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8B8A
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Multimerization domain of borna disease virus 1 phosphoprotein
分子名称: Phosphoprotein
著者Tarbouriech, N, Legrand, P, Bourhis, J.M, Chenavier, F, Freslon, L, Kawasaki, J, Horie, M, Tomonaga, K, Bachiri, K, Coyaud, E, Gonzalez-Dunia, D, Ruigrok, R.W.H, Crepin, T.
登録日2022-10-04
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing.
Viruses, 14, 2022
5M1S
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BU of 5m1s by Molmil
Cryo-EM structure of the E. coli replicative DNA polymerase-clamp-exonuclase-theta complex bound to DNA in the editing mode
分子名称: DNA Primer Strand, DNA Template Strand, DNA polymerase III subunit alpha, ...
著者Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H.
登録日2016-10-10
公開日2017-01-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Self-correcting mismatches during high-fidelity DNA replication.
Nat. Struct. Mol. Biol., 24, 2017
1ESH
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BU of 1esh by Molmil
THE SOLUTION STRUCTURE OF THE STEM LOOP C 5'AUA3' TRILOOP OF BROME MOSAIC VIRUS (+) STRAND RNA
分子名称: RNA (5'-R(*GP*GP*UP*GP*CP*AP*UP*AP*GP*CP*AP*CP*C)-3')
著者Kim, C.-H, Kao, C.C, Tinoco Jr, I.
登録日2000-04-10
公開日2000-04-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献RNA motifs that determine specificity between a viral replicase and its promoter.
Nat.Struct.Biol., 7, 2000
2N3Q
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BU of 2n3q by Molmil
NMR structure of the II-III-VI three-way junction from the VS ribozyme
分子名称: RNA (62-MER)
著者Bonneau, E, Girard, N, Lemieux, S, Legault, P.
登録日2015-06-09
公開日2015-07-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The NMR structure of the II-III-VI three-way junction from the Neurospora VS ribozyme reveals a critical tertiary interaction and provides new insights into the global ribozyme structure.
Rna, 21, 2015
1DUH
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BU of 1duh by Molmil
CRYSTAL STRUCTURE OF THE CONSERVED DOMAIN IV OF E. COLI 4.5S RNA
分子名称: 4.5S RNA DOMAIN IV, LUTETIUM (III) ION, MAGNESIUM ION, ...
著者Jovine, L, Hainzl, T, Oubridge, C, Scott, W.G, Li, J, Sixma, T.K, Wonacott, A, Skarzynski, T, Nagai, K.
登録日2000-01-17
公開日2000-05-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA.
Structure Fold.Des., 8, 2000
5IP9
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BU of 5ip9 by Molmil
Structure of RNA Polymerase II-TFIIF complex
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P.
登録日2016-03-09
公開日2016-05-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Transcription initiation complex structures elucidate DNA opening.
Nature, 533, 2016
4MEY
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BU of 4mey by Molmil
Crystal structure of Escherichia coli RNA polymerase holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H.
登録日2013-08-27
公開日2014-05-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.948 Å)
主引用文献Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
6XEZ
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BU of 6xez by Molmil
Structure of SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
著者Chen, J, Malone, B, Llewellyn, E.C, Campbell, E.A, Darst, S.A.
登録日2020-06-14
公開日2020-07-29
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex.
Cell, 182, 2020
7RWI
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BU of 7rwi by Molmil
Mycobacterium tuberculosis RNA polymerase sigma L holoenzyme open promoter complex containing TNP-2198
分子名称: (3aM,9S,10bP,14S,15R,16S,17R,18R,19R,20S,21S,25R)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]-5,10,26-trioxo-3,5,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl acetate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Molodtsov, V, Ebright, R.H.
登録日2021-08-19
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens.
J.Med.Chem., 65, 2022
4MIA
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Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with RG7109 (N-{4-[6-tert-butyl-5-methoxy-8-(6-methoxy-2-oxo-2,5-dihydropyridin-3-yl)quinolin-3-yl]phenyl}methanesulfonamide)
分子名称: N-{4-[6-tert-butyl-5-methoxy-8-(6-methoxy-2-oxo-2,5-dihydropyridin-3-yl)quinolin-3-yl]phenyl}methanesulfonamide, RNA-directed RNA polymerase, ZINC ION
著者Harris, S.F, Villasenor, A.G.
登録日2013-08-30
公開日2014-05-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of N-[4-[6-tert-butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a potent inhibitor of the hepatitis C virus NS5B polymerase.
J.Med.Chem., 57, 2014
4MIB
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Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with Compound 48 (N-({(3S)-1-[6-tert-butyl-5-methoxy-8-(2-oxo-1,2-dihydropyridin-3-yl)quinolin-3-yl]pyrrolidin-3-yl}methyl)methanesulfonamide)
分子名称: DIMETHYL SULFOXIDE, N-({(3S)-1-[6-tert-butyl-5-methoxy-8-(2-oxo-1,2-dihydropyridin-3-yl)quinolin-3-yl]pyrrolidin-3-yl}methyl)methanesulfonamide, RNA-DIRECTED RNA POLYMERASE
著者Harris, S.F, Villasenor, A.G.
登録日2013-08-30
公開日2014-05-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of N-[4-[6-tert-butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a potent inhibitor of the hepatitis C virus NS5B polymerase.
