7K6Q
| Active state Dot1 bound to the H4K16ac nucleosome | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J. | 登録日 | 2020-09-21 | 公開日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation. Science, 371, 2021
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5MLU
| Crystal structure of the PFV GAG CBS bound to a mononucleosome | 分子名称: | DNA (145-MER), Histone H2A type 1, Histone H2B, ... | 著者 | Pye, V.E, Maskell, D.P, Lesbats, P, Cherepanov, P. | 登録日 | 2016-12-07 | 公開日 | 2017-05-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for spumavirus GAG tethering to chromatin. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4ICG
| N-terminal dimerization domain of H-NS in complex with Hha (Salmonella Typhimurium) | 分子名称: | DNA-binding protein H-NS, Hemolysin expression modulating protein (Involved in environmental regulation of virulence factors) | 著者 | Ali, S.S, Whitney, J.C, Stevenson, J, Robinson, H, Howell, P.L, Navarre, W.W. | 登録日 | 2012-12-10 | 公開日 | 2013-03-27 | 最終更新日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (2.9217 Å) | 主引用文献 | Structural Insights into the Regulation of Foreign Genes in Salmonella by the Hha/H-NS Complex. J.Biol.Chem., 288, 2013
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8HOV
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5O4D
| G-quadruplex of Human papillomavirus type 52 | 分子名称: | DNA (5'-D(*GP*GP*GP*TP*AP*GP*GP*GP*CP*AP*GP*GP*GP*GP*AP*CP*AP*CP*AP*GP*GP*GP*T)-3') | 著者 | Marusic, M, Plavec, J. | 登録日 | 2017-05-29 | 公開日 | 2018-06-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Towards Understanding of Polymorphism of the G-rich Region of Human Papillomavirus Type 52. Molecules, 24, 2019
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3V30
| Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human RFXANK | 分子名称: | DNA-binding protein RFX5, DNA-binding protein RFXANK | 著者 | Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2011-12-12 | 公開日 | 2012-04-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5, 2012
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3BUA
| Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex | 分子名称: | DNA cross-link repair 1B protein, Telomeric repeat-binding factor 2 | 著者 | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | 登録日 | 2008-01-02 | 公開日 | 2008-02-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science, 319, 2008
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7K6P
| Active state Dot1 bound to the unacetylated H4 nucleosome | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J. | 登録日 | 2020-09-21 | 公開日 | 2021-02-10 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation. Science, 371, 2021
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332D
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7Z5I
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6BCH
| I-LtrI E29D bound to cognate substrate (nicked complex) | 分子名称: | DNA (26-MER), DNA (5'-D(*GP*GP*TP*CP*TP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*GP*GP*AP*GP*CP*AP*TP*TP*T)-3'), ... | 著者 | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | 登録日 | 2017-10-20 | 公開日 | 2018-10-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | I-LtrI E29D bound to cognate substrate (nicked complex) To Be Published
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6Z6P
| HDAC-PC-Nuc | 分子名称: | DNA (145-MER), HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, ... | 著者 | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | 登録日 | 2020-05-28 | 公開日 | 2021-02-17 | 実験手法 | ELECTRON MICROSCOPY (4.43 Å) | 主引用文献 | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies. Sci Adv, 7, 2021
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8YOD
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8YO5
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7Z5K
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9B0L
| Cryo-EM structure of Acanthamoeba polyphaga mimivirus Fanzor2 ternary complex | 分子名称: | DNA (5'-D(P*AP*GP*GP*AP*GP*GP*TP*GP*GP*CP*TP*GP*CP*CP*CP*CP*GP*AP*CP*CP*GP*TP*C)-3'), DNA (5'-D(P*CP*CP*CP*A)-3'), DNA (5'-D(P*GP*AP*CP*GP*GP*TP*CP*GP*GP*GP*C)-3'), ... | 著者 | Qayyum, M.Z, Schargel, R.D, Tanwar, A.S, Kellogg, E.H, Kalathur, R.C. | 登録日 | 2024-03-12 | 公開日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Structure of Fanzor2 reveals insights into the evolution of the TnpB superfamily. Nat.Struct.Mol.Biol., 2024
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8USP
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8USQ
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7BUJ
| mcGAS bound with pppGpG | 分子名称: | Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Wang, B, Su, X.D. | 登録日 | 2020-04-07 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Mn2+Directly Activates cGAS and Structural Analysis Suggests Mn2+Induces a Noncanonical Catalytic Synthesis of 2'3'-cGAMP. Cell Rep, 32, 2020
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5Z23
| Crystal structure of the nucleosome containing a chimeric histone H3/CENP-A CATD | 分子名称: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Arimura, Y, Tachiwana, H, Takagi, H. | 登録日 | 2017-12-28 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism. Nat Commun, 10, 2019
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8A39
| Crystal Structure of PaaX from Escherichia coli W | 分子名称: | DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive, GLYCEROL, ... | 著者 | Molina, R, Alba-Perez, A, Hermoso, J.A. | 登録日 | 2022-06-07 | 公開日 | 2023-07-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural characterization of PaaX, the main repressor of the phenylacetate degradation pathway in Escherichia coli W: A novel fold of transcription regulator proteins. Int.J.Biol.Macromol., 254, 2024
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8PIA
| DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>T) | 分子名称: | Chains: E, Chains: F, GLYCEROL, ... | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | 登録日 | 2023-06-21 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
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8PI8
| DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA | 分子名称: | Chains: E, Chains: F, GLYCEROL, ... | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | 登録日 | 2023-06-21 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
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8PI9
| DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>A) | 分子名称: | Chains: E, Chains: F, Hepatocyte nuclear factor 1-alpha | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | 登録日 | 2023-06-21 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
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8PI7
| DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -169C>T) | 分子名称: | CHLORIDE ION, Chains: E, Chains: F, ... | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | 登録日 | 2023-06-21 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
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