9FWX
| Crystal structure of BRD4 BD1 with MEN1404BS. | 分子名称: | 3-methyl-~{N}-(2-phenylethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-amine, Bromodomain-containing protein 4 | 著者 | Bader, G, Kessler, D. | 登録日 | 2024-07-01 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Probing Protein-Ligand Methyl-pi Interaction Geometries through Chemical Shift Measurements of Selectively Labeled Methyl Groups. J.Med.Chem., 2024
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9G2R
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4K7U
| Crystal structure of Zn2.3-hUb (human ubiquitin) adduct from a solution 70 mM zinc acetate/1.3 mM hUb | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G. | 登録日 | 2013-04-17 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Conformational selection of ubiquitin quaternary structures driven by zinc ions. Chemistry, 19, 2013
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9G2W
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9CBE
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4K2Y
| Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-chloro-1,3-dihydro-2H-indol-2-one | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloro-1,3-dihydro-2H-indol-2-one, Chymase, ... | 著者 | Collins, B.K, Padyana, A.K. | 登録日 | 2013-04-09 | 公開日 | 2013-05-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies. J.Med.Chem., 56, 2013
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9BR6
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9FDK
| Crystal Structure of oxidized NuoEF variant R66G(NuoF) from Aquifex aeolicus | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Wohlwend, D, Friedrich, T, Goeppert-Asadollahpour, S. | 登録日 | 2024-05-17 | 公開日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural robustness of the NADH binding site in NADH:ubiquinone oxidoreductase (complex I). Biochim Biophys Acta Bioenerg, 1865, 2024
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4K8W
| An arm-swapped dimer of the S. pyogenes pilin specific assembly factor SipA | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, LepA | 著者 | Young, P.G, Kang, H.J, Baker, E.N. | 登録日 | 2013-04-19 | 公開日 | 2013-06-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | An arm-swapped dimer of the Streptococcus pyogenes pilin specific assembly factor SipA. J.Struct.Biol., 183, 2013
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9CGM
| The Structure of Spiroplasma Virus 4 | 分子名称: | Capsid protein VP1, DNA binding protein ORF8 | 著者 | Mietzsch, M, McKenna, R. | 登録日 | 2024-06-30 | 公開日 | 2024-07-17 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | 主引用文献 | The Structure of Spiroplasma Virus 4 : Exploring the Capsid Diversity of the Microviridae. Viruses, 16, 2024
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9FX4
| Crystal structure of Cryo2RT Thaumatin at 100K | 分子名称: | L(+)-TARTARIC ACID, Thaumatin I | 著者 | Huang, C.Y, Aumonier, S, Olieric, V, Wang, M. | 登録日 | 2024-07-01 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Cryo2RT: a high-throughput method for room-temperature macromolecular crystallography from cryo-cooled crystals. Acta Crystallogr D Struct Biol, 80, 2024
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9G0K
| CysG(N-16) in complex with SAH (metal free, cocrystallization in presence of EDTA) from Kitasatospora cystarginea | 分子名称: | 1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, SAM-dependent methyltransferase | 著者 | Kuttenlochner, W, Beller, P, Kaysser, L, Groll, M. | 登録日 | 2024-07-08 | 公開日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Deciphering the SAM- and Metal-Dependent Mechanism of O-Methyltransferases in Cystargolide and Belactosin Biosynthesis: A Structure-Activity Relationship Study to be published
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9FJE
| Expanded formalin inactivated CVB1 | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | 著者 | Plavec, Z, Butcher, S.J. | 登録日 | 2024-05-31 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Comparison of structure and immunogenicity of CVB1-VLP and inactivated CVB1 vaccine candidates. Res Sq, 2024
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4KB4
