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8JB1
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Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Corynebacterium glutamicum ATCC13032 in complex with NADP
分子名称: GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Son, H.F, Kim, K.J.
登録日2023-05-07
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structure-based functional analysis of a novel NADPH-producing glyceraldehyde-3-phosphate dehydrogenase from Corynebacterium glutamicum.
Int.J.Biol.Macromol., 255, 2023
8JDK
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Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2023-05-14
公開日2023-12-06
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.26 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7JOZ
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Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist
分子名称: 6-{4-[(furo[3,2-c]pyridin-4-yl)oxy]-2-methylphenyl}-1,5-dimethylpyrimidine-2,4(1H,3H)-dione, Endolysin,D(1A) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Sun, B, Feng, D, Chu, M.L, Fish, I, Kelm, S, Lebon, F, Lovera, S, Valade, A, Wood, M, Ceska, T, Kobilka, T.S, Sands, Z, Kobilka, B.K.
登録日2020-08-07
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist.
Nat Commun, 12, 2021
8JDM
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Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2023-05-14
公開日2023-12-06
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7JY2
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Z-DNA joint X-ray/Neutron
分子名称: Chains: A,B
著者Harp, J.M, Coates, L, Egli, M.
登録日2020-08-28
公開日2021-04-28
最終更新日2024-04-03
実験手法NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION
主引用文献Water structure around a left-handed Z-DNA fragment analyzed by cryo neutron crystallography.
Nucleic Acids Res., 49, 2021
8JDL
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BU of 8jdl by Molmil
Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2023-05-14
公開日2023-12-06
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
3BHM
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BU of 3bhm by Molmil
Crystal structure of human Carbonyl Reductase 1 in complex with S-hydroxymethylglutathione
分子名称: 2-AMINO-4-[1-CARBOXYMETHYL-CARBAMOYL)-2-HYDROXYMETHYLSULFANYL-ETHYLCARBAMOYL]-BUTYRIC ACID, 3-(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)PHENOL, Carbonyl reductase [NADPH] 1, ...
著者Bateman, R.L, Rauh, D, Shokat, K.M.
登録日2007-11-28
公開日2008-10-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Human carbonyl reductase 1 is an s-nitrosoglutathione reductase
J.Biol.Chem., 283, 2008
8J5K
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Structural insights into photosystem II supercomplex and trimeric FCP antennae of a centric diatom Cyclotella meneghiniana
分子名称: (1~{R})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15-octaen-17-ynyl]cyclohex-3-en-1-ol, (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, ...
著者Shen, L.L, Li, Z.H, Shen, J.R, Wang, W.D.
登録日2023-04-23
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural insights into photosystem II supercomplex and trimeric FCP antennae of a centric diatom Cyclotella meneghiniana.
Nat Commun, 14, 2023
8JPZ
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The thermostability mutant Gox_M8 from Aspergillus niger
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Tu, T, Yan, Y.R.
登録日2023-06-13
公開日2023-12-20
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Revealing the pH-Dependent Activity Mechanism of a Ferrari Oxidoreductase Enzyme-Glucose Oxidase
To Be Published
8JDJ
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BU of 8jdj by Molmil
Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2023-05-14
公開日2023-12-06
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
3BHJ
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BU of 3bhj by Molmil
Crystal structure of human Carbonyl Reductase 1 in complex with glutathione
分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 3-(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)PHENOL, Carbonyl reductase [NADPH] 1, ...
著者Rauh, D, Bateman, R.L, Shokat, K.M.
登録日2007-11-28
公開日2008-10-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Human carbonyl reductase 1 is an s-nitrosoglutathione reductase
J.Biol.Chem., 283, 2008
7KCS
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BU of 7kcs by Molmil
The crystal structure of 4-vinylbenzoate-bound wild-type CYP199A4
分子名称: 4-ethenylbenzoic acid, CHLORIDE ION, Cytochrome P450, ...
著者Coleman, T, Bruning, J.B, Bell, S.G.
登録日2020-10-07
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.773 Å)
主引用文献Understanding the Mechanistic Requirements for Efficient and Stereoselective Alkene Epoxidation by a Cytochrome P450 Enzyme
Acs Catalysis, 11, 2021
8JQK
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BU of 8jqk by Molmil
Crystal structure of a carbonyl reductase SSCR mutant from Sporobolomyces Salmonicolor
分子名称: Aldehyde reductase 2
著者Zhang, H.L, Li, Q, Liu, W.D, Chen, X, Wu, Q.Q, Zhu, D.M.
登録日2023-06-14
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Engineering a Carbonyl Reductase to Simultaneously Increase Activity Toward Bulky Ketone and Isopropanol for Dynamic Kinetic Asymmetric Reduction via Enzymatic Hydrogen Transfer
Acs Catalysis, 13, 2023
7K14
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BU of 7k14 by Molmil
Ternary soak structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens with FMN and methanesulfonate
分子名称: Alkanesulfonate monooxygenase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Liew, J.J.M, Dowling, D.P, El Saudi, I.M.
