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5OTW
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BU of 5otw by Molmil
Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Hcs/Thr11Cys
分子名称: Glucagon, Glucagon-like peptide 1 receptor
著者Mortensen, S.
登録日2017-08-22
公開日2018-07-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4.
Biochemistry, 57, 2018
3C4O
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BU of 3c4o by Molmil
Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M/S130K/S146M complex
分子名称: Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION
著者Reynolds, K.A, Hanes, M.S, Thomson, J.M, Antczak, A.J, Berger, J.M, Bonomo, R.A, Kirsch, J.F, Handel, T.M.
登録日2008-01-30
公開日2008-05-27
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
2ANR
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BU of 2anr by Molmil
Crystal structure (II) of Nova-1 KH1/KH2 domain tandem with 25nt RNA hairpin
分子名称: 5'-R(*CP*(5BU)P*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*AP*AP*GP*CP*GP*AP*G)-3', MAGNESIUM ION, POTASSIUM ION, ...
著者Malinina, L, Teplova, M, Musunuru, K, Teplov, A, Darnell, J.C, Burley, S.K, Darnell, R.B, Patel, D.J.
登録日2005-08-11
公開日2006-10-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
Structure, 19, 2011
3NOO
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BU of 3noo by Molmil
Crystal Structure of C101A Isocyanide Hydratase from Pseudomonas fluorescens
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ThiJ/PfpI family protein
著者Lakshminarasimhan, M, Madzelan, P, Nan, R, Milkovic, N.M, Wilson, M.A.
登録日2010-06-25
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Evolution of New Enzymatic Function by Structural Modulation of Cysteine Reactivity in Pseudomonas fluorescens Isocyanide Hydratase.
J.Biol.Chem., 285, 2010
3BS9
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BU of 3bs9 by Molmil
X-ray structure of human TIA-1 RRM2
分子名称: IODIDE ION, Nucleolysin TIA-1 isoform p40
著者Kumar, A.O, Kielkopf, C.L.
登録日2007-12-22
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the central RNA recognition motif of human TIA-1 at 1.95A resolution.
Biochem.Biophys.Res.Commun., 367, 2008
1FG8
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BU of 1fg8 by Molmil
STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES
分子名称: N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE RETROPEPSIN
著者Mahalingam, B, Louis, J.M, Harrison, R.W, Weber, I.T.
登録日2000-07-25
公開日2001-06-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural implications of drug-resistant mutants of HIV-1 protease: high-resolution crystal structures of the mutant protease/substrate analogue complexes.
Proteins, 43, 2001
1RRB
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BU of 1rrb by Molmil
THE RAS-BINDING DOMAIN OF RAF-1 FROM RAT, NMR, 1 STRUCTURE
分子名称: RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE
著者Terada, T, Ito, Y, Shirouzu, M, Tateno, M, Hashimoto, K, Kigawa, T, Ebisuzaki, T, Takio, K, Shibata, T, Yokoyama, S, Smith, B.O, Laue, E.D, Cooper, J.A, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日1998-03-26
公開日1999-03-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance and molecular dynamics studies on the interactions of the Ras-binding domain of Raf-1 with wild-type and mutant Ras proteins.
J.Mol.Biol., 286, 1999
3DEA
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BU of 3dea by Molmil
Glomerella cingulata PETFP-cutinase complex
分子名称: 1,1,1-trifluoro-3-[(2-phenylethyl)sulfanyl]propan-2-one, Cutinase
著者Nyon, M.P, Rice, D.W, Berrisford, J.M, Hounslow, A.M, Moir, A.J.G, Huang, H, Nathan, S, Mahadi, N.M, Farah Diba, A.B, Craven, C.J.
