PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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1GYN	Class II fructose 1,6-bisphosphate aldolase with Cadmium (not Zinc) in the active site 分子名称: CADMIUM ION, FRUCTOSE-BISPHOSPHATE ALDOLASE II 著者 Hall, D.R, Kemp, L.E, Leonard, G.A, Berry, A, Hunter, W.N. 登録日 2002-04-27 公開日 2003-02-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Organization of Divalent Cations in the Active Site of Cadmium Escherichia Coli Fructose 1,6-Bisphosphate Aldolase Acta Crystallogr.,Sect.D, 59, 2003
1GQ4	STRUCTURAL DETERMINANTS OF THE NHERF INTERACTION WITH BETA2AR AND PDGFR 分子名称: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50 著者 Karthikeyan, S, Leung, T, Ladias, J.A.A. 登録日 2001-11-19 公開日 2002-05-21 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors J.Biol.Chem., 277, 2002
1GQM	The structure of S100A12 in a hexameric form and its proposed role in receptor signalling 分子名称: CALCIUM ION, CALGRANULIN C 著者 Moroz, O.V, Antson, A.A, Dodson, E.G, Burrel, H.J, Grist, S.J, Lloyd, R.M, Maitland, N.J, Dodson, G.G, Wilson, K.S, Lukanidin, E, Bronstein, I.B. 登録日 2001-11-26 公開日 2002-02-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Structure of S100A12 in a Hexameric Form and its Proposed Role in Receptor Signalling Acta Crystallogr.,Sect.D, 58, 2002
1GSM	A reassessment of the MAdCAM-1 structure and its role in integrin recognition. 分子名称: MUCOSAL ADDRESSIN CELL ADHESION MOLECULE-1 著者 Dando, J, Wilkinson, K.W, Ortlepp, S, King, D.J, Brady, R.L. 登録日 2002-01-08 公開日 2002-01-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Reassessment of the Madcam-1 Structure and its Role in Integrin Recognition Acta Crystallogr.,Sect.D, 58, 2002
1GTK	Time-resolved and static-ensemble structural chemistry of hydroxymethylbilane synthase 分子名称: 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, PORPHOBILINOGEN DEAMINASE 著者 Helliwell, J.R, Nieh, Y.P, Raftery, J, Cassetta, A, Habash, J, Carr, P.D, Ursby, T, Wulff, M, Thompson, A.W, Niemann, A.C, Haedener, A. 登録日 2002-01-16 公開日 2003-01-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Time-Resolved and Static-Ensemble Structural Chemistry of Hydroxymethylbilane Synthase Faraday Discuss., 122, 2003
4WVS	Crystal structure of XIAP-BIR2 domain complexed with (S)-3-(4-methoxyphenyl)-2-((S)-2-((S)-1-((S)-2-((S)-2-(methylamino)propanamido)pent-4-ynoyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)propanoic acid 分子名称: 3,11-DIFLUORO-6,8,13-TRIMETHYL-8H-QUINO[4,3,2-KL]ACRIDIN-13-IUM, E3 ubiquitin-protein ligase XIAP, GLYCEROL, ... 著者 Pokross, M.E. 登録日 2014-11-07 公開日 2015-05-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity. J.Med.Chem., 58, 2015
1GUS	MopII from Clostridium pasteurianum (apo1) 分子名称: CHLORIDE ION, MAGNESIUM ION, MOLYBDATE BINDING PROTEIN II 著者 Schuettelkopf, A.W, Harrison, J.A, Hunter, W.N. 登録日 2002-01-28 公開日 2002-02-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Passive Acquisition of Ligand by the Mopii Molbindin from Clostridium Pasteurianum: Structures of Apo and Oxyanion-Bound Forms J.Biol.Chem., 277, 2002
6YRP	Crystal Structure of the VIM-2 Acquired Metallo-beta-Lactamase in Complex with JMV-4690 (Cpd 31) 分子名称: 1,2-ETHANEDIOL, 2-[[[3-(5-methoxy-2-oxidanyl-phenyl)-5-sulfanylidene-1~{H}-1,2,4-triazol-4-yl]amino]methyl]benzoic acid, ACETATE ION, ... 著者 Docquier, J.D, Pozzi, C, De Luca, F, Benvenuti, M, Mangani, S. 登録日 2020-04-20 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 208, 2020