| Crystal structure of ribosome recycling factor mutant R31A from Mycobacterium tuberculosis | 分子名称: | CADMIUM ION, Ribosome-recycling factor | 著者 | Selvaraj, M, Govindan, A, Seshadri, A, Dubey, B, Varshney, U, Vijayan, M. | 登録日 | 2013-04-23 | 公開日 | 2014-03-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Molecular flexibility of Mycobacterium tuberculosis ribosome recycling factor and its functional consequences: an exploration involving mutants. J.Biosci., 38, 2013
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9BPF
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9CIL
| Crystal structure of Staphylococcal nuclease variant Delta+PHS T41V/S59A at cryogenic temperature | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | 著者 | Zhang, Y, Schlessman, J.L, Siegler, M.A, Garcia-Moreno E, B. | 登録日 | 2024-07-03 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of Staphylococcal nuclease variant Delta+PHS T41V/S59A at cryogenic temperature To Be Published
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9CIK
| Crystal structure of Staphylococcal nuclease variant Delta+PHS V23R/L36D at cryogenic temperature | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | 著者 | Zhang, Y, Schlessman, J.L, SIegler, M.A, Garcia-Moreno E, B. | 登録日 | 2024-07-03 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23R/L36D at cryogenic temperature To Be Published
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9BOR
| IkappaBzeta ankyrin repeat domain:NF-kappaB p50 homodimer complex at 2.0 Angstrom resolution | 分子名称: | (2R,3S)-heptane-1,2,3-triol, NF-kappa-B inhibitor zeta, Nuclear factor NF-kappa-B p50 subunit | 著者 | Rogers, W.E, Zhu, N, Huxford, T. | 登録日 | 2024-05-05 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural and biochemical analyses of the nuclear I kappa B zeta protein in complex with the NF-kappa B p50 homodimer. Genes Dev., 38, 2024
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9CII
| Crystal structure of Staphylococcal nuclease variant Delta+PHS V23D/L36R at cryogenic temperature | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | 著者 | Zhang, Y, Schlessman, J.L, Robinson, A.C, Garcia-Moreno E, B. | 登録日 | 2024-07-03 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23D/L36R at cryogenic temperature To Be Published
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4K8H
| OYE1-W116V complexed with (R)-carvone | 分子名称: | (5R)-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-one, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | Sullivan, B, Pompeu, Y.A, Stewart, J.D. | 登録日 | 2013-04-18 | 公開日 | 2013-10-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | X‑ray Crystallography Reveals How Subtle Changes Control the
Orientation of Substrate Binding in an Alkene Reductase ACS CATALYSIS, 3, 2013
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6DLL
| 2.2 Angstrom Resolution Crystal Structure of P-Hydroxybenzoate Hydroxylase from Pseudomonas putida in Complex with FAD. | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, ... | 著者 | Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-06-01 | 公開日 | 2018-06-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural comparison of p-hydroxybenzoate hydroxylase (PobA) from Pseudomonas putida with PobA from other Pseudomonas spp. and other monooxygenases. Acta Crystallogr.,Sect.F, 75, 2019
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4KCG
| Human dCK C4S-S74E mutant in complex with UDP and the DI-39 inhibitor | 分子名称: | Deoxycytidine kinase, N-{2-[5-(4-{[(4,6-diaminopyrimidin-2-yl)sulfanyl]methyl}-5-propyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]ethyl}methanesulfonamide, URIDINE-5'-DIPHOSPHATE | 著者 | Nomme, J, Lavie, A. | 登録日 | 2013-04-24 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication. J.Exp.Med., 211, 2014
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9CWL
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9BOO
| Crystal structure of MERS-CoV Nsp5 in complex with PF-07817883 | 分子名称: | 3C-like proteinase nsp5, N-(methoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-(trifluoromethyl)-L-prolinamide | 著者 | Chen, P, Arutyunova, E, Lemieux, M.J. | 登録日 | 2024-05-05 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A Structural Comparison of Oral SARS-CoV-2 Drug Candidate Ibuzatrelvir Complexed with the Main Protease (Mpro) of SARS-CoV-2 and MERS-CoV Jacs Au, 2024
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9BXA
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