PDB: 10097 件ウェブページステータス検索Chemie searchBIRD

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7X75	Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with three Zur dimers 分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, X, Zheng, J. 登録日 2022-03-09 公開日 2022-08-03 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
7MLI	Crystal structure of Thermus thermophilus reiterative transcription complex with 5nt oligo-C RNA 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*CP*TP*AP*CP*GP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*CP*GP*TP*AP*GP*GP*GP*CP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, Y, Ebright, R.H. 登録日 2021-04-28 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
7MLJ	Crystal structure of Thermus thermophilus reiterative transcription complex with 4nt oligo-G RNA 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*GP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*CP*GP*TP*GP*CP*CP*CP*TP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, Y, Ebright, R.H. 登録日 2021-04-28 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.75 Å) 主引用文献 Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
7X76	Cryo-EM structure of Streptomyces coelicolor RNAP-promoter open complex with two Zur dimers 分子名称: DNA (84-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yang, X, Zheng, J. 登録日 2022-03-09 公開日 2022-08-03 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Structural basis of Streptomyces transcription activation by zinc uptake regulator. Nucleic Acids Res., 50, 2022
4M5D	Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae 分子名称: Ribosomal RNA-processing protein 7, SULFATE ION, TRIETHYLENE GLYCOL, ... 著者 Lin, J, Ye, K. 登録日 2013-08-08 公開日 2013-11-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 An RNA-Binding Complex Involved in Ribosome Biogenesis Contains a Protein with Homology to tRNA CCA-Adding Enzyme. Plos Biol., 11, 2013
5N8X	Trigonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus 分子名称: 3D polymerase, GLYCEROL, MANGANESE (II) ION 著者 Ferrer-Orta, C, Verdaguer, N. 登録日 2017-02-24 公開日 2017-05-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus. Genome Biol Evol, 9, 2017
7KIN	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter 分子名称: DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
7KIM	Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor 分子名称: DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
7KIF	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor 分子名称: DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
1UON	REOVIRUS POLYMERASE LAMBDA-3 LOCALIZED BY ELECTRON CRYOMICROSCOPY OF VIRIONS AT 7.6-A RESOLUTION 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 5'-R(*GP*GP*GP*GP*GP*)-3', 5'-R(*UP*AP*GP*CP*CP*CP*CP*CP*)-3', ... 著者 Zhang, X, Walker, S.B, Chipman, P.R, Nibert, M.L, Baker, T.S. 登録日 2003-09-21 公開日 2003-11-13 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Reovirus Polymerase Lambda3 Localized by Cryo-Electron Microscopy of Virions at a Resolution of 7.6 A Nat.Struct.Biol., 10, 2003
7L7B	Clostridioides difficile RNAP with fidaxomicin 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Boyaci, H, Campbell, E.A, Darst, S.A, Chen, J. 登録日 2020-12-28 公開日 2022-02-02 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile. Nature, 604, 2022
8PEN	fully recruited RfaH bound to E. coli transcription complex paused at ops site (alternative state of RfaH) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. 登録日 2023-06-14 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
8PFJ	fully recruited RfaH bound to E. coli transcription complex paused at ops site (not fully complementary scaffold; alternative state of RfaH) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. 登録日 2023-06-16 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
8CWT	Complex structure of WhiB3 and the SigmaAr4-RNAP Beta flap tip chimera in space group P43212 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IRON/SULFUR CLUSTER, NICKEL (II) ION, ... 著者 Wan, T, Zhang, L. 登録日 2022-05-19 公開日 2023-05-17 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis. J.Biol.Chem., 299, 2023
8GWE	SARS-CoV-2 E-RTC complex with RNA-nsp9 and GMPPNP 分子名称: Helicase nsp13, MAGNESIUM ION, Non-structural protein 8, ... 著者 Yan, L.M, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-16 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWO	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: Helicase, Non-structural protein 7, Non-structural protein 8, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-11-30 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWG	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-12-14 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWI	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-12-14 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWN	A mechanism for SARS-CoV-2 RNA capping and its inhibitor of AT-527 分子名称: Helicase, Non-structural protein 7, Non-structural protein 8, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-12-14 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWF	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... 著者 Yan, L.Y, Huang, Y.C, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2023-01-11 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.39 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8CWR	Complex structure of WhiB3 and the SigmaAr4-RNAP Beta flap tip chimera in space group R3 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IRON/SULFUR CLUSTER, NICKEL (II) ION, ... 著者 Wan, T, Zhang, L. 登録日 2022-05-19 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis. J.Biol.Chem., 299, 2023
3C66	Yeast poly(A) polymerase in complex with Fip1 residues 80-105 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Poly(A) polymerase, ... 著者 Bohm, A, Meinke, G. 登録日 2008-02-02 公開日 2008-05-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically disordered protein. Biochemistry, 47, 2008
4G7O	Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA 分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.993 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012
6FHI	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer serine 5 phosphorylated Pol II CTD peptide with a truncated linker. 分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Lukarska, M, Cusack, S. 登録日 2018-01-14 公開日 2019-01-30 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
5FJ6	Structure of the P2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex 分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Ilca, S, Kotecha, A, Sun, X, Poranen, M.P, Stuart, D.I, Huiskonen, J.T. 登録日 2015-10-06 公開日 2015-11-04 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.9 Å) 主引用文献 Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes. Nat.Commun., 6, 2015

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