PDB: 1027 件ウェブページステータス検索Chemie searchBIRD

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7PRM	CRYSTAL STRUCTURE OF HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 13 分子名称: (4~{R})-1-[4-(4-fluorophenyl)phenyl]-4-[4-(furan-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one, 1,2-ETHANEDIOL, Monoglyceride lipase 著者 Grether, U, Gobbi, L, Kuhn, B, Collin, L, Leibrock, L, Heer, D, Wittwer, M, Benz, J. 登録日 2021-09-22 公開日 2022-02-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging. J.Med.Chem., 65, 2022
8IJO	Structure of DNA binding domain of McrBC endonuclease bound to DNA: Y41F-L68F double mutant 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), ... 著者 Adhav, V.A, Saikrishnan, K. 登録日 2023-02-27 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural basis of target recognition by the DNA binding domain of McrBC To Be Published
8IK4	Structure of DNA binding domain of McrBC endonuclease bound to hemimethylated DNA: L68F mutant 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*AP*GP*AP*(5CM)P*CP*GP*GP*TP*AP*G)-3'), DNA (5'-D(*CP*TP*AP*CP*CP*GP*GP*TP*CP*T)-3'), ... 著者 Adhav, V.A, Saikrishnan, K. 登録日 2023-02-28 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of target recognition by the DNA binding domain of McrBC To Be Published
8IJP	Structure of DNA binding domain of McrBC endonuclease bound to DNA: L68Y mutant 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), ... 著者 Adhav, V.A, Saikrishnan, K. 登録日 2023-02-27 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural basis of target recognition by the DNA binding domain of McrBC To Be Published
8IK8	Structure of DNA binding domain of McrBC endonuclease bound to DNA: L68F mutant 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), ... 著者 Adhav, V.A, Saikrishnan, K. 登録日 2023-02-28 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis of target recognition by the DNA binding domain of McrBC To Be Published
8IKD	Structure of DNA binding domain of McrBC endonuclease bound to DNA: Y41F-L68Y double mutant 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*CP*GP*GP*TP*CP*TP*C)-3'), ... 著者 Adhav, V.A, Saikrishnan, K. 登録日 2023-02-28 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of target recognition by the DNA binding domain of McrBC To Be Published
8ILT	Crystal structure of Est30 分子名称: Carboxylesterase 著者 Feng, Y, Luo, Z. 登録日 2023-03-04 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Crystal structure of Est30 To Be Published
2DJH	Crystal structure of the carboxy-terminal ribonuclease domain of Colicin E5 分子名称: 2'-DEOXYURIDINE 3'-MONOPHOSPHATE, 2-AMINO-9-(2-DEOXY-3-O-PHOSPHONOPENTOFURANOSYL)-1,9-DIHYDRO-6H-PURIN-6-ONE, Colicin-E5 著者 Yajima, S, Inoue, S, Ogawa, T, Nonaka, T, Ohsawa, K, Masaki, H. 登録日 2006-04-03 公開日 2007-01-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for sequence-dependent recognition of colicin E5 tRNase by mimicking the mRNA-tRNA interaction Nucleic Acids Res., 34, 2006
2ED6	Crystal Structure of Envelope Protein VP28 from White Spot Syndrome Virus (WSSV) 分子名称: 25kDa structural protein VP25 著者 Hew, C.L, Sivaraman, J, Tang, X.H. 登録日 2007-02-14 公開日 2007-06-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of major envelope proteins VP26 and VP28 from white spot syndrome virus shed light on their evolutionary relationship J.Virol., 81, 2007
2EQP	Solution structure of the stn_TNFRSF12A_TNFR domain of Tumor necrosis factor receptor superfamily member 12A precursor 分子名称: Tumor necrosis factor receptor superfamily member 12A 著者 Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-30 公開日 2008-04-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the stn_TNFRSF12A_TNFR domain of Tumor necrosis factor receptor superfamily member 12A precursor To be Published
2FCG	Solution structure of the C-terminal fragment of human LL-37 分子名称: Antibacterial protein FALL-39, core peptide 著者 Wang, G, Li, X. 登録日 2005-12-12 公開日 2006-05-23 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution Structures of Human LL-37 Fragments and NMR-Based Identification of a Minimal Membrane-Targeting Antimicrobial and Anticancer Region. J.Am.Chem.Soc., 128, 2006
8PTQ	COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5l 分子名称: 1,2-ETHANEDIOL, Monoglyceride lipase, methyl 4-[(2~{S},3~{R})-3-(4-fluorophenyl)-1-(1-methanoylpiperidin-4-yl)-4-oxidanylidene-azetidin-2-yl]benzoate 著者 Butini, S, Grether, U, Benz, J, Leibrock, L, Maramai, S, Papa, A, Carullo, G, Federico, S, Grillo, A, Di Guglielmo, B, Lamponi, S, Gemma, S, Campiani, G. 登録日 2023-07-14 公開日 2024-01-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. J.Med.Chem., 67, 2024