登録日2008-06-09
公開日2008-11-18
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Catalysis by Glomerella cingulata Cutinase Requires Conformational Cycling between the Active and Inactive States of Its Catalytic Triad
J.Mol.Biol., 385, 2009
2H0B
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BU of 2h0b by Molmil
Crystal Structure of the second LNS/LG domain from Neurexin 1 alpha
分子名称: CALCIUM ION, GLYCEROL, Neurexin-1-alpha
著者Sheckler, L.R, Henry, L, Sugita, S, Sudhof, T.C, Rudenko, G.
登録日2006-05-14
公開日2006-06-20
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Second LNS/LG Domain from Neurexin 1{alpha}: Ca2+ binding and the effects of alternative splicing
J.Biol.Chem., 281, 2006
1RRG
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BU of 1rrg by Molmil
NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, DIMERIC CRYSTAL FORM
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAT ADP-RIBOSYLATION FACTOR-1
著者Greasley, S.E, Jhoti, H, Bax, B.
登録日1995-12-16
公開日1996-06-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms.
Nat.Struct.Biol., 2, 1995
3DIW
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BU of 3diw by Molmil
c-terminal beta-catenin bound TIP-1 structure
分子名称: Tax1-binding protein 3, decameric peptide form Catenin beta-1
著者Shen, Y.
登録日2008-06-21
公開日2008-10-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1
J.Mol.Biol., 384, 2008
3ZHX
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BU of 3zhx by Molmil
Structure of Mycobacterium tuberculosis DXR in complex with a fosmidomycin analogue
分子名称: 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, MANGANESE (II) ION, [(1S)-1-(3,4-dichlorophenyl)-3-[oxidanyl(phenylcarbonyl)amino]propyl]phosphonic acid
著者Bjorkelid, C, Jansson, A.M, Bergfors, T, Unge, T, Mowbray, S.L, Jones, T.A.
登録日2012-12-30
公開日2013-10-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dxr Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues.
J.Med.Chem., 56, 2013
1BW5
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BU of 1bw5 by Molmil
THE NMR SOLUTION STRUCTURE OF THE HOMEODOMAIN OF THE RAT INSULIN GENE ENHANCER PROTEIN ISL-1, 50 STRUCTURES
分子名称: INSULIN GENE ENHANCER PROTEIN ISL-1
著者Ippel, J.H, Larsson, G, Behravan, G, Zdunek, J, Lundqvist, M, Schleucher, J, Lycksell, P.-O, Wijmenga, S.S.
登録日1998-09-29
公開日1999-06-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of the homeodomain of the rat insulin-gene enhancer protein isl-1. Comparison with other homeodomains.
J.Mol.Biol., 288, 1999
1RWV
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BU of 1rwv by Molmil
Crystal structure of human caspase-1 in complex with 5-[5-(1-carboxymethyl-2-oxo-propylcarbamoyl)-5-phenyl-pentylsulfamoyl]-2-hydroxy-benzoic acid
分子名称: 5-[5-(1-CARBOXYMETHYL-2-OXO-PROPYLCARBAMOYL)-5-PHENYL-PENTYLSULFAMOYL]-2-HYDROXY-BENZOIC ACID, Interleukin-1 beta convertase
著者Romanowski, M.J, Burdett, M.T, Fahr, B.T, O'Brien, T.
登録日2003-12-17
公開日2004-12-28
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Novel Caspase-1 Inhibitors Discovered Using Tethering(SM) with Extenders
TO BE PUBLISHED
1JQ9
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Crystal structure of a complex formed between phospholipase A2 from Daboia russelli pulchella and a designed pentapeptide Phe-Leu-Ser-Tyr-Lys at 1.8 resolution
分子名称: ACETIC ACID, Peptide inhibitor, Phospholipase A2
著者Chandra, V, Jasti, J, Kaur, P, Dey, S, Betzel, C, Singh, T.P.
登録日2001-08-04
公開日2002-11-06
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A Resolution
J.BIOL.CHEM., 277, 2002
3SIX
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BU of 3six by Molmil
Crystal structure of NodZ alpha-1,6-fucosyltransferase soaked with GDP-fucose
分子名称: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Nodulation fucosyltransferase NodZ, ...
