zhu, J, Bell, C.E, Pei, D. | | 登録日 | 2006-01-18 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Design and Synthesis of Substrate Analogue Inhibitors of S-Ribosylhomocysteinase (LuxS)
J.Med.Chem., 49, 2006
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8EE5
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5L7K
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8E9W
 | | CryoEM structure of miniGq-coupled hM3Dq in complex with DCZ | | 分子名称: | 11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhang, S, Fay, J.F, Roth, B.L. | | 登録日 | 2022-08-27 | | 公開日 | 2022-11-30 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | | 主引用文献 | Molecular basis for selective activation of DREADD-based chemogenetics.
Nature, 612, 2022
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8E9X
 | | CryoEM structure of miniGo-coupled hM4Di in complex with DCZ | | 分子名称: | 11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhang, S, Fay, J.F, Roth, B.L. | | 登録日 | 2022-08-27 | | 公開日 | 2022-11-30 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Molecular basis for selective activation of DREADD-based chemogenetics.
Nature, 612, 2022
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8E9Y
 | | CryoEM structure of miniGq-coupled hM3Dq in complex with CNO | | 分子名称: | 8-chloro-11-(4-methyl-4-oxo-4lambda~5~-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhang, S, Fay, J.F, Roth, B.L. | | 登録日 | 2022-08-27 | | 公開日 | 2022-11-30 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | | 主引用文献 | Molecular basis for selective activation of DREADD-based chemogenetics.
Nature, 612, 2022
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4FKM
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2FVN
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5K33
 | | Crystal structure of extracellular domain of HER2 in complex with Fcab STAB19 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ig gamma-1 chain C region, ... | | 著者 | Humm, A, Lobner, E, Goritzer, K, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | | 登録日 | 2016-05-19 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies.
Structure, 25, 2017
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2FX3
 | | Crystal Structure Determination of E. coli Elongation Factor, Tu using a Twinned Data Set | | 分子名称: | Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Heffron, S.E, Moeller, R, Jurnak, F. | | 登録日 | 2006-02-03 | | 公開日 | 2006-03-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Solving the structure of Escherichia coli elongation factor Tu using a twinned data set.
Acta Crystallogr.,Sect.D, 62, 2006
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6KMQ
 | | 2.3 Angstrom resolution structure of dimeric HigBA toxin-antitoxin complex from E. coli | | 分子名称: | Antitoxin HigA, mRNA interferase toxin HigB | | 著者 | Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M. | | 登録日 | 2019-07-31 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | 2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.
Biochem.J., 477, 2020
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4U3G
 | | Crystal structure of Escherichia coli bacterioferritin mutant D132F | | 分子名称: | Bacterioferritin, SULFATE ION | | 著者 | Wong, S.G, Grigg, J.C, Le Brun, N.E, Moore, G.R, Murphy, M.E.P, Mauk, A.G. | | 登録日 | 2014-07-21 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The B-type Channel Is a Major Route for Iron Entry into the Ferroxidase Center and Central Cavity of Bacterioferritin.
J.Biol.Chem., 290, 2015
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4UT6
 | | Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 B7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7, ... | | 著者 | Rouvinski, A, Guardado-Calvo, P, Barba-Spaeth, G, Duquerroy, S, Vaney, M.C, Rey, F.A. | | 登録日 | 2014-07-18 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
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4UTA
 | | Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C8 | | 分子名称: | BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 HEAVY CHAIN, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 LIGHT CHAIN, ENVELOPE GLYCOPROTEIN E, ... | | 著者 | Rouvinski, A, Guardado-Calvo, P, Barba-Spaeth, G, Duquerroy, S, Vaney, M.C, Rey, F.A. | | 登録日 | 2014-07-18 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
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7LNA
 | | Infectious mammalian prion fibril (263K scrapie) | | 分子名称: | Major prion protein | | 著者 | Kraus, A, Hoyt, F, Schwartz, C.L, Hansen, B, Hughson, A.G, Artikis, E, Race, B, Caughey, B. | | 登録日 | 2021-02-06 | | 公開日 | 2021-09-01 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | High-resolution structure and strain comparison of infectious mammalian prions.
Mol.Cell, 81, 2021
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