8PTC	COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5d 分子名称: 1,2-ETHANEDIOL, 4-[(3~{R},4~{S})-2-oxidanylidene-3,4-diphenyl-azetidin-1-yl]piperidine-1-carbaldehyde, Monoglyceride lipase 著者 Butini, S, Benz, J, Grether, U, Leibrock, L, Papa, A, Maramai, S, Carullo, G, Federico, S, Grillo, A, Di Guglielmo, B, Lamponi, S, Gemma, S, Campiani, G. 登録日 2023-07-14 公開日 2024-01-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. J.Med.Chem., 67, 2024
8PTR	COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5r 分子名称: (3~{R},4~{S})-4-(1,3-benzodioxol-5-yl)-1-[1-(benzotriazol-1-ylcarbonyl)piperidin-4-yl]-3-(3-fluorophenyl)azetidin-2-one, 1,2-ETHANEDIOL, Monoglyceride lipase 著者 Butini, S, Benz, J, Grether, U, Leibrock, L, Papa, A, Maramai, S, Carullo, G, Federico, S, Grillo, A, Di Guglielmo, B, Lamponi, S, Gemma, S, Campiani, G. 登録日 2023-07-14 公開日 2024-01-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. J.Med.Chem., 67, 2024
2FBS	Solution structure of the LL-37 core peptide bound to detergent micelles 分子名称: Antibacterial protein FALL-39, core peptide 著者 Wang, G, Li, X. 登録日 2005-12-10 公開日 2006-05-23 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution Structures of Human LL-37 Fragments and NMR-Based Identification of a Minimal Membrane-Targeting Antimicrobial and Anticancer Region J.Am.Chem.Soc., 128, 2006
2FBU	Solution structure of the N-terminal fragment of human LL-37 分子名称: Antibacterial protein FALL-39, core peptide 著者 Wang, G, Li, X. 登録日 2005-12-10 公開日 2006-05-23 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution Structures of Human LL-37 Fragments and NMR-Based Identification of a Minimal Membrane-Targeting Antimicrobial and Anticancer Region J.Am.Chem.Soc., 128, 2006
2GOM	Crystal structure of Efb-C from Staphylococcus aureus 分子名称: Fibrinogen-binding protein 著者 Hammel, M, Geisbrecht, B.V. 登録日 2006-04-13 公開日 2007-03-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 A structural basis for complement inhibition by Staphylococcus aureus. Nat.Immunol., 8, 2007
2EDM	Crystal Structure of Envelope Protein VP26 from White Spot Syndrome Virus (WSSV) 分子名称: 22kDa structural protein VP22 著者 Hew, C.L, Tang, X.H, Sivaraman, J. 登録日 2007-02-14 公開日 2007-06-05 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures of Major Envelope Proteins VP26 and VP28 from White Spot Syndrome Virus Shed Light on Their Evolutionary Relationship J.Virol., 81, 2007
4ILJ	Crystal structure of an Prp8p RNaseH W1911A mutant protein 分子名称: Pre-mRNA-splicing factor 8 著者 Weber, G, Heroven, C, Santos, K.F, Wahl, M.C. 登録日 2012-12-31 公開日 2013-03-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.0001 Å) 主引用文献 Structural basis for dual roles of Aar2p in U5 snRNP assembly. Genes Dev., 27, 2013
5ZUN	Crystal structure of human monoacylglycerol lipase in complex with compound 3l 分子名称: (4R)-1-(2'-chloro[1,1'-biphenyl]-3-yl)-4-[4-(1,3-thiazole-2-carbonyl)piperazin-1-yl]pyrrolidin-2-one, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Sogabe, S, Zama, Y, Lane, W, Snell, G. 登録日 2018-05-08 公開日 2018-10-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors J. Med. Chem., 61, 2018
4JK7	Open and closed forms of wild-type human PRP8 RNase H-like domain with bound Mg ion 分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... 著者 Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K, MacMillan, A.M. 登録日 2013-03-09 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
4JKD	Open and closed forms of I1790Y human PRP8 RNase H-like domain with bound Mg ion 分子名称: CHLORIDE ION, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8 著者 Schellenberg, M.J, Wu, T, Ritchie, D.B, Atta, K.A, MacMillan, A.M. 登録日 2013-03-09 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nat.Struct.Mol.Biol., 20, 2013
4KE8	Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with monopalmitoyl glycerol analogue 分子名称: Thermostable monoacylglycerol lipase, tetradecyl hydrogen (R)-(3-azidopropyl)phosphonate 著者 Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. 登録日 2013-04-25 公開日 2013-09-18 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
4KE6	Crystal structure D196N mutant of Monoglyceride lipase from Bacillus sp. H257 in complex with 1-rac-lauroyl glycerol 分子名称: (2R)-2,3-dihydroxypropyl dodecanoate, (4S)-2-METHYL-2,4-PENTANEDIOL, Thermostable monoacylglycerol lipase 著者 Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. 登録日 2013-04-25 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
4KE7	Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with an 1-myristoyl glycerol analogue 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thermostable monoacylglycerol lipase, dodecyl hydrogen (S)-(3-azidopropyl)phosphonate 著者 Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. 登録日 2013-04-25 公開日 2013-09-18 最終更新日 2013-11-20 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013

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