PDB: 36939 件ウェブページステータス検索Chemie searchBIRD

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6GKD	human NBD1 of CFTR in complex with nanobodies D12 and G3a 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, GLYCEROL, ... 著者 Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. 登録日 2018-05-18 公開日 2019-06-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
6H35	Myxococcus xanthus MglA bound to GDP and Pi with mixed inactive and active switch region conformations 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-DIPHOSPHATE, Mutual gliding-motility protein MglA, ... 著者 Varela, P.F, Galicia, C, Cherfils, J. 登録日 2018-07-17 公開日 2019-12-04 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus. Nat Commun, 10, 2019
4DTY	cytochrome P450 BM3h-8C8 MRI sensor, no ligand 分子名称: MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 BM3 variant 8C8 著者 Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H. 登録日 2012-02-21 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin. J.Mol.Biol., 422, 2012
4DJX	Structure of BACE Bound to 5-(3-(5-chloropyridin-3-yl)phenyl)-5-cyclopropyl-2-imino-3-methylimidazolidin-4-one 分子名称: (2E,5R)-5-[3-(5-chloropyridin-3-yl)phenyl]-5-cyclopropyl-2-imino-3-methylimidazolidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID 著者 Strickland, C, Cumming, J. 登録日 2012-02-02 公開日 2012-03-21 最終更新日 2012-04-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor. Bioorg.Med.Chem.Lett., 22, 2012
6GQW	KRAS-169 Q61H GPPNHP + CH-1 分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Phillips, S.E.V, Rabbitts, T.H. 登録日 2018-06-08 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6GFS	Thermodynamic, Crystallographic and Computational Studies of Non Mammalian Fatty Acid Binding to Bovine b-Lactoglobulin 分子名称: Beta-lactoglobulin, CHLORIDE ION, PENTADECANOIC ACID 著者 Kontopidis, G, Rovoli, M. 登録日 2018-05-02 公開日 2018-06-20 最終更新日 2018-07-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Thermodynamic, crystallographic and computational studies of non-mammalian fatty acid binding to bovine beta-Lactoglobulin. Int. J. Biol. Macromol., 118, 2018
4DMU	Crystal structure of the von Willebrand factor A3 domain in complex with a collagen III derived triple-helical peptide 分子名称: Collagen III derived triple-helical peptide, SULFATE ION, von Willebrand factor 著者 Brondijk, T.H.C, Huizinga, E.G. 登録日 2012-02-08 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex. Proc.Natl.Acad.Sci.USA, 109, 2012
3MZS	Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol 分子名称: (3alpha,8alpha,22R)-cholest-5-ene-3,22-diol, Cholesterol side-chain cleavage enzyme, ISOPROPYL ALCOHOL, ... 著者 Stout, C.D, Annalora, A, Mast, N, Pikuleva, I. 登録日 2010-05-12 公開日 2010-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1. J.Biol.Chem., 286, 2011
6G5A	Heme-carbene complex in myoglobin H64V/V68A containing an N-methylhistidine as the proximal ligand, 1.48 angstrom resolution 分子名称: ETHYL ACETATE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE 著者 Tinzl, M, Hayashi, T, Mori, T, Hilvert, D. 登録日 2018-03-29 公開日 2018-08-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.483 Å) 主引用文献 Capture and characterization of a reactive haem-carbenoid complex in an artificial metalloenzyme Nat Catal, 1, 2018
4DWT	Carbonmonoxy dehaloperoxidase-hemoglobin A structure at 2.05 Angstrom resolution 分子名称: CARBON MONOXIDE, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 de Serrano, V.S, Zhao, J, Franzen, S. 登録日 2012-02-26 公開日 2013-02-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A unique role for the distal histidine observed in carbonmonoxy dehaloperoxidase-hemoglobin A structures To be Published
4DQG	Crystal Structure of apo(G16C/L38C) HIV-1 Protease 分子名称: ACETATE ION, Aspartyl protease, GLYCEROL, ... 著者 Schiffer, C.A, Mittal, S. 登録日 2012-02-15 公開日 2012-03-07 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease. J.Am.Chem.Soc., 134, 2012
7E1H	crystal structure of RD-BEF 分子名称: BERYLLIUM TRIFLUORIDE ION, DNA-binding response regulator, MAGNESIUM ION 著者 Hong, S, Zhang, X, Zhang, P. 登録日 2021-02-01 公開日 2022-02-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.805 Å) 主引用文献 Structural basis of phosphorylation-induced activation of the response regulator VbrR. Acta Biochim.Biophys.Sin., 2023
4DC8	Crystal Structure of Myoglobin Unexposed to Excessive SONICC Imaging Laser Dose. 分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Becker, M, Mulichak, A.M, Kissick, D.J, Fischetti, R.F, Keefe, L.J, Simpson, D.J. 登録日 2012-01-17 公開日 2013-01-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Towards protein-crystal centering using second-harmonic generation (SHG) microscopy. Acta Crystallogr.,Sect.D, 69, 2013