著者Brzezinski, K, Dauter, Z, Jaskolski, M.
登録日2011-06-20
公開日2012-02-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of NodZ alpha-1,6-fucosyltransferase in complex with GDP and GDP-fucose
Acta Crystallogr.,Sect.D, 68, 2012
3SMH
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BU of 3smh by Molmil
Crystal structure of major peanut allergen Ara h 1
分子名称: Allergen Ara h 1, clone P41B
著者Cabanos, C.S, Mikami, B, Maruyama, N.
登録日2011-06-28
公開日2012-02-15
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.433 Å)
主引用文献Crystal structure of the major peanut allergen Ara h 1.
Mol.Immunol., 49, 2011
2OQB
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Crystal structure of the N-terminal domain of coactivator-associated methyltransferase 1 (CARM1)
分子名称: CHLORIDE ION, Histone-arginine methyltransferase CARM1
著者Cavarelli, J.
登録日2007-01-31
公開日2007-10-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains.
Embo J., 26, 2007
4FWW
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BU of 4fww by Molmil
Crystal structure of the Sema-PSI extracellular domains of human RON receptor tyrosine kinase
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Chao, K.L, Herzberg, O.
登録日2012-07-02
公開日2012-08-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of the Sema-PSI Extracellular Domain of Human RON Receptor Tyrosine Kinase.
Plos One, 7, 2012
3TX7
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Crystal structure of LRH-1/beta-catenin complex
分子名称: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Catenin beta-1, Nuclear receptor subfamily 5 group A member 2
著者Yumoto, F, Fletterick, R.
登録日2011-09-22
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structural basis of coactivation of liver receptor homolog-1 by beta-catenin.
Proc.Natl.Acad.Sci.USA, 109, 2012
3N0Q
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Crystal structure of a Putative aromatic-ring hydroxylating dioxygenase (TM1040_3219) from SILICIBACTER SP. TM1040 at 1.80 A resolution
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2010-05-14
公開日2010-06-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a Putative aromatic-ring hydroxylating dioxygenase (TM1040_3219) from SILICIBACTER SP. TM1040 at 1.80 A resolution
To be published
4OEM
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Crystal structure of Cathepsin C in complex with dipeptide substrates
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Zhao, B, Smallwood, A, Concha, N.
登録日2014-01-13
公開日2015-03-25
最終更新日2025-05-21
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis.
Biochemistry, 51, 2012
3N45
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Human FPPS complex with FBS_04 and zoledronic acid/MG2+
分子名称: (2S)-1-[(benzyloxy)carbonyl]-2,3-dihydro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, MAGNESIUM ION, ...
著者Rondeau, J.-M.
登録日2010-05-21
公開日2010-08-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.
Nat.Chem.Biol., 6, 2010
1ZA4
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Crystal Structure of the Thrombospondin-1 N-terminal Domain in Complex with Arixtra
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, SULFATE ION, Thrombospondin 1
著者Tan, K, Wang, J.H, Lawler, J.
登録日2005-04-05
公開日2006-01-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Structures of the Thrombospondin-1 N-terminal Domain and its Complex with a Synthetic Pentameric Heparin
Structure, 14, 2006
1FFI
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STRUCTURAL IMPLICATIONS OF DRUG RESISTANT MUTANTS OF HIV-1 PROTEASE: HIGH RESOLUTION CRYSTAL STRUCTURES OF THE MUTANT PROTEASE/SUBSTRATE ANALOG COMPLEXES
分子名称: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, PROTEASE RETROPEPSIN
著者Mahalingam, B, Louis, J.M, Harrison, R.W, Weber, I.T.
登録日2000-07-25
公開日2001-06-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural implications of drug-resistant mutants of HIV-1 protease: high-resolution crystal structures of the mutant protease/substrate analogue complexes.
Proteins, 43, 2001

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