J.Med.Chem., 57, 2014
7D7C
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BU of 7d7c by Molmil
CryoEM structure of gp55-dependent RNA polymerase-promoter open complex
分子名称: DNA (nontemplate strand), DNA (template strand), DNA-directed RNA polymerase subunit alpha, ...
著者Shi, J, Wen, A, Jin, S, Feng, Y.
登録日2020-10-03
公開日2021-01-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Transcription activation by a sliding clamp.
Nat Commun, 12, 2021
2P1D
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BU of 2p1d by Molmil
Crystal structure of dengue methyltransferase in complex with GTP and S-Adenosyl-L-homocysteine
分子名称: GUANOSINE-5'-MONOPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Egloff, M.P, Benarooch, D, Marseilles Structural Genomics Program @ AFMB (MSGP)
登録日2007-03-05
公開日2007-03-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献An RNA cap (nucleoside-2'-O)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
EMBO J., 21, 2002
6M6B
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BU of 6m6b by Molmil
Cryo-EM structure of Thermus thermophilus Mfd in complex with RNA polymerase and ATP-gamma-S
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Shi, J, Wen, A, Feng, Y.
登録日2020-03-14
公開日2020-10-14
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of Mfd-dependent transcription termination.
Nucleic Acids Res., 48, 2020
6XJF
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BU of 6xjf by Molmil
X-ray crystal structure of Pyrococcus furiosus general transcription factor TFE-alpha (SeMet labeled protein)
分子名称: Transcription factor E
著者Murakami, K.S, Jun, S.H.
登録日2020-06-23
公開日2020-07-08
最終更新日2021-01-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
2P4V
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BU of 2p4v by Molmil
Crystal structure of the transcript cleavage factor, GreB at 2.6A resolution
分子名称: Transcription elongation factor greB
著者Vassylyeva, M.N, Svetlov, V, Dearborn, A.D, Klyuyev, S, Artsimovitch, I, Vassylyev, D.G.
登録日2007-03-13
公開日2008-01-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The carboxy-terminal coiled-coil of the RNA polymerase beta'-subunit is the main binding site for Gre factors.
Embo Rep., 8, 2007
6KUJ
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BU of 6kuj by Molmil
Structure of influenza D virus polymerase bound to cRNA promoter in class 1
分子名称: 3'-cRNA promoter, 5'-cRNA promoter, Polymerase 3, ...
著者Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
登録日2019-09-02
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of influenza D virus polymerase bound to cRNA promoter in Mode A conformation
NAT NANOTECHNOL, 2019
6L4R
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BU of 6l4r by Molmil
Crystal structure of Enterovirus D68 RdRp
分子名称: RdRp
著者Wang, M.L, Li, L, Zhang, Y, Chen, Y.P, Su, D.
登録日2019-10-21
公開日2020-06-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel.
J.Struct.Biol., 211, 2020
7DG7
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BU of 7dg7 by Molmil
DPBB domain of VCP-like ATPase from Methanopyrus kandleri
分子名称: ATPase of the AAA+ class, IMIDAZOLE, ZINC ION
著者Yagi, S, Tagami, S.
登録日2020-11-11
公開日2021-09-29
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.604 Å)
主引用文献Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
J.Am.Chem.Soc., 143, 2021
7DG9
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DPBB domain of VCP-like ATPase from Aeropyrum pernix
分子名称: Cell division control protein 48, AAA family, ZINC ION
著者Yagi, S, Tagami, S.
登録日2020-11-11
公開日2021-09-29
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
J.Am.Chem.Soc., 143, 2021
7DBO
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BU of 7dbo by Molmil
DPBB domain of VCP-like ATPase from Thermoplasma acidophilum
分子名称: SULFATE ION, VCP-like ATPase
著者Yagi, S, Tagami, S.
登録日2020-10-21
公開日2021-09-29
最終更新日2021-11-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
J.Am.Chem.Soc., 143, 2021
7YOT
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BU of 7yot by Molmil
Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus
分子名称: NDV P protein, RNA-directed RNA polymerase L
著者Chen, Y, Jingyuan, C.
登録日2022-08-02
公開日2023-02-15
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein.
Nat Commun, 14, 2023
7YOU
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BU of 7you by Molmil
Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus
分子名称: NDV P protein, RNA-directed RNA polymerase L
著者Chen, Y, Jingyuan, C, Xiaoying, F.
登録日2022-08-02
公開日2023-02-15
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein.
Nat Commun, 14, 2023
7YOV
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Cryo-EM structure of RNA polymerase in complex with P protein tetramer of Newcastle disease virus
分子名称: NDV P protein, RNA-directed RNA polymerase L
著者Chen, Y, Jingyuan, C, Xiaoying, F.
登録日2022-08-02
公開日2023-02-15
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structure of the Newcastle Disease Virus L protein in complex with tetrameric phosphoprotein.
Nat Commun, 14, 2023
7DI1
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Crystal structure of the rationally designed mkDPBB_sym_86 protein
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, mkDPBB_sym_86 protein
著者Yagi, S, Tagami, S.
登録日2020-11-18
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Seven Amino Acid Types Suffice to Create the Core Fold of RNA Polymerase.
J.Am.Chem.Soc., 143, 2021

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