7DY3	High resolution crystal structure of hemoglobin M Iwate. 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Ohki, M, Park, S.-Y. 登録日 2021-01-20 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 High resolution crystal structure of hemoglobin M Iwate. To Be Published
4DCF	Structure of MTX-II from Bothrops brazili 分子名称: MTX-II chain A, TETRAETHYLENE GLYCOL 著者 Ullah, A, Souza, T.A.C.B, Betzel, C, Murakami, M.T, Arni, R.K. 登録日 2012-01-17 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystallographic portrayal of different conformational states of a Lys49 phospholipase A2 homologue: insights into structural determinants for myotoxicity and dimeric configuration. Int.J.Biol.Macromol., 51, 2012
4DGR	Influenza Subtype 9 Neuraminidase Benzoic Acid Inhibitor Complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[2,2-bis(hydroxymethyl)-5-oxopyrrolidin-1-yl]-3-[(dipropylamino)methyl]benzoic acid, CALCIUM ION, ... 著者 Venkatramani, L, Johnson, E, Kolavi, G, Air, G.M, Brouillette, W, Mooers, B.H.M. 登録日 2012-01-26 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking sub-site C6. Bmc Struct.Biol., 12, 2012
4DD3	EVAL processed HEWL, carboplatin aqueous paratone 分子名称: 2-methylprop-1-ene, CHLORIDE ION, Lysozyme C 著者 Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. 登録日 2012-01-18 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein. Acta Crystallogr.,Sect.D, 68, 2012
3NBT	Crystal structure of trimeric cytochrome c from horse heart 分子名称: Cytochrome c, DI(HYDROXYETHYL)ETHER, HEME C, ... 著者 Taketa, M, Komori, H, Hirota, S, Higuchi, Y. 登録日 2010-06-04 公開日 2010-07-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Cytochrome c polymerization by successive domain swapping at the C-terminal helix Proc.Natl.Acad.Sci.USA, 107, 2010
7DY4	High resolution crystal structure of hemoglobin M Boston. 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Ohki, M, Park, S.-Y. 登録日 2021-01-20 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 High resolution crystal structure of hemoglobin M Boston. To Be Published
4DNJ	The crystal structures of 4-methoxybenzoate bound CYP199A2 分子名称: 4-METHOXYBENZOIC ACID, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Zhou, W, Bell, S.G, Yang, W, Tan, A.B.H, Zhou, R, Johnson, E.O.D, Zhang, A, Rao, Z, Wong, L.-L. 登録日 2012-02-08 公開日 2012-08-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding site Dalton Trans, 41, 2012
6FRO	Crystal structure of Hen Egg-White Lysozyme co-crystallized in presence of 100 mM Tb-Xo4 and 100 mM potassium iodide. 分子名称: IODIDE ION, Lysozyme C, SODIUM ION, ... 著者 Engilberge, S, Riobe, F, Di Pietro, S, Girard, E, Dumont, E, Maury, O. 登録日 2018-02-16 公開日 2018-10-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Unveiling the Binding Modes of the Crystallophore, a Terbium-based Nucleating and Phasing Molecular Agent for Protein Crystallography. Chemistry, 24, 2018
4DNZ	The crystal structures of CYP199A4 分子名称: CHLORIDE ION, Cytochrome P450, GLYCEROL, ... 著者 Zhou, W, Bell, S.G, Yang, W, Tan, A.B.H, Zhou, R, Johnson, E.O.D, Zhang, A, Rao, Z, Wong, L.-L. 登録日 2012-02-09 公開日 2012-08-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding site Dalton Trans, 41, 2012
3O7N	The V59W mutation blocks the distal pocket of the hemoglobin - dehaloperoxidase from Amphitrite ornata 分子名称: 4-BROMOPHENOL, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 de Serrano, V.S, Davis, M.F, Franzen, S. 登録日 2010-07-30 公開日 2011-07-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 The V59W mutation blocks the distal pocket of the hemoglobin - dehaloperoxidase from Amphitirite ornata To be Published
4DQC	Crystal Structure of (G16C/L38C) HIV-1 Protease in Complex with DRV 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Aspartyl protease, GLYCEROL, ... 著者 Schiffer, C.A, Mittal, S. 登録日 2012-02-15 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease. J.Am.Chem.Soc., 134, 2012
6FUG	Complement factor D in complex with the inhibitor 3-((3-((3-(aminomethyl)phenyl)amino)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)phenol 分子名称: 3-[[3-[[3-(aminomethyl)phenyl]amino]-1~{H}-pyrazolo[3,4-d]pyrimidin-4-yl]amino]phenol, Complement factor D 著者 Mac Sweeney, A, Ostermann, N, Vulpetti, A, Maibaum, J, Erbel, P, Lorthiois, E, Yoon, T, Randl, S, Ruedisser, S. 登録日 2018-02-27 公開日 2018-06-06 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D. ACS Med Chem Lett, 9, 2018

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