1A0K
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6ZQF
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![BU of 6zqf by Molmil](/molmil-images/mine/6zqf) | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-B (Poly-Ala) | 分子名称: | 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... | 著者 | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2020-07-09 | 公開日 | 2020-09-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
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6W08
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![BU of 6w08 by Molmil](/molmil-images/mine/6w08) | Crystal Structure of Motility Associated Killing Factor E from Vibrio cholerae | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | 著者 | Kim, Y, Jedrzejczak, R, Joachimiak, G, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-02-29 | 公開日 | 2020-03-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins. J.Bacteriol., 204, 2022
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3BZ3
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2C3O
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![BU of 2c3o by Molmil](/molmil-images/mine/2c3o) | CRYSTAL STRUCTURE OF THE FREE RADICAL INTERMEDIATE OF PYRUVATE:FERREDOXIN OXIDOREDUCTASE FROM Desulfovibrio africanus | 分子名称: | CALCIUM ION, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | 著者 | Cavazza, C, Contreras-Martel, C, Pieulle, L, Chabriere, E, Hatchikian, E.C, Fontecilla-Camps, J.C. | 登録日 | 2005-10-11 | 公開日 | 2006-02-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Flexibility of Thiamine Diphosphate Revealed by Kinetic Crystallographic Studies of the Reaction of Pyruvate-Ferredoxin Oxidoreductase with Pyruvate. Structure, 14, 2006
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8VZP
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![BU of 8vzp by Molmil](/molmil-images/mine/8vzp) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-403 | 分子名称: | (1S,2R,4S)-N-(2-hydroxyethyl)-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-12 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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5IQQ
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2C3U
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![BU of 2c3u by Molmil](/molmil-images/mine/2c3u) | Crystal Structure Of Pyruvate-Ferredoxin Oxidoreductase From Desulfovibrio africanus, Oxygen inhibited form | 分子名称: | 2-(3-{[4-(HYDROXYAMINO)-2-METHYLPYRIMIDIN-5-YL]METHYL}-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL)ETHYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, IRON/SULFUR CLUSTER, ... | 著者 | Cavazza, C, Contreras-Martel, C, Pieulle, L, Chabriere, E, Hatchikian, E.C, Fontecilla-Camps, J.C. | 登録日 | 2005-10-12 | 公開日 | 2006-02-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Flexibility of Thiamine Diphosphate Revealed by Kinetic Crystallographic Studies of the Reaction of Pyruvate-Ferredoxin Oxidoreductase with Pyruvate. Structure, 14, 2006
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8VYT
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![BU of 8vyt by Molmil](/molmil-images/mine/8vyt) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-411 | 分子名称: | 4,4'-[(1R,4R,5S)-5-(2,3-dihydro-1H-indole-1-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-09 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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2C42
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![BU of 2c42 by Molmil](/molmil-images/mine/2c42) | Crystal Structure Of Pyruvate-Ferredoxin Oxidoreductase From Desulfovibrio africanus | 分子名称: | CALCIUM ION, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | 著者 | Cavazza, C, Contreras-Martel, C, Pieulle, L, Chabriere, E, Hatchikian, E.C, Fontecilla-Camps, J.C. | 登録日 | 2005-10-14 | 公開日 | 2006-12-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Flexibility of Thiamine Diphosphate Revealed by Kinetic Crystallographic Studies of the Reaction of Pyruvate-Ferredoxin Oxidoreductase with Pyruvate. Structure, 14, 2006
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8VZ1
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![BU of 8vz1 by Molmil](/molmil-images/mine/8vz1) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-409 | 分子名称: | 4,4'-[(1S,4S,5R)-5-(6-methoxy-3,4-dihydroquinoline-1(2H)-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-09 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VJ6
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![BU of 8vj6 by Molmil](/molmil-images/mine/8vj6) | GluA2 bound to GYKI-52466 and Glutamate, Inhibited State 1 | 分子名称: | 4-[(5S,8R)-8-methyl-6,7,8,9-tetrahydro-2H,5H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl]aniline, Isoform Flip of Glutamate receptor 2 | 著者 | Hale, W.D, Montano Romero, A, Huganir, R.L, Twomey, E.C. | 登録日 | 2024-01-05 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Allosteric competition and inhibition in AMPA receptors. Nat.Struct.Mol.Biol., 2024
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7A21
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![BU of 7a21 by Molmil](/molmil-images/mine/7a21) | Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2158 | 分子名称: | 1,2-ETHANEDIOL, 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, Activin receptor type I, ... | 著者 | Adamson, R.J, Williams, E.P, Smil, D, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | 登録日 | 2020-08-14 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2153 To Be Published
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3OJJ
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![BU of 3ojj by Molmil](/molmil-images/mine/3ojj) | Structure of Co-substituted Homoprotocatechuate 2,3-Dioxygenase from B.fuscum at 1.72 Ang resolution | 分子名称: | CALCIUM ION, CHLORIDE ION, COBALT (II) ION, ... | 著者 | Fielding, A.J, Kovaleva, E.G, Farquhar, E.R, Lipscomb, J.D, Que Jr, L. | 登録日 | 2010-08-23 | 公開日 | 2010-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | A hyperactive cobalt-substituted extradiol-cleaving catechol dioxygenase. J.Biol.Inorg.Chem., 16, 2011
