7PDC

The structure of the human tetrameric LL-37 peptide in a channel conformation

Replaces:  5G1J

Summary for 7PDC

• Entry DOI: 10.2210/pdb7pdc/pdb
• Descriptor: Cathelicidin antimicrobial peptide, CHLORIDE ION (3 entities in total)
• Functional Keywords: antimicrobial peptide, ll-37, channel, antimicrobial protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 9044.15

Authors

Zeth, K.,Sancho-Vaello, E. (deposition date: 2021-08-05, release date: 2021-09-08, Last modification date: 2024-01-31)

• Primary citation: Sancho-Vaello, E.,Gil-Carton, D.,Francois, P.,Bonetti, E.J.,Kreir, M.,Pothula, K.R.,Kleinekathofer, U.,Zeth, K.; The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics.; Sci Rep, 10:17356-17356, 2020; PubMed: 33060695; DOI: 10.1038/s41598-020-74401-5

Experimental method

X-RAY DIFFRACTION (1.83 Å)