PDB: 30805 件ウェブページステータス検索Chemie searchBIRD

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7TII	Annealed structure of oxidized bovine cytochrome c oxidase with reduced metal centers induced by synchrotron X-ray exposure 分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... 著者 Ishigami, I, Rousseau, D.L, Yeh, S.-R, Russi, S, Cohen, A. 登録日 2022-01-13 公開日 2022-03-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Temperature-dependent structural transition following X-ray-induced metal center reduction in oxidized cytochrome c oxidase. J.Biol.Chem., 298, 2022
6PM7	The structure of the triclinic crystal form of beef liver catalase at 1.85 A resolution 分子名称: Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE 著者 McPherson, A. 登録日 2019-07-01 公開日 2020-05-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The structure of the triclinic crystal form of beef liver catalase at 1.85 A resolution to be published
7TQR	Crystal Structure of histidine ammonia lyase from Thermoplasma acidophilum 分子名称: Probable histidine ammonia-lyase 著者 Wu, K, Dulchavsky, M, Bardwell, J.C.A. 登録日 2022-01-26 公開日 2022-04-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Microreactor equipped with naturally acid-resistant histidine ammonia lyase from an extremophile. Mater Adv, 3, 2022
6B15	Crystal structure of CBMbc (family CBM26) from Eubacterium rectale Amy13K 分子名称: 1,2-ETHANEDIOL, Amy13K 著者 Cockburn, D.W, Wawrzak, Z, Perez Medina, K, Koropatkin, N.M. 登録日 2017-09-16 公開日 2017-11-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Novel carbohydrate binding modules in the surface anchored alpha-amylase of Eubacterium rectale provide a molecular rationale for the range of starches used by this organism in the human gut. Mol. Microbiol., 107, 2018
6N0M	CRYSTAL STRUCTURE OF SESTRIN2 IN COMPLEX WITH NV-0005138 分子名称: 4-(difluoromethyl)-L-leucine, Sestrin-2 著者 O'Neill, D. 登録日 2018-11-07 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Discovery of NV-5138, the first selective Brain mTORC1 activator. Sci Rep, 9, 2019
5ADB	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((4-Chloro-3-((methylamino)methyl)phenoxy)methyl) quinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[[4-chloranyl-3-(methylaminomethyl)phenoxy]methyl]quinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2015-08-20 公開日 2015-10-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
8DB1	Crystal structure of native DMATS1 prenyltransferase 分子名称: Dimethylallyltryptophan synthase 1, TRYPTOPHAN 著者 Eaton, S.A, Ronnebaum, T.A, Roose, B.W, Christianson, D.W. 登録日 2022-06-14 公開日 2022-09-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Structural Basis of Substrate Promiscuity and Catalysis by the Reverse Prenyltransferase N -Dimethylallyl-l-tryptophan Synthase from Fusarium fujikuroi . Biochemistry, 61, 2022
6PMY	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(3-(2-Aminoethyl)phenyl)-4-methylquinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[3-(2-aminoethyl)phenyl]-4-methylquinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2019-07-02 公開日 2020-04-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate. J.Med.Chem., 63, 2020
7P4P	Structure of the quinolinate synthase A84L variant complexed with citrate 分子名称: CHLORIDE ION, CITRATE ANION, IRON/SULFUR CLUSTER, ... 著者 Volbeda, A. 登録日 2021-07-12 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Transient Formation of a Second Active Site Cavity during Quinolinic Acid Synthesis by NadA. Acs Chem.Biol., 16, 2021
6PN9	Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(thiazol-5-ylmethoxy)phenyl)-4-methylquinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-{3-(aminomethyl)-4-[(1,3-thiazol-5-yl)methoxy]phenyl}-4-methylquinolin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2019-07-02 公開日 2020-04-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate. J.Med.Chem., 63, 2020
5A2O	Crystal structure of the nitrate transporter NRT1.1 from Arabidopsis thaliana in complex with nitrate. 分子名称: NITRATE ION, NITRATE TRANSPORTER 1.1 著者 Parker, J.L, Newstead, S. 登録日 2015-05-20 公開日 2015-06-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.71 Å) 主引用文献 Molecular Basis of Nitrate Uptake by the Plant Nitrate Transporter Nrt1.1. Nature, 507, 2014
7U69	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Phenethyl Piperidine-4-acrylhydroxamic Acid Inhibitor 分子名称: (2E)-N-hydroxy-3-[1-(2-phenylethyl)piperidin-4-yl]prop-2-enamide, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2022-03-03 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur.J.Med.Chem., 234, 2022