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8VZQ
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![BU of 8vzq by Molmil](/molmil-images/mine/8vzq) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-406 | 分子名称: | (1S,2R,4S)-N-(2-fluoro-2-methylpropyl)-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor, NICKEL (II) ION | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-12 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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6QJO
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![BU of 6qjo by Molmil](/molmil-images/mine/6qjo) | DNA containing both right- and left-handed parallel-stranded G-quadruplexes | 分子名称: | DNA (28-MER), POTASSIUM ION | 著者 | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Schmitt, E, Mechulam, Y, Phan, A.T. | 登録日 | 2019-01-24 | 公開日 | 2019-07-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes. Nucleic Acids Res., 47, 2019
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4YGO
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![BU of 4ygo by Molmil](/molmil-images/mine/4ygo) | Dodecameric structure of spermidine N-acetyltransferase from Vibrio cholerae in intermediate state | 分子名称: | CALCIUM ION, METHANOL, Spermidine n1-acetyltransferase | 著者 | Filippova, E.V, Minasov, G, Kiryukhina, O, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-02-26 | 公開日 | 2015-10-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Substrate-Induced Allosteric Change in the Quaternary Structure of the Spermidine N-Acetyltransferase SpeG. J.Mol.Biol., 427, 2015
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7KKU
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![BU of 7kku by Molmil](/molmil-images/mine/7kku) | X-ray Counterpart to Neutron Structure of Oxidized Human MnSOD | 分子名称: | MANGANESE (III) ION, PHOSPHATE ION, Superoxide dismutase [Mn], ... | 著者 | Azadmanesh, J, Lutz, W.E, Coates, L, Weiss, K.L, Borgstahl, G.E.O. | 登録日 | 2020-10-28 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase. Nat Commun, 12, 2021
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7A70
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![BU of 7a70 by Molmil](/molmil-images/mine/7a70) | HEW lysozyme in complex with Ti(OH)4 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme, ... | 著者 | Calderone, V, Gigli, L, Ravera, E, Luchinat, C. | 登録日 | 2020-08-27 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | On the Mechanism of Bioinspired Formation of Inorganic Oxides: Structural Evidence of the Electrostatic Nature of the Interaction between a Mononuclear Inorganic Precursor and Lysozyme. Biomolecules, 11, 2020
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7SWL
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![BU of 7swl by Molmil](/molmil-images/mine/7swl) | CryoEM structure of the N-terminal-deleted Rix7 AAA-ATPase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S. | 登録日 | 2021-11-20 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly. Pnas Nexus, 1, 2022
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7T0V
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![BU of 7t0v by Molmil](/molmil-images/mine/7t0v) | CryoEM structure of the crosslinked Rix7 AAA-ATPase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S. | 登録日 | 2021-11-30 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly. Pnas Nexus, 1, 2022
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7KLB
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![BU of 7klb by Molmil](/molmil-images/mine/7klb) | X-ray Counterpart to Neutron Structure of Reduced Human MnSOD | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Azadmanesh, J, Lutz, W.E, Coates, L, Weiss, K.L, Borgstahl, G.E.O. | 登録日 | 2020-10-29 | 公開日 | 2021-04-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase. Nat Commun, 12, 2021
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8VRN
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![BU of 8vrn by Molmil](/molmil-images/mine/8vrn) | Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus PPTQ | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(4-methylphenyl)-2-phenylquinazolin-4(3H)-one, ... | 著者 | Chojnacka, W, Teng, J, Kim, J.J, Jensen, A.A, Hibbs, R.E. | 登録日 | 2024-01-22 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Structural insights into GABA A receptor potentiation by Quaalude. Nat Commun, 15, 2024
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3OOY
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![BU of 3ooy by Molmil](/molmil-images/mine/3ooy) | Crystal structure of human Transketolase (TKT) | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | 著者 | Krojer, T, Krysztofinska, E, Guo, K, Pilka, E, Kochan, G, Chaikuad, A, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Kavanagh, K, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2010-08-31 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of human Transketolase (TKT) To be Published
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6JL4
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![BU of 6jl4 by Molmil](/molmil-images/mine/6jl4) | Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with carbamoyl aspartate (CA) and phosphate (Pi) | 分子名称: | ASPARTIC ACID, Aspartate carbamoyltransferase, N-CARBAMOYL-L-ASPARTATE, ... | 著者 | Matoba, K, Shiba, T, Nara, T, Aoki, T, Nagasaki, S, Hayamizu, R, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Balogun, E.O, Inaoka, D.K, Kita, K, Harada, S. | 登録日 | 2019-03-04 | 公開日 | 2020-03-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystallographic snapshots of Trypanosoma cruzi aspartate transcarbamoylase
revealed an ordered Bi-Bi reaction mechanism To Be Published
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