8FO4	Structure of full-length amyloidogenic immunoglobulin light chain H9 in complex with 6-methyl-2-(2-((1E,2E)-3-(2-nitrophenyl)allylidene)hydrazineyl)pyrimidin-4-ol 分子名称: 6-methyl-2-{2-[(1E)-3-(2-nitrophenyl)prop-1-en-1-yl]hydrazinyl}pyrimidin-4(5H)-one, H9 immunoglobulin light chain, PHOSPHATE ION 著者 Yan, N.L, Wilson, I.A, Kelly, J.W. 登録日 2022-12-29 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of Diaryl Hydrazone and Sulfone Stabilizers in Complex with an Amyloidogenic Light Chain Reveal an Alternate Ligand-Binding Cavity Isr.J.Chem., 2023
8FUJ	HIV-1 wild type protease with GRL-03419A, with N-(2,5-dimethylphenyl)-4-(pyridin-3-yl)pyrimidin-2-amine as P2-P3 group and 3,5-difluorophenylmethyl as the P1 group 分子名称: CHLORIDE ION, FORMIC ACID, GLYCEROL, ... 著者 Wang, Y.-F, Agniswamy, J, Ghosh, A.K, Weber, I.T. 登録日 2023-01-17 公開日 2023-05-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation. Eur.J.Med.Chem., 255, 2023
1GY9	Taurine/alpha-ketoglutarate Dioxygenase from Escherichia coli 分子名称: 2-AMINOETHANESULFONIC ACID, 2-OXOGLUTARIC ACID, ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE, ... 著者 Elkins, J.M, Burzlaff, N.I, Ryle, M.J, Lloyd, J.S, Clifton, I.J, Baldwin, J.E, Hausinger, R.P, Roach, P.L. 登録日 2002-04-22 公開日 2002-04-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 X-Ray Crystal Structure of Escherichia Coli Taurine/Alpha-Ketoglutarate Dioxygenase Complexed to Ferrous Iron and Substrates. Biochemistry, 41, 2002
1GZ8	HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 2-Amino-6-(3'-methyl-2'-oxo)butoxypurine 分子名称: 1-[(2-AMINO-6,9-DIHYDRO-1H-PURIN-6-YL)OXY]-3-METHYL-2-BUTANOL, CELL DIVISION PROTEIN KINASE 2 著者 Davies, T, Endicott, J, Johnson, L, Noble, M, Tucker, J. 登録日 2002-05-17 公開日 2003-06-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O(6)-Substituted Guanine Derivatives J.Med.Chem., 45, 2002
1H4D	Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis protein MobA 分子名称: CITRIC ACID, LITHIUM ION, MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A 著者 Guse, A, Stevenson, C.E.M, Kuper, J, Buchanan, G, Schwarz, G, Mendel, R.R, Lawson, D.M, Palmer, T. 登録日 2003-02-26 公開日 2003-05-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba J.Biol.Chem., 278, 2003
1H0R	Type II Dehydroquinase from Mycobacterium tuberculosis complexed with 2,3-anhydro-quinic acid 分子名称: 2,3 -ANHYDRO-QUINIC ACID, 3-DEHYDROQUINATE DEHYDRATASE, CHLORIDE ION, ... 著者 Roszak, A.W, Robinson, D.A, Frederickson, M, Abell, C, Coggins, J.R, Lapthorn, A.J. 登録日 2002-06-27 公開日 2003-10-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for Selectivity of Oxime Based Inhibitors Towards Type II Dehydroquinase from Mycobacterium Tuberculosis To be Published
2DUT	Crystal structure of a M-loop deletion variant of MENT in the native conformation 分子名称: Heterochromatin-associated protein MENT 著者 Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A. 登録日 2006-07-26 公開日 2006-08-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation Embo J., 25, 2006
8FIV	Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor Jun10541R 分子名称: (3Z)-N-([1,1'-biphenyl]-4-yl)-3-imino-N-[(1R)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]propanamide, 3C-like proteinase nsp5 著者 Sacco, M, Wang, J, Chen, Y. 登録日 2022-12-16 公開日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Exploring diverse reactive warheads for the design of SARS-CoV-2 main protease inhibitors. Eur.J.Med.Chem., 259, 2023