5A36	Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. 分子名称: ALPHA-ACTININ-2 著者 Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. 登録日 2015-05-27 公開日 2016-06-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation. Biochem.J., 473, 2016
5ACV	VIM-2-OX, Discovery of novel inhibitor scaffolds against the metallo- beta-lactamase VIM-2 by SPR based fragment screening 分子名称: BETA-LACTAMASE, CHLORIDE ION, HYDROXIDE ION, ... 著者 Christopeit, T, Carlsen, T.J.O, Helland, R, Leiros, H.K.S. 登録日 2015-08-18 公開日 2015-11-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.963 Å) 主引用文献 Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening J.Med.Chem., 58, 2015
7U3M	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with N-methylpiperazine Benzhydroxamic Acid 分子名称: N-hydroxy-4-[(4-methylpiperazin-1-yl)methyl]benzamide, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2022-02-27 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur.J.Med.Chem., 234, 2022
7U6A	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 3-thienylmethyl Benzhydroxamic Acid Inhibitor 分子名称: 1,2-ETHANEDIOL, N-hydroxy-4-({[(thiophen-3-yl)methyl]amino}methyl)benzamide, PHOSPHATE ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2022-03-03 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells. Eur.J.Med.Chem., 234, 2022
6PMP	Crystal structure of a fragment of rat phospholipase Cepsilon EF3-RA1 分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1, CALCIUM ION 著者 Rugema, N.Y, Lyon, A.M. 登録日 2019-07-02 公開日 2020-07-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Structure of phospholipase C epsilon reveals an integrated RA1 domain and previously unidentified regulatory elements. Commun Biol, 3, 2020
5AED	A bacterial protein structure in glycoside hydrolase family 31 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-GLUCOSIDASE YIHQ, CALCIUM ION 著者 Jin, Y, Speciale, G, Davies, G.J, Williams, S.J, Goddard-Borger, E.D. 登録日 2015-08-28 公開日 2016-02-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Yihq is a Sulfoquinovosidase that Cleaves Sulfoquinovosyl Diacylglyceride Sulfolipids. Nat.Chem.Biol., 12, 2016
7TLX	Crystal Structure of cytochrome c from Pseudomonas putida S16 分子名称: C-type cytochrome, HEME C 著者 Wu, K, Dulchavsky, M, Stull, F, Bardwell, J.C.A. 登録日 2022-01-19 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The enzyme pseudooxynicotine amine oxidase from Pseudomonas putida S16 is not an oxidase, but a dehydrogenase. J.Biol.Chem., 298, 2022
7P6V	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH compound 3ag 分子名称: Bromodomain-containing protein 4, ethyl 2-(2-(4-azido-N-((2-(1,5-dimethyl-6-oxo-1,6-dihydropyridin-3-yl)-1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-benzo[d]imidazol-6-yl)methyl)-2,3,5,6-tetrafluorobenzamido)acetamido)acetate 著者 Chung, C. 登録日 2021-07-18 公開日 2021-10-06 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 One-Step Synthesis of Photoaffinity Probes for Live-Cell MS-Based Proteomics. Chemistry, 27, 2021
8DYH	IL17A homodimer bound to Compound 6 分子名称: (5P)-N-benzyl-6-chloro-5-(quinolin-5-yl)pyridin-3-amine, GLYCEROL, Interleukin-17A 著者 Argiriadi, M.A, Goedken, E.R. 登録日 2022-08-04 公開日 2022-09-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site. Sci Rep, 12, 2022
6PO5	Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 7-(3-(Aminomethyl)-4-(cyclobutylmethoxy)phenyl)-4-methylquinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[3-(aminomethyl)-4-(cyclobutylmethoxy)phenyl]-4-methylquinolin-2-amine, GLYCEROL, ... 著者 Li, H, Poulos, T.L. 登録日 2019-07-03 公開日 2020-04-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate. J.Med.Chem., 63, 2020
6VES	Human insulin analog: [GluB10,HisA8,ArgA9]-DOI 分子名称: Insulin A chain, Insulin B chain 著者 Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X. 登録日 2020-01-02 公開日 2020-11-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mini-Ins: A Minimal, Bioactive Insulin Analog with Alternative Binding Modes To Be Published
7TOK	Crystal structure of the CBM domain of carbohydrate esterase FjoAcXE 分子名称: Acetylxylan esterase I 著者 Stogios, P.J, Skarina, T, Di Leo, R, Jurak, E, Master, E. 登録日 2022-01-24 公開日 2022-04-13 最終更新日 2022-11-02 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans. Molecules, 27, 2022
6PPV	Structure of S. pombe Lsm1-7 with RNA, polyuridine with 3' guanosine 分子名称: Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, RNA (5'-R(*AP*UP*UP*UP*UP*G)-3'), ... 著者 Montemayor, E.J, Butcher, S.E. 登録日 2019-07-08 公開日 2020-06-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020

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