登録日2020-09-07
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
8JC4
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BU of 8jc4 by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A-T268V in complex with Pyd-Pid-Phe and hydroxylamine
分子名称: 1-pyridin-4-ylpiperidine-4-carboxylic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ...
著者Jiang, Y, Dong, S, Feng, Y, Cong, Z.
登録日2023-05-10
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献C(sp3)-H hydroxylation of Broad-Spectrum Alkanes Catalyzed by an Artificial P450 Peroxygenase Driven by omega-Pyridyl Fatty Acyl Amino Acids.
Mol Catal, 550, 2023
7JYB
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BU of 7jyb by Molmil
Binary soak structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens with FMN
分子名称: Alkanesulfonate monooxygenase, FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, ...
著者Liew, J.J.M, Dowling, D.P, El Saudi, I.M.
登録日2020-08-30
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
8JC3
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BU of 8jc3 by Molmil
Crystal structure of the P450 BM3 heme domain mutant F87A-T268V in complex with Pyd-N-C4-Phe and hydroxylamine
分子名称: 4-(pyridin-4-ylamino)butanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ...
著者Jiang, Y, Dong, S, Feng, Y, Cong, Z.
登録日2023-05-10
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献C(sp3)-H hydroxylation of Broad-Spectrum Alkanes Catalyzed by an Artificial P450 Peroxygenase Driven by omega-Pyridyl Fatty Acyl Amino Acids.
Mol Catal, 550, 2023
8JQJ
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BU of 8jqj by Molmil
Crystal structure of carbonyl reductase SSCR mutant 1 from Sporobolomyces Salmonicolor
分子名称: Aldehyde reductase 2
著者Zhang, H.L, Li, Q, Liu, W.D, Chen, X, Wu, Q.Q, Zhu, D.M.
登録日2023-06-14
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Engineering a Carbonyl Reductase to Simultaneously Increase Activity Toward Bulky Ketone and Isopropanol for Dynamic Kinetic Asymmetric Reduction via Enzymatic Hydrogen Transfer
Acs Catalysis, 13, 2023
7JW9
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BU of 7jw9 by Molmil
Ternary cocrystal structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens
分子名称: Alkanesulfonate monooxygenase, FLAVIN MONONUCLEOTIDE, SODIUM ION, ...
著者Liew, J.J.M, Dowling, D.P.
登録日2020-08-25
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
7JV3
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BU of 7jv3 by Molmil
Crystal structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens
分子名称: Alkanesulfonate monooxygenase
著者Liew, J.J.M, Dowling, D.P.
登録日2020-08-20
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
7K88
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BU of 7k88 by Molmil
Crystal structure of bovine RPE65 in complex with hexaethylene glycol monooctyl ether
分子名称: 3,6,9,12,15,18-hexaoxahexacosan-1-ol, FE (II) ION, Retinoid isomerohydrolase, ...
著者Kiser, P.D.
登録日2020-09-26
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
J.Med.Chem., 64, 2021
7K64
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BU of 7k64 by Molmil
Binary titrated soak structure of alkanesulfonate monooxygenase MsuD from Pseudomonas fluorescens with FMN
分子名称: Alkanesulfonate monooxygenase, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Liew, J.J.M, Dowling, D.P.
登録日2020-09-18
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the alkanesulfonate monooxygenase MsuD provide insight into C-S bond cleavage, substrate scope, and an unexpected role for the tetramer.
J.Biol.Chem., 297, 2021
3C6G
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Crystal structure of CYP2R1 in complex with vitamin D3
分子名称: (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLI DENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Cytochrome P450 2R1, ...
著者Strushkevich, N.V, Min, J, Loppnau, P, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Plotnikov, A.N, Park, H, Structural Genomics Consortium (SGC)
登録日2008-02-04
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural analysis of CYP2R1 in complex with vitamin D3.
J.Mol.Biol., 380, 2008
7K8G
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Crystal structure of bovine RPE65 in complex with 4-fluoro-MB-004 and palmitate
分子名称: (1R)-3-amino-1-{4-fluoro-3-[(2-propylpentyl)oxy]phenyl}propan-1-ol, FE (II) ION, PALMITIC ACID, ...
著者Kiser, P.D.
登録日2020-09-27
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
J.Med.Chem., 64, 2021
7K89
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Crystal structure of bovine RPE65 in complex with 4-fluoro-emixustat and palmitate
分子名称: (1R)-3-amino-1-[3-(cyclohexylmethoxy)-4-fluorophenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ...
著者Kiser, P.D.
登録日2020-09-26
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
J.Med.Chem., 64, 2021

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件を2024-07-10に公開中

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