6YRW	SHMT from Streptococcus thermophilus Tyr55Ser variant as internal aldimine and as non-covalent complex with D-Ser 分子名称: D-SERINE, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Petrillo, G, Hernandez, K, Bujons, J, Clapes, P, Uson, I. 登録日 2020-04-20 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insights into nucleophile substrate specificity in variants of N-Serine hydroxymethyltransferase from Streptococcus thermophilus To Be Published
1H0K	Enoyl thioester reductase 2 分子名称: 2,4-DIENOYL-COA REDUCTASE, GLYCEROL, SULFATE ION 著者 Airenne, T.T, Torkko, J.M, Hiltunen, J.K. 登録日 2002-06-20 公開日 2003-06-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystal Structure of Enoyl Thioester Reductase 2 To be Published
1H0H	Tungsten containing Formate Dehydrogenase from Desulfovibrio Gigas 分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Raaijmakers, H.C.A. 登録日 2002-06-19 公開日 2003-02-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Gene Sequence and the 1.8 A Crystal Structure of the Tungsten-Containing Formate Dehydrogenase from Desulfovibrio Gigas Structure, 10, 2002
8FIW	Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor Jun10221 分子名称: 3C-like proteinase nsp5, N-([1,1'-biphenyl]-4-yl)-N-[(1R)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]prop-2-enamide, N-([1,1'-biphenyl]-4-yl)-N-[(1S)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]prop-2-enamide 著者 Sacco, M, Wang, J, Chen, Y. 登録日 2022-12-16 公開日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Exploring diverse reactive warheads for the design of SARS-CoV-2 main protease inhibitors. Eur.J.Med.Chem., 259, 2023
1GXD	proMMP-2/TIMP-2 complex 分子名称: 72 KDA TYPE IV COLLAGENASE, CALCIUM ION, METALLOPROTEINASE INHIBITOR 2, ... 著者 Morgunova, E, Tuuttila, A, Bergmann, U, Tryggvason, K. 登録日 2002-04-02 公開日 2002-07-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Insight Into the Complex Formation of Latent Matrix Metalloproteinase 2 with Tissue Inhibitor of Metalloproteinase 2 Proc.Natl.Acad.Sci.USA, 99, 2002
1HD5	Endoglucanase from Humicola insolens AT 1.7A resolution 分子名称: ENDOGLUCANASE 著者 McAuley, K.E, Wilson, K.S, Schulein, M. 登録日 2000-11-08 公開日 2000-12-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Endoglucanase from Humicola Insolens at 1.7A Resolution To be Published
2DGN	Mouse Muscle Adenylosuccinate Synthetase partially ligated complex with GTP, 2'-deoxy-IMP 分子名称: 9-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-6-(PHOSPHONOOXY)-9H-PURINE, Adenylosuccinate synthetase isozyme 1, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Iancu, C.V, Zhou, Y, Borza, T, Fromm, H.J, Honzatko, R.B. 登録日 2006-03-15 公開日 2006-09-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases. Biochemistry, 45, 2006
1H7A	Structural basis for allosteric substrate specificity regulation in class III ribonucleotide reductases: NRDD in complex with dATP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN, FE (II) ION, ... 著者 Larsson, K.-M, Andersson, J, Sjoeberg, B.-M, Nordlund, P, Logan, D.T. 登録日 2001-07-04 公開日 2002-03-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase Structure, 9, 2001
1GX5	Hepatitis C Virus RNA Polymerase in Complex with GTP and Manganese 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Bressanelli, S, Rey, F.A. 登録日 2002-03-27 公開日 2002-04-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides J.Virol., 76